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Mayo Clinic Laboratory and pathology research roundup: August 22 - Insights
This week's research roundup feature: Association of plasma biomarkers of Alzheimer Disease with cognition and medical comorbidities in a biracial cohort.
Mayo Clinic Laboratory and pathology research roundup: August 15 - Insights
This week's research roundup feature: Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis.
Autoimmune Encephalitis Diagnosis and Misdiagnosis - Insights
PACEIn this month’s “Virtual Lecture” Eoin Flanagan, M.D., B.Ch., reviews how to diagnose autoimmune encephalitis, what to watch that may suggest a different diagnosis, discuss neural autoantibodies interpretation and putting test results...
Early-Onset IBD: Genetic Testing and Clinical Applications - Insights
Identification of early-onset IBD patients may enable tailored treatment and surveillance plans. With over 50 genes implicated in early-onset IBD, genetic testing should be included in the workup of children under the age of six with IBD....
Mayo Clinic Laboratory and pathology research roundup: April 11 - Insights
This week's Research Roundup feature: A stress-induced cilium-to-PML-NB route drives senescence initiation.
Testing Options for Patients with Chronic Diarrhea: A Focus on Bile Acid Malabsorption - Insights
A new serum test for bile acid malabsorption. Descriptions illustrate how the test can be used as a screening test and as a tool for therapeutic action.
Six ways innovative lupus tests are transforming patient and clinician experiences - Insights
widely used laboratory tests for patients with this complex condition were developed more than 60 years ago, and physicians need modern, evidence-based tools to provide high-quality care for their patients...
Infectious diseases - Insights
capabilities of Mayo Clinic’s internationally renowned clinical microbiology laboratories. With more than 70 years of testing experience, our laboratories span all areas of conventional and molecular medical microbiology...
Mayo Clinic Laboratory and Pathology Research Roundup: November 14 - Insights
This week's research roundup feature: Microaggressions between members of a team occur often in medicine, even despite good intentions. Such situations call for difficult conversations that restore inclusivity, diversity, and a healthy work...
Mayo Clinic Laboratory and pathology research roundup: July 4 - Insights
This week's research roundup feature: Emergence of inducible macrolide resistance in mycobacterium chelonae due to broad-host-range plasmid and chromosomal variants of the novel 23S rRNA methylase gene, erm(55).
Advancing our Understanding of Immunoglobulins to Better Understand Disease - Insights
PACE / State of FLIn this month’s “Virtual Lecture,” David Murray, M.D., Ph.D., discusses how immunoglobin light chains are used to detect overexpressed immunoglobins which can be applied to distinguish patients with plasma cell disorders...
2017 Mayo Medical Laboratories Lab Week Door Winner - Insights
“All-Stars Laboratory Team: Teaming up for Patient Care.” We ended up with 20 door submissions this year, which made for a very close competition. There are SO many creative staff members at Mayo Medical...
Mayo Clinic Minute: The ABCs of Avoiding Ticks - Insights
snow melts, ticks start coming up from under the grass looking for a "blood meal." She says that this year, after a relatively mild winter, ticks got an early start. This means that tick season could be particularly...
Classification of Kidney Stone Composition Using an AI Model - Insights
PACE / State of FLThis month’s “Virtual Lecture,” discusses how artificial intelligence can be utilized to classify kidney stones while demonstrating improvement in quality and patient safety.
Mayo Clinic Laboratory and pathology research roundup: September 19 - Insights
This week's research roundup feature: There is a need to develop safe and effective pharmacologic options for the treatment of celiac disease (CeD); however, consensus on the appropriate design and configuration of randomized controlled...
Mayo Clinic Laboratory and Pathology Research Roundup: October 17 - Insights
This week's research roundup feature: Given the prevalence of dementia and the development of pathology-specific disease modifying therapies, high-value biomarker strategies to inform medical decision making are critical. In-vivo tau...
