PTOX - Overview: Toxoplasma gondii, Molecular Detection, PCR, Varies
Supporting the diagnosis of acute cerebral, ocular, disseminated, or congenital toxoplasmosis This test should not be used to screen healthy patients.
PSYR - Overview: Psychosine, Whole Blood
Aiding in the biochemical diagnosis of Krabbe disease using whole blood specimens Follow-up of individuals affected with Krabbe disease Follow-up testing after an abnormal newborn screening result for Krabbe disease Monitoring of...
Detecting IDH1 R132 and IDH2 R140 and R172 mutations in acute myeloid leukemia patients at the time of diagnosis to guide targeted therapy Monitoring minimal residual disease during the clinical and therapeutic course
RTQPC - Overview: Abnormal Prion Protein, Real-Time Quaking Induced Conversion, Spinal Fluid
Aiding in diagnosing sporadic Creutzfeldt-Jakob disease or other prion disease in patients with a rapidly progressive dementia
QMPTS - Overview: Monoclonal Protein Isotype, Quantitative, Serum
Aiding in the diagnosis and monitoring of monoclonal gammopathies if used in conjunction with free light chain studies This test alone is not considered an adequate screen for monoclonal gammopathies.
ML1HM - Overview: MLH1 Hypermethylation Analysis, Tumor
An adjunct to TMSI / Microsatellite Instability, Tumor and IHC / Mismatch Repair (MMR) Protein Immunohistochemistry Only, Tumor when colon or endometrial tumor demonstrates microsatellite instability (MSI-H) and loss of MLH1 protein...
SZMON - Overview: Sezary Monitoring Flow Cytometry, Blood
Monitoring response to therapy in patients with previously diagnosed Sezary syndrome or mycosis fungoides
KCSFP - Overview: Immunoglobulin Kappa Free Light Chain, Spinal Fluid
Diagnosis of multiple sclerosis and other demyelinating conditions
ROPAN - Overview: Ro52 and Ro60 Antibodies, IgG, Serum
Evaluating patients at risk for connective tissue disease with or without interstitial lung disease Differentiation of antibodies to Ro52 and Ro60 in patients known to be positive for anti-SS-A (Ro) antibodies
STHPV - Overview: ThinPrep Screen with Human Papillomavirus (HPV) Reflex, Varies
Managing and triaging of patients, aged 21 years or older, with abnormal Pap results Screening for detection of high-risk (HR) human papillomavirus (HPV) genotypes associated with the development of cervical cancer Aids in triaging...
A second-level test after lymphocyte proliferation to mitogens (specifically phytohemagglutinin) has been assessed Evaluating patients suspected of having impairment in cellular immunity Evaluation of T-cell function in patients with...
DTHPV - Overview: ThinPrep Diagnostic with Human Papillomavirus (HPV) Reflex, Varies
Management and triage of patients aged 21 years or older with abnormal Papanicolaou (Pap) results Diagnostic test for detection of human papillomavirus (HPV) high-risk genotypes associated with the development of cervical cancer Results...
GID2 - Overview: Gastrointestinal Dysmotility, Autoimmune/Paraneoplastic Evaluation, Serum
Investigating unexplained weight loss, early satiety, anorexia, nausea, vomiting, constipation, or diarrhea in a patient with a past or family history of cancer or autoimmunity Directing a focused search for cancer Investigating...
PTEN - Overview: Phosphatase and Tensin Homolog (PTEN) Immunostain, Technical Component Only
Diagnosis of intraductal prostate carcinoma
IL5P - Overview: Interleukin 5, Plasma
Evaluation of patients with disorders known to be associated with hypereosinophilia
APHTC - Overview: Amphiphysin Antibody Titer Assay, Spinal Fluid
Evaluating patients with recent onset of a subacute neurological disorder for which a paraneoplastic basis might be suspected, particularly if the patient has a previous history, risk factors, or family history of cancer, especially lung or...
