Mayo Clinic Laboratory and Pathology Research Roundup: April 2 - Insights
This week's research roundup feature: Follicular lymphoma (FL) is an indolent non-Hodgkin lymphoma of germinal center origin, which presents with significant biologic and clinical heterogeneity. Using RNA-seq on B cells sorted from 87 FL...
Mayo Clinic Laboratory and Pathology Research Roundup: March 19 - Insights
This week's research roundup feature: The revised 4th edition of the World Health Organization (WHO4R) classification lists myelodysplastic syndromes with ring sideroblasts (MDS-RS) as a separate entity with single lineage (MDS-RS-SLD) or...
Bobbi Pritt, M.D., Discusses Hookworms with The Washington Post - Insights
The Washington Post recently reported on hookworms burrowing into a teenager's skin during a trip to Florida. Bobbi Pritt, M.D., Director of the Clinical Parasitology Lab and Co-Director of Vector-Borne Diseases Lab Services at Mayo Clinic,...
Bobbi Pritt, M.D., on Asian Longhorned Tick in U.S - Insights
According to the Centers for Disease Control and Prevention (CDC), the Asian longhorned tick has spread across nine states since it first appeared in the U.S. Bobbi Pritt, M.D., Director of the Clinical Parasitology Laboratory and...
Mayo Clinic Laboratory and Pathology Research Roundup: May 21 - Insights
This week's research roundup feature: Monoclonal immunoglobulin (MIg) crystalline nephropathies are rare lesions resulting from precipitation of MIgs in the kidney as crystalline inclusions. They can be categorized into lesions with...
Innovative Alzheimer's disease diagnostic tool unveiled - Insights
Mayo Clinic Laboratories has marked a significant advancement in the fight against Alzheimer's disease with the introduction of an innovative diagnostic test. This noninvasive blood test accurately detects the p-Tau217 biomarker, indicative...
Mayo Clinic Laboratory and Pathology Research Roundup: January 30 - Insights
This week's research roundup feature: Incapacitated regulatory T cells (Tregs) contribute to immune-mediated diseases. Inflammatory Tregs are evident during human inflammatory bowel disease (IBD); however, mechanisms driving the development...
Mayo Clinic Laboratory and Pathology Research Roundup: January 23 - Insights
This week's research roundup feature: Measles virus (MV) vaccine strains have shown significant preclinical antitumor activity against glioblastoma (GBM), the most lethal glioma histology. In this first in human trial (NCT00390299), a...
Mayo Clinic Laboratory and Pathology Research Roundup: November 14 - Insights
This week's research roundup feature: Microaggressions between members of a team occur often in medicine, even despite good intentions. Such situations call for difficult conversations that restore inclusivity, diversity, and a healthy work...
Mayo Clinic Laboratory and Pathology Research Roundup: October 24 - Insights
This week's research roundup feature: Renal fibrosis is now recognized as a main determinant of renal pathology to include chronic kidney disease. Deposition of pathological matrix in the walls of glomerular capillaries, the interstitial...
Mayo Clinic Laboratory and Pathology Research Roundup: November 21 - Insights
This week's research roundup feature: Bicuspid aortic valve (BAV) is the most common congenital heart anomaly. Lifetime morbidity and whether long-term survival varies according to BAV patient-sub-groups are unknown. This study aimed to...
Mayo Clinic Laboratory and Pathology Research Roundup: November 7, 2023 - Insights
This week's research roundup feature: Cytomegalovirus (CMV) is a significant cause of morbidity and mortality among immunocompromised hosts, including transplant recipients. Antiviral prophylaxis or treatment is used to reduce the incidence...
Mayo Clinic Laboratory and pathology research roundup: May 30 - Insights
This week's research roundup feature: Clinical and molecular correlates of somatic and germline DDX41 variants in patients and families with myeloid neoplasms.
Nuclear Magnetic Resonance Lipoprotein Profile [Test in Focus] - Insights
Jeffrey (Jeff) Meeusen, Ph.D., gives an overview of the new nuclear magnetic resonance (NMR) lipoprotein profile available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing improves upon...
