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Meet our experts - Insights

Connect with us at the 65th American Society of Hematology Annual Meeting and Exposition to learn how our evaluations can inform your clinical practice. Schedule a one-on-one session with our representatives.

Frequently asked questions - Insights

For patients at risk of plasma cell disorders, early identification is critical to ensure better outcomes. Mayo Clinic MASSFIX, our innovative approach uses matrix-assisted laser desorption/ionization time-of-flight mass spectrometry...

Frequently asked questions - Insights

For patients at risk of plasma cell disorders, early identification is critical to ensure better outcomes. Mayo Clinic MASSFIX, our innovative approach uses matrix-assisted laser desorption/ionization time-of-flight mass spectrometry...

Back from the brink: Sheila Lewis - Insights

Mayo Clinic Laboratories’ comprehensive approach to targeted antibody testing played a crucial and lifesaving role in moving Sheila Lewis to recovery from autoimmune encephalitis.

General screening - Insights

Check out Mayo Clinic Laboratories’ expert-developed screening and panel testing for lysosomal disorders (LDs).

Sphingolipidoses - Insights

Learn more about how Mayo Clinic Laboratories’ unique testing for sphingolipidoses, including Gaucher and Krabbe diseases, can confirm diagnosis and guide disease management.

Mayo Clinic Laboratory and pathology research roundup: April 11 - Insights

This week's Research Roundup feature: A stress-induced cilium-to-PML-NB route drives senescence initiation.

Enhanced technology safeguards patient specimens - Insights

Mayo Clinic's use of enhanced radio-frequency identification technology to track specimens from the clinical setting to the lab reduces the risk of errors and protects valuable — sometime irreplaceable — patient samples.

High-Sensitivity Troponin Assay Promises Novel Uses in Managing Patients with Chronic Heart Disease - Insights

After a long wait, the U.S. Food and Drug Administration has finally approved the Elecsys Troponin T Gen 5 STAT blood test. Recently, the Beckman hscTnI assay was also approved. These high-sensitivity troponin assays will benefit emergency...

A heart full of gratitude: Meckenzie Tinaglia - Insights

Two years ago, when 29-year-old Meckenzie Tinaglia experienced a series of seizure-like events shortly after a cardiac ablation procedure, she knew her heart was to blame. Her local providers, however, weren’t convinced. If not for Mayo...

Demyelinating neuropathies - Insights

Learn how our expert-backed testing can increase confidence when it comes to the identification of several demyelinating neuropathies.

Axonal autoimmune neuropathies - Insights

Find out about our panel-based approach to axonal autoimmune neuropathies, which we recommend because of the overlap in clinical symptoms.

Ganglioside-associated neuropathies - Insights

Learn how Mayo Clinic Laboratories’ ganglioside antibody evaluation can provide diagnostic clarity and a path forward for patients impacted by autoimmune peripheral neuropathy.

Autoimmune neurology evolution - Insights

Patients with autoimmune neurologic conditions deserve the best chance at an accurate diagnosis. These answers can make a real difference in a patient’s treatment and quality of life.

Immune-mediated necrotizing myopathy calculator - Insights

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Curtis Hanson, M.D., Discusses Prognostic Markers for Chronic Lymphocytic Leukemia - Insights

Curtis Hanson, M.D., discusses the importance of detecting immunoglobulin heavy-chain variable region gene (IGHV) when acquiring prognostic and potentially therapeutic information in chronic lymphocytic leukemia (CLL) patients in CAP TODAY.

Thrombotic microangiopathy (TMA) - Insights

View our comprehensive testing suite designed to confirm diagnosis and facilitate treatment of thrombotic microangiopathy.

Anticoagulant drug monitoring - Insights

Browse our growing menu of special coagulation drug assays designed for both routine monitoring and select clinical situations.

Preparation of Platelet-Poor Plasma for Special Coagulation Testing - Insights

In this months "Hot Topic," Christopher Desens, MLS(ASCP) discusses the preparation of platelet-poor plasma for coagulation testing.

Chromogenic Factor VIII and IX Assays: Impact on Diagnosis and Management of Hemophilia - Insights

In this month’s “Hot Topic,” Rajiv Pruthi, M.B.B.S., will discuss different types of hemophilia along with their pathologic basis. He will also cover various types of factor assays such as one stage and chromogenic factor assays for...

Use of Artificial Intelligence and Digital Slide Scanning for Detection of Intestinal Protozoa in Trichrome-Stained Stool Specimens - Insights

In this month's "Hot Topic," Bobbi Pritt, M.D., describes the challenges to traditional microscopy for the detection of protozoa in stool specimens, lists potential uses of artificial intelligence in parasite detection, and discusses...

Lyme Disease Part 1: The Common Culprits Worldwide-Borrelia burgdorferi, Borrelia garinii, Borrelia afzelii - Insights

In this “Hot Topic,” Elitza Theel, Ph.D., discusses how common cases of presumed Lyme disease go unreported each year and discusses scenarios in which testing for Lyme disease is indicated and reviews both recommended and inappropriate...

Mayo Clinic Laboratory and Pathology Research Roundup: April 16 - Insights

This week's research roundup feature: R0 resection and radiation therapy have been associated with improved overall survival (OS) in patients with thymic carcinoma (TC). Here, we analyzed which subgroups of patients derive the greatest...

