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Life of a Specimen - Insights

Take a deeper look at the care provided to laboratory testing specimens along their meticulous journey through Mayo Clinic Laboratories testing.

Mayo Clinic Laboratory and pathology research roundup: April 12 - Insights

This Feature Includes: Latent pulmonary vascular disease may alter the response to therapeutic atrial shunt device in heart failure.

Genetic liver disease - Insights

Identifying underlying genetic disorders plays an important role in the treatment and care of patients with liver disease. Appropriate use of screening tests in routine clinical practice can rule out possible causes of liver disease and...

October 2023 - Coagulation - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Coagulation.

Pathways Case Studies: October 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for October include the following sub-specialties Breast Pathology, Gynecological...

April 2023 - Ophthalmic Pathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Ophthalmic Pathology.

MCL @Work: Ben Levno - Insights

As a senior product manager for Mayo Clinic Laboratories, Ben Levno supports the neurology segment of specialty testing. While Mayo Clinic physicians have access to our world-renowned neurology testing to diagnose and care for patients,...

About Us - Insights

Mayo Clinic Laboratories isn’t just a reference lab. We’re also the diagnostic lab for a hospital, just like your lab. So we know the many benefits of keeping tests as close to patients as possible.

Every test tube connects to a patient: Quality control of specimens in the pre-analytic phase - Insights

Each day, some 40 to 45 thousand specimens are shipped to Mayo Clinic Laboratories in Rochester, Minnesota, from hospitals and other health care organizations around the world. And for every sample, there’s a patient to whom it belongs,...

Mayo Clinic Laboratories: Quality testing from start to finish - Insights

Guided by a patient-centric philosophy, Mayo Clinic Laboratories has a unique internal structure of quality specialists, coordinators, and engineers who constantly evaluate and improve laboratory operations. This structure supports a host...

Diagnostic ecosystem boosts access to timely Alzheimer's disease testing - Insights

Mayo Clinic Laboratories has developed a cutting-edge suite of Alzheimer's disease testing. The newest assays use blood samples, avoiding the need for lumbar punctures to obtain cerebrospinal fluid. The testing suite exemplifies Mayo Clinic...

Genetics - Mayo Clinic Laboratories

Our genetic testing was developed by experienced geneticists, genetic counselors, laboratory scientists, and bioinformaticians. We focus on providing easy to understand answers, interpreted by those same individuals who have an intimate...

A "sandbox" for innovation: The Advanced Diagnostics Laboratory - Insights

Mayo Clinic’s Advanced Diagnostics Laboratory (ADL) is a visionary space designed to foster innovation. The ADL has a direct impact on patient lives, bringing promising tests and services to patients at Mayo and around the world.

A comprehensive test menu explores genome for druggable targets to treat gastrointestinal cancers - Insights

Since 1992, cases of colorectal cancer have been on a slow decline, yet 52,550 people died from it in 2023. At Mayo Clinic, a cutting-edge menu of both germline (inherited genetic alterations) and somatic (tumors due to non-inherited...

October 2023 - Pulmonary Pathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Pulmonary Pathology.

It Remains Unknown: Link between Gadolinium Exposure via MRI Exams and Health Effects in Patients with Normal Renal Function - Insights

There have been concerns in the U.S. recently about the possible harmful side effects from absorbing gadolinium-based contrast agents into the body during some MRI exams. To address some of the anxiety and concerns over this issue, Paul...

Myasthenia Gravis [Test in Focus] - Insights

Christopher Klein, M.D., discusses Mayo Clinic’s updated myasthenia gravis and Lambert-Eaton syndrome testing approach. Automatic reflex to second-line testing saves time and increases sensitivity and specificity to confirm diagnosis in...

Antifungal Drug Susceptibility Testing of Yeast: A Primer for Beginners - Insights

In this month’s “Hot Topic,” Nancy Wengenack, Ph.D., discusses susceptibility testing of yeast for those who are considering performing it in their laboratory, perhaps for the first time, or for those who choose to send their yeast isolates...

Cytogenetic Testing for Pediatric Patients With Hematologic Malignancies - Insights

In this month's "Hot Topic," Patricia Greipp, D.O., discusses fluorescence in situ hybridization, or FISH testing, particularly related to pediatric patients with hematologic malignancies.

Alzheimer's Disease CSF Biomarkers - Insights

In this month's "Hot Topic," Alicia Algeciras, Ph.D., DABCC, and Joshua Bornhorst, Ph.D., DABCC, discuss Alzheimer's disease CSF biomarkers.

MML Prenatal Testing Brochure - MC2775-111

MML Prenatal Testing Brochure - PRENATAL TESTING COMPREHENSIVE SCREENING DIAGNOSTIC TESTING FETAL ABNORMALITIES WOMEN HEALTH CLINIC PRENATAL TESTING

Robin Patel, M.D., Elected to 2-Year Term on ASM Board of Directors - Insights

Robin Patel, M.D., Chair of the Division of Clinical Microbiology and a Consultant in the Clinical Microbiology and Infectious Diseases Laboratories at Mayo Clinic, has been elected to serve a two-year term on the American Society for...

Nonradioactive assay helps diagnose heparin reaction - Insights

Rajiv Pruthi, M.B.B.S., explains how Mayo Clinic Laboratories’ serotonin release assay achieves high sensitivity and specificity while avoiding the use of radioactive materials. Serotonin release testing is an important tool in the...