CSPCF - Overview: Plasma Cell Proliferative Disorder, Pre-Analysis Cell Sorting, Bone Marrow
Aiding in the diagnosis of new cases of multiple myeloma or other plasma cell proliferative disorders Sorting plasma cells for fluorescence in situ hybridization analysis
CTSK - Overview: Cathepsin K Immunostain, Technical Component Only
Evaluation for perivascular epithelioid cell neoplasms (PEComas), alveolar soft part sarcoma, and translocation-associated renal cell carcinomas
SOX11 - Overview: SOX11 Immunostain, Technical Component Only
Identification of mantle cell lymphomas
GATA3 - Overview: GATA Binding Protein 3 Immunostain, Technical Component Only
Characterizing carcinomas, including primary bladder and breast carcinomas, and some types of mesenchymal and neuroectodermal tumors
HCQ - Overview: Hydroxychloroquine, Serum
Monitoring serum hydroxychloroquine concentrations, assessing compliance, and adjusting dosage in patients
Reporting an end titer result in spinal fluid specimens Distinguishing, in spinal fluid, autoimmune GFAP astrocytopathy from infectious meningoencephalitis and idiopathic inflammatory central nervous system (CNS) disorders such as multiple...
Reporting an end titer result in serum specimens Distinguishing autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy from infectious meningoencephalitis and idiopathic inflammatory central nervous system (CNS) disorders such as...
IHCFH - Overview: Fumarate Hydratase Immunostain, Technical Component Only
Identifying fumarate hydratase-deficient neoplasms Supporting the diagnosis of an atypical smooth muscle tumor over leiomyosarcoma
IDH2 - Overview: IHD2, R172K Mutation, Immunostain, Technical Component Only
Identification of IDH2 R172K mutant protein in angioimmunoblastic T-cell lymphoma or acute myeloid leukemia
IA2 - Overview: Islet Antigen 2 (IA-2) Antibody, Serum
Clinical distinction of type 1 from type 2 diabetes mellitus Identification of individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes) Prediction of future need for insulin treatment in...
ISLET - Overview: Islet 1 Immunostain, Technical Component Only
Identification of endocrine tumors
MTAP - Overview: Methylthioadenosine Phosphorylase (MTAP) Immunostain, Tech Only
Aiding in the diagnosis of malignant mesothelioma
ALKOT - Overview: Anaplastic Lymphoma Kinase (ALK [OTI1A4]) Immunostain, Technical Component Only
Identification of anaplastic lymphoma kinase overexpression Diagnosis of inflammatory myofibroblastic tumor and anaplastic large cell lymphoma
BRG1 - Overview: BRG1 (SMARCA4) Immunostain, Technical Component Only
Diagnosing ovarian small cell carcinoma of hypercalcemic type (SCCOHT)
CD303 - Overview: CD303 (BDCA-2) Immunostain, Technical Component Only
Diagnosis of blastic plasmacytoid dendritic cell neoplasm
MUCN4 - Overview: Mucin 4, Immunostain, Technical Component Only
Aids in the differentiation of sarcomatoid carcinoma from sarcomatoid mesothelioma
Aids in distinguishing solitary fibrous tumor from morphologic mimics
SSTR2 - Overview: Somatostatin Receptor 2 (SSTR2), Immunostain, Technical Component Only
Aids in the identification of neuroendocrine tumors
STFR - Overview: Soluble Transferrin Receptor (sTfR), Serum
Evaluation of suspected iron deficiency in patients who may have inflammation, infection, or chronic disease and other conditions in which ferritin concentration does not correlate with iron status, including: -Cystic fibrosis patients who...
Identification of neural epidermal growth factor-like 1 (NELL-1) protein primary membranous nephropathy
C1ES - Overview: C1 Esterase Inhibitor Antigen, Serum
Diagnosis of hereditary angioedema Monitoring levels of C1 esterase inhibitor in response to therapy
GATAB - Overview: GATA-Binding Protein 3 Immunostain, Technical Component Only, Bone Marrow,
Characterizing carcinomas, including primary bladder and breast carcinomas, and some types of mesenchymal and neuroectodermal tumors
Determination of T-cell clonality in T-cell neoplasms
TRBC1 - Overview: T-Cell Receptor Constant Beta Chain (TRBC1) Immunostain, Technical Component Only
Determination of T-cell clonality in T-cell neoplasms
APHTS - Overview: Amphiphysin Antibody Titer Assay, Serum
Evaluating patients with recent onset of a subacute neurological disorder for which a paraneoplastic basis might be suspected, particularly if the patient has a previous history, risk factors, or family history of cancer, especially lung or...
