Transfusion Decisions - Insights
PACE / State of FLIn this month’s “Virtual Lecture” Justin Kreuter, M.D., discusses how coagulation works and how to make appropriate transfusion decisions.
Autoimmune Encephalitis Diagnosis and Misdiagnosis - Insights
PACEIn this month’s “Virtual Lecture” Eoin Flanagan, M.D., B.Ch., reviews how to diagnose autoimmune encephalitis, what to watch that may suggest a different diagnosis, discuss neural autoantibodies interpretation and putting test results...
PACE / State of FLThis month’s “Virtual Lecture” recognizes the importance of tracking tumor cell development and the heterogeneity in cancer cell growth dynamics at the clonal resolution and reveals features of tumor cell metastasis.
Applications of Molecular Pathology and the Diagnosis of Soft Tissue Neoplasms - Insights
PACE / State of FLIn this month’s “Virtual Lecture” Andrew Folpe, M.D., discusses applications of molecular pathology and the diagnosis of soft tissue neoplasms. This presentation is applicable for pathologists because so much of what is...
Advancing our Understanding of Immunoglobulins to Better Understand Disease - Insights
PACE / State of FLIn this month’s “Virtual Lecture,” David Murray, M.D., Ph.D., discusses how immunoglobin light chains are used to detect overexpressed immunoglobins which can be applied to distinguish patients with plasma cell disorders...
Mayo Clinic Laboratory and Pathology Research Roundup: November 14 - Insights
This week's research roundup feature: Microaggressions between members of a team occur often in medicine, even despite good intentions. Such situations call for difficult conversations that restore inclusivity, diversity, and a healthy work...
Mayo Clinic Laboratory and Pathology Research Roundup: October 24 - Insights
This week's research roundup feature: Renal fibrosis is now recognized as a main determinant of renal pathology to include chronic kidney disease. Deposition of pathological matrix in the walls of glomerular capillaries, the interstitial...
Mayo Clinic Laboratory and pathology research roundup: May 30 - Insights
This week's research roundup feature: Clinical and molecular correlates of somatic and germline DDX41 variants in patients and families with myeloid neoplasms.
CPT codes and LOINC update: December 2022 - Insights
This page includes updates posted to the site during the month of December.
Mayo Clinic Laboratory and pathology research roundup: April 11 - Insights
This week's Research Roundup feature: A stress-induced cilium-to-PML-NB route drives senescence initiation.
Mayo Clinic Laboratory and pathology research roundup: February 7 - Insights
This week's Research Roundup features: Maintenance of remission and risk of relapse in Myeloperoxidase-positive ANCA-associated Vasculitis with kidney involvement.
Mayo Clinic Laboratory and pathology research roundup: March 21 - Insights
This week's Research Roundup features: Performance comparisons of methylation and structural variants from low-input whole-genome methylation sequencing.
Mayo Clinic Laboratory and pathology research roundup: March 7 - Insights
This week's Research Roundup features: Membranous nephropathy in syphilis is associated with neuron-derived neurotrophic factor.
Mayo Clinic Laboratory and pathology research roundup: April 4 - Insights
This week's Research Roundup features: Fatal Human Rabies Infection with Suspected Host-mediated Failure of Post-Exposure Prophylaxis Following a Recognized Zoonotic Exposure-Minnesota, 2021.
Mayo Clinic Laboratory and pathology research roundup: April 18 - Insights
This week's Research Roundup feature: Renal involvement in systemic sclerosis.
Mayo Clinic Laboratory and pathology research roundup: April 25 - Insights
This week's Research Roundup feature: Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis.
Mayo Clinic Laboratory and pathology research roundup: May 23 - Insights
This week's research roundup feature: Relationship between BCL2 mutations and follicular lymphoma outcome in the chemoimmunotherapy era.
Mayo Clinic Laboratory and pathology research roundup: March 14 - Insights
This week's Research Roundup features: Novel through-the-scope suture closure of colonic Endoscopic Mucosal resection defects.
Mayo Clinic Laboratory and pathology research roundup: March 28 - Insights
This week's Research Roundup features: Elementary overview of heavy metals.
Mayo Clinic Laboratory and pathology research roundup: September 12 - Insights
This week's research roundup feature: Activated mast cells in periprosthetic joint infection-associated tissue.
Mayo Clinic Laboratory and pathology research roundup: September 5 - Insights
This week's research roundup feature: 16S rRNA gene PCR/Sequencing of heart valves for diagnosis of infective endocarditis in routine clinical practice.
Mayo Clinic Laboratory and pathology research roundup: August 15 - Insights
This week's research roundup feature: Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis.
Mayo Clinic Laboratory and pathology research roundup: August 22 - Insights
This week's research roundup feature: Association of plasma biomarkers of Alzheimer Disease with cognition and medical comorbidities in a biracial cohort.
Mayo Clinic Laboratory and pathology research roundup: July 4 - Insights
This week's research roundup feature: Emergence of inducible macrolide resistance in mycobacterium chelonae due to broad-host-range plasmid and chromosomal variants of the novel 23S rRNA methylase gene, erm(55).
Mayo Clinic Laboratory and pathology research roundup: July 25 - Insights
This week's research roundup feature: The clinical and molecular spectrum of ETV6 mutated myeloid neoplasms.
Mayo Clinic Laboratory and pathology research roundup: July 11 - Insights
This week's research roundup feature: Comparison of two assays to diagnose herpes simplex virus in patients with central nervous system infections.
Mayo Clinic Laboratory and pathology research roundup: June 13 - Insights
This week's research roundup feature: Plasma biomarkers for prediction of Alzheimer's disease neuropathologic change.
