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Find out how our data-driven testing was developed by experts and uses innovative laboratory technology to monitor all stages of kidney disease.
Learn more about our comprehensive menu of COVID-19 molecular, serology, and related testing.
Diagnosis and inflammation monitoring - Insights
Patients with symptoms that arouse clinical suspicion of either inflammatory bowel disease (IBD) or irritable bowel syndrome (IBS) are both common and tough to differentiate.
Organic acid disorders - Insights
Check out how Mayo Clinic Laboratories testing for organic acid metabolism disorders can help provide early diagnosis that enable prompt intervention.
Thrombotic Microangiopathies (TMA) [Test in Focus] - Insights
Meera Sridharan, M.D., Ph.D., explains Mayo Clinic Labs’ testing approach for atypical hemolytic uremic syndrome (aHUS). The serological complement panel examines nine analytes to gain a thorough understanding of the complement cascade to...
Updates Streamline Autoimmune Neurology Testing: Anastasia Zekeridou, M.D., Ph.D. - Insights
Anastasia Zekeridou, M.D., Ph.D., explains how Mayo Clinic Laboratories' updated panels and methodology boost the accuracy and efficiency of testing for three autoimmune neurology biomarkers. Early diagnosis is key to managing debilitating...
Divyanshu Dubey, M.B.B.S., explains how Mayo Clinic Laboratories' unique PDE10A and TRIM46 tests facilitate the management of central nervous system disorders triggered by cancers. Early diagnosis and treatment are important for managing...
Patients with elevated LDL or "bad" cholesterol face even greater risk if their levels of small dense LDL cholesterol are also high. Vlad Vasile, M.D., Ph.D., and Leslie Donato, Ph.D., explain how Mayo Clinic Laboratories' sdLDL-c assay...
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CPT codes and LOINC update: March 2021 - Insights
The following list includes updates posted to mayocliniclabs.com during the month of March.
New tests launched in June - Insights
In June 2023, Mayo Clinic Laboratories announced 28 new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Testing Archives - Page 23 of 26 - Insights
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Learn more about how related prenatal testing at Mayo Clinic Laboratories can help determine the best course for managing a pregnancy.
New tests launched in October - Insights
In October 2020, Mayo Clinic Laboratories announced two new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
GFAP: Novel Test for a Newly Identified Meningoencephalomyelitis - Insights
Mayo Clinic Laboratories is the only laboratory in the world to offer testing for a novel form of autoimmune meningoencephalomyelitis. Known as autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy, the condition was identified...
Mayo Clinic Laboratory and Pathology Research Roundup: July 23 - Insights
This week’s Research Roundup highlights gastrointestinal and extra-intestinal manifestations of immunoglobulin G4-related disease.
Kelch-11 Autoantibody Test [Test in Focus] - Insights
Divyanshu (Div) Dubey, M.B.B.S., explains how Mayo Clinic Labs’ new Kelch-11 antibody test — the first in the world — can confirm diagnosis, guide treatment, and improve outcomes in patients affected by testicular cancer-associated...
Collagen VII Autoantibody-mediated Subepidermal Autoimmune Blistering Diseases - Insights
In this month’s “Hot Topic,” Julia Lehman, M.D., professor of dermatology and laboratory medicine and pathology, discusses a subepidermal disease mediated by collagen VII autoantibodies.
Autoimmune Epilepsy Testing - Mayo Clinic Laboratories
Our phenotype specific testing for autoimmune epilepsy contains only clinically relevant antibodies providing accurate answers for treatment guidance.
Mayo Clinic Laboratory and Pathology Research Roundup: December 26 - Insights
This week's research roundup feature: Histoplasma and Blastomyces antigen detection assays are commonly used diagnostic tools. However, a high level of cross-reactivity between these antigens prevents definitive pathogen identification by...
Updated assay guides diagnosis of autoimmune liver disease: Anne Tebo, Ph.D. - Insights
Anne Tebo, Ph.D., explains how Mayo Clinic Laboratories' updated ALDG2 assay helps with the evaluation of patients with suspected autoimmune liver disease. The panel also helps with the evaluation of liver disease of unknown etiology.
See how our unique panel includes testing for antibodies proven to be associated with paraneoplastic or cancer-associated retinopathy.