Mayo Clinic Laboratory and Pathology Research Roundup: April 9 - Insights

This week's research roundup feature: Intrathecal delivery of autologous culture-expanded adipose tissue-derived mesenchymal stem cells (AD-MSC) could be utilized to treat traumatic spinal cord injury (SCI). This Phase I trial...

Mayo Clinic Laboratory and Pathology Research Roundup: April 30 - Insights

This week's research roundup feature: Patients with dementia with Lewy bodies (DLB) may have Alzheimers disease (AD) pathology that can be detected by plasma biomarkers. Our objective was to evaluate plasma biomarkers of AD and their...

Mayo Clinic Laboratory and Pathology Research Roundup: April 23 - Insights

This week's research roundup feature: Only 20 percent of renal and bladder cancer patients will show a significant response to immune checkpoint inhibitor (ICI) therapy, and no test currently available accurately predicts ICI response. We...

Laboratory testing utilization: Coccidioides immitis/posadasii serologic testing - Insights

In this month's "Hot Topic," Elitza Theel, Ph.D., shares the recommended approach to serologic testing for assessment or infection with coccidioides.

Avoid seller's remorse: Why owning your lab makes sense - Insights

For community health care providers, owning a laboratory has been likened to shoveling money down a giant drain. Cayuga Medical Center is challenging that narrative. Instead of selling, Cayuga is investing in its lab — which it considers a...

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Bobbi Pritt, M.D., Identifies Lyme Disease Signs and Symptoms - Insights

With tick season underway in parts of the United States, it's important to understand the signs and symptoms of Lyme disease to determine when to seek medical treatment. Bobbi Pritt, M.D., Director of the Clinical Parasitology Laboratory in...

Week in Review: March 3 - Insights

Today's Highlights Include: COVID-19 deaths remain low compared to previous winters, FDA authorizing first at-home combo flu/Covid test, and Rochester public schools evaluating mental health needs and services throughout the district.

Clean and dry kidney stones - Insights

To optimize laboratory evaluation of kidney stones, specimens must be both clean and dry. The sensitivity of the analytical method used to determine kidney stone composition requires samples be completely dry, since excess water in the...

Amyloidosis Testing - Mayo Clinic Laboratories

Mayo Clinic’s amyloid protein identification methodology is considered the gold standard because of the high sensitivity and accuracy with which it types amyloid proteins in paraffin-embedded specimens.

How an ex-NFL Linebacker Overcame His Greatest Opponent, Amyloidosis - Insights

Matt Millen, ex-pro NFL player, who played on four Super Bowl-winning teams underwent a nearly six-year medical journey in search for answers. Finally, he was diagnosed with amyloidosis using a new testing methodology at Mayo Clinic.

VEXAS syndrome - Insights

Find out more about UBA1Q, a quantitative droplet digital polymerase chain reaction (ddPCR) assay that targets seven possible mutations that can occur in the UBA1 gene and help identify VEXAS syndrome.

Myeloid Blast and Maturation Assessment by Flow Cytometry ("MDS Flow") - Insights

Flow cytometric immunophenotyping method can be useful in assessing myeloid dysmaturation. In this “Hot Topic,” Dragon Jevremovic, M.D., Ph.D., describes a new flow cytometric test to detect aberrant patterns of expression in the diagnosis...

Myeloproliferative neoplasms - Insights

Learn about our reflexive molecular testing protocols that are designed to guide proper utilization of myeloproliferative neoplasms.

Myeloproliferative Neoplasm: Morphology, Molecular Updates and Cost-Effective Test Utilization - Insights

The diagnosis of Myeloproliferative Neoplasm (MPN) must include an integrated approach and combine the clinical findings with laboratory results. In our latest “Hot Topic,” Rong He, M.D., discusses the subclassification of MPNs and the use...

Pathways Case Studies: October 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for October include the following sub-specialties Breast Pathology, Gynecological...

Alzheimer's Disease CSF Biomarkers - Insights

In this month's "Hot Topic," Alicia Algeciras, Ph.D., DABCC, and Joshua Bornhorst, Ph.D., DABCC, discuss Alzheimer's disease CSF biomarkers.

NeurologyLive highlights work of Neuroimmunology Laboratory - Insights

Staff within Mayo Clinic’s Neuroimmunology Laboratory perform a unique clinical autoimmune serology service to patients by bridging a leading, one-of-kind autoimmune neurology practice with cutting-edge research.

Lab Medicine Rounds Archives - Page 9 of 11 - Insights

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Lab Medicine Rounds Archives - Page 10 of 11 - Insights

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Lab Medicine Rounds Archives - Page 6 of 11 - Insights

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Lab Medicine Rounds Archives - Page 5 of 11 - Insights

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Lab Medicine Rounds Archives - Page 7 of 11 - Insights

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Detecting danger: Dan O'Bryan - Insights

Dan O’Bryan didn’t think his dizziness and lightheadedness were anything to worry about. Nearly 100 miles away, the team at Mayo Clinic that was remotely monitoring Dan’s heart could see the truth.

September 2023 - Cytopathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Cytopathology.

Lab Medicine Rounds Archives - Page 8 of 11 - Insights

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Minimal residual disease - Insights

Get full-spectrum minimal residual disease testing options, all from one laboratory, with experts to support testing decisions and results.