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Leslie Donato, Ph.D., Discusses New Lab Testing Options to Evaluate IBS-D Patients - Insights
Leslie Donato, Ph.D., Consultant in Cardiovascular Laboratory Medicine and Clinical Core Laboratory at Mayo Clinic, recently authored an article in "Medical Lab Management" on new laboratory testing options to evaluate irritable bowel...
Mayo Clinic physicians and scientists drive research and test development, and our assays are backed by some of the world’s leading subspecialists.
Ganglioside-associated neuropathies - Insights
Learn how Mayo Clinic Laboratories’ ganglioside antibody evaluation can provide diagnostic clarity and a path forward for patients impacted by autoimmune peripheral neuropathy.
Check out Mayo Clinic Laboratories’ biochemical and molecular testing options to diagnose creatine deficiency disorders.
Using Statin Choice Decision-Aid Tool and Laboratory Testing to Reduce Cardiac Risk - Insights
With more than 70,000 uses worldwide and policy endorsements for its use (JAMA Article), the Mayo Clinic Statin Choice Decision-Aid tool is helping patients and their clinicians have meaningful conversations about whether or not to use...
The Latest on Measles: Matthew Binnicker, Ph.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by Matthew Binnicker, Ph.D., director of the Clinical Virology Laboratory at Mayo...
Tick Season Outlook: Elitza Theel, Ph.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, to...
Pathways Case Studies: June 2022 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for June include the following sub-specialties: Dermatopathology, Gastroenterology...
Calprotectin and Inflammatory Bowel Disease - Insights
The differential diagnosis for inflammatory bowel disease (IBD) includes irritable bowel syndrome (IBS). While the clinical presentation is similar, IBD is an inflammatory disease, while IBS is a noninflammatory disease. View this "Hot...
Optic Neuritis in the Era of Biomarkers - Insights
Antibodies to aquaporin-4 and myelin oligodendrocyte glycoprotein (MOG) are recently described biomarkers seen in a subset of atypical optic neuritis which have revolutionized our understanding of the condition. In this “Hot Topic,” my...
infectious_endocarditis_diagnostic_testing_for_identification_of_microbiological_etiology.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 08/2023 This algorithm is intended for use in patients with clinical and/or echocardiographic findings suggestive of infective endocarditis, based on the...
CPT codes and LOINC update: January 2021 - Insights
The following list includes updates posted to mayocliniclabs.com during the month of January.
Mayo Clinic Laboratory and Pathology Research Roundup: July 10 - Insights
This week’s Research Roundup highlights the association of postoperative high-sensitivity troponin levels with myocardial injury and 30-day mortality among patients undergoing noncardiac surgery.
May 2023 - Renal Pathology - Insights
This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Renal Pathology.
June 2023 - Gynecologic Pathology - Insights
This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Gynecological Pathology.
Autoimmune GI Dysmotility - Mayo Clinic Laboratories
Identifying GI dysmotility as autoimmune-mediated is extremely important because patients treated with immunotherapy can see a dramatic improvement, going from persistent nausea, vomiting, and weight loss to feeling normal within a few...
Education on this topic decreases misdiagnosis and the possibility of misinterpreting the comments provided by the reporting laboratories.
Mayo Clinic Laboratory and pathology research roundup: April 11 - Insights
This week's Research Roundup feature: A stress-induced cilium-to-PML-NB route drives senescence initiation.
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) calculator - Insights
For guidance on when to use the calculator, please see the following algorithm: Acquired Neuropathy Diagnostic Algorithm.
Mayo Clinic Laboratory and pathology research roundup: August 22 - Insights
This week's research roundup feature: Association of plasma biomarkers of Alzheimer Disease with cognition and medical comorbidities in a biracial cohort.
Mayo Clinic Laboratory and pathology research roundup: August 15 - Insights
This week's research roundup feature: Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis.
Lab discoveries fuel updates for autoimmune movement disorders test - Insights
Mayo Clinic Laboratories expanded movement disorders panel better identifies autoimmune conditions. Four recently identified biomarkers — septin-5, septin-7, neurochondrin, and adaptor protein-3B2 — have been added to the panel, and all...
hereditary_peripheral_neuropathies_testing_algorithm.pdf
Inherited neuropathy suspected; Insidious onsets progressive (years)* The following tests should be performed in all adult patients: HbA1c or glucose tolerance, vitamin B12, monoclonal proteins. Order PMPDD / PMP22 Gene, Large Deletion...
Inflammatory bowel disease - Insights
Our robust menu of inflammatory bowel disease (IBD) testing can assist with the diagnosis and management of IBD and includes first-line fecal testing for calprotectin; serologic analysis of clinically relevant antibodies; and genetic...
Antibody Prevalence in Epilepsy and Encephalopathy (APE2 ) score - Insights
Antibody Prevalence in Epilepsy and Encephalopathy (APE2 ) score.
Precision mental and behavioral health therapeutics - Insights
Our Precision Mental and Behavioral Health Therapeutics initiative leverages cutting-edge diagnostic solutions to optimize medication management for psychiatric and neurologic patients.
Explore how Mayo Clinic Laboratories’ focused myositis specific antibody (MSA) panel equips healthcare professionals with individualized insights to reduce diagnostic uncertainty and assist with the selection of tailored treatments for...
