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Test Catalog

Test ID: 5AINH    
Factor V Inhibitor Profile, Professional Interpretation

Useful For Suggests clinical disorders or settings where the test may be helpful

Interpretation of testing for factor V inhibitors

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Significant bleeding can result from the presence of a coagulation factor inhibitor and could be life threatening. Whether the inhibitor is present due to hemophilia or of an acquired nature, it greatly complicates the treatment process of a decreased factor level. The titer of the inhibitor may determine the mode of treatment. Bethesda units are a standardization to give a uniform definition of an inhibitor.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Only orderable as a reflex. For more information see 5INHE / Factor V Inhibitor Evaluation, Plasma.

 

An interpretive report will be provided.

Interpretation Provides information to assist in interpretation of the test results

An interpretive report will be provided when testing is complete.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

No specific cautionary statements

Clinical Reference Recommendations for in-depth reading of a clinical nature

1. Biggs R, Bidwell E: A method for the study of antihemophiliac globulin inhibitors with reference to six cases. Br J Haematol 1959;5:379-395

2. Hoyer LW: Factor VIII inhibitors In Progress in Clinical and Biological Research. Vol 150. Edited by LW Hoyer, R Alan Liss Inc, New York, 1984, pp 87-98

3. Kasper C, Aledort L: A more uniform measurement of factor VIII inhibitors. Thromb Diath Haemorrh. (Stuttg) 1975;34:869

4. Kasper C, Ewing N: Acquired inhibitors of plasma coagulation factors. J Med Tech 1986;38:431-439

5. Laboratory Hematology Practice. Edited by K Kottke-Marchant. Wiley Blackwell Publishing. 2012