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Mayo Clinic Laboratory and pathology research roundup: October 3 - Insights

This week's research roundup feature: Gene fusions involving tumor protein p63 gene (TP63) occur in multiple T and B cell lymphomas and portend a dismal prognosis for patients. The function and mechanisms of TP63 fusions remain unclear, and...

Mayo Clinic Laboratory and Pathology Research Roundup: May 28 - Insights

This week’s Research Roundup highlights the clinical and pathology findings associated consistently with larger glomerular volume.

Mayo Clinic Laboratory and Pathology Research Roundup: June 12 - Insights

This week’s Research Roundup highlights noninvasive assessment of renal fibrosis with magnetization transfer MR imaging.

Mayo Clinic Laboratory and Pathology Research Roundup: Nov. 26 - Insights

This week’s Research Roundup highlights the effect of inorganic nitrite versus a placebo on exercise capacity among patients with heart failure with preserved ejection fraction.

Mayo Clinic Laboratory and pathology research roundup: September 27 - Insights

This week's research roundup features: Robotics in neurosurgery: current prevalence and future directions

Mayo Clinic Laboratory and pathology research roundup: September 6 - Insights

This week's research roundup features: Outcomes of tricuspid valve repair with artificial neochordae in pediatric and adult patients

Mayo Clinic Laboratory and Pathology Research Roundup: July 24 - Insights

This week’s Research Roundup highlights renal allograft histology at 10 years after transplantation in the tacrolimus era and evidence of pervasive chronic injury.

Mayo Clinic Laboratory and Pathology Research Roundup: May 22 - Insights

This week’s Research Roundup highlights the management of diffuse low-grade gliomas in adults.

Mayo Clinic Laboratory and Pathology Research Roundup: July 3 - Insights

This week’s Research Roundup highlights the comparison of gadolinium concentrations within multiple rat organs after intravenous administration of linear versus macrocyclic gadolinium chelates.

Large Scale Study: Outcomes for Long QT Syndrome Patients Treated at Specialty Center Are Better - Insights

Sudden cardiac death and episodes of fainting and seizures from long QT syndrome are significantly lower than previously thought when patients are diagnosed and treated at a specialty center dedicated to the treatment of genetic heart...

Mayo Clinic Laboratory and Pathology Research Roundup: May 29 - Insights

This week’s Research Roundup highlights the evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers.

Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 28 - Insights

This week’s Research Roundup highlights a review of how to treat autoimmune hemolytic anemia.

Mayo Clinic Laboratory and pathology research roundup: June 28 - Insights

This week’s research roundup features: Understanding "Patient refuses" among 90+ year old patients with cancer or presumed cancer.

Mayo Clinic Laboratory and pathology research roundup: August 2 - Insights

This week's research roundup features: Gastrointestinal stromal tumors mimicking gynecologic disease: clinicopathological analysis of 20 cases.

Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 27 - Insights

This week’s Research Roundup highlights a mechanism for preventing asymmetric histone segregation onto replicating DNA strands.

Mayo Clinic Laboratory and Pathology Research Roundup: July 30 - Insights

This week’s Research Roundup highlights a randomized trial of spheroid reservoir bioartificial liver in Porcine model of post-hepatectomy liver failure.

Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 3 - Insights

This week’s Research Roundup highlights biphenotypic acute leukemia versus myeloid antigen-positive ALL: Clinical relevance of WHO criteria for mixed phenotype acute leukemia.

Mayo Clinic Laboratory and Pathology Research Roundup: Feb. 19 - Insights

This week’s Research Roundup highlights the genomic analysis using regularized regression in high-grade serous ovarian cancer.

Mayo Clinic Laboratory and Pathology Research Roundup: April 9 - Insights

This week’s Research Roundup highlights genetic evidence for early peritoneal spreading in pelvic high-grade serous cancer.

Mayo Clinic Laboratory and Pathology Research Roundup: April 16 - Insights

This week’s Research Roundup highlights the clinical and pathological phenotype of genetic causes of focal segmental glomerulosclerosis in adults.

Mayo Clinic Laboratory and Pathology Research Roundup: April 2 - Insights

This week’s Research Roundup highlights patterns of homozygosity in patients with uniparental disomy with detection rate and suggested reporting thresholds for SNP microarrays.

Mayo Clinic Laboratory and pathology research roundup: November 16 - Insights

This week’s research roundup features: Discovery of autoantibodies targeting nephrin in minimal change disease supports a novel autoimmune etiology.

Mayo Clinic Laboratory and Pathology Research Roundup: Feb. 12 - Insights

This week’s Research Roundup highlights the prediction of oncologic outcomes in Renal cell carcinoma after surgery.

