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Pathways Case Studies: December 2019 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for December include the following sub-specialties: Biochemical Genetics, Bone and...

Assay identifies biomarker of autoimmune encephalitis subtype: Andrew McKeon, M.B., B.Ch., M.D. - Insights

Antibody against the GABA-A receptor is a biomarker of autoimmune encephalopathy that occurs across the lifespan, and disproportionately affects children. In this test-specific episode of the "Answers From the Lab" podcast, Andrew McKeon,...

Pathways Case Studies: March 2021 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for March include the following sub-specialties: Pulmonary Pathology, Cardiovascular...

Pathways Case Studies: February 2021 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for February include the following sub-specialties: Neuropathology,...

April 2021 — Gastroenterology and Surgical Pathology Case 1 - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Gastroenterology Pathology and Surgical Pathology.

H. pylori - Insights

Helicobacter pylori, or H. pylori, is one of the world’s most common chronic bacterial infections. Estimated to impact 4.4 billion individuals globally, H. pylori affects 35% to 89% of children, depending the on the geographic region in...

Axonal autoimmune neuropathies - Insights

Find out about our panel-based approach to axonal autoimmune neuropathies, which we recommend because of the overlap in clinical symptoms.

Chromogenic Factor VIII and IX Assays: Impact on Diagnosis and Management of Hemophilia - Insights

In this month’s “Hot Topic,” Rajiv Pruthi, M.B.B.S., will discuss different types of hemophilia along with their pathologic basis. He will also cover various types of factor assays such as one stage and chromogenic factor assays for...

PD-L1 Testing by Immunohistochemistry - Insights

In this month's "Hot Topic," Anja Roden, M.D., discusses the role of PD-L1 interaction in the immune system, challenges of PD-L1 testing, and current PD-L1 companion testing in various tumor types.

New High-Resolution Targeted Opioid Screen: Superior Sensitivity and Specificity to Evaluate Adherence to Prescribed Opioid Therapy - Insights

In this month’s “Hot Topic,” Paul Jannetto, Ph.D., discusses the high-resolution targeted opioid screening test from Mayo Clinic Laboratories, which offers sensitivity and specificity for use in the monitoring and management of patients who...

December 2023 - Gynecological Pathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Gynecological Pathology.

Mayo Clinic Laboratory and Pathology Research Roundup: July 31 - Insights

This week’s Research Roundup highlights urinary extracellular vesicles of podocyte origin and renal injury in preeclampsia.

Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 2 - Insights

This week’s Research Roundup highlights immune-mediated autonomic neuropathies following allogeneic stem cell transplantation in acute myeloid leukemia.

Plummer Building Figures Commemorate a Contentious Election - and a Friendship Carved in Stone #ThrowbackThursday - Insights

When the iconic Plummer Building was constructed on Mayo Clinic's Rochester campus during the late 1920s, the building's designer and namesake, Henry S. Plummer, M.D., made sure it included a number of bas relief caricatures that would help...

Research Roundup Archives - Page 21 of 29 - Insights

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Mayo Clinic Laboratory and Pathology Research Roundup: July 16 - Insights

This week’s Research Roundup highlights how senolytics improve physical function and increase lifespan in old age.

Mayo Clinic Laboratory and Pathology Research Roundup: April 30 - Insights

This week’s Research Roundup highlights a model for predicting breast cancer risk in women with atypical hyperplasia.

Mayo Clinic Laboratory and Pathology Research Roundup: Dec. 18 - Insights

This week’s Research Roundup highlights different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis.

Updates Streamline Autoimmune Neurology Testing: Anastasia Zekeridou, M.D., Ph.D. - Insights

Anastasia Zekeridou, M.D., Ph.D., explains how Mayo Clinic Laboratories' updated panels and methodology boost the accuracy and efficiency of testing for three autoimmune neurology biomarkers. Early diagnosis is key to managing debilitating...

Mayo Clinic Develops First-in-U.S. Neurology Test to Distinguish Spectrum of Autoimmune Demyelinating Diseases from Multiple Sclerosis - Insights

Mayo Clinic has launched a first-in-the-U.S. clinical test that will help patients who recently have been diagnosed with an inflammatory demyelinating disease but may be unsure of the exact disorder.

January 2023 - Gastroenterology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Gastroenterology Pathology.

July 2022 - Laboratory Genetics and Genomics and Molecular Pathology - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialties are Laboratory Genetics and Genomics and Molecular Pathology.

Hereditary epilepsy - Insights

Find out how we perform in-depth mutation and copy number variant analysis to determine causes of epilepsy and identify potential treatment options.

Mayo Clinic-developed mass spectrometry assay improves detection of monoclonal proteins, advancing outcomes in hard-to-treat diseases - Insights

The assay is now recommended for diagnosing and monitoring patients with monoclonal protein disorders and exclusively available through Mayo Clinic Laboratories– Rochester.

Hepatocellular Carcinoma Risk Panel with GALAD Score - Insights

In this “Hot Topic,” Joshua Bornhorst, Ph.D., assistant professor of laboratory medicine and pathology at Mayo Clinic, reviews biomarker component testing for hepatocellular carcinoma, explains the GALAD score, and explores GALAD score...