New tests launched in February - Insights
In February 2021, Mayo Clinic Laboratories announced three new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
New tests launched in August - Insights
In August 2021, Mayo Clinic Laboratories announced three new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
A Test in Focus Archives - Page 10 of 10 - Insights
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Pathways Case Studies: May 2020 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for May include the following sub-specialties: Bone and Soft Tissue & Infectious...
Learn more about how Mayo Clinic Laboratories’ genetic testing for pulmonary conditions can provide diagnostic confirmation for an array of inherited illnesses.
New tests launched in March - Insights
In March 2022, Mayo Clinic Laboratories announced eighteen new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
mast_cell_disorder_diagnostic_algorithm__bone_marrow.pdf
01/2025© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Mast Cell Disorder: Diagnostic Algorithm, Bone Marrow NORMAL ABNORMAL Mast cells observed Other hematologic cells observed Order initial testing: ■...
CPT codes and LOINC update: December 2024 - Insights
This will be the last CPT Codes and LOINC update. Read why.
Autoimmune Encephalopathy Testing - Mayo Clinic Laboratories
Our phenotype specific testing for autoimmune encephalopathy contains only clinically relevant antibodies providing accurate answers for treatment guidance.
Necrotizing Autoimmune Myopathy Testing - Mayo Clinic Laboratories
We offer advanced testing of the most pertinent antibodies associated with IMNM on a sensitive immunofluorescence-based assay providing fast results for patients.
New tests launched in September - Insights
In September 2022, Mayo Clinic Laboratories announced ten new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
New tests launched in November - Insights
Mayo Clinic Laboratories launched the following three tests in November.
Featured new tests in quarter two of 2025 - Insights
In the second quarter of 2025, Mayo Clinic Laboratories expanded its test catalog with several innovative new tests.
Mayo Clinic Laboratories releases new, first-to-U.S.-market pregnancy risk assessment - Insights
Mayo Clinic Laboratories now offers the first preeclampsia-specific test (Mayo ID: PERA) that can be used to stratify patients into low or high-risk categories, indicating whether a patient is at risk for developing preeclampsia with severe...
Hepatocellular Carcinoma Risk Panel with GALAD Score - Insights
In this “Hot Topic,” Joshua Bornhorst, Ph.D., assistant professor of laboratory medicine and pathology at Mayo Clinic, reviews biomarker component testing for hepatocellular carcinoma, explains the GALAD score, and explores GALAD score...
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. This case sub-specialty is Renal.
Learn more about Mayo Clinic Laboratories’ testing to identify and monitor nicotine use as part of a patient’s nicotine-use cessation treatment plan, before anesthesia/surgery, or as part of insurance policy assessments.
New tests launched in September - Insights
In September 2021, Mayo Clinic Laboratories announced seven new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Pathways Case Studies: March 2023 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for March include the following sub-specialties: Breast Pathology, Cytopathology,...
Prenatal - Mayo Clinic Laboratories
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There have been concerns in the U.S. recently about the possible harmful side effects from absorbing gadolinium-based contrast agents into the body during some MRI exams. To address some of the anxiety and concerns over this issue, Paul...
New Tests - Mayo Clinic Laboratories
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fabry_disease_newborn_screen-positive_follow-up.pdf
08/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Fabry Disease: Newborn Screen-Positive Follow-up False-positive newborn screen Disease-causing variant identified Newborn screen result: Decreased...
Nuclear Magnetic Resonance Lipoprotein Profile [Test in Focus] - Insights
Jeffrey (Jeff) Meeusen, Ph.D., gives an overview of the new nuclear magnetic resonance (NMR) lipoprotein profile available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing improves upon...
Autoimmune evolution - Insights
Mayo Clinic Laboratories is leading an evolution in autoimmune neurology diagnosis. To better reflect this testing evolution, and to reduce confusion and improve utilization for our clients, effective April 28, we are renaming our...
newborn-screen-follow-up-elevated-c3-dc-isolated.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Reviewed 05/2025 Newborn screen result: Isolated elevation of malonylcarnitine (C3-DC) Perform: Blood gas, glucose, electrolytes Order: ■ OAU / Organic...
Demyelinating neuropathies - Insights
Learn how our expert-backed testing can increase confidence when it comes to the identification of several demyelinating neuropathies.
Nonradioactive assay helps diagnose heparin reaction - Insights
Rajiv Pruthi, M.B.B.S., explains how Mayo Clinic Laboratories’ serotonin release assay achieves high sensitivity and specificity while avoiding the use of radioactive materials. Serotonin release testing is an important tool in the...