Providing a genetic evaluation for patients with a personal or family history suggestive of hereditary hemorrhagic telangiectasia (HHT), cerebral cavernous malformation (CCM), capillary malformation-arteriovenous malformation syndrome...
PMARG - Overview: Postmortem Arrhythmia Gene Panel, Tissue
Providing a comprehensive postmortem genetic evaluation in the setting of a sudden death suspicious for cardiac arrhythmia or with a personal or family history suggestive of a hereditary form of cardiac arrhythmia Identifying a...
PKLRZ - Overview: PKLR Full Gene Analysis, Varies
Aiding in the diagnosis of pyruvate kinase (PK) deficiency Ascertaining a causative variant in the PKLR gene of patients with low or relatively low levels of erythrocytic PK enzymatic activity Ascertaining carrier status of family members...
STK1Z - Overview: Peutz-Jeghers Syndrome, STK11, Full Gene Analysis, Varies
Evaluating patients with a personal or family history suggestive of Peutz-Jeghers syndrome (PJS) Establishing a diagnosis of PJS allowing for targeted cancer surveillance based on associated risks Identifying variants within genes known...
NGSFX - Overview: Reanalysis of Acute Myeloid Leukemia 4- or 11- Gene Panels, Additional Genes
Comprehensive reanalysis of a larger set of genes/gene regions when a more targeted gene panel was previously performed in this laboratory Evaluation of known or suspected hematologic neoplasms, specifically of myeloid origin (eg, acute...
HMUOE - Overview: Heavy Metal Occupational Exposure, with Reflex, Random, Urine
Preferred screening test for detection of arsenic, cadmium, mercury, and lead due to occupational exposure using random urine specimens
HMUCR - Overview: Heavy Metal/Creatinine Ratio, with Reflex, Random, Urine
Preferred screening test for detection of arsenic, cadmium, mercury, and lead in random urine specimens
ADPKP - Overview: Focused Autosomal Dominant Polycystic Kidney Disease Gene Panel, Varies
Providing a genetic evaluation for patients with a personal or family history suggestive of autosomal dominant polycystic kidney disease Establishing a diagnosis of autosomal dominant polycystic kidney disease
MCLNM - Overview: MayoComplete Lung Cancer Mutations, Next-Generation Sequencing, Tumor
Diagnosis and management of patients with lung cancer Assessing microsatellite instability
Hypersensitivity Testing and Initial Patient Management Algorithm 1. Saag M, Balu R, Phillips E, et al. High sensitivity of human leukocyte antigen-b*5701......
international-shipping-guide-french.pdf
G U ID E D ’EXPÉD ITIO N IN TERN ATIO N ALEENVOYER DES TESTS À LA MAYO CLINIC DEPUIS LE MONDE ENTIER 2 | GUIDE D’EXPÉDITION INTERNATIONALE TABLE DES MATIÈRES EXPÉDIER AUX ÉTATS-UNIS DEPUIS LE MONDE ENTIER 3 Avant...
Pediatric neuro-oncology informative cases - Insights
Neuro-oncology is a complex field undergoing rapid changes with the advancement and evolution of sophisticated genetic testing. Evidence continues to grow in support of broad molecular and cytogenetic analysis for patients with brain...
The diagnosis of Myeloproliferative Neoplasm (MPN) must include an integrated approach and combine the clinical findings with laboratory results. In our latest “Hot Topic,” Rong He, M.D., discusses the subclassification of MPNs and the use...
MCL Autoimmune Axonal Neuropathy A Comprehensive Testing Approach MC2775425
MCL Autoimmune Axonal Neuropathy Comprehensive Testing Approach NEUROLOGY AUTOIMMUNE AXONAL NEUROPATHY COMPREHENSIVE TESTING APPROACH Patients neuropathy variable sensory motor disturbance loss exaggerated