Mayo Clinic Laboratory and Pathology Research Roundup: October 31 - Insights
This week's research roundup feature: It is widely held that heart failure (HF) does not cause exertional hypoxaemia, based upon studies in HF with reduced ejection fraction, but this may not apply to patients with HF and preserved ejection...
Mayo Clinic Laboratory and Pathology Research Roundup: November 28 - Insights
This week's research roundup feature: Microaggressions between members of a team occur often in medicine, even despite good intentions. Such situations call for difficult conversations that restore inclusivity, diversity, and a healthy work...
Complement Testing in the Diagnosis and Management of Thrombotic Microangiopathy - Insights
PACE / State of FLThis month’s “Virtual Lecture” discusses the clinical diagnosis and management, summarizes the testing modalities that guide diagnosis and management, and recognizes the utility of genetic testing as it relates to...
Mayo Clinic Laboratory and pathology research roundup: June 27 - Insights
This week's research roundup feature: SARS-CoV-2 spike codon mutations and risk of hospitalization after antispike monoclonal antibody therapy in solid organ transplant recipients.
Mayo Clinic Laboratory and pathology research roundup: July 18 - Insights
This week's research roundup feature: Natural history, predictors of development of extramedullary disease, and treatment outcomes for patients with extramedullary multiple myeloma.
Mayo Clinic Laboratory and pathology research roundup: August 1 - Insights
This week's research roundup feature: A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling.
PACE / State of FLThis month’s “Virtual Lecture” recognizes the importance of tracking tumor cell development and the heterogeneity in cancer cell growth dynamics at the clonal resolution and reveals features of tumor cell metastasis.
Anti-Platelet Factor 4 Antibody-Mediated Prothrombotic Syndromes - Insights
PACE / State of FLIn this month's "Virtual Lecture," Anand Padmanabhan provides a general overview and science in the field related to heparin-induced thrombocytopenia (HIT), vaccine-induced thrombotic thrombocytopenia (VITT), and...
PACE/State of FL - This "Phlebotomy Webinar" will review proper blood culture collection techniques and demonstrate how specimen quality can impact patient care.
Accurate Kidney Stone Analysis - Insights
In this “Hot Topic,” Paul Jannetto, Ph.D., highlights Mayo Clinic Laboratories’ AI-augmented kidney stone test and discusses the proper procedures for collecting and processing kidney stones to provide accurate, cost-effective analysis of...
Mayo Clinic Laboratory and pathology research roundup: October 3 - Insights
This week's research roundup feature: Gene fusions involving tumor protein p63 gene (TP63) occur in multiple T and B cell lymphomas and portend a dismal prognosis for patients. The function and mechanisms of TP63 fusions remain unclear, and...
Mayo Clinic Laboratory and pathology research roundup: September 26 - Insights
This week's research roundup feature: Semaglutide in HFpEF across obesity class and by body weight reduction.
Hurricane Lee: Potential specimen delays - Insights
Hurricane Lee will be impacting the New England area and northeastern Canada this weekend. We are monitoring and tracking the situation with our logistics partners to minimize challenges. Your organization will be contacted directly by the...
What's New in Quality and Regulatory Expectations for Laboratories? [2022] - Insights
regulatory issues that have the potential to affect clinical laboratories. The latter half of the year has been very busy for laboratory-related regulations and legislation, including the potential VALID...
Dr. Robin Patel shares periprosthetic joint infection findings in NEJM - Insights
The New England Journal of Medicine recently published new findings on periprosthetic joint infection by Dr. Robin Patel.
Neuropathy and Neuromuscular Gene Panel Update - Insights
In this month's "Hot Topic," Christopher Klein, M.D., and Zhiyv (Neal) Niu, Ph.D., discuss how Mayo Clinic’s neuropathy and neuromuscular gene panels have enhanced patient care.
Unveiling a novel hemoglobinopathy classification - Insights
In a recent discovery by Mayo Clinic Laboratories, a novel hemoglobinopathy category was identified and termed epsilon gamma thalassemia. The first instance of the disorder was found in 2017 when an obstetric patient underwent a routine...