Cytomegalovirus Antiviral Resistance Testing: A New Assay for Detection of Mutations Associated with Antiviral Resistance in CMV - Insights

Cytomegalovirus, or CMV, is a common cause of disease in the transplant population. In some patients who are diagnosed with CMV and are on antiviral treatment for infections, the virus may develop resistance to the drugs. This “Hot Topic”...

May 2023 - Renal Pathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Renal Pathology.

February 2023 - Hematopathology Case Two - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Hematopathology.

Metagenomics - Insights

Mayo Clinic Laboratories cerebrospinal fluid metagenomic testing uses shotgun metagenomic sequencing to interrogate all microbial DNA and RNA present in a sample and determine the presence of potential pathogens.

July 2023 - Molecular Pathology - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Molecular Pathology.

Thiopurines - Insights

For children who require thiopurine medications (such as azathioprine and 6-mercaptopurine) to treat inflammatory bowel disease (IBD), understanding how thiopurines are metabolized is vital to choosing the most effective treatment. Because...

Therapeutic drug monitoring - Insights

Learn more about Mayo Clinic Laboratories’ clinically driven approach to therapeutic drug monitoring.

Five Steps to Improve Transfusion Medicine - Insights

Blood transfusion is the most common procedure performed in hospitals in the U.S. Yet published evidence shows significant gaps in clinicians' knowledge of this critical aspect of patient care, including possible adverse reactions that can...

Phlebotomy Top Gun: Order of Draw-Do We Still Care? - Insights

In this month’s “Hot Topic,” Brad Karon, M.D., Ph.D., will cover the need and evidence behind following the order of draw recommendations for routine blood collection. Specifically, does evidence demonstrate a need to collect serum tubes...

testing_algorithm_for_the_screening_and_diagnosis_of_hepatitis_c.pdf

© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 02/2022 Hepatitis C: Testing Algorithm for Screening and Diagnosis HCVQN / Hepatitis C Virus (HCV) RNA Detection and Quantification by Real-Time Reverse...

Phlebotomy Top Gun: Drawing Blood from a Patient Receiving Intravenous Fluids - Insights

In this month’s “Hot Topic,” Brad Karon, M.D., Ph.D., presents a case-based scenario on drawing blood from a patient receiving intravenous fluids.

Mayo Clinic Laboratory and Pathology Research Roundup: March 20 - Insights

This week’s Research Roundup highlights how AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction.

People Archives - Page 31 of 35 - Insights

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Yuma Regional Medical Center: Strategic expansion to serve a growing community - Insights

Faced with a population increase and the need to expand both laboratory testing capacity and capabilities, Yuma Regional Medical Center leaned into its relationship with Mayo Clinic Laboratories to gain insights to strengthen community...

Cayuga Medical Center: Building a world-class lab that drives revenue - Insights

Cayuga Medical Center sought to challenge the narrative that a hospital’s lab is an expensive liability by positioning themselves as the laboratory of choice in their area.

Myasthenia Gravis [Test in Focus] - Insights

Christopher Klein, M.D., discusses Mayo Clinic’s updated myasthenia gravis and Lambert-Eaton syndrome testing approach. Automatic reflex to second-line testing saves time and increases sensitivity and specificity to confirm diagnosis in...

Mayo Clinic Labs @Work: Sherri Hawkins - Insights

With nearly 30 years at Mayo Clinic, Sherri Hawkins has served in a wide range of laboratory-related roles. Beginning as a laboratorian on the bench and now serving as Group Purchasing Organization (GPO) manager, Sherri has been able to...

Cutting-edge lab work cracks a medical mystery: Kenneth Hobby - Insights

Kenneth Hobby assumed his fever, fatigue, and aching pains in May 2018 were from another bout of malaria. He was on one of his frequent visits to Zambia in southern Africa, where the mosquito-borne parasite is common. But anti-malaria drugs...

MCL @Work: Joune Twist - Insights

Joune Twist has always embraced her natural interest for learning new information and improving processes. In 2019, her curiosity and previous work led her to join Mayo Clinic’s Neuroimmunology Lab. As a medical laboratory scientist, Joune...

Mayo Clinic Laboratories offers first test to detect recently discovered autoimmune disease associated with testicular cancer - Insights

Mayo Clinic Laboratories has launched a first-in-the-U.S. autoimmune test of the Kelchlike protein 11 antibody, or KLHL11, which is used to detect autoimmune disease associated with testicular cancer.

March 2021 — Cardiovascular Pathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Cardiovascular Pathology.

June 2023 - Liver Pathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Liver Pathology.

Nicotine - Insights

Learn more about Mayo Clinic Laboratories’ testing to identify and monitor nicotine use as part of a patient’s nicotine-use cessation treatment plan, before anesthesia/surgery, or as part of insurance policy assessments.

AHUSD - Overview: Atypical Hemolytic Uremic Syndrome Complement Panel, Serum and Plasma

Detecting deficiencies in the alternative pathway that can cause atypical-hemolytic uremic syndrome, dense deposit disease, and C3 glomerulonephritis A second-tier test that aids in the differential diagnosis of thrombotic...

Pathways Case Studies: August 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for August include the following sub-specialties: Bone and Soft Tissue Pathology,...