MP9W - Overview: Mucopolysaccharidoses, Nine-Enzyme Panel, Leukocytes
Supporting the biochemical diagnosis of mucopolysaccharidoses types II, IIIA, IIIB, IIIC, IIID, IVA, IVB, VI, and VII, and of multiple sulfatase deficiency This test is not useful for carrier detection.
ROMA - Overview: ROMA Score (Ovarian Malignancy Risk Algorithm), Serum
Risk assessment for finding an ovarian malignancy during surgery in women who present with an adnexal mass The test is not intended as a screening or stand-alone diagnostic assay for ovarian cancer.
LUCHM - Overview: LiquidHALLMARK ctDNA and ctRNA
As an alternative to invasive tissue biopsies to assist in tumor profiling for diagnosis, predicting prognosis, and identifying targeted therapies for the treatment and management of patients with a solid tumor This test is not useful for...
BCGR - Overview: Immunoglobulin Gene Rearrangement, Blood
Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using whole blood specimens Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent neoplasm by...
BCGBM - Overview: Immunoglobulin Gene Rearrangement, PCR, Bone Marrow
Determining whether a B-cell or plasma cell population is polyclonal or monoclonal using bone marrow specimens Identifying neoplastic cells as having B-cell or plasma cell differentiation Monitoring for a persistent neoplasm by...
PTH2 - Overview: Parathyroid Hormone, Serum
Diagnosis and differential diagnosis of hypercalcemia Diagnosis of primary, secondary, and tertiary hyperparathyroidism Diagnosis of hypoparathyroidism Monitoring kidney failure patients for possible renal osteodystrophy
AMISO - Overview: Amylase, Isoenzymes, Serum
Ruling out salivary amylase as the cause of elevated serum amylase
B12 - Overview: Vitamin B12 Assay, Serum
Investigation of macrocytic anemia Workup of deficiencies seen in megaloblastic anemias
GUSBB - Overview: Beta-Glucuronidase, Blood Spot
Supporting the biochemical diagnosis of mucopolysaccharidosis VII (MPS VII, Sly syndrome) This test is not useful for determining carrier status for MPS VII.
TPBF - Overview: Protein, Total, Body Fluid
Identification of exudative pleural effusions Differentiating hepatic from other causes of ascites that have elevated serum ascites albumin gradient using peritoneal fluid
HAVTA - Overview: Hepatitis A Virus Total Antibodies, Serum
Detection of recent or previous exposure or immunity to hepatitis A. This test should not be used as a screening or confirmatory test for blood or solid or soft tissue donor specimens.
RAVU - Overview: Ravulizumab, Serum
Assessing the response to ravulizumab therapy Assessing the need for dose escalation Evaluating the potential for dose deescalation or discontinuation of therapy in remission states Monitoring patients who need to be above a certain...
PT217 - Overview: Phospho-Tau 217, Plasma
Evaluation of individuals, aged 50 years and older, presenting with cognitive impairment who are being assessed for Alzheimer disease and other causes of cognitive decline This test is not intended as a screening test for Alzheimer...
HRSPF - Overview: Horse Dander, IgE with Reflex to Horse Dander Component, IgE, Serum
Evaluating patients with suspected horse dander allergy
MALP - Overview: Malabsorption Evaluation Panel, Feces
Evaluation of patients with suspected malabsorption, as suggested by chronic diarrhea, unexplained weight loss, or nutritional deficiencies Differentiation between causes of malabsorption, specifically inflammatory conditions, pancreatic...
ADNA1 - Overview: Double-Stranded DNA (dsDNA) Antibodies, IgG, Serum
Evaluating patients with clinical features or at-risk for systemic lupus erythematosus (SLE) Monitoring disease activity, as an adjunct test, in patients with SLE previously positive for double-stranded DNA IgG antibodies
MPNML - Overview: MPL Exon 10 Sequencing, Reflex, Varies
Aiding in the distinction between a reactive cytosis and a myeloproliferative neoplasm when JAK2 V617F testing result is negative Evaluates for variants in MPL in an algorithmic process for MPNCM / Myeloproliferative Neoplasm, CALR with...
