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THCG - Overview: Human Chorionic Gonadotropin (hCG), Quantitative, Pregnancy, Serum

Early detection of pregnancy Investigation of suspected ectopic pregnancy or other pregnancy-related complications Monitoring in vitro fertilization patients This test is not useful for detecting or monitoring tumors or gestational...

GLYCC - Overview: Glycine Receptor Alpha1 IgG, Cell Binding Assay, Spinal Fluid

Evaluating patients with suspected autoimmune stiff-person spectrum disorders (stiff-person syndrome, stiff-limb, stiff trunk, or progressive encephalomyelitis with rigidity and myoclonus [PERM]) using spinal fluids specimens

GLYCS - Overview: Glycine Receptor Alpha1 IgG, Cell Binding Assay, Serum

Evaluating patients with suspected autoimmune stiff-person spectrum disorders (stiff-person syndrome, stiff-limb, stiff trunk or progressive encephalomyelitis with rigidity and myoclonus [PERM]) using serum specimens

KIMEL - Overview: Ki67 + Melan A Immunostain, Technical Component Only

Ki67 is a marker of proliferation in neoplasms Melan A aids in the identification of melanoma

MUSK - Overview: Muscle-Specific Kinase (MuSK) Autoantibody, Serum

Diagnosis of autoimmune muscle-specific kinase (MuSK) myasthenia gravis Second-order test to aid in the diagnosis of autoimmune myasthenia gravis when first-line serologic tests are negative Establishing a quantitative baseline value...

FMSS2 - Overview: Maternal Serum Screening, Integrated, Specimen #2, Alpha Fetoprotein, Hcg, Estriol, and Inhibin A

Helpful to identify pregnancies at increased risk of having a child with Down syndrome (trisomy 21), Open Neural Tube Defect (ONTD, spina bifida) and trisomy 18 (T18). This test is not diagnostic. The patient information provided with the...

VITB3 - Overview: Vitamin B3 and Metabolites, Plasma

Assisting in the diagnosis of suspected vitamin B3 deficiency or toxicity May be useful in determining response to therapy

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Urinary Steroid Profile Assay

Understanding the difference between benign and malignant adrenal tumors has alway been difficult; this new assay will assist with this medical challenge.

Urinary Steroid Profile [Test in Focus] - Insights

Irina Bancos, M.D. gives an overview of this test available through Mayo Clinic Laboratories. She discusses when this testing should be ordered, how this testing compares to other testing approaches, and what clinical action can be taken...

steroid_pathways.pdf

01/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Steroid Pathways Mineralocorticoids CYP17A1 = Cytochrome P450 Family 17 Subfamily A Member 1 HSD3B1/HSD3B2 =...

GFAP: Novel Test for a Newly Identified Meningoencephalomyelitis - Insights

Mayo Clinic Laboratories is the only laboratory in the world to offer testing for a novel form of autoimmune meningoencephalomyelitis. Known as autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy, the condition was identified...

Comprehensive testing leads to targeted treatment for rare autoimmune encephalitis antibody: Spencer Lodin - Insights

What started as a persistent headache for Spencer Lodin soon devolved into slowed speech, seizures, and hallucinations, symptoms which stumped ER doctors into thinking he had meningitis or was suffering from psychosis. Finally, specialized...