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07/2023© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Abacavir Hypersensitivity Testing and Initial Patient Management Algorithm 1. Saag M, Balu R, Phillips E, et al. High sensitivity of human...
gastric_malt_posttherapy_follow-up_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 01/2022 B cells present but not diagnostic. Suspicious for lymphoma Few B cells present but not diagnostic. Favor reactive Diagnostic for MALT...
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 10/2019 Adulterant Survey Algorithm ■ ADULT / Adulterants Survey, Random, Urine ■ ADLTX / Adulterants Survey, Chain of Custody, Random, Urine Urine specimen...
vitamin_b12_deficiency_evaluation.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 03/2022 Vitamin B12 Deficiency Evaluation <150 ng/L>400 ng/L 150-400 ng/L ≤0.4 nmol/mL >0.4 nmol/mL INDETERMINATE ACASM / Pernicious Anemia Cascade,...
autoimmune-paraneoplastic-myelopathy-evaluation-algorithm-serum.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Myelopathy Evaluation Algorithm-Serum ■ TRIM46 antibody by CBA ■ TRIM46 antibody by IF titer assay ■ Amphiphysin...
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 04/2024 Assessment for Zika Virus Infection * For pregnant women who have a fetus with prenatal ultrasound findings consistent with congenital Zika virus...
full_gene_analysis_-_multi-gene_panels_versus_familial_targeted_testing.pdf
03/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Suspicion of a genetic condition The patient is the first family member to have genetic (DNA) testing for the suspected condition. Order full gene...
inflammatory-bowel-disease-diagnostic-testing-algorithm.pdf
YES <50 mcg/g <50 mcg/g Abnormal >50 mcg/g Normal ANCA present ASCA IgG and IgA absent ANCA absent ASCA IgG or IgA present ANCA absent ASCA IgG or IgA absent >120 mcg/g50-120 mcg/g NO Assessing a patient with diarrhea when differential...
galactosemia_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 07/2024 GALT <24.5 nmol/h/mg of hemoglobin GALT ≥24.5 nmol/h/mg of hemoglobin 2 variants identified 0–1 variants identified and discordant enzyme results 1...
autoimmune-paraneoplastic-movement-disorder-evaluation-algorithm-spinalfluid.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Movement Disorder Evaluation Algorithm-Spinal Fluid ■ Glutamic acid decarboxylase (GAD65) antibody assay ■ Antineuronal...
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 07/2021 Hepatitis E: Testing Algorithm for Diagnosis and Management Immunocompetent patients with abnormal liver enzyme levels and at risk for hepatitis E...
autoimmune-paraneoplastic-encephalopathy-evaluation-algorithm-spinal-fluid.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Encephalopathy Evaluation Algorithm-Spinal Fluid ■ Glutamic acid decarboxylase (GAD65) antibody assay ■ Antineuronal...
malignant_lymphoma__guideline_for_bone_marrow_staging_studies.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 09/2023 Bone Marrow Staging for Known or Suspected Malignant Lymphoma Algorithm Testing begins with: ■ PATHC / Pathology Consultation for lymph node...
hbv_infection-monitoring_before_and_after_liver_transplantation.pdf
HBV Infection–Monitoring Before and After Liver Transplantation 04/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. HBV DNA <104 IU/mL HBV DNA >104 IU/mL Anti-HBV drug treatment of choice ■ Initiate...
celiac-disease-comprehensive-cascade-test-algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2022 Celiac Disease Comprehensive Cascade Test Algorithm Selective IgA deficiency ■ Tissue transglutaminase antibody, IgG ■ Gliadin (deamidated)...
lysosomal_storage_disorders_diagnostic_algorithm_part_2.pdf
If deficient, MLD confirmed One of the following suspected: ■ Aspartylglucosaminuria ■ α-Mannosidosis ■ β-Mannosidosis ■ Pompe disease ■ Sandhoff disease ■ Schindler disease ■ Sialidosis ■ Galactosialidosis* ■ α-Fucosidosis* ■...
newborn_screen_follow-up_for_x-linked_adrenoleukodystrophy.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 03/2023 Newborn screen result: Elevated lysophosphatidylcholines C24:0, C26:0 Order POX / Fatty Acid Profile, Peroxisomal (C22-C26), Serum Elevated very...
hemophilia_carrier_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 07/2024 Hemophilia Carrier Testing Algorithm F8 gene variant previously identified in family? ■ If known variant is an Intron 1 Inversion variant, order...
hemophilia_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 07/2024 Hemophilia Testing Algorithm Is activity still decreased? Hemophilia A diagnosis If the activity assays are normal, consider an alternate bleeding...
autoimmune-paraneoplastic-axonal-neuropathy-evaluation-algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Axonal Neuropathy Evaluation Algorithm ■ AGNA immunoblot ■ AGNA IFA Titer ■ GFAP antibody CBA ■ GFAP antibody IFA...
newborn-screen-follow-up-elevated-c5-oh.pdf
05/2023© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Newborn Screen Follow-up for Elevated C5-OH Newborn screen result: Elevated 3-hydroxyisovaleryl- /2-methyl-3-hydroxybutyryl-carnitine...
helicobacter_pylori_diagnostic_algorithm.pdf
≥60 years old; OR Alarming signs and symptoms: ■ Family history of proximal gastrointestinal cancer ■ Previous malignancy of the esophagus or stomach ■ Unexplained iron-deficiency anemia ■ Palpable mass or lymphadenopathy ■ Melena ■...