Mayo Clinic Laboratory and pathology research roundup: May 9 - Insights
This week's research roundup feature: Proprotein Convertase Subtilisin/Kexin Type 6 (PCSK6) is a likely antigenic target in membranous nephropathy and nonsteroidal anti-inflammatory drug use.
Mayo Clinic Laboratory and pathology research roundup: May 16 - Insights
This week's research roundup feature: Development and validation of an acute respiratory distress syndrome prediction model in Coronavirus Disease 2019: Updated lung injury prediction score.
Mayo Clinic Laboratory and pathology research roundup: June 6 - Insights
This week's research roundup feature: Utilizing mass spectrometry to detect and isotype monoclonal proteins in urine: Comparison to electrophoretic methods.
Week in Review: February 10 - Insights
Today's Highlights Include: USDA proposes new nutrition standards for school meals, virtual care system designed for COVID-19 grows into a multiuse digital health tool, and Mayo Clinic explores use of artificial intelligence. Is It Hype Or...
Phlebotomy Lab Operations - Insights
PACE / State of FL Phlebotomy and specimen collection services are on the forefront of patient diagnosis. However, more often than not, they are over shadowed by testing laboratories because they deliver the final test results. The focus of...
Early-Onset IBD: Genetic Testing and Clinical Applications - Insights
Identification of early-onset IBD patients may enable tailored treatment and surveillance plans. With over 50 genes implicated in early-onset IBD, genetic testing should be included in the workup of children under the age of six with IBD....
Testing Options for Patients with Chronic Diarrhea: A Focus on Bile Acid Malabsorption - Insights
A new serum test for bile acid malabsorption. Descriptions illustrate how the test can be used as a screening test and as a tool for therapeutic action.
Seeking, and finding, answers, comfort, and hope: Joe Mondloch - Insights
Joe Mondloch and his wife Sue have existed in a grey area of uncertainty due to the unpredictable autoimmune neurological illness Joe has lived with for the last seven years. Rare, incurable, and debilitating, the newly classified disorder...
MCL @Work: Sarah Mason - Insights
In her current role as senior manager for global logistics at Mayo Clinic Laboratories, Sarah Mason oversees the coordination of patient sample shipments by working with a network of stakeholders, couriers, carriers, and vendors. Sarah...
Generating awareness of the laboratory - Insights
Medical Laboratory Professionals Week, an annual celebration held in April, is a great time to raise awareness of the impact the laboratory has on patients and providers in the community. Lab Week is also an opportunity to spotlight the...
Anti-Platelet Factor 4 Antibody-Mediated Prothrombotic Syndromes - Insights
PACE / State of FLIn this month's "Virtual Lecture," Anand Padmanabhan provides a general overview and science in the field related to heparin-induced thrombocytopenia (HIT), vaccine-induced thrombotic thrombocytopenia (VITT), and...
Keys to Leading in Extraordinarily Difficult Times: Part 1 - Insights
PACE / State of FLIn this month’s “Virtual Lecture” Mark Hyde shares what he has learned during his 28 years of workplace consulting experience and counseling with thousands of employees concerning work topics such as stress, fatigue,...
Classification of Kidney Stone Composition Using an AI Model - Insights
PACE / State of FLThis month’s “Virtual Lecture,” discusses how artificial intelligence can be utilized to classify kidney stones while demonstrating improvement in quality and patient safety.
Complement Testing in the Diagnosis and Management of Thrombotic Microangiopathy - Insights
PACE / State of FLThis month’s “Virtual Lecture” discusses the clinical diagnosis and management, summarizes the testing modalities that guide diagnosis and management, and recognizes the utility of genetic testing as it relates to...
Mayo Clinic Laboratory and Pathology Research Roundup: November 28 - Insights
This week's research roundup feature: Microaggressions between members of a team occur often in medicine, even despite good intentions. Such situations call for difficult conversations that restore inclusivity, diversity, and a healthy work...
Mayo Clinic Laboratory and Pathology Research Roundup: December 5 - Insights
This week's research roundup feature: No human rabies post-exposure prophylaxis (PEP) failure has been documented in the United States using modern cell culture-based vaccines. In January 2021, an 84-year-old male died from rabies 6 months...
Mayo Clinic Laboratory and pathology research roundup: September 19 - Insights
This week's research roundup feature: There is a need to develop safe and effective pharmacologic options for the treatment of celiac disease (CeD); however, consensus on the appropriate design and configuration of randomized controlled...
Mayo Clinic Laboratory and Pathology Research Roundup: October 31 - Insights
This week's research roundup feature: It is widely held that heart failure (HF) does not cause exertional hypoxaemia, based upon studies in HF with reduced ejection fraction, but this may not apply to patients with HF and preserved ejection...
Mayo Clinic Laboratory and Pathology Research Roundup: October 17 - Insights
This week's research roundup feature: Given the prevalence of dementia and the development of pathology-specific disease modifying therapies, high-value biomarker strategies to inform medical decision making are critical. In-vivo tau...
Mayo Clinic Laboratory and Pathology Research Roundup: October 10 - Insights
This week's research roundup feature: Membranous nephropathy (MN) is a pattern of injury caused by autoantibodies binding to specific target antigens, with accumulation of immune complexes along the subepithelial region of glomerular...
Keys to Leading in Extraordinarily Difficult Times: Part 2 - Insights
PACE / State of FLIn this month’s “Virtual Lecture” Mark Hyde continues to share what he has learned during his 28 years of workplace consulting experience and counseling with thousands of employees concerning work topics such as stress,...
Mayo Clinic Laboratory and pathology research roundup: January 24 - Insights
This weeks research roundup features: Automated scoring of total inflammation in renal allograft biopsies
Mayo Clinic Laboratory and pathology research roundup: January 31 - Insights
This week's research roundup features: Emergence of restless legs syndrome during opioid discontinuation