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Chromogenic Factor VIII and IX Assays: Impact on Diagnosis and Management of Hemophilia - Insights

In this month’s “Hot Topic,” Rajiv Pruthi, M.B.B.S., will discuss different types of hemophilia along with their pathologic basis. He will also cover various types of factor assays such as one stage and chromogenic factor assays for...

Oncology Testing - Mayo Clinic Laboratories

Our comprehensive test menu includes testing to aid in providing both diagnostic and prognostic information and aid in the treatment selection across the full spectrum of malignancies.

Neuro-oncology informative cases - Insights

Clinical studies at the Mayo Clinic have shown that this broad, but tumor-specific, genetic analysis has significant, and sometimes unexpected, clinical impact. The following case studies highlight the importance and clinical utility of...

Gadolinium Accumulation in Brain Tissue following Contrast-Enhanced MRI Has Not Been Shown to Have Harmful Side Effects - Insights

Gadolinium-based contrast agents (GBCAs) have revolutionized MRIs by increasing the clinical utility and detection sensitivity of these exams. GBCAs also contain gadolinium, a rare earth metal with unique chemical properties. This article...

Osmotic fragility testing - Insights

In this month’s “Hot Topic,” James Hoyer, M.D., discusses the importance of using a control tube during osmotic fragility testing.

Diagnostic Testing Algorithms for Celiac Disease - Insights

In this month's "Hot Topic," Melissa Snyder, Ph.D., co-director of the antibody immunology laboratory at Mayo Clinic, discusses celiac disease and the role of diagnostic testing algorithms.

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) - Insights

In this month's "Hot Topic," Eoin Flanagan, M.B., B.Ch., reviews the recent diagnostic criteria for Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD).

The Metabolic Autopsy: Postmortem Screening in Cases of Sudden, Unexpected Death - Insights

In cases of sudden or unexpected death, autopsy evaluation can include a biochemical analysis to identify deaths caused by fatty acid oxidation disorders.

New tests launched in November - Insights

In November 2021, Mayo Clinic Laboratories announced thirty four new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

Raising the Bar on Newborn Screening Test Performance - Insights

Newborn screening panels that test for a variety of conditions are available in every state; however, test performance and response rate by each state are very different. Mayo Clinic's Biochemical Genetics Laboratory created the...

Optic Neuritis in the Era of Biomarkers - Insights

Antibodies to aquaporin-4 and myelin oligodendrocyte glycoprotein (MOG) are recently described biomarkers seen in a subset of atypical optic neuritis which have revolutionized our understanding of the condition. In this “Hot Topic,” my...

Congenital disorders of glycosylation - Insights

In this month’s “Hot Topic,” Gessi Pino, a genetic counselor in the Biochemical Genetics Lab at Mayo Clinic, and Kimiyo Raymond, M.D., a clinical consultant in the laboratory and an expert in Congenital Disorders of Glycosylation (CDG),...

Alzheimer's Disease CSF Biomarkers - Insights

In this month's "Hot Topic," Alicia Algeciras, Ph.D., DABCC, and Joshua Bornhorst, Ph.D., DABCC, discuss Alzheimer's disease CSF biomarkers.

#ASH18 Live Blog - Insights

Our Mayo Clinic colleagues are in San Diego for the 60th American Society of Hematology Annual Meeting and Exhibition. Follow this blog for live updates from #ASH18 as we attend the conference, mingle with colleagues at booth #2927, and...

Diagnostic Testing Algorithms for Celiac Disease - Insights

In this month’s “Hot Topic,” Melissa Snyder, Ph.D., will review the diagnostic testing algorithms for celiac disease and highlight the advantages and limitations of certain tests, including serology and genetic assays.

Myeloproliferative Neoplasm: Morphology, Molecular Updates and Cost-Effective Test Utilization - Insights

The diagnosis of Myeloproliferative Neoplasm (MPN) must include an integrated approach and combine the clinical findings with laboratory results. In our latest “Hot Topic,” Rong He, M.D., discusses the subclassification of MPNs and the use...

New tests launched in December - Insights

In December 2022, Mayo Clinic Laboratories announced seventy-eight new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

Applying MASSFIX to Urine Samples - Insights

In this month's "Hot Topic," David Murray, M.D., Ph.D., reviews the role of urine testing for monoclonal gammopathies and discusses Mayo Clinic’s use of MASSFIX to replace traditional immunofixation testing.

Diagnostic Exploratory Testing - Insights

In this month's "Hot Topic," Nicole Boczek, Ph.D., assistant professor and laboratory director in the Department of Laboratory Medicine and Pathology, and Sarah Barnett, M.S., CGC, discuss diagnostic exploratory testing, explain why it’s...

Helicobacter pylori Infection: Serologic Testing Not Recommended [Communiqué] - Insights

Helicobacter pylori (H pylori) infection is among the most common bacterial infections worldwide with approximately one-half of the world’s population infected. Several invasive and noninvasive testing methods are available to detect H...

Lyme Disease Part 1: The Common Culprits Worldwide-Borrelia burgdorferi, Borrelia garinii, Borrelia afzelii - Insights

In this “Hot Topic,” Elitza Theel, Ph.D., discusses how common cases of presumed Lyme disease go unreported each year and discusses scenarios in which testing for Lyme disease is indicated and reviews both recommended and inappropriate...

Testing for Antibodies to SS-A/Ro in Autoimmune Diseases - Insights

In this month’s “Hot Topic,” Anne Tebo, Ph.D., discusses recent updates in the testing for anti-SS-A/Ro antibodies in systemic autoimmune rheumatic diseases.

quality-compliance.pdf

@2021 Mayo Foundation for Medical Education and Research Framework for Quality Updated: 12/13/2024 Mayo Clinic Laboratories measure quality not simply by accreditation and licensure, but also by how efficiently esoteric laboratory...

MayoACCESS - Mayo Clinic Laboratories

The MayoACCESS application is compatible with most Laboratory Information Systems (LIS) and networks and is well suited for multiple facility configurations (including subaccounts). Features of the MayoACCESS application...

Predictors to Direct Neural Antibody Testing in Autoimmune Encephalitis/Epilepsy - Insights

In this “Hot Topic,” Divyanshu Dubey, M.B.B.S., associate professor of laboratory medicine and pathology and neurology at Mayo Clinic, discusses various clinical and paraclinical features of autoimmune encephalitis, autoimmune seizures, and...

Pediatric neuro-oncology informative cases - Insights

Neuro-oncology is a complex field undergoing rapid changes with the advancement and evolution of sophisticated genetic testing. Evidence continues to grow in support of broad molecular and cytogenetic analysis for patients with brain...

The Region 4 Stork (R4S) Collaborative Project - Insights

This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.

The Region 4 Stork (R4S) Collaborative Project - Insights

This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.

The Region 4 Stork (R4S) Collaborative Project - Insights

This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.

The Region 4 Stork (R4S) Collaborative Project - Insights

This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.

The Region 4 Stork (R4S) Collaborative Project - Insights

This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.

The Region 4 Stork (R4S) Collaborative Project - Insights

This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.

The Region 4 Stork (R4S) Collaborative Project - Insights

This is a 6-part series describing the products and clinical tools of a laboratory quality improvement project called Region 4 Stork, or R4S.

Specific Drug Groups - Mayo Clinic Laboratories

Specific Drug Groups Use the following links to view information for specific drug categories: Alcohol Amphetamine-Type Stimulants...

Pathways Case Studies: August 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for August include the following sub-specialties: Bone and Soft Tissue Pathology,...

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