Most Patients with Unknown Spinal Cord Disease Later Given Specific Diagnosis, Study Shows - Insights

A study by Mayo Clinic researchers found that most patients with suspected spinal cord inflammation of unknown cause have an alternative, specific diagnosis. The research is published in Neurology, the medical journal of the American...

Research Roundup Archives - Page 12 of 29 - Insights

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September 2023 - Laboratory Genetics & Genomics - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Laboratory Genetics and Genomics.

Mayo Clinic Laboratory and Pathology Research Roundup: Nov. 20 - Insights

This week’s Research Roundup highlights prehospital transfusion for gastrointestinal bleeding.

Mayo Clinic Laboratory and pathology research roundup: January 17 - Insights

This week's research roundup features: Exploring gene expression profiles in primary central nervous system vasculitis

Week in Review: April 22 - Insights

Today's highlights include: Study mines cancer genetics to help with targeted treatment, Mayo Clinic to launch staffing tool app to find 'right nurse for the right role', and new blood biomarker may lead to early diagnosis of frontotemporal...

Mayo Clinic Laboratory and Pathology Research Roundup: March 11 - Insights

This week’s Research Roundup highlights an assay to rapidly screen for immunoglobulin light chain glycosylation: a potential path to earlier AL diagnosis for a subset of patients and several other research articles by Mayo Clinic physicians...

Gynecological NGS panels offer cost-effective cancer testing: Sounak Gupta, M.B.B.S., Ph.D. - Insights

Sounak Gupta, M.B.B.S., Ph.D., explains how Mayo Clinic Laboratories' gynecological NGS panels provide focused assessments of gynecological cancers. The cost-effective tests fill the gap between single gene assays and large cancer panels,...

Sarcoma Targeted Gene Panel [Test in Focus] - Insights

Andre Oliveira, M.D., Ph.D., gives an overview of this testing available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing compares to previous testing approaches, and what clinical action...

High-Resolution Targeted Benzodiazepine Screen - Insights

In this “Hot Topic,” Paul Jannetto, Ph.D., highlights Mayo Clinic’s targeted benzodiazepine assay and discusses the advantages and limitations of various urine-screening assays as well as quantitative confirmatory testing to determine...

Industry Archives - Page 4 of 6 - Insights

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Research Roundup Archives - Page 3 of 29 - Insights

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Research Archives - Page 3 of 33 - Insights

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March 2023 - Cytopathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Cytopathology.

April 2022 - Breast Pathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Breast Pathology.

People Archives - Page 30 of 35 - Insights

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A Test in Focus Archives - Page 4 of 10 - Insights

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Pathways Case Studies: March 2021 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for March include the following sub-specialties: Pulmonary Pathology, Cardiovascular...

Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 24 - Insights

This week’s Research Roundup highlights the limitations of platform assays to measure serum 25OHD level impact on guidelines and practice decision-making.

August 2021 - Clinical Microbiology and Infectious Disease Pathology - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Microbiology.

Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 18 - Insights

This week’s Research Roundup highlights Mayo Clinic researchers who conducted a study to characterize the clinical, pathologic, and survival implications of non-V600 BRAF mutations in metastatic colorectal cancer.

Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 16 - Insights

This week’s Research Roundup highlights the role of deficient DNA mismatch repair status in patients with stage III colon cancer treated with FOLFOX adjuvant chemotherapy.

Ann Moyer, M.D., Ph.D., Makes a Case for Pharmacogenomics - Insights

Pharmacogenomic testing is still limited, despite ample research, the existence of guidelines, and the emerging evidence it can help patients. Ann Moyer, M.D., Ph.D., Co-Director of the Personalized Genomics Laboratory at Mayo Clinic in...

Mayo Clinic Discovers Gene Mutations Linked to Pancreatic Cancer, Calls for Expanded Testing - Insights

According to Mayo Clinic research published in JAMA, six genes contain mutations that may be passed down in families, substantially increasing a person’s risk for pancreatic cancer.

Mayo Clinic Laboratory and Pathology Research Roundup: June 25 - Insights

This week’s Research Roundup highlights the association between inherited germline mutations in cancer predisposition genes and risk of pancreatic cancer.

Mayo Clinic Laboratory and Pathology Research Roundup: Jan. 15 - Insights

This week’s Research Roundup highlights how the loss of FOXO1 cooperates with TMPRSS2-ERG overexpression to promote prostate tumorigenesis and cell invasion.

Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 4 - Insights

This week’s Research Roundup highlights individual patient-level meta-analysis of the performance of the Decipher genomic classifier in high-risk men after prostatectomy to predict development of metastatic disease.