Raising the Bar on Newborn Screening Test Performance - Insights
Newborn screening panels that test for a variety of conditions are available in every state; however, test performance and response rate by each state are very different. Mayo Clinic's Biochemical Genetics Laboratory created the...
Cardiovascular Biomarkers of Atherosclerotic Risk - Insights
In this month’s “Hot Topic,” Vlad Vasile, M.D., Ph.D., reviews ceramides and their atherosclerotic risk through defining ceramides, talking about when they should be tested for and touch on the topic of ceramides in primary prevention.
Pathways Case Studies: March 2022 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for March include the following sub-specialties: Breast Pathology, Cardiovascular...
Innovative Alzheimer's disease diagnostic tool unveiled - Insights
Mayo Clinic Laboratories has marked a significant advancement in the fight against Alzheimer's disease with the introduction of an innovative diagnostic test. This noninvasive blood test accurately detects the p-Tau217 biomarker, indicative...
Patients with Blood Cancer Precursor at Risk of Developing Cancer Even after 30 Years - Insights
Patients with monoclonal gammopathy of undetermined significance are at risk of progressing to multiple myeloma or a related cancer─even after 30 years of stability, according to findings of a study by Mayo Clinic researchers published in...
Frontotemporal dementia and ALS - Insights
Learn more about how detection of amyotrophic lateral sclerosis and frontotemporal dementia paved the way for gene-targeted therapies for patients.
Pathways Case Studies: September 2023 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for September include the following sub-specialties: Cardiovascular Pathology,...
Autoimmune Epilepsy Testing - Mayo Clinic Laboratories
Our phenotype specific testing for autoimmune epilepsy contains only clinically relevant antibodies providing accurate answers for treatment guidance.
hereditary_peripheral_neuropathies_testing_algorithm.pdf
Inherited neuropathy suspected; Insidious onsets progressive (years)* The following tests should be performed in all adult patients: HbA1c or glucose tolerance, vitamin B12, monoclonal proteins. Order PMPDD / PMP22 Gene, Large Deletion...
Find out how our pediatric oncology testing was designed to deliver individualized insights to confirm diagnosis and guide treatment.
Addiction rehabilitation monitoring - Insights
Encompassing comprehensive profiles, confirmatory testing, and interpretive results reporting, addiction rehabilitation monitoring at Mayo Clinic Laboratories supports patients affected by substance use disorder in their rehabilitation and...
CPT codes and LOINC update: November 2022 - Insights
This list includes updates posted to mayocliniclabs.com during the month of November.
In this month’s “Hot Topic,” Robin Patel, M.D., discusses how matrix-assisted laser desorption ionization time of flight (MALDI TOF) mass spectrometry works for bacterial identification, including the strengths and limitations of this...
April 2023 - Cellular Therapy and Transfusion Medicine - Insights
This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case’s sub-specialties are Cellular Therapy and Transfusion Medicine.
Week in Review: May 27 - Insights
Today's highlights include: Long COVID affects more older adults, US has a new dominant COVID-19 strain, and Gianrico Farrugia explains how we can transform healthcare by moving from pipeline to platform.
Manage to Reimbursement - Insights
PACE/State of FL This webinar will provide a methodology for laboratory leadership to review their test menu for assays that most impact the financial health of their laboratory.
Find out how our hereditary cancer panels use next-generation sequencing to evaluate dozens of genes associated with cancer risk.
Dementia with Lewy bodies, Parkinson's, and multiple system atrophy - Insights
Learn more about how Mayo Clinic Laboratories' cerebrospinal fluid biomarker test for synucleinopathies, such as Parkinson’s disease and dementia with Lewy bodies, can accurately identify α-syn pathology even before definitive symptoms...
Staffing to Workload: Direct Effort - Insights
Mike Baisch, Systems Engineer at Mayo Clinic, discusses the mechanics of performing a staffing-to-workload analysis in the testing laboratories. There are three primary areas of focus with staffing needs: direct effort, indirect effort, and...
In a recent issue of Mayo Clinic's Digestive Diseases, Michael Camilleri, M.D., a gastroenterologist at Mayo Clinic, and Leslie Donato, Ph.D., Co-Director for Cardiovascular Laboratory Medicine, Hospital Clinical Laboratory, and Point of...
Mayo Clinic Laboratory and Pathology Research Roundup: April 16 - Insights
This week’s Research Roundup highlights the clinical and pathological phenotype of genetic causes of focal segmental glomerulosclerosis in adults.
Pathways Case Studies: April 2020 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for April include the following sub-specialties: Gastroenterology & Surgical,...
Monogenic IBD Testing - Mayo Clinic Laboratories
Monogenic inflammatory bowel disease (IBD) refers to a diverse spectrum of rare genetic disorders that present with intestinal inflammation. The majority of patients with monogenic IBD, unlike those with polygenic IBD, show symptoms before...
Assay provides quick diagnosis of VEXAS syndrome: David S. Viswanatha, M.D. - Insights
David S. Viswanatha, M.D., explains how Mayo Clinic Laboratories' new assay provides rapid, definitive diagnosis of VEXAS, a recently identified syndrome affecting older men. Early diagnosis is key to managing the syndrome, which severely...