Never Let the Fear of Needles Keep You from Saving Lives - Insights
Benjamin Tetlie, a Financial Representative for Mayo Clinic Global Business Solutions, used to have a strong aversion to the idea of donating blood. However, when his coworkers organized a Blood Donor Unit Challenge, he wanted to...
Jeff Meeusen, Ph.D., Discusses New Blood Test on "Voice of America" - Insights
Jeff Meeusen, Ph.D., a clinical chemist and Co-Director of Cardiovascular Laboratory Medicine at Mayo Clinic, discussed Mayo Clinic's new blood test that helps combat the leading cause of death in the U.S. on Voice of America.
Linnea Baudhuin, Ph.D., Discusses the Real Cost of NGS - Insights
Linnea Baudhuin, Ph.D., Associate Professor of Laboratory Medicine and Pathology and Co-Director of the Personalized Genomics Laboratory, the Clinical Genomics Sequencing Laboratory, and the Cardiovascular Laboratory at Mayo Clinic in...
Sharon Zehe, J.D., Discusses the Risks of Open-Source Genetic Databases - Insights
Sharon Zehe, J.D., an attorney for the Department of Laboratory Medicine and Pathology at Mayo Clinic and a genetic privacy expert, discusses the risks utilizing open-source genetic databases.
Twin Cities Business Highlights Mayo Clinic Biobank Project - Insights
Mayo Clinic is one of more than 100 organizations across the U.S. that is funded by the National Institutes of Health to partner in the All of Us Research Program, which aims to enroll at least 1 million participants to better understand...
Mayo Clinic Laboratory and Pathology Research Roundup: Dec. 3 - Insights
This week’s Research Roundup highlights predicting renal function outcomes after partial and radical nephrectomy.
Mayo Clinic Laboratory and pathology research roundup: April 11 - Insights
This week's Research Roundup feature: A stress-induced cilium-to-PML-NB route drives senescence initiation.
Mayo Clinic Laboratory and pathology research roundup: August 30 - Insights
This week's research roundup features: Kidney biopsy chronicity grading in antineutrophil cytoplasmic antibody-associated vasculitis
Mayo Clinic Researchers Team Up with Johns Hopkins to Phase out Heart Attack Test - Insights
Researchers from Mayo Clinic and the Johns Hopkins University School of Medicine published an article in "JAMA Internal Medicine" outlining the elimination from clinical practice of a popular test for diagnosing heart attacks.
Mayo Clinic Laboratory and Pathology Research Roundup: June 26 - Insights
This week’s Research Roundup highlights expanded phenotypes and outcomes among 256 LGI1/CASPR2-IgG positive patients.
1964: Orange and Blue Calendar becomes Official #ThrowbackThursday - Insights
From surgical procedures to committee meetings, activities at Mayo Clinic are scheduled around “orange days” and “blue days.” How and why did those colors come to be?
Allan Jaffe, M.D., Discusses Effect of Highly Sensitive Cardiac Troponin in Healio - Insights
High-sensitivity cardiac troponin levels are strongly associated with the risk for incident heart failure. Allan Jaffe, M.D., Consultant and Chair of Mayo Clinic’s Division of Clinical Core Laboratory Services, with a joint appointment in...
Mayo Clinic Laboratory and Pathology Research Roundup: June 4 - Insights
This week’s Research Roundup highlights isolated hepatic non-obstructive sinusoidal dilatation, a 20-year single center experience.
Mayo Clinic Laboratory and Pathology Research Roundup: March 19 - Insights
This week’s Research Roundup highlights the analysis of cell-free DNA to assess risk of tumoremia following endoscopic ultrasound fine-needle aspiration of pancreatic adenocarcinomas.
One Donation—Lifetime of Change for Those in Need - Insights
Shelley Kleinwort, a Business Intelligence Manager for Mayo Medical Laboratories, has been donating blood for the last 25 years. Growing up in Byron, Minnesota, and being part of the Mayo Clinic community, she has always known the need for...
Allan Dietz, Ph.D., Director of the Human Cellular Therapy Laboratory (HCTL) at Mayo Clinic, was recently profiled in Mayo Clinic Magazine, highlighting his background and work in the HCTL.