December 2022 - Renal - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Renal Pathology.

MayoComplete - Insights

Find out how our suite of MayoComplete next-generation sequencing panels puts patients on the right treatment path.

New Eligibility Guidelines for Blood Donors with Previous Cancer Diagnoses - Insights

To coincide with American Red Cross recommendations, the Mayo Clinic Blood Donor Program has redefined eligibility guidelines for donors who have had a history of previous cancer diagnoses.

August 2023 - Biochemical Genetics - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Biochemical Genetics.

Surprises in Coagulation Testing - Insights

In this “Hot Topic,” William Nichols, M.D., presents a case study that demonstrates how pre- and postanalytic variables of the patient and blood samples can have confounding effects on the laboratory evaluation of coagulation disorders.

What's New in Health Care Reform: Jan. 30 - Insights

Top highlights include: Alcohol overtakes Hepatitis C as the top reason for liver transplants, new research call vitamin D benefits into question, NIH funds first artificial pancreas study in the United States for pregnant women, cervical...

Compassionate, knowledgeable death care brings Mayo Clinic's mission full circle - Insights

The Office of Decedent Affairs plays a key role in Mayo Clinic’s mission as its staff guide families through the logistics and complexities of a loved one’s death with skill and empathy.

Pathways Case Studies: June 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for June include the following sub-specialties: Gastroenterology Pathology,...

Jerry Katzmann, Ph.D., Receives AACC Academy Award for Outstanding Contributions to Clinical Chemistry in a Selected Area of Research - Insights

Jerry Katzmann, Ph.D., an emeritus consultant in the Mayo Clinic Protein Immunology Laboratory, has received the AACC Academy Award for Outstanding Contributions to Clinical Chemistry in a Selected Area of Research.

Advanced Diagnostics Laboratory helps improve the way oncologists treat patients through development of the Mayo Complete Solid Tumor Panel - Insights

Founded in 2017, Mayo Clinic's Advanced Diagnostics Laboratory is a visionary space. In 2021, the lab developed the Mayo Complete Solid Tumor Panel, a clinically validated assay that analyzes 515 genes using next-generation sequencing. This...

Pathways Case Studies: December 2022 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for December include the following sub-specialties: Bone and Soft Tissue Pathology,...

February 2021 — Dermatopathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Dermatopathology.

April 2021 — Dermatopathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Dermatopathology.

Descendant of Mother Alfred Moes Visits Mayo Clinic #ThrowbackThursday - Insights

Last month, Mayo Clinic hosted a pair of distinguished visitors: Gerard and Margit Moes. The couple traveled from their home in Luxembourg to Rochester, Minnesota, to see and learn more about the place Gerard's ancestor, Mother Alfred Moes,...

December 2023 - Neuropathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Neuropathology.

New AI-augmented test refines kidney stone analysis - Insights

Since March 2019, Paul Jannetto, Ph.D., director of the Metals Laboratory at Mayo Clinic, along with his colleagues across the enterprise and his laboratory staff, have developed, validated, and implemented an artificial intelligence...

MSA Patient Holds Steady Following Small Group Study of Stem Cell Therapy - Insights

Steve Day experiences balance issues, sleeping problems, and irregular blood pressure stem from a rare, unusual neurodegenerative disease—multiple system atrophy. Read his story.

A web of care, close to home: Support on the cancer journey - Insights

Dr. Dollahite received world-class cancer treatment from a web of health care organizations, including Mayo Clinic in Rochester, Minnesota. Yet she never left New York; most of her treatment occurred in Ithaca. What made that possible was...

Multiplex PCR for Microbial Detection in Spinal Fluid (BIOFIRE FILMARRAY Meningitis/Encephalitis Panel) - Insights

In this month’s “Hot Topic,” Robin Patel, M.D., discusses the FilmArray meningitis/encephalitis (ME) panel, describing the panel, her experience with it, and an algorithm for its use.

Neuroimmunology: Updates and antibody test utilization - Insights

In this month’s “Hot Topic,” Andrew McKeon, M.B., B.Ch., M.D., reviews the use of neurological phenotype-based evaluations, the move away from the paraneoplastic evaluation, and upcoming changes to test profiles.

Raising the Bar on Newborn Screening Test Performance - Insights

Newborn screening panels that test for a variety of conditions are available in every state; however, test performance and response rate by each state are very different. Mayo Clinic's Biochemical Genetics Laboratory created the...

April 2023 - Gynecological Pathology - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Gynecological Pathology.

What's New in Health Care Reform Archives - Insights

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Staffing to Workload in Phlebotomy Areas: Indirect Effort - Insights

Mike Baisch, Principal Systems Engineer at Mayo Clinic, discusses staffing to workload in phlebotomy areas with a focus on indirect effort, which includes tasks performed that don’t involve the patient or a patient’s sample.

October 2022 - Cardiovascular - Insights

This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Cardiovascular Pathology.

Mayo Clinic Laboratory and pathology research roundup: December 27 - Insights

This week's research roundup features: Neuropathological findings in COVID-19: an autopsy cohort

Ceramide testing helps reduce risk of heart attack: Stephanie Blendermann - Insights

Her father was a heavy smoker who eventually needed bypass