PALB - Overview: Prealbumin, Serum
Assessing nutritional status, especially in monitoring the response to nutritional support in the acutely ill patient
PA - Overview: Procainamide and N-Acetylprocainamide, Serum
Monitoring therapy with procainamide Assessing compliance Evaluating procainamide toxicity
CRUO - Overview: Chromium Occupational Exposure, Random, Urine
Screening for occupational exposure
SP5TS - Overview: Septin-5 Antibody, Tissue Immunofluorescence Titer, Serum
Detecting septin-5 IgG in serum specimens Reporting an end titer result from serum specimens
SDEX - Overview: Sickle Solubility, Blood
Screening for presence or absence of hemoglobin (Hb) S (sickle cell disease)
WGSR - Overview: Whole Genome Sequencing Reanalysis, Varies
Identifying a diagnosis or additional variants associated with the phenotype in patients who previously have had a negative or inconclusive whole genome sequencing test Reanalyzing whole genome sequencing data when a patient (proband)...
HLLFH - Overview: Hematologic Disorders, Leukemia/Lymphoma; Flow Hold, Varies
Evaluating lymphocytoses of undetermined etiology Identifying B- and T-cell lymphoproliferative disorders involving blood and bone marrow Distinguishing acute lymphoblastic leukemia (ALL) from acute myeloid leukemia (AML) Immunologic...
NHEP - Overview: Hereditary Erythrocytosis Gene Panel, Next-Generation Sequencing, Varies
Evaluating an individual with JAK2-V617F negative erythrocytosis associated with lifelong sustained increased red blood cell (RBC) mass, elevated RBC count, hemoglobin, or hematocrit Providing an extensive genetic evaluation for patients...
PIK3T - Overview: PIK3CA Mutation Analysis, Tumor
Identification of hormone receptor positive and human epidermal growth factor receptor 2 negative (HR+/HER2-) advanced breast cancer tumors that may be eligible for treatment with targeted kinase inhibitor therapy (eg, alpelisib).
PIPU - Overview: Pipecolic Acid, Random, Urine
Differentiating between disorders of peroxisomal biogenesis (eg, Zellweger syndrome) and disorders with loss of a single peroxisomal function Detecting abnormal elevations of pipecolic acid in urine
PCHE1 - Overview: Pseudocholinesterase, Total, Serum
Monitoring exposure to organophosphorus insecticides and herbicides Monitoring patients with liver disease, particularly those undergoing liver transplantation Identifying patients who are homozygous or heterozygous for an atypical gene...
FRT4D - Overview: T4 (Thyroxine), Free, Dialysis, Serum
Determining thyroid status of sick, hospitalized patients Determining thyroid status of patients in whom abnormal binding proteins have been identified Possibly useful in pediatric patients
TREE3 - Overview: Tree Panel #3, Serum
Establishing a diagnosis of an allergy to tress in panel #3 Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...
TREE4 - Overview: Tree Panel #4, Serum
Establishing a diagnosis of an allergy to trees in panel #4 Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm...
WEED2 - Overview: Weed Panel # 2, Serum
Establishing a diagnosis of an allergy to English plantain, lamb's quarters, mugwort, scale, and Western ragweed allergen Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic...
WEED4 - Overview: Weed Panel # 4, Serum
Establishing a diagnosis of an allergy to giant ragweed, short ragweed, and Western ragweed Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic...
YMCRO - Overview: Y Chromosome Microdeletions, Molecular Detection, Varies
Evaluating men with azoospermia, severe oligozoospermia, or otherwise unexplained male factor infertility
TIUCR - Overview: Titanium/Creatinine Ratio, Random, Urine
Monitoring exposure and elimination of titanium
CBRP - Overview: Coxiella burnetii (Q fever), Molecular Detection, PCR, Varies
Aiding in the diagnosis of Coxiella burnetii infection (eg, Q fever) using tissue specimens
ROM - Overview: Measles (Rubeola) Antibodies, IgM, Serum
Determining acute-phase infection with rubeola (measles) virus using IgM antibody testing Aiding in the identification of nonimmune individuals through IgM antibody testing
PAX8 - Overview: PAX8 Immunostain, Technical Component Only
Aids in the identification of renal cell carcinomas, as well as papillary thyroid carcinomas and tumors of Mullerian origin
Diagnosing syphilis
RSBV - Overview: Rare Subepithelial Autoimmune Blistering Disease Variants, Serum
Aiding in the diagnosis of rare subepithelial autoimmune blistering diseases, including anti-laminin 332 pemphigoid, anti-p200 pemphigoid, epidermolysis bullosa acquisita, and systemic bullous lupus erythematosus
PTHRP - Overview: Parathyroid Hormone-Related Peptide, Plasma
Aiding in the evaluation of individuals with hypercalcemia of unknown origin Aiding in the evaluation of individuals with suspected humoral hypercalcemia of malignancy The test should not be used to exclude cancer or screen individuals...
P53 - Overview: p53 Immunostain, Technical Component Only
Aiding in the identification of neoplastic cells
OXU - Overview: Oxalate, 24 Hour, Urine
Monitoring therapy for kidney stones using 24-hour urine collections Identifying increased urinary oxalate as a risk factor for stone formation Diagnosis of primary or secondary hyperoxaluria
HD1 - Overview: House Dust Panel, Serum
Establishing a diagnosis of an allergy to cockroach, Dermatophagoides farinea, Dermatophagoides pteronyssinus, and house dust/H-S lab Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible...
