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newborn-screen-elevated-c16-c18-acylcarnitine.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 08/2023 Newborn screen result: ■ Elevated C16 acylcarnitine ■ Possible elevated 18:1 acylcarnitine Perform: Plasma ammonia, blood gas, glucose, electrolytes,...
autoimmune-paraneoplastic-epilepsy-evaluation-algorithm-serum.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Epilepsy Evaluation Algorithm-Serum ■ ANNA-1 antibody by immunoblot ■ ANNA-2 antibody by immunoblot ■ ANNA-2...
newborn_screen_follow-up_for_krabbe_disease_galactocerebrosidase.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 08/2024 Newborn Screen Follow-up for Krabbe Disease: Galactocerebrosidase Newborn screening result: decreased galactocerebrosidase (GALC) ■ GALC...
lysosomal_storage_disorders_screen_interpretive_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 04/2022 Lysosomal Storage Disorders Screen Interpretive Algorithm One of the following: ■ α-Mannosidosis ■ Aspartyglucosaminuria ■ β-Mannosidosis ■ Gaucher...
firstline-screening-autoimmune-liver-disease-algorithm.pdf
05/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. First-Line Screening for Autoimmune Liver Disease Algorithm Consider: ■ PBC2 / SP100 and GP210 Antibodies, IgG, Serum ■ LKM / Liver/Kidney...
Malaria Laboratory Testing.indd
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 04/2021 Malaria Laboratory Testing Algorithm 1 Malaria can be a rapidly fatal disease, particularly when due to Plasmodium falciparum, and less commonly...
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. AATHR / Thrombophilia Profile, Plasma and Whole Blood Testing begins with: ■ Prothrombin Time (PT), Plasma ■ Activated Partial Thromboplastin Time (APTT),...
autoimmune-paraneoplastic-movement-disorder-evaluation-algorithm-serum.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Movement Disorder Evaluation Algorithm – Serum ■ GFAP alpha subunit antibody by CBA ■ GFAP alpha subunit antibody by...
newborn-screen-elevated-c0-c16-c18.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 08/20/23 Newborn screen results: ■ Elevated or normal free carnitine (C0) ■ Elevated C0/C16+C18 ratio Perform: Plasma ammonia, blood gas, glucose,...
chimerism-recipient_germline_testing_algorithm.pdf
01/2022© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Chimerism–Recipient Germline Testing Algorithm Results are reported as “Performed”. Final report will be issued after testing for engraftment...
T800 MC4091-67CH MC4091-67CH.indd 1-2 11/14/2017 9:23:30 AM MC4091-67CH.indd 3-4 11/14/2017 9:23:30 AM
MCL Blood Spot Collections Instructions Flyer MC4091135
MCL Blood Spot Collections Instructions Flyer Blood Spot Collection Instructions Instructions Blood Collection Heelstick Fingerstick minutes place warmer
MCL - Blood Spot Collection Instructions (Spanish) - Brochure - MC4091-67SP
MCL - Blood Spot Collection Instructions (Spanish) - Brochure
testing_algorithm_for_the_screening_and_diagnosis_of_hepatitis_c.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 02/2022 Hepatitis C: Testing Algorithm for Screening and Diagnosis HCVQN / Hepatitis C Virus (HCV) RNA Detection and Quantification by Real-Time Reverse...
bile_acid-associated_tests_ordering_guide.pdf
Bile Acid-Associated Tests Ordering Guide Evaluation of Bowel Dysfunction Use to identify individuals with bile acid diarrhea (1) For screening order 7AC4 / 7AC4, Bile Acid Synthesis, Serum (2) For diagnosis order BAMRP / Bile...
assessment-dengue-virus-infection.pdf
08/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Assessment for Dengue Virus Infection Testing for dengue virus infection should be considered in individuals who meet both of the following...
pediatric-autoimmune-encephalopathy-cns-disorders-evaluation-algorithm-spinal-fluid.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Pediatric Autoimmune Encephalopathy/Central Nervous System Disorders Evaluation Algorithm-Spinal Fluid PCDEC / Pediatric Autoimmune...
celiac_disease_serology_cascade_test_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Interpretive report includes: ■ Serum IgA ■ Tissue transglutaminase antibody, IgA ■ Endomysial antibody, IgA ■ Gliadin (deamidated) antibody, IgA ■...
demyelinating-neuropathy-evaluation-algorithm.pdf
08/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Demyelinating Neuropathy Evaluation Algorithm Neurofascin-155 IgG4 IgG Monosialo GM1 titer is performed IgM Monosialo GM1 titer is performed IgG...