cystic_fibrosis_molecular_diagnostic_testing_algorithm.pdf
03/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 2 mutations detected Cystic Fibrosis Molecular Diagnostic Testing Algorithm Suspicion of cystic fibrosis (CF) due to clinical history and/or sweat...
hiv_prenatal_testing_algorithm__including_follow-up_of_reactive_rapid_serologic_test_results.pdf
NEGATIVE Reactive results from: ■ Rapid HIV-1 antibody test (serum, plasma, or whole blood) ■ Rapid HIV-1/-2 antibody test (serum, plasma, or whole blood) ■ Rapid HIV-1 antigen/antibody test (whole blood) Reactive results from rapid HIV...
autoimmune-paraneoplastic-dysautonomia-evaluation-algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Autoimmune/Paraneoplastic Dysautonomia Evaluation Algorithm 05/2024 ■ AP3B2 antibody by CBA ■ AP3B2 antibody by IF titer assay ■ PCA-2 IFA titer■ ANNA-1...
cyp2d6_comprehensive_cascade_testing_algorithm.pdf
01/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. CYP2D6 Comprehensive Cascade Testing Algorithm* *Additional testing is performed to derive as accurate a phenotype as possible. AAlways...
neuromuscular_myopathy_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 12/2022 Neuromuscular Myopathy Testing Algorithm Inherited myopathy suspected Adult onset proximal myopathy phenotype Specific (other) phenotypes ■...
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MCL Infectious Specimen Shipping Guidelines MC1235168
MCL Infectious Specimen Shipping Guidelines Infectious Specimen Shipping Guidelines Shipper Responsibilities test send area considered shipper send specimens
The Past, Present, and Future of Laboratory Automation - Insights
PACE / State of FL - This “Continual Improvement” webinar provides an overview of automating laboratory workflows and its impact on the overall efficiency of testing by speeding up tasks, minimizing waste, reducing reagent usage, and...
Microsoft Word - mayo CLINIC MAIN CAMPUS of state testing approval license updated.docx
Out of State Laboratory Testing Date: September 6, 2024 RE: Out of State Testing Approval HFD-OS/HFDC-D431 MAYO CLINIC LABORATORIES-ROCHESTER MAIN CAMPUS is approved to perform Out of State Testing, located at 200 FIRST STREET...
Microsoft Word - mayo 2 out of state testing approval license updated.docx
Out of State Laboratory Testing Date: September 6, 2024 RE: Out of State Testing Approval HFD-OS41 MAYO CLINIC LABS-ROCHESTER SUPERIOR DRIVE is approved to perform Out of State Testing, located at 3050 SUPERIOR DRIVE NW,...
newborn_screen_follow-up_for_pompe_disease.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 09/2024 Newborn Screen Follow-up for Pompe Disease Newborn screen result: decreased acid alpha-glucosidase (GAA) Assess clinically (including...
newborn_screen_follow-up_for_krabbe_disease_galactocerebrosidase_and_psychosine.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 10/2024 Newborn Screen Follow-up for Krabbe Disease: Galactocerebrosidase and Psychosine Newborn screening for infantile/late infantile Krabbe disease ■...
PathWays Case Studies: Nov. 2018 - Insights
Mayo Clinic laboratory experts share three case studies in this month’s “PathWays” post and are challenging you to test your Clinical Pathology, Molecular Diagnostic, Hematopathology, and Dermatology pathology knowledge. Review the cases,...
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Operational updates - Insights
The latest operational updates from Mayo Clinic Laboratories, including holiday shipping schedules, information technology changes, and more.
Autoimmune Encephalopathy Testing - Mayo Clinic Laboratories
Our phenotype specific testing for autoimmune encephalopathy contains only clinically relevant antibodies providing accurate answers for treatment guidance.
Week in Review: April 21 - Insights
Top highlights include: Millions expected to lose dental care coverage, overdose deaths of elderly on the rise, and Minnesota Health Department urges caution for well owners as flood waters rise.
January 2023 - Biochemical Genetics - Insights
This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Biochemical Genetics.
MCL Metabolic Hematology Patient Information MC1235251
MCL Metabolic Hematology Patient Information Complete print Reset Form Metabolic Hematology Patient Information Instructions information requested important interpretation test
Precision medicine for obesity program - Insights
PACE/State of CA/State of FL - In this month’s “Virtual Lecture,” Andres Acosta, M.D., Ph.D., discusses how individualized medicine can play a role in obesity.
Final Rule on LDTs May Be Coming Soon: Bill Morice, M.D., Ph.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the...
pediatric-autoimmune-cns-demyelinating-disease-diagnostic-algorithm.pdf
10/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Pediatric Autoimmune Central Nervous System Demyelinating Disease Diagnostic Algorithm NEGATIVE PRESENT PRESENT ABSENT ABSENT Diagnosis:...
Black History Month: Bill Morice, M.D., Ph.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to honor Black...
Outreach Financial Management: The Basics and More - Insights
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congenital-disorders-of-glycosylation-algorithm.pdf
Unexplained developmental delay, multisystemic disease with or without a neurologic component, multiple unexplained abnormalities of basic laboratory resultsa ■ CDGN - consistent with type I CDG (congenital disorder of glycosylation)...
ISO15189 Accredited Certificate NEW 2024 PDF Ver.psmd
The organization named above is granted this accreditation in accordance with the recognized International Standard ISO 15189:2012, Medical Laboratories – Requirements for quality and competence. This accreditation demonstrates competence...
Allan Jaffe, M.D., Consultant and Chair of Mayo Clinic’s Division of Clinical Core Laboratory Services, with a joint appointment in the Division of Cardiovascular Diseases, participated in a U.S. Food and Drug Administration meeting about...
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