Test Catalog

Test ID: SUDC    
Sudden Cardiac Death Pathology Consultation

Useful For Suggests clinical disorders or settings where the test may be helpful

Identifying specific causes contributing to sudden cardiac death

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

An interpretation will be provided by Mayo staff pathologists within a formal pathology report that is sent to the referring Medical Examiner.


Appropriate stains and other ancillary testing may be performed and charged separately.

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Sudden, unexpected death in individuals less than 40 years old with a strong probability of cardiac disease (including cases of obvious cardiomyopathy, with likely genetic underpinning). This evaluation is offered to provide the careful dissection and diagnostic experience that may be needed for subtle or overt cases of cardiovascular disease.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

The laboratory will provide a pathology consultation.

Interpretation Provides information to assist in interpretation of the test results

This request will be processed as a consultation. Appropriate stains and ancillary testing will be performed and an interpretation provided.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Clinical Reference Recommendations for in-depth reading of a clinical nature

1. Baudhuin LM, Leduc C, Train LJ, et al: Technical Advances for the Clinical Genomic Evaluation of Sudden Cardiac Death: Verification of Next-Generation Sequencing Panels for Hereditary Cardiovascular Conditions Using Formalin-Fixed Paraffin-Embedded Tissues and Dried Blood Spots. Circ Cardiovasc Genet. 2017 Dec;10(6). doi: 10.1161/CIRCGENETICS.117.001844

2. Ackerman JP, Bartos DC, Kapplinger JD, et al: The Promise and Peril of Precision Medicine: Phenotyping Still Matters Most. Mayo Clin Proc. 2016 Oct 8. pii: S0025-6196(16)30463-3. doi: 10.1016/j.mayocp.2016.08.008