Test Catalog

Test ID: ALBSF    
Albumin, Spinal Fluid

Useful For Suggests clinical disorders or settings where the test may be helpful

Assessment of blood-brain barrier permeability

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Elevated albumin concentration in spinal fluid may serve as an indicator of the permeability status of the blood-brain barrier. Comparison to an ALB / Albumin, Serum concentration is recommended.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

0.0-27.0 mg/dL

Interpretation Provides information to assist in interpretation of the test results

Elevated albumin concentrations may be observed in patients with a compromised blood-brain barrier.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Cerebrospinal fluid albumin has limited utility as a standalone test.

Clinical Reference Recommendations for in-depth reading of a clinical nature

Schliep G, Felgenhauer K: Serum-CSF protein gradients, the blood-GSF barrier and the local immune response. J Neurol 1978 May 18;218(2):77-96