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Gadolinium-based contrast agents (GBCAs) have revolutionized MRIs by increasing the clinical utility and detection sensitivity of these exams. GBCAs also contain gadolinium, a rare earth metal with unique chemical properties. This article...
MCL Microbiology Test Request MC0767
MCL Microbiology Test Request Complete print Reset Form Microbiology Test Request Client Information required Client Patient Information required Patient ID Medical Record
Calprotectin and Inflammatory Bowel Disease - Insights
The differential diagnosis for inflammatory bowel disease (IBD) includes irritable bowel syndrome (IBS). While the clinical presentation is similar, IBD is an inflammatory disease, while IBS is a noninflammatory disease. View this "Hot...
MSA Patient Holds Steady Following Small Group Study of Stem Cell Therapy - Insights
Steve Day experiences balance issues, sleeping problems, and irregular blood pressure stem from a rare, unusual neurodegenerative disease—multiple system atrophy. Read his story.
The Collective Wisdom of Biobanks - Insights
Since ancient times, physicians have analyzed patient specimens to diagnose illness. Now, our samples can do far more than diagnose. They can help researchers find treatments for the unmet needs of patients.
Our staff, our stories: Andrew "Roo" Yori - Insights
Andrew “Roo” Yori’s persistence and athletic gifts allowed him to achieve his dream of becoming an American Ninja Warrior in 2016.
Applying the Staffing-to-Workload Methodology: Basic Staffing Model - Insights
Mike Baisch, Systems Engineer at Mayo Clinic, discusses how to apply the staffing-to-workload methodology to a series of case studies. This post highlights a “basic” staffing model.
The Metabolic Autopsy: Postmortem Screening in Cases of Sudden, Unexpected Death - Insights
In cases of sudden or unexpected death, autopsy evaluation can include a biochemical analysis to identify deaths caused by fatty acid oxidation disorders.
MCL - Renal Diagnostics Test Request - MC0767-11
MCL - Renal Diagnostics Test Request
Multicenter Collaboration Defends against Vector-Borne Diseases - Insights
Teamwork is critical among staff from Mayo Clinic, the Centers for Disease Control and Prevention, Minnesota Department of Health, and the University of Wisconsin-Madison in order to keep tabs on tick trends and defend against vector-borne...
Diagnostic Testing Algorithms for Celiac Disease - Insights
In this month's "Hot Topic," Melissa Snyder, Ph.D., co-director of the antibody immunology laboratory at Mayo Clinic, discusses celiac disease and the role of diagnostic testing algorithms.
In the fall of 2017, Shayla Polanchek, a recent recipient of a heart transplant at Mayo Clinic in Rochester, Minnesota, returned to campus to review the specimen of her old heart, the one that had been removed from her chest. She had asked...
New tests launched in November - Insights
In November 2021, Mayo Clinic Laboratories announced thirty four new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Raising the Bar on Newborn Screening Test Performance - Insights
Newborn screening panels that test for a variety of conditions are available in every state; however, test performance and response rate by each state are very different. Mayo Clinic's Biochemical Genetics Laboratory created the...
MCL - Therapeutics Test Request Form - MC0767-19
MCL - Therapeutics Test Request Form
JoAnne Michael’s symptoms started with dizziness and forgetfulness before down spiraling into severe confusion, crying jags, and brain seizures. ER doctors at her local hospital initially thought she was on drugs. JoAnne, terrified,...
Autoimmune Encephalopathy Testing - Mayo Clinic Laboratories
Our phenotype specific testing for autoimmune encephalopathy contains only clinically relevant antibodies providing accurate answers for treatment guidance.
Neuroimmunology: Updates and antibody test utilization - Insights
In this month’s “Hot Topic,” Andrew McKeon, M.B., B.Ch., M.D., reviews the use of neurological phenotype-based evaluations, the move away from the paraneoplastic evaluation, and upcoming changes to test profiles.
High-resolution targeted stimulant and phencyclidine (PCP) screen - Insights
In this month’s “Hot Topic,” Paul Jannetto, Ph.D., discusses the high-resolution targeted stimulant and PCP screening test from Mayo Clinic Laboratories, which offers sensitivity and specificity for use in the monitoring and management of...
Autoimmune Encephalopathy Testing - Mayo Clinic Laboratories
Our phenotype specific testing for autoimmune encephalopathy contains only clinically relevant antibodies providing accurate answers for treatment guidance.
Behind the scenes in neural antibody testing - Insights
In this month’s “Hot Topic,” John Mills, Ph.D., explains the central role of tissue immunofluorescence in the identification of neural antibodies and discusses the benefits of an integrated laboratory approach to the development and...
QuantiFERON-TB Gold Plus - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D. will discuss a new interferon-gamma release assay that can assist in the detection of individuals that are infected with tuberculosis.
Antibody Prevalence in Epilepsy and Encephalopathy (APE2) Score - Insights
In this month’s “Hot Topic,” Divyanshu Dubey, M.B.B.S., discusses how patients with encephalopathy and/or epilepsy of unknown etiology may have an autoimmune or paraneoplastic cause.
