Test Catalog

Test ID: NSFIB    
Nonalcoholic Steatohepatitis (NASH)-FibroTest, Serum and Plasma

Useful For Suggests clinical disorders or settings where the test may be helpful

Diagnosis and the follow-up of liver fibrosis, steatosis and inflammation

 

Estimating hepatic fibrosis

 

Assessing inflammation for metabolic diseases. It is interpretable for assessing severity of nonalcoholic steatohepatitis (NASH) in patients with nonalcoholic fatty liver disease with steatosis (NAFLD)

 

Assessing steatosis or fatty liver

 

Reassuring patients with steatosis only, without fibrosis

 

Managing patients with severe injuries such as advanced fibrosis and NASH

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
INTNSNASH-FibroTest, InterpretationNoYes
APOAFApolipoprotein A1, SNoYes
A2MFAlpha-2-Macroglobulin, SYes, (Order A2M)Yes
HAPTFHaptoglobin, SYes, (Order HAPT)Yes
ALTFAlanine Aminotransferase (ALT), SYes, (Order ALT)Yes
GGTFGamma Glutamyltransferase (GGT), SYes, (Order GGT)Yes
TBILFBilirubin, Total, SYes, (Order BILIT)Yes
ASTFAspartate Aminotransferase (AST), SYes, (Order AST)Yes
CHOLFCholesterol, Total, SYes, (Order CHOL)Yes
TRIGFTriglycerides, SYes, (Order TRIG)Yes
GLURFGlucose, Fasting, PYes, (Order GLUCF)Yes

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This test is a patented test algorithm developed by BioPredictive. It combines 10 standard biomarkers: gamma-glutamyltransferase (GGT), total bilirubin, alpha-2-macroglobulin, apolipoprotein A1, haptoglobin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), total cholesterol, triglycerides, and fasting glucose. These markers are weighted depending on the patient's age and gender.

 

Testing is compliant with BioPredictive's technical recommendations and approvals.

Method Name A short description of the method used to perform the test

INTNS: Algorithm and interpretation provided through BioPredictive.

APOAF: Automated Turbidimetric Immunoassay

A2MF: Nephelometry

HAPTF: Nephelometry

ALTF: Photometric Rate, L-Alanine with Pyridoxal-5-Phosphate

GGTF: Photometric Rate

TBILF: Photometric, Diazonium Salt (DPD)

ASTF:  Photometric Rate, L-Aspartate with Pyridoxyl-5-Phosphate

CHOLF:  Enzymatic Colorimetric

TRIGF:  Enzymatic Colorimetric

GLURF: Photometric, Hexokinase

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

NASH-FibroTest

Aliases Lists additional common names for a test, as an aid in searching

NASH
Nonalcoholic Steatohepatitis
Steatosis
Steato Test