Bobbi Pritt, M.D., Discusses Safe Tick Removal - Insights
Bobbi Pritt, M.D., Director of the Clinical Parasitology Laboratory in Mayo Clinic’s Department of Laboratory Medicine and Pathology, discussed how to safety remove ticks from skin with AccuWeather.com.
On the April 22 broadcast of Mayo Clinic Radio, co-hosts Tracy McCray and Tom Shives, M.D., spoke with Bobbi Pritt, M.D., Director of the Clinical Parasitology Laboratory, about an update on Lyme disease predictions for 2017.
William Morice, II, M.D., Ph.D., Discusses Leadership Challenges for Laboratory Medicine - Insights
William Morice, II, M.D., Ph.D., Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic in Rochester, and President of Mayo Medical Laboratories, recently presented "Leadership Challenges for Laboratory Medicine" at the...
Mayo Clinic Laboratory and pathology research roundup: December 20 - Insights
This week's research roundup features: Expanding the platelet inventory to mitigate the impact of severe shortages
Mayo Clinic Laboratory and pathology research roundup: April 18 - Insights
This week's Research Roundup feature: Renal involvement in systemic sclerosis.
Mayo Clinic Laboratory and pathology research roundup: April 25 - Insights
This week's Research Roundup feature: Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis.
Mayo Clinic Laboratory and pathology research roundup: May 23 - Insights
This week's research roundup feature: Relationship between BCL2 mutations and follicular lymphoma outcome in the chemoimmunotherapy era.
Week in Review: May 20 - Insights
Today's highlights include: US at risk of COVID-19 drug shortages this summer, Rochester startup Vyriad developing cancer-fighting viruses, and CDC expresses concern about possibility of undetected monkeypox spread in U.K.
Week in Review: May 13 - Insights
Today's highlights include: Pandemic gets tougher to track as COVID testing plunges, Rochester hospitals score top grades in safety, and Mayo Clinic breaks ground on $155M Minnesota hospital expansion.
New tests launched in September - Insights
In September 2022, Mayo Clinic Laboratories announced ten new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Chromium and Cobalt Testing [Test in Focus] - Insights
Chromium and cobalt blood tests are used to monitor exposure to these elements. Both of these elements are naturally occurring and widely distributed in the environment. Previously, serum samples were collected and used to monitor patients...
Alpha-gal testing [Test in Focus] - Insights
Joshua Bornhorst, Ph.D., associate director of Mayo Clinic's Clinical Immunoassay Lab, explains how humans can develop an allergy to the alpha-gal molecule, and he describes a new allergen antibody test that can be used to detect it. Dr....
MDM2 gene amplification [Test in Focus] - Insights
William Sukov, M.D., provides an overview of the MDM2 gene amplification assay — a test that looks for amplification of the MDM2 gene region on chromosome 12q. He reviews when this test should be ordered, how it compares to other test...
Plasma Cell Proliferative Disorder [Test in Focus] - Insights
Linda Baughn Ph.D. gives an overview of this new test available through Mayo Clinic Laboratories. She discusses when this testing should be ordered, how this testing improves upon other testing approaches, and what clinical action can be...
B-cell lymphoblastic leukemia monitoring for minimal residual disease [Test in Focus] - Insights
Min Shi, M.D., Ph.D., a hematologist and co-director of Mayo Clinic's Flow Cytometry Laboratory, explains recent updates to the B-cell lymphoblastic leukemia minimal residual disease flow cytometry assay. This test is used to identify...
Breakthrough Lab Tests for Detecting Alzheimer's Disease: Bill Morice, M.D., Ph.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the...
Mayo Clinic Laboratory and pathology research roundup: September 12 - Insights
This week's research roundup feature: Activated mast cells in periprosthetic joint infection-associated tissue.
Mayo Clinic Laboratory and pathology research roundup: September 5 - Insights
This week's research roundup feature: 16S rRNA gene PCR/Sequencing of heart valves for diagnosis of infective endocarditis in routine clinical practice.
Mayo Clinic Laboratory and pathology research roundup: June 6 - Insights
This week's research roundup feature: Utilizing mass spectrometry to detect and isotype monoclonal proteins in urine: Comparison to electrophoretic methods.
Mayo Clinic Laboratory and pathology research roundup: August 15 - Insights
This week's research roundup feature: Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis.