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IDH assay facilitates timelier leukemia treatment: Rong He, M.D. - Insights
In this test-specific episode of the "Answers From the Lab" podcast, Rong He, M.D., explains how Mayo Clinic Laboratories' IDHQ test improves upon next generation sequencing for assessing AML treatment options.
FDA-approved test expands options for Alzheimer's disease - Insights
Joshua Bornhorst, Ph.D., describes the new, FDA-approved Alzheimer's disease (AD) test and how it differs from Mayo Clinic Laboratories' existing AD evaluation. The laboratory will offer both tests, to ensure flexibility and options for...
Membranous nephropathy assay: PMND1 - Insights
John Lieske, M.D., describes Mayo Clinic Laboratories' new test for primary membranous nephropathy. PMND1 is a diagnostic cascade that provides a cost-effective approach to detecting antigens known to cause membranous nephropathy — a...
Assay finds genetic cause of low bile flow: Devin Oglesbee, Ph.D. - Insights
Devin Oglesbee, Ph.D., explains how Mayo Clinic Laboratories' cholestasis gene panel identifies mutations that cause low flow of bile from the liver. Test results help guide treatment decisions that can prevent liver damage.
Learn more about how direct ethanol biomarker testing at Mayo Clinic Laboratories provides heightened sensitivity and specificity to accurately assess alcohol use and alcohol use disorder.
December 2023 - Neuropathology - Insights
This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Neuropathology.
September 2023 - Cytopathology - Insights
This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Cytopathology.
In this month's "Hot Topic," Paul Jannetto, Ph.D., identifies how to determine new vs. residual use of marijuana in a patient, and teaches how to calculate the carboxy-tetrahydrocannabinol (carboxy-THC) to creatinine ratio along with a...
Infective Endocarditis - Insights
In this month’s “Hot Topic,” Robin Patel, M.D., will review the laboratory methods used to diagnose infectious endocarditis. Specifically, she’ll discuss the role of blood cultures, nucleic acid amplification tests, histopathology, and...
Pathways Case Studies: July 2020 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for July include the following sub-specialties: Bone and Soft Tissue & Pulmonary,...
Updated Test Promises Fewer False Positives in Newborn Screening for Krabbe Disease - Insights
Mayo Clinic’s Biochemical Genetics Laboratory has announced an updated second-tier test to detect Krabbe disease (KD) that uses psychosine (PSY) as a disease marker. The new test method has significantly higher sensitivity to detect this...
Aiming to advance understanding of hard-to-predict gastroenteropancreatic neuroendocrine tumors (GEP-NETs), Thermo Fisher Scientific joined forces with Mayo Clinic and BioPharma Diagnostics to validate and gain U.S. regulatory clearance of...
COVID-19: The pandemic that's forever changed laboratory testing - Insights
Since March 2020, the COVID-19 pandemic has had a lasting impact on the lives of millions of people around the world, including the many brave health care workers who risked their own health to provide lifesaving care to those infected by...
Browse our full menu of individual tests and panels that aid in the diagnosis of tick-borne diseases.
Join us at the American Academy of Neurology Annual Meeting to learn about the latest in autoimmune and genetic neurology testing.
Autoimmune Epilepsy Testing - Mayo Clinic Laboratories
Our phenotype specific testing for autoimmune epilepsy contains only clinically relevant antibodies providing accurate answers for treatment guidance.
Transforming clinical practice and changing outcomes for brain tumor patients - Insights
The genetic variability of glioma, and its more advanced relative glioblastoma, has made genetic testing to identify biomarkers associated with prognosis and treatment effectivity an integral component of care plan development. However, the...
Therapeutics events - Insights
TherapeuticS Creating the new standard of therapeutic management, together Mayo Clinic Laboratories’ evidence-based toxicology and pharmacogenomic testing
Improving diagnosis of rare congenital disorders - Insights
Experts at Mayo Clinic have developed a unique method of testing that combines new technology with novel bioinformatics to promptly detect a group of uncommon genetic conditions that are often difficult to identify.
Laboratory testing utilization: Coccidioides immitis/posadasii serologic testing - Insights
In this month's "Hot Topic," Elitza Theel, Ph.D., shares the recommended approach to serologic testing for assessment or infection with coccidioides.
Direct immunofluorescence for autoimmune bullous diseases - Insights
In this month’s “Hot Topic,” Julia Lehman, M.D., discusses a recent change to the direct immunofluorescence assay, specifically the addition of the IgG4 conjugate.
Mayo Clinic Team to Combat Arboviruses and Future Infectious Disease Threats in Belize - Insights
Mayo Clinic and the University of Notre Dame’s Eck Institute for Global Health have launched a four-tiered joint project to better characterize and further assist in the detection of vector-borne infectious diseases in Belize.
Discover cutting-edge movement disorder diagnostics at Mayo Clinic Laboratories, encompassing autoimmune and hereditary conditions.
Clinical excellence - Insights
Learn more about how Mayo Clinic Laboratories’ test offerings and services can help hospital laboratories enhance patient care and laboratory performance.
New AI-augmented test refines kidney stone analysis - Insights
Since March 2019, Paul Jannetto, Ph.D., director of the Metals Laboratory at Mayo Clinic, along with his colleagues across the enterprise and his laboratory staff, have developed, validated, and implemented an artificial intelligence...
Testing for a surprising antigen enables insight into a chronic kidney illness - Insights
Mayo Clinic renal pathologist Dr. Sanjeev Sethi identified NELL-1 as a biomarker for membranous nephropathy (MN) in 2019. Two years later, Dr. Sethi helped implement the first ever IHC test to detect NELL-1 antigen, which appears in about...
Learn how Mayo Clinic Laboratories and hospitals we work with around the world balance strong financial performance and world-class patient care.
Mayo Clinic Labs @Work: Ona Saras - Insights
As a clinical specialty representative, Ona Saras’ decade-long dedication to patient care and advocacy for cutting-edge testing at Mayo Clinic Laboratories has transformed lives across Northern California and Reno, Nevada. Through personal...
Part II of this series shows how a breakthrough discovery about how kidney stones form may open the way for new, unorthodox treatments. The discovery was made possible by joining University of Illinois’ geology and biology forces with Mayo...
Infectious Diseases - Insights
Learn how our clinical microbiology laboratory can aid in diagnosing pediatric illnesses caused by insects, fungal species, and parasites.
An emotional proposition for a pancreatic cancer survivor: Jim Smith - Insights
Since overcoming a life-threatening diagnosis five years ago, Jim Smith has embraced life. But each time he travels to Mayo Clinic for follow-up laboratory testing, a well of emotions rises up to remind him of life’s fragility. Thankfully,...
Connect with us at the American Academy of Neurology Annual Meeting to learn how our evaluations can inform your clinical practice.
Thankful for Tygh: The Derossett Family - Insights
A Mayo Clinic Laboratories newborn screening panel detects a rare disease and paves the way for life-sustaining treatment.
Shining light on one family's struggle: Barbara, Deborah, Pamela, and Rylie - Insights
Before testing at Mayo Clinic Laboratories, Barbara Domaille, Deborah Neville, Pamela Neville, and Rylie Ronnenberg thought there could be a genetic connection to the hip problems they shared. After the testing, they knew for sure.
New tests launched in August - Insights
In August 2022, Mayo Clinic Laboratories announced thirty-two new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Biopharma only testing - Insights
Find out how our suite of BioPharma Diagnostics-specific neurology testing can provide answers for your patients.
Our renal diagnostics are backed by a multidisciplinary approach and an award-winning team of Mayo Clinic nephrology experts, pathologists, and laboratory scientists who work at the intersection of research and patient care.
One of the biggest misunderstandings about genetic testing is a perception that once a variant is identified and analyzed thoroughly, using all the best tools available, it can be associated with a specific disease or condition. But many...
Our Staff, Our Stories: Darin Kittleson - Insights
From friendly neighbor, to a hero. Darin Kittleson was in the middle of his ordinary day snow plowing his driveway when he decided to plow his neighbor’s driveway, as well. That was when he heard the cry for help. Darin rushed inside as 911...
Monoclonal Gammopathy Informative Cases - Insights
Mayo Clinic Laboratories provides evaluation and consultation for the diagnosis and treatment of patients with hereditary and acquired hematologic disorders.
Integration, innovation, precision: Propelling leading-edge diagnostics - Insights
The third episode of “Life of a Specimen” video series discusses the integration that drives the development of innovative tests, including the movement disorders evaluation, at Mayo Clinic Laboratories.
Widening the net to capture elusive pathogens - Insights
Central nervous system infections, such as meningitis and encephalitis, can be devastating for affected patients. While specific treatments are available for some of these infections, it first requires identifying the precise cause of...
Yuma Regional Medical Center: Changing perceptions and powering growth - Insights
Looking to elevate laboratory operations, Yuma Regional’s hospital directors established a leadership model that pairs medical and administrative leaders, resulting in a changed perception of the laboratory’s ability to drive profitability...
Commercial laboratories - Insights
Mayo Clinic Laboratories is a one stop laboratory solution for commercial laboratories, offering the industry’s most comprehensive test menu, 24/7 customer service support and streamlined logistics to help clients meet their business goals.
Modified two-tiered testing for Lyme disease - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D., discusses the modified two-tiered testing algorithm for Lyme disease entirely based on enzyme immunoassays (EIA).
Whole exome sequencing for hereditary disorders - Insights
Cherisse Marcou, Ph.D., and Marissa Ellingson, M.S., CGC, discuss whole exome sequencing (WES) at Mayo Clinic Laboratories. The comprehensive evaluation uses next-generation sequencing to detect for single nucleotide variants, small...
Mayo Clinic Laboratories’ commitment to pediatric care is supported by over 150 years of experience informing diagnoses and treatment plans.
Developed through evidence-driven clinical innovation and designed to deliver clarity on drug and alcohol use, our testing delivers results that advance understanding and improve outcomes.
Lab discoveries fuel updates for autoimmune movement disorders test - Insights
Mayo Clinic Laboratories expanded movement disorders panel better identifies autoimmune conditions. Four recently identified biomarkers — septin-5, septin-7, neurochondrin, and adaptor protein-3B2 — have been added to the panel, and all...
Phage immunoprecipitation sequencing identifies previously unknown disease biomarkers - Insights
In Mayo Clinic’s Advanced Diagnostics Laboratory, there are dozens of projects underway at once to develop new technologies, discover novel findings, validate new tests, and support physicians in providing advanced patient care. For...