Testing for Antibodies to SS-A/Ro in Autoimmune Diseases - Insights
In this month’s “Hot Topic,” Anne Tebo, Ph.D., discusses recent updates in the testing for anti-SS-A/Ro antibodies in systemic autoimmune rheumatic diseases.
Mayo Clinic Laboratory and Pathology Research Roundup: December 12 - Insights
This week's research roundup feature: Most patients with solitary bone plasmacytomas (SBP) progress to multiple myeloma (MM) after definitive radiation therapy as their primary treatment. Whether the presence of high-risk (HR) cytogenetic...
Mayo Clinic Laboratories, a leading reference laboratory, and Helix, the nation’s leading population genomics and viral surveillance company, today announced a new strategic collaboration that will provide life sciences customers access to...
Mayo Clinic Laboratory and Pathology Research Roundup: December 26 - Insights
This week's research roundup feature: Histoplasma and Blastomyces antigen detection assays are commonly used diagnostic tools. However, a high level of cross-reactivity between these antigens prevents definitive pathogen identification by...
Staffing to Workload - Insights
PACE / State of FLThis Continual Improvement webinar will focus on a data driven and systematic approach to understand demand, identify idle time, and optimize work schedules. We will examine the different variations that exist when...
Dr. Matt Binnicker sheds light on new Arcturus COVID-19 variant - Insights
Matthew Binnicker, Ph.D., director of Mayo Clinic’s Clinical Virology Laboratory, provides insight on the newest COVID-19 subvariant – XBB.1.16, also known as “Arcturus.”
Why laboratory professionals should embrace the spotlight during Lab Week - Insights
On this episode of Mayo Clinic Laboratories’ “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager, returns with outreach solutions strategists Ellen Dijkman Dulkes and Brianne Newton to chat about National Medical...
Best practices for managing outreach supplies - Insights
In this episode of Mayo Clinic Laboratories “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, talks with outreach solutions strategists Ellen Dijkman Dulkes and Brianne Newton about...
KPIs: If you can't measure it, you can't manage it - Insights
In this episode of Mayo Clinic Laboratories’ “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, talks with outreach solutions strategists Ellen Dijkman Dulkes and Brianne Newton about key...
Diagnostic Guidelines for Celiac Disease - Insights
In this "Hot Topic," Melissa Snyder, Ph.D., provides a brief review of published guidelines for the diagnosis of celiac disease, with a specific focus on the role of laboratory testing.
Database of unsolved patient sequencing results yields new answers - Insights
Mayo Clinic launched an automated system called RENEW — reanalysis of negative whole-exome/genome data — in 2022 that tracks newly published discoveries of disease-causing genetic variants. Every three months, the system automatically...
Applying Mayo Clinic MASSFIX to Urine Samples - Insights
In this month's "Hot Topic," David Murray, M.D., Ph.D., reviews the role of urine testing for monoclonal gammopathies and discusses Mayo Clinic’s use of MASSFIX to replace traditional immunofixation testing.
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High-Resolution Targeted Benzodiazepine Screen - Insights
In this “Hot Topic,” Paul Jannetto, Ph.D., highlights Mayo Clinic’s targeted benzodiazepine assay and discusses the advantages and limitations of various urine-screening assays as well as quantitative confirmatory testing to determine...
What Every Pathologist Needs to Know About the Legal System - Insights
In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., sits down with R. Ross Reichard, M.D., a forensic pathologist at Mayo Clinic and associate professor of laboratory medicine and pathology, to discuss what every pathologist...
Mayo Clinic Laboratories presents the 18th Bleeding and Thrombosing Diseases conference - Insights
This conference will provide reviews and updates about the laboratory and clinical aspects of bleeding and thrombosing disorders. Informational presentations will be supplemented with panel discussions and case presentations, followed by...