Test Catalog

Test ID: ADICI    
Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile Interpretation

Useful For Suggests clinical disorders or settings where the test may be helpful

Establishing laboratory evidence of disseminated intravascular coagulation (DIC)

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Disseminated intravascular coagulation (DIC)/intravascular coagulation and fibrinolysis (ICF), collectively termed DIC/ICF is a consumptive hemorrhagic and microthrombotic disorder that manifests as clinical bleeding or thrombosis. Conditions associated with DIC/ICF can include; sepsis, trauma (head injury, severe tissue injury), obstetric complications (amniotic fluid embolism, abruptio placentae), malignancies, vascular disorders (hemangiomas, aortic aneurysm), and immunologic disorders. 


These disorders can cause formation of thrombin and fibrin intravascularly, which can result in widespread fibrin deposition contributing to thrombosis and organ failure or, conversely, can result in bleeding due to consumption of coagulation proteins and platelets. DIC/ICF is not a disease; rather it is a syndrome that is secondary to an underlying disorder.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Only orderable as part of a profile. For more information see ADIC / Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma.


An interpretive report will be provided.

Interpretation Provides information to assist in interpretation of the test results

An interpretive report will be provided.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

No significant cautionary statements.

Clinical Reference Recommendations for in-depth reading of a clinical nature

Boender J: A Diagnostic Approach to Mild Bleeding Disorders Journal of Thrombosis and Haemostasis 2016;14:1507-1516