Test Catalog

Test ID: ALBLD    
Bleeding Diathesis Profile, Limited, Plasma

Useful For Suggests clinical disorders or settings where the test may be helpful

Detection of the more common potential causes of abnormal bleeding (eg, factor deficiencies/hemophilia, von Willebrand disease, factor-specific inhibitors) and a simple screen to evaluate for an inhibitor or severe deficiency of factor XIII (rare)


This test is not useful for assessing platelet function (eg, congenital or acquired disorders such as Glanzmann thrombasthenia, Bernard-Soulier syndrome, storage pool disease, myeloproliferative disease, associated platelet dysfunction), which requires fresh platelets

Profile Information A profile is a group of laboratory tests that are ordered and performed together under a single Mayo Test ID. Profile information lists the test performed, inclusive of the test fee, when a profile is ordered and includes reporting names and individual availability.

Test IDReporting NameAvailable SeparatelyAlways Performed
ALBLILimited Bleed Prof InterpNoYes
PTSCProthrombin Time (PT), PYes, (order PTTP)Yes
APTSCActivated Partial Thrombopl Time, PYes, (order APTTP)Yes
TTSCThrombin Time (Bovine), PYesYes
CLFIBFibrinogen, Clauss, PYes, (order FIBTP)Yes
DIMERD-Dimer, PYes, (order DDITT)Yes
F8ACoag Factor VIII Activity Assay, PYesYes
F_9Coag Factor IX Assay, PYesYes
FXIIIFactor XIII(13),ScrnNoYes
VWAGvon Willebrand Factor Ag, PYesYes
VWACTvon Willebrand Factor Activity, PYesYes

Reflex Tests Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test IDReporting NameAvailable SeparatelyAlways Performed
GBETHGeneral Factor Bethesda Units, PNoNo
5BETHFV Bethesda Units, PNoNo
8BETHFVIII Bethesda Units, PNoNo
9BETHFIX Bethesda Units, PNoNo
F8ISCoag Factor VIII Assay Inhib Scrn,PNoNo
RISTRistocetin Cofactor, PNoNo
FACTVCoag Factor V Assay, PYesNo
F_7Coag Factor VII Assay, PYesNo
F_10Coag Factor X Assay, PYesNo
F_11Coag Factor XI Assay, PYesNo
F_12Coag Factor XII Assay, PYesNo
F_2Coag Factor II Assay, PYesNo
F9_ISFactor IX Inhib ScrnNoNo
F5_ISFactor V Inhib ScrnNoNo
F2_ISFactor II Inhib ScrnNoNo
F7_ISFactor VII Inhib ScrnNoNo
10_ISFactor X Inhib ScrnNoNo
11_ISFactor XI Inhib ScrnNoNo
PNPPlatelet Neutralization ProcedureNoNo
PSGNPlasminogen Activity, PYesNo
PAI1PAI-1 Ag, PYesNo
CH9Chromogenic FIX, PYesNo
ATTIAntithrombin Antigen, PYesNo
ATTFAntithrombin Activity, PYesNo
DRV3DRVVT ConfirmationNoNo
STACLStaclot LA, PNoNo
VWFMPvon Willebrand Factor Multimer, PYes, (order VWFMS)No
DRV1Dilute Russells Viper Venom Time, PYes, (order DRVI1)No
PTFIBPT-Fibrinogen, PNoNo
SOLFMSoluble Fibrin MonomerNoNo
RTSCReptilase Time, PYesNo
A2PIAlpha-2 Plasmin Inhibitor, PYesNo
CHF8Chromogenic FVIII, PYesNo

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Initial testing includes: prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (bovine), fibrinogen, D-dimer, coagulation factor VIII activity assay, coagulation factor IX assay, von Willebrand factor (VWF) antigen, VWF activity, factor XIII screen, and limited bleed profile interpretation.


If PT is >13.9 seconds, then PT mix will be performed at an additional charge.


If APTT is > or =38 seconds, then APTT mix and dilute Russell viper venom time (DRVVT) will be performed at an additional charge.


If DRVVT ratio is > or =1.20, then DRVVT mix and DRVVT confirm will be performed at an additional charge.


If thrombin time is > or =25.0 seconds, then reptilase time will be performed at an additional charge.


If fibrinogen is <150 mg/dL, or clinically indicated, then PT-fibrinogen will be performed at an additional charge.


If D-dimer is >500 ng/mL FEU, then soluble fibrin monomer will be performed at an additional charge.


If APTT mix is > or =38 seconds and thrombin time is <35.0 seconds (no evidence of heparin), then platelet neutralization procedure will be performed at an additional charge.


If VWF activity assay is <55% or VWF activity:VWF antigen ratio is abnormally increased, then VWF ristocetin cofactor activity assay will be performed at an additional charge. 


If VWF antigen is <55%, the VWF activity is <55%, or the VWF activity:VWF antigen ratio is abnormal, then VWF multimer analysis will be performed at an additional charge.


If appropriate, coagulation factor assays or Staclot lupus anticoagulant will be performed at an additional charge to clarify significant abnormalities in the screen test results.


If factor result is below the normal range, the appropriate factor inhibitor screen may be performed along with the Bethesda titering assay, at an additional charge, if inhibitor screen is positive.


See Hemophilia Testing Algorithm in Special Instructions.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

PTSC, APTSC, TTSC, FXIII, F8A, F_9 : Optical Clot-Based

VWAG, VWACT, DIMER: Latex Immunoassay (LIA)

CLFIB: Clauss

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.


Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Bleeding Diath Prof, Limited

Aliases Lists additional common names for a test, as an aid in searching

Bleeding Diathesis Profile, Limited