PD-L1 Testing by Immunohistochemistry - Insights
In this month's "Hot Topic," Anja Roden, M.D., discusses the role of PD-L1 interaction in the immune system, challenges of PD-L1 testing, and current PD-L1 companion testing in various tumor types.
In this month’s “Hot Topic,” Robin Patel, M.D., discusses how matrix-assisted laser desorption ionization time of flight (MALDI TOF) mass spectrometry works for bacterial identification, including the strengths and limitations of this...
Lyme Disease, Part 2: Borrelia mayonii-A New Cause of Lyme Disease in Upper Midwest - Insights
In this “Hot Topic,” Bobbi Pritt, M.D., discusses how Lyme disease is the most common vector-borne illness in the United States and Europe and caused primarily by Borrelia burgdorferi in the United States, while B burgdorferi, B afzelii,...
New tests launched in November - Insights
In November 2021, Mayo Clinic Laboratories announced thirty four new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Pathways Case Studies: March 2023 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for March include the following sub-specialties: Breast Pathology, Cytopathology,...
In this “Hot Topic,” Elitza Theel, Ph.D., discusses how common cases of presumed Lyme disease go unreported each year and discusses scenarios in which testing for Lyme disease is indicated and reviews both recommended and inappropriate...
Membranoproliferative glomerulonephritis (MPGN) is a pattern of glomerular injury. Based on the etiology of MPGN, Drs. Sethi and Fervenza proposed a new histologic classification of MPGN into Ig/IC-mediated MPGN and complement-mediated...
New tests launched in December - Insights
In December 2022, Mayo Clinic Laboratories announced seventy-eight new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Pleural Mesothelioma - Insights
In this month's "Hot Topic," Anja Roden, M.D., a thoracic pathologist at Mayo Clinic, gives an update on the 2021 World Health Organization (WHO) classification and ancillary testing of pleural mesothelioma.
Antifungal Drug Susceptibility Testing of Yeast: A Primer for Beginners - Insights
In this month’s “Hot Topic,” Nancy Wengenack, Ph.D., discusses susceptibility testing of yeast for those who are considering performing it in their laboratory, perhaps for the first time, or for those who choose to send their yeast isolates...