07/2023© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Abacavir Hypersensitivity Testing and Initial Patient Management Algorithm 1. Saag M, Balu R, Phillips E, et al. High sensitivity of human...
lupus_anticoagulant_profile_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2023 Lupus Anticoagulant Profile Testing Algorithm *Weak lupus anticoagulant may not inhibit DRVVT Mix ** Additional assays may be performed if...
gastric_malt_posttherapy_follow-up_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 01/2022 B cells present but not diagnostic. Suspicious for lymphoma Few B cells present but not diagnostic. Favor reactive Diagnostic for MALT...
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 10/2019 Adulterant Survey Algorithm ■ ADULT / Adulterants Survey, Random, Urine ■ ADLTX / Adulterants Survey, Chain of Custody, Random, Urine Urine specimen...
vitamin_b12_deficiency_evaluation.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 03/2022 Vitamin B12 Deficiency Evaluation <150 ng/L>400 ng/L 150-400 ng/L ≤0.4 nmol/mL >0.4 nmol/mL INDETERMINATE ACASM / Pernicious Anemia Cascade,...
autoimmune-paraneoplastic-myelopathy-evaluation-algorithm-serum.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Myelopathy Evaluation Algorithm-Serum ■ TRIM46 antibody by CBA ■ TRIM46 antibody by IF titer assay ■ Amphiphysin...
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 04/2024 Assessment for Zika Virus Infection * For pregnant women who have a fetus with prenatal ultrasound findings consistent with congenital Zika virus...
breast-gynecological-and-prostate-cancer-testing-algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 08/2023 Breast, Gynecological and Prostate Cancer Testing Algorithm Test ID Test description FMTT Familial Variant Targeted Testing; Order for individuals...
full_gene_analysis_-_multi-gene_panels_versus_familial_targeted_testing.pdf
03/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Suspicion of a genetic condition The patient is the first family member to have genetic (DNA) testing for the suspected condition. Order full gene...
inflammatory-bowel-disease-diagnostic-testing-algorithm.pdf
YES <50 mcg/g <50 mcg/g Abnormal >50 mcg/g Normal ANCA present ASCA IgG and IgA absent ANCA absent ASCA IgG or IgA present ANCA absent ASCA IgG or IgA absent >120 mcg/g50-120 mcg/g NO Assessing a patient with diarrhea when differential...
galactosemia_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 07/2024 GALT <24.5 nmol/h/mg of hemoglobin GALT ≥24.5 nmol/h/mg of hemoglobin 2 variants identified 0–1 variants identified and discordant enzyme results 1...
autoimmune-paraneoplastic-movement-disorder-evaluation-algorithm-spinalfluid.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Movement Disorder Evaluation Algorithm-Spinal Fluid ■ Glutamic acid decarboxylase (GAD65) antibody assay ■ Antineuronal...
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 07/2021 Hepatitis E: Testing Algorithm for Diagnosis and Management Immunocompetent patients with abnormal liver enzyme levels and at risk for hepatitis E...
autoimmune-paraneoplastic-encephalopathy-evaluation-algorithm-spinal-fluid.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Encephalopathy Evaluation Algorithm-Spinal Fluid ■ Glutamic acid decarboxylase (GAD65) antibody assay ■ Antineuronal...
malignant_lymphoma__guideline_for_bone_marrow_staging_studies.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 09/2023 Bone Marrow Staging for Known or Suspected Malignant Lymphoma Algorithm Testing begins with: ■ PATHC / Pathology Consultation for lymph node...