PD-L1 Testing by Immunohistochemistry - Insights
In this month's "Hot Topic," Anja Roden, M.D., discusses the role of PD-L1 interaction in the immune system, challenges of PD-L1 testing, and current PD-L1 companion testing in various tumor types.
In this month’s “Hot Topic,” Paul Jannetto, Ph.D., discusses the high-resolution targeted opioid screening test from Mayo Clinic Laboratories, which offers sensitivity and specificity for use in the monitoring and management of patients who...
Ann Moyer, M.D., Ph.D., Makes a Case for Pharmacogenomics - Insights
Pharmacogenomic testing is still limited, despite ample research, the existence of guidelines, and the emerging evidence it can help patients. Ann Moyer, M.D., Ph.D., Co-Director of the Personalized Genomics Laboratory at Mayo Clinic in...
One Test, Multiple Targets: Zeroing in on Autoimmune Movement Disorders - Insights
A movement disorder might be caused by the body’s immune system, which is meant to fight infections, suddenly attacking the brain. Fortunately, an “autoimmune movement disorder” can often be treated—once its cause is discovered.
Respiratory viruses - Insights
Browse our full suite of serology and PCR testing for respiratory viruses like influenza, RSV, and more.
Elevating accuracy of Alzheimer's testing - Insights
Learn how Mayo Clinic Laboratories Alzheimer’s disease testing provides clearer answers for more patients by offering the highest level of overall accuracy for the detection of amyloid pathology.
Present Approaches to Testing - Insights
Discussing current test applications that you can implement in your laboratory or practice today.
Is the term "outreach" obsolete? - Insights
In a competitive outpatient testing market, choosing a laboratory is discretionary. With the goal of becoming the laboratory of choice for discretionary outpatient testing, it no longer matters if it is called “inreach” or “outreach.” While...
Wei Shen, Ph.D., and Rhianna Urban, M.S., CGC, explain how Mayo Clinic Laboratories' gene panel establishes a diagnosis of Lynch syndrome, which heightens the risk for several cancers. Test results can guide targeted cancer surveillance for...
Kootenai Health: Recapturing their market through precision coordination - Insights
Prevented from providing testing services to its community members due to a non-compete agreement with a national laboratory, Kootenai Health laboratory leaders deepened their relationship with Mayo Clinic Laboratories, receiving tactical...
Cytomegalovirus, or CMV, is a common cause of disease in the transplant population. In some patients who are diagnosed with CMV and are on antiviral treatment for infections, the virus may develop resistance to the drugs. This “Hot Topic”...
Whole exome sequencing - Insights
Learn more about how whole exome sequencing at Mayo Clinic Laboratories can quickly end diagnostic testing odysseys for patients with suspected genetic disorders.
Pathways Case Studies: January 2023 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for January include the following sub-specialties: Bone and Soft Tissue Pathology,...
MCL Whole Exome Sequencing Advanced Understanding of Genetic Disease Flyer MC2775523
MCL Exome Sequencing Advanced Understanding Genetic Disease Flyer EXOME SEQUENCING ADVANCED UNDERSTANDING GENETIC DISEASE millions individuals affected rare diseases 80
The evolution of specimen accessioning and delivery - Insights
The last installment of our 50th Anniversary series explores how Mayo Clinic Laboratories pioneered best practices in the area of specimen accessioning and delivery.
MCL @Work: Jessica Balcom - Insights
In 2010, Jessica Balcom began her career with Mayo Clinic supporting molecular testing in the Department of Laboratory Medicine and Pathology with a joint appointment in the Mayo Clinic Cystic Fibrosis Center. Now she serves as a...
Mayo Clinic Staff Members Honored in ASCP's "40 under Forty" - Insights
The American Society for Clinical Pathology (ASCP) has announced the 2017 “40 under Forty” honorees. Each year, the Selection Committee identifies 40 ASCP members under the age of 40 who are recognized for being future pathology and...
Communiqué takes a deep dive into how Mayo Clinic Laboratories advances patient care, research, and education through laboratory medicine. Our experts are solving the most serious and complex medical challenges for patients worldwide.
Frequently asked questions - Insights
Check out how chromosomal microarray testing at Mayo Clinic Laboratories can help optimize treatment for neurological tumors.
Neuro-Oncology Testing - Mayo Clinic Laboratories
At Mayo Clinic, we offer a comprehensive approach to neuro-oncology testing that focuses on the best outcomes for the patient
Hereditary Alzheimer's disease and dementia - Insights
Learn about our genetic testing for Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), frontotemporal dementia, and CADASIL.
The following on demand education is related to the “Other” category in medical laboratory science (MLS), which encompasses a variety of specialized topics and emerging areas that don’t fall into traditional categories like hematology,...
The Region 4 Stork (R4S) Collaborative Project - Insights
This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.
A novel testing approach for newly identified VEXAS syndrome - Insights
VEXAS syndrome is a severe autoinflammatory disease that results in a spectrum of rheumatologic and hematologic conditions. The underlying cause of newly identified VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome —...
The Region 4 Stork (R4S) Collaborative Project - Insights
This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.
The Region 4 Stork (R4S) Collaborative Project - Insights
This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.