RNP - Overview: RNP Antibodies, IgG, Serum
Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive Testing for ribonucleoprotein particle antibodies is not useful in patients without demonstrable...
MSDBS - Overview: Multiple Sulfatase Deficiency, Blood Spot
Supporting the biochemical diagnosis of multiple sulfatase deficiency This test is not useful for carrier detection.
Evaluating for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and related demyelinating peripheral neuropathies
ANA2 - Overview: Antinuclear Antibodies (ANA), Serum
Evaluating patients at-risk for antinuclear antibodies-associated systemic autoimmune rheumatic disease particularly systemic lupus erythematosus, Sjogren syndrome, and mixed connective tissue disease
WBGDR - Overview: Beta-Globin Gene Cluster Deletion/Duplication, Blood
Determining the etiology of hereditary persistence of fetal hemoglobin (HPFH), delta-beta thalassemia, or other large deletions involving the beta-globin gene cluster Diagnosing less common causes of beta-thalassemia; these large...
MPS3B - Overview: Mucopolysaccharidosis III, Three-Enzyme Panel, Blood Spot
Supporting the biochemical diagnosis of mucopolysaccharidoses types IIIA, IIIB, IIIC This test is not useful for carrier detection.
I2SB - Overview: Iduronate-2-Sulfatase, Blood Spot
Supporting the biochemical diagnosis of mucopolysaccharidosis II (MPS II; Hunter syndrome) This test is not useful for determining carrier status for MPS II.
ARSBB - Overview: Arylsulfatase B, Blood Spot
Supporting the biochemical diagnosis of mucopolysaccharidosis type VI (MPS VI, Maroteaux-Lamy syndrome) This test is not useful for carrier detection for MPS VI
CALX - Overview: CALR Mutation Analysis, Myeloproliferative Neoplasm (MPN), Reflex, Varies
Aiding in the distinction between a reactive cytosis and a chronic myeloproliferative disorder Evaluating mutations in CALR in an algorithmic process for the MPNR / Myeloproliferative Neoplasm, JAK2 V617F with Reflex to CALR and MPL,...
10_IS - Overview: Factor X Inhibitor Screen, Plasma
Detecting the presence of a specific factor inhibitor directed against coagulation factor X
F7_IS - Overview: Factor VII Inhibitor Screen, Plasma
Detecting the presence of a specific factor inhibitor directed against coagulation factor VII
F2_IS - Overview: Factor II Inhibitor Screen, Plasma
Detecting the presence of a specific factor inhibitor directed against coagulation factor II
11_IS - Overview: Factor XI Inhibitor Screen, Plasma
Detecting the presence of a specific factor inhibitor directed against coagulation factor XI
ADALX - Overview: Adalimumab Quantitative with Reflex to Antibody, Serum
Therapeutic drug monitoring of adalimumab concentration and antibody levels, if appropriate
MPS4B - Overview: Mucopolysaccharidosis IV Enzyme Panel, Blood Spot
Supporting the biochemical diagnosis of mucopolysaccharidosis type IVA and IVB This test is not useful for carrier detection.
F5_IS - Overview: Factor V Inhibitor Screen, Plasma
Detecting the presence of a specific factor inhibitor directed against coagulation factor V
CL_F - Overview: Chloride, Feces
Workup of cases of chronic diarrhea Evaluation of suspected chloridorrhea
F9_IS - Overview: Factor IX Inhibitor Screen, Plasma
Detecting the presence of a specific factor inhibitor directed against coagulation factor IX
IGFB3 - Overview: Insulin-Like Growth Factor-Binding Protein 3, Serum
Diagnosing growth disorders Diagnosing adult growth hormone deficiency Monitoring of recombinant human growth hormone treatment As a possible adjunct to insulin-like growth factor 1 and growth hormone in the diagnosis and follow-up of...