Serotonin release assay - Insights
Find out more about our serotonin release assay, the gold standard diagnostic test for detecting heparin-induced thrombocytopenia antibodies.
Mayo Clinic Laboratory and Pathology Research Roundup: January 23 - Insights
This week's research roundup feature: Measles virus (MV) vaccine strains have shown significant preclinical antitumor activity against glioblastoma (GBM), the most lethal glioma histology. In this first in human trial (NCT00390299), a...
Mayo Clinic Laboratory and Pathology Research Roundup: Dec. 25 - Insights
This week’s Research Roundup highlights global pulmonary vascular remodeling in pulmonary hypertension associated with heart failure and preserved or reduced ejection fraction.
Autoimmune Dementia Testing - Mayo Clinic Laboratories
Our phenotype specific testing for autoimmune dementia contains only clinically relevant antibodies providing accurate answers for treatment guidance.
Axonal autoimmune neuropathies - Insights
Find out about our panel-based approach to axonal autoimmune neuropathies, which we recommend because of the overlap in clinical symptoms.
Mayo Clinic has launched a first-in-the-U.S. clinical test that will help patients who recently have been diagnosed with an inflammatory demyelinating disease but may be unsure of the exact disorder.
In this “Hot Topic,” Elitza Theel, Ph.D., discusses how common cases of presumed Lyme disease go unreported each year and discusses scenarios in which testing for Lyme disease is indicated and reviews both recommended and inappropriate...
IGHV and TP53 Sequencing: Clinical Utility in Chronic Lymphocytic Leukemia (CLL) - Insights
In this month’s “Hot Topic,” Curtis Hanson, M.D., will discuss the use of laboratory-based prognostic markers in patients with chronic lymphocytic leukemia (CLL). He will also highlight the importance of molecular analyses for IGHV and TP53...
JoAnne Michael’s symptoms started with dizziness and forgetfulness before down spiraling into severe confusion, crying jags, and brain seizures. ER doctors at her local hospital initially thought she was on drugs. JoAnne, terrified,...
Patient Information and Signature Forms - Mayo Clinic Laboratories
Test Catalog AlgorithmsDownload Test Catalog & Interpretive HandbookNew TestsNY State Informed Consent TestsPerforming LocationsReferred TestsSpecialty TestingTest Updates...
Mayo Clinic Laboratories’ BioPharma Diagnostics team facilitates customized collaborations with diagnostic companies to support their clinical and research testing needs.
Assay stratifies pregnant women's preeclampsia risk: Joshua Bornhorst, Ph.D. - Insights
Joshua Bornhorst, Ph.D., explains how Mayo Clinic Laboratories' unique assay identifies pregnant women at risk of developing preeclampsia with severe features. Test results can guide clinical management, to safeguard maternal and neonatal...
Mayo Clinic Laboratory and pathology research roundup: September 26 - Insights
This week's research roundup feature: Semaglutide in HFpEF across obesity class and by body weight reduction.
New tests launched in November - Insights
In November 2022, Mayo Clinic Laboratories announced eighteen new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Assay enhances and simplifies M-proteins screening: David Murray, M.D., Ph.D. - Insights
David Murray, M.D., Ph.D., explains how Mayo Clinic Laboratories' MASSFIX Quantitation assay provides next-generation screening for M-proteins, which are associated with multiple myeloma and other diseases. The assay better quantitates the...
John Mills, Ph.D., and Divyanshu Dubey, M.B.B.S., explain how Mayo Clinic Laboratories' new test panel can distinguish among various potential causes of demyelinating neuropathies. Test results are important for managing these devastating...
Patient Information and Signature Forms - Mayo Clinic Laboratories
Test Catalog AlgorithmsDownload Test Catalog & Interpretive HandbookNew TestsNY State Informed Consent TestsPerforming LocationsReferred TestsSpecialty TestingTest Updates...
Mayo Clinic Laboratory and Pathology Research Roundup: March 12 - Insights
This week's research roundup feature: C3 glomerulopathy (C3G) is a rare disease resulting from dysregulation of the alternative pathway of complement. C3G includes C3 glomerulonephritis (C3GN) and dense deposit disease (DDD), both of which...
Learn more about how Mayo Clinic Laboratories’ targeted, high-resolution screening panel for stimulant use identifies and confirms the presence of 10 stimulants and phencyclidine (PCP) with a single test.
Mayo Clinic Laboratory and Pathology Research Roundup: December 12 - Insights
This week's research roundup feature: Most patients with solitary bone plasmacytomas (SBP) progress to multiple myeloma (MM) after definitive radiation therapy as their primary treatment. Whether the presence of high-risk (HR) cytogenetic...
Antibody against the GABA-A receptor is a biomarker of autoimmune encephalopathy that occurs across the lifespan, and disproportionately affects children. In this test-specific episode of the "Answers From the Lab" podcast, Andrew McKeon,...
Maria Alice Willrich, Ph.D., and Melissa Snyder, Ph.D., explain how Mayo Clinic Laboratories' unique risankizumab panel measures levels of both that drug and its antibodies in patients' blood. The results can better guide the management of...