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Each day, some 40 to 45 thousand specimens are shipped to Mayo Clinic Laboratories in Rochester, Minnesota, from hospitals and other health care organizations around the world. And for every sample, there’s a patient to whom it belongs,...
Unveiling a novel hemoglobinopathy classification - Insights
In a recent discovery by Mayo Clinic Laboratories, a novel hemoglobinopathy category was identified and termed epsilon gamma thalassemia. The first instance of the disorder was found in 2017 when an obstetric patient underwent a routine...
October 2023 - Clinical Microbiology - Insights
This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Microbiology.
Discontinuation of Herpes Simplex Virus (HSV) IgM Testing - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss the over utilization of IgM serologic testing for herpes simplex virus and the recommendation by multiple agencies, including the CDC and the Infectious Diseases Society of...
High-Resolution Targeted Benzodiazepine Screen - Insights
In this “Hot Topic,” Paul Jannetto, Ph.D., highlights Mayo Clinic’s targeted benzodiazepine assay and discusses the advantages and limitations of various urine-screening assays as well as quantitative confirmatory testing to determine...
Dengue Virus: A Diagnostic Testing Update - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., talks about Mayo Clinic Laboratories’ serologic and molecular testing for the identification of infection with dengue virus. Dengue virus poses a significant public health threat worldwide....
The 10 Types of Attendees You May Find at a Conference - Insights
Heidi Zunker, Education Program Manager, and Melissa Peterson, Education Specialist, at Mayo Medical Laboratories, discuss the 10 types of attendees you may find at a conference.
Applying the Staffing-to-Workload Methodology: Identifying Daily Indirect Effort Needs - Insights
Mike Baisch, Principal Systems Engineer at Mayo Clinic, demonstrates how daily indirect effort tasks contribute to staffing plans and needs in the staffing-to-workload methodology.
Pathways Case Studies: April 2023 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for April include the following sub-specialties: Gynecological Pathology, Pulmonary...
Pathways Case Studies: March 2022 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for March include the following sub-specialties: Breast Pathology, Cardiovascular...
Sarcoma Informative Cases - Insights
Case #1 Case #2 Case #3 Case #4 Case #5 Sarcomas are malignant tumors that arise in the bone and soft tissue. With numerous subtypes of sarcoma that can
A decade-long search for answers ends at Mayo Clinic: Tyler Hart - Insights
After years of misdiagnosis, Tyler Hart found answers at Mayo Clinic, discovering he had NF155-IgG4 autoimmune nodopathy instead of CIDP
Gadolinium-based contrast agents (GBCAs) have revolutionized MRIs by increasing the clinical utility and detection sensitivity of these exams. GBCAs also contain gadolinium, a rare earth metal with unique chemical properties. This article...
Alzheimer's Disease CSF Biomarkers - Insights
In this month's "Hot Topic," Alicia Algeciras, Ph.D., DABCC, and Joshua Bornhorst, Ph.D., DABCC, discuss Alzheimer's disease CSF biomarkers.
PD-L1 Testing by Immunohistochemistry - Insights
In this month's "Hot Topic," Anja Roden, M.D., discusses the role of PD-L1 interaction in the immune system, challenges of PD-L1 testing, and current PD-L1 companion testing in various tumor types.
Lyme Disease, Part 2: Borrelia mayonii-A New Cause of Lyme Disease in Upper Midwest - Insights
In this “Hot Topic,” Bobbi Pritt, M.D., discusses how Lyme disease is the most common vector-borne illness in the United States and Europe and caused primarily by Borrelia burgdorferi in the United States, while B burgdorferi, B afzelii,...
Autoimmune Encephalopathy Testing - Mayo Clinic Laboratories
Our phenotype specific testing for autoimmune encephalopathy contains only clinically relevant antibodies providing accurate answers for treatment guidance.
Chromogenic Factor VIII and IX Assays: Impact on Diagnosis and Management of Hemophilia - Insights
In this month’s “Hot Topic,” Rajiv Pruthi, M.B.B.S., will discuss different types of hemophilia along with their pathologic basis. He will also cover various types of factor assays such as one stage and chromogenic factor assays for...
Autoimmune Encephalopathy Testing - Mayo Clinic Laboratories
Our phenotype specific testing for autoimmune encephalopathy contains only clinically relevant antibodies providing accurate answers for treatment guidance.
In this month's "Hot Topic," Brad Karon, M.D., Ph.D., reviews pediatric venipuncture volumes in this year’s Phlebotomy Top Gun case-based presentation as requested by previous Phlebotomy conference attendees.
MGLE - Overview: Myasthenia Gravis/Lambert-Eaton Myasthenic Syndrome Evaluation, Serum
Confirming the autoimmune basis of a defect in neuromuscular transmission (eg, myasthenia gravis [MG], Lambert-Eaton myasthenic syndrome [LEMS]) Distinguishing LEMS from autoimmune forms of MG Providing a quantitative autoantibody...
MGMR - Overview: Myasthenia Gravis Evaluation with Muscle-Specific Kinase (MuSK) Reflex, Serum
Diagnosing autoimmune myasthenia gravis (MG) in adults and children Distinguishing autoimmune from congenital MG in adults and children or other acquired forms of neuromuscular junction transmission disorders Establishing a quantitative...
Pathways Case Studies: September 2023 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for September include the following sub-specialties: Cardiovascular Pathology,...
https://www.mayocliniclabs.com/test-catalog/loinc-codes.php
Test Order LOINC Values current as of August 2, 2025 Test ID Test Order Name Order LOINC Code LOINC Attributes Method Name 10AIH Factor X Inhibitor Profile, Professional Interpretation 69049-5 Coagulation specialist...
Predictors to Direct Neural Antibody Testing in Autoimmune Encephalitis/Epilepsy - Insights
In this “Hot Topic,” Divyanshu Dubey, M.B.B.S., associate professor of laboratory medicine and pathology and neurology at Mayo Clinic, discusses various clinical and paraclinical features of autoimmune encephalitis, autoimmune seizures, and...
Pathways Case Studies: June 2022 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for June include the following sub-specialties: Dermatopathology, Gastroenterology...