ECMP - Overview: Eculizumab Monitoring Panel, Serum
Monitoring of complement blockage by eculizumab Assessing the response to eculizumab therapy Assessing the need for dose escalation Evaluating the potential for dose de-escalation or discontinuation of therapy in remission...
DGGL - Overview: Gliadin (Deamidated) Antibody, IgG, Serum
Assessment of deaminated gliadin IgG antibodies for evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family...
INFXR - Overview: Infliximab Quantitation with Reflex to Antibodies to Infliximab, Serum
Trough level quantitation for evaluation of patients undergoing therapy with infliximab, with signs and symptoms of loss of response to therapy.
ALDEF - Overview: Alpha Defensin, Lateral Flow Assay, Synovial Fluid
Detection of alpha defensins 1-3, human host response proteins, in synovial fluid of adults with a total joint replacement who are being evaluated for revision surgery This test is not intended to be used to determine timing for...
DGLDN - Overview: Gliadin (Deamidated) Antibodies Evaluation, IgG and IgA, Serum
Assessment of deaminated gliadin IgA and IgG antibodies for evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk...
DAGL - Overview: Gliadin (Deamidated) Antibody, IgA, Serum
Assessment of deaminated gliadin IgA antibodies for evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family...
TSTGP - Overview: Tissue Transglutaminase Antibodies, IgA and IgG Profile, Serum
Evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disease,...
TTGA - Overview: Tissue Transglutaminase Antibody, IgA, Serum
Assessment of tissue transglutaminase IgA antibodies for evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk...
FBILM - Overview: Biliary Tract Malignancy-Cytology, FISH, Varies
Assessing bile duct brushing or hepatobiliary brushing specimens for bile tract malignancy
BILAO - Overview: Biliary Tract Malignancy, FISH, Varies
Assessing bile duct brushing or hepatobiliary brushing specimens for biliary tract malignancy
MP8BS - Overview: Mucopolysaccharidoses, Eight-Enzyme Panel, Blood Spot
Supporting the biochemical diagnosis of mucopolysaccharidoses types II, IIIA, IIIB, IIIC, IVA, IVB, VI, and VII, and of multiple sulfatase deficiency This test is not useful for carrier detection.
ABADL - Overview: Adalimumab Antibody, Serum
Therapeutic drug monitoring of adalimumab antibody levels
QNADL - Overview: Adalimumab Quantitative, Serum
Therapeutic drug monitoring of adalimumab concentration
ALAUR - Overview: Aminolevulinic Acid, Urine
Assisting in the differential diagnosis of the acute hepatic porphyrias
Information: Interpreting Laboratory Tests to Determine New vs. Residual Use of Marijuana - Insights
In this month's "Hot Topic," Paul Jannetto, Ph.D., identifies how to determine new vs. residual use of marijuana in a patient, and teaches how to calculate the carboxy-tetrahydrocannabinol (carboxy-THC)...
Laboratory and Pathology Research Roundup: March 12 - Insights
known. We performed laser microdissection (LCM) of glomeruli followed by mass spectrometry (MS) in 12 cases each of DDD, C3GN, and pretransplant kidney control biopsies....
COVID-19: At-home sample collection vs. at-home testing - Insights
The concept of at-home testing for COVID-19 sounds straightforward. But there's nuance to it that's important to understand. Right now, an at-home test for COVID-19 is not available, although there may be one coming soon. But in some areas,...
Clinic Laboratory and Pathology Research Roundup: Nov. 12 - Insights
This week’s Research Roundup highlights a mechanism for preventing asymmetric histone segregation onto replicating DNA strands.
Transfusion Toons: A1 vs. A2 - Insights
Justin Kreuter, M.D., Clinical Pathologist and Medical Director of the Mayo Clinic Blood Donor Center in Rochester, Minnesota, and Theresa Malin, an Education Specialist in Transfusion Medicine at Mayo Clinic, have launched “Transfusion...