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Test ID: CMAH    
Chromosomal Microarray, Hematologic Disorders, Varies

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Useful For Suggests clinical disorders or settings where the test may be helpful

Detection and characterization of clonal copy number imbalance and loss of heterozygosity associated with hematologic neoplasms

 

Assisting in the diagnosis and classification of certain hematologic neoplasms

 

Evaluating the prognosis for patients with certain hematologic neoplasms

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

DNA extraction is always performed on the specimen prior to hybridization to the microarray. An unstimulated cell culture will be set up on all specimens with adequate volume and held pending additional testing. If additional testing is requested, such as karyotype analysis or FISH, it will be performed at an additional charge.

 

This test is not appropriate for detecting constitutional/congenital copy number changes or regions of excessive homozygosity. If this test is ordered with a reason for referral indicating a constitutional/congenital disorder, the test will be cancelled and CMACB / Chromosomal Microarray, Congenital, Blood will be performed as the appropriate test.

 

The following algorithms are available in Special Instructions:

-Aggressive B-cell Lymphoma Diagnostic Algorithm in Special Instructions

-B-Lymphoblastic Leukemia/Lymphoma Algorithm

Special Instructions Library of PDFs including pertinent information and forms related to the test

Method Name A short description of the method used to perform the test

Chromosomal Microarray (CMA) Using Applied Biosystems (Affymetrix) Cytoscan HD

NY State Available Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name Lists a shorter or abbreviated version of the Published Name for a test

Chromosomal Microarray, Hematologic

Aliases Lists additional common names for a test, as an aid in searching

aCGH
Array CGH
Array Comparative Genomic Hybridization
Oligonucleotide Array
Oligo Array
Single Nucleotide Polymorphism (SNP) Array
Whole Genome Array
Microarray
Molecular Karyotype
CytoScan
Hematology Array
Hematologic Array
Heme Array
Loss of Heterozygosity (LOH)
Copy Neutral Loss of Heterozygosity (cnLOH)