Lyme Neuroborreliosis - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., will discuss diagnostic testing options for patients with suspected neuroinvasive Lyme disease or Lyme neuroborreliosis.
Diagnostic Testing Algorithms for Celiac Disease - Insights
In this month’s “Hot Topic,” Melissa Snyder, Ph.D., will review the diagnostic testing algorithms for celiac disease and highlight the advantages and limitations of certain tests, including serology and genetic assays.
MCL - Biochemical Genetics Test Request - MC0767-16A
MCL - Biochemical Genetics Test Request
Chromogenic Factor VIII and IX Assays: Impact on Diagnosis and Management of Hemophilia - Insights
In this month’s “Hot Topic,” Rajiv Pruthi, M.B.B.S., will discuss different types of hemophilia along with their pathologic basis. He will also cover various types of factor assays such as one stage and chromogenic factor assays for...
The diagnosis of Myeloproliferative Neoplasm (MPN) must include an integrated approach and combine the clinical findings with laboratory results. In our latest “Hot Topic,” Rong He, M.D., discusses the subclassification of MPNs and the use...
MCL Oncology Test Request Form T729 MC076703A
MCL Oncology Test Request Form T729 Complete print Reset Form Oncology Test Request Client Information required Client Patient Information required Patient ID Medical Record
MCL Urine PreservativesCollection and Transportation for 24Hour Urine Specimens MC123587
MCL Urine PreservativesCollection Transportation 24Hour Urine Specimens Urine Preservatives Collection Transportation 24 Hour Urine Specimens Department Laboratory Medicine Pathology Clinic
Applying the Staffing-to-Workload Methodology: Same-Day Testing Staffing Model - Insights
Mike Baisch, Principal Systems Engineer at Mayo Clinic, discusses how to apply the staffing-to-workload methodology to accommodate same-day testing requirements.
MCL - Neurology Specialty Testing Client Test Request - MC0767-02A
MCL - Neurology Specialty Testing Client Test Request
Learn more about matrix-assisted laser desorption/ionization-time of flight mass spectrometry and the identification of plasma cell disorders.
Learn more about matrix-assisted laser desorption/ionization-time of flight mass spectrometry and the identification of plasma cell disorders.
Selecting Pathology Specimens for Solid Tumors Next-Generation Sequencing - Insights
In this month’s “Hot Topic,” Sounak Gupta, M.B.B.S., Ph.D., discusses selecting tissues and other tissue considerations for molecular testing. He also reviews tissue metrics and requirements, which differ based on test platforms. It is...
Helicobacter pylori Infection: Serologic Testing Not Recommended [Communiqué] - Insights
Helicobacter pylori (H pylori) infection is among the most common bacterial infections worldwide with approximately one-half of the world’s population infected. Several invasive and noninvasive testing methods are available to detect H...
In this month’s “Hot Topic,” Paul Jannetto, Ph.D., discusses the use of qualitative urine screening assays and quantitative confirmatory testing to determine compliance in pain management patients.
Phlebotomy Top Gun: Order of Draw-Do We Still Care? - Insights
In this month’s “Hot Topic,” Brad Karon, M.D., Ph.D., will cover the need and evidence behind following the order of draw recommendations for routine blood collection. Specifically, does evidence demonstrate a need to collect serum tubes...
Pathways Case Studies: July 2020 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for July include the following sub-specialties: Bone and Soft Tissue & Pulmonary,...
Updated Test Promises Fewer False Positives in Newborn Screening for Krabbe Disease - Insights
Mayo Clinic’s Biochemical Genetics Laboratory has announced an updated second-tier test to detect Krabbe disease (KD) that uses psychosine (PSY) as a disease marker. The new test method has significantly higher sensitivity to detect this...
MCL - Hematopathology/Cytogenetics Test Request Form T726 - MC0767-05A
MCL - Hematopathology/Cytogenetics Test Request Form T726
ACHE 2017 Congress on Healthcare Leadership Live Blog - Insights
Andy Cousin, FACHE, Director of Product Management and Marketing for Mayo Medical Laboratories, is attending this year's ACHE Congress on Health Care Leadership conference in Chicago. He will be sharing his thoughts and photos from the...
Pediatric neuro-oncology informative cases - Insights
Neuro-oncology is a complex field undergoing rapid changes with the advancement and evolution of sophisticated genetic testing. Evidence continues to grow in support of broad molecular and cytogenetic analysis for patients with brain...
Pathways Case Studies: July 2022 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for July include the following sub-specialties: Gastroenterology Pathology,...
Pathways Case Studies: October 2022 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for October include the following sub-specialties: Cardiovascular Pathology,...
MCL Allergen Test Request - MC0767-08
MCL Allergen Test Request
Pathways Case Studies: March 2022 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for March include the following sub-specialties: Breast Pathology, Cardiovascular...
The Region 4 Stork (R4S) Collaborative Project - Insights
This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.
The Region 4 Stork (R4S) Collaborative Project - Insights
This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.
The Region 4 Stork (R4S) Collaborative Project - Insights
This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.