Detection and characterization of clonal copy number imbalance and loss of heterozygosity associated with hematologic neoplasms
Assisting in the diagnosis and classification of certain hematologic neoplasms
Evaluating the prognosis for patients with certain hematologic neoplasms
DNA extraction is always performed on the specimen prior to hybridization to the microarray. An unstimulated cell culture will be set up on all specimens with adequate volume and held pending additional testing. If additional testing is requested, such as karyotype analysis or FISH, it will be performed at an additional charge.
This test is not appropriate for detecting constitutional/congenital copy number changes or regions of excessive homozygosity. If this test is ordered with a reason for referral indicating a constitutional/congenital disorder, the test will be cancelled and CMACB / Chromosomal Microarray, Congenital, Blood will be performed as the appropriate test.
The following algorithms are available in Special Instructions:
-Aggressive B-cell Lymphoma Diagnostic Algorithm in Special Instructions
-B-Lymphoblastic Leukemia/Lymphoma Algorithm