HG34W - Overview: Histone 3.3 G34W (H3F3A G34W) Immunostain, Technical Component Only
Aiding in the diagnosis of giant cell tumor of bone
GDU - Overview: Gadolinium, 24 Hour, Urine
Assessing chronic exposure and monitoring effectiveness of dialysis in a 24-hour urine collection
FUFXS - Overview: Fragile X, Follow-up Analysis
Confirming the methylation status of the repeat expansion allele in the FMR1 gene, to aid the diagnosis of FMR1-related disorders
GAL3 - Overview: Galectin-3, Serum
Aiding in the prognosis for patients diagnosed with heart failure Risk stratification of patients with heart failure An early indication of treatment failure and as a therapeutic target
BFLA1 - Overview: Lipid Analysis, Body Fluid
Distinguishing between chylous and nonchylous effusions
MUCN6 - Overview: Mucin 6, Immunostain, Technical Component Only
Aiding in subtyping intraductal papillary mucinous neoplasms as part of an immunopanel
MUCN5 - Overview: Mucin 5AC, Immunostain, Technical Component Only
Aiding in subtyping intraductal papillary mucinous neoplasms
JCPCR - Overview: JC Virus, Molecular Detection, PCR, Spinal Fluid
Aiding in diagnosing progressive multifocal leukoencephalopathy due to JC virus This test is not to be used as a diagnostic tool for Creutzfeldt-Jakob disease This test is not recommended for screening asymptomatic patients
AAMSD - Overview: Amino Acids, Maple Syrup Urine Disease Panel, Plasma
Follow-up of patients with maple syrup urine disease Monitoring of dietary compliance for patients with maple syrup urine disease
Susceptibility testing of Mycobacterium tuberculosis complex isolates growing in pure culture.
APOLB - Overview: Apolipoprotein B, Serum
Assessment of cardiovascular risk Follow-up studies in individuals with basic lipid measures inconsistent with risk factors or clinical presentation Definitive studies of cardiac risk factors in individuals with significant family...
BAP1 - Overview: BAP1 Immunostain, Technical Component Only
As part of a panel of immunostains where loss of staining can be used as a marker of various neoplasms
BORDG - Overview: Bordetella pertussis Antibody, IgG, Serum
Diagnosis of recent infection with Bordetella pertussis in patients with symptoms consistent with whooping cough for 2 or more weeks This test should not be used in neonates, young infants or in children between the ages of 4 to 7 years as...
CATN - Overview: Calcitonin, Serum
Aids in the diagnosis and follow-up of medullary thyroid carcinoma Aids in the evaluation of multiple endocrine neoplasia type II and familial medullary thyroid carcinoma This test is not useful for evaluating calcium metabolic...
PNTFT - Overview: Phenytoin, Total and Free, Serum
Monitoring for appropriate therapeutic concentration of both free and total phenytoin: free phenytoin level is the best indicator of adequate therapy in renal failure
SSCTU - Overview: S-Sulfocysteine Panel, Urine
Diagnosis of molybdenum cofactor deficiency, isolated sulfite oxidase deficiency, and hereditary xanthinuria Monitoring patients with molybdenum cofactor deficiency or isolated sulfite oxidase deficiency who are on treatment
MOLD1 - Overview: Mold Panel, Serum
Establishing a diagnosis of an allergy to mold Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic response and/or anaphylactic episode -To confirm sensitization prior to...
MYCOM - Overview: Mycoplasma pneumoniae Antibodies, IgM, Serum
Screening for IgM antibodies in the indication of recent or past exposure to Mycoplasma pneumoniae
Evaluation of Rac2 deficiency and RAC2 gain of function
TQ10 - Overview: Coenzyme Q10, Total, Plasma
Diagnosis of primary coenzyme Q10 (CoQ10) deficiencies in some patients who are not supplemented with CoQ10 Monitoring patients receiving statin therapy Monitoring CoQ10 status during treatment of various degenerative conditions,...
CHLBF - Overview: Cholesterol, Body Fluid
Aiding in the diagnosis of a cholesterol effusion or cholesterol-rich pseudochylous effusion in body fluids Distinguishing between chylous and pseudochylous pleural effusions Distinguishing between malignant and nonmalignant ascites
WEED3 - Overview: Weed Panel # 3, Serum
Establishing a diagnosis of an allergy to English plantain, lamb's quarters, red sorrel, and Russian thistle allergen Defining the allergen responsible for eliciting signs and symptoms Identifying allergens: -Responsible for allergic...
JAKXM - Overview: JAK2 Exon 12 and Other Non-V617F Mutation Detection, Bone Marrow
Second-order testing to aid in the distinction between a reactive cytosis and a myeloproliferative neoplasm, particularly when a diagnosis of polycythemia is being entertained; for use with bone marrow specimens
NELL-1 [Test in Focus] - Insights
D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic...
Looking Back on Clinical Chemistry 1 - Insights
in the Mayo Clinic Medical Laboratory Science program, takes a look back on her Clinical Chemistry 1 course....
Mayo Clinic Ranked No. 1 Hospital Nationwide by U.S. News & World Report - Insights
Report’s 29th annual "Best Hospitals Honor Roll" published online on August 14. Mayo Clinic also ranked No. 1 in more specialties than any other hospital in the country....
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT to diagnose type 1 narcolepsy....
Week in Review: November 1 - Insights
Top highlights include: Facebook launches into the digital space of healthcare, medical breakthrough for Ebola, and how the brain makes memories.