hbv_infection-monitoring_before_and_after_liver_transplantation.pdf
HBV Infection–Monitoring Before and After Liver Transplantation 04/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. HBV DNA <104 IU/mL HBV DNA >104 IU/mL Anti-HBV drug treatment of choice ■ Initiate...
celiac-disease-comprehensive-cascade-test-algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2022 Celiac Disease Comprehensive Cascade Test Algorithm Selective IgA deficiency ■ Tissue transglutaminase antibody, IgG ■ Gliadin (deamidated)...
lysosomal_storage_disorders_diagnostic_algorithm_part_2.pdf
If deficient, MLD confirmed One of the following suspected: ■ Aspartylglucosaminuria ■ α-Mannosidosis ■ β-Mannosidosis ■ Pompe disease ■ Sandhoff disease ■ Schindler disease ■ Sialidosis ■ Galactosialidosis* ■ α-Fucosidosis* ■...
newborn_screen_follow-up_for_x-linked_adrenoleukodystrophy.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 03/2023 Newborn screen result: Elevated lysophosphatidylcholines C24:0, C26:0 Order POX / Fatty Acid Profile, Peroxisomal (C22-C26), Serum Elevated very...
hemophilia_carrier_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 07/2024 Hemophilia Carrier Testing Algorithm F8 gene variant previously identified in family? ■ If known variant is an Intron 1 Inversion variant, order...
hemophilia_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 07/2024 Hemophilia Testing Algorithm Is activity still decreased? Hemophilia A diagnosis If the activity assays are normal, consider an alternate bleeding...
autoimmune-paraneoplastic-axonal-neuropathy-evaluation-algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Axonal Neuropathy Evaluation Algorithm ■ AGNA immunoblot ■ AGNA IFA Titer ■ GFAP antibody CBA ■ GFAP antibody IFA...
newborn-screen-follow-up-elevated-c5-oh.pdf
05/2023© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Newborn Screen Follow-up for Elevated C5-OH Newborn screen result: Elevated 3-hydroxyisovaleryl- /2-methyl-3-hydroxybutyryl-carnitine...
helicobacter_pylori_diagnostic_algorithm.pdf
≥60 years old; OR Alarming signs and symptoms: ■ Family history of proximal gastrointestinal cancer ■ Previous malignancy of the esophagus or stomach ■ Unexplained iron-deficiency anemia ■ Palpable mass or lymphadenopathy ■ Melena ■...
cystic_fibrosis_molecular_diagnostic_testing_algorithm.pdf
03/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 2 mutations detected Cystic Fibrosis Molecular Diagnostic Testing Algorithm Suspicion of cystic fibrosis (CF) due to clinical history and/or sweat...
hiv_prenatal_testing_algorithm__including_follow-up_of_reactive_rapid_serologic_test_results.pdf
NEGATIVE Reactive results from: ■ Rapid HIV-1 antibody test (serum, plasma, or whole blood) ■ Rapid HIV-1/-2 antibody test (serum, plasma, or whole blood) ■ Rapid HIV-1 antigen/antibody test (whole blood) Reactive results from rapid HIV...
autoimmune-paraneoplastic-dysautonomia-evaluation-algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Autoimmune/Paraneoplastic Dysautonomia Evaluation Algorithm 05/2024 ■ AP3B2 antibody by CBA ■ AP3B2 antibody by IF titer assay ■ PCA-2 IFA titer■ ANNA-1...
cyp2d6_comprehensive_cascade_testing_algorithm.pdf
01/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. CYP2D6 Comprehensive Cascade Testing Algorithm* *Additional testing is performed to derive as accurate a phenotype as possible. AAlways...
neuromuscular_myopathy_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 12/2022 Neuromuscular Myopathy Testing Algorithm Inherited myopathy suspected Adult onset proximal myopathy phenotype Specific (other) phenotypes ■...
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MCL Infectious Specimen Shipping Guidelines MC1235168
MCL Infectious Specimen Shipping Guidelines Infectious Specimen Shipping Guidelines Shipper Responsibilities test send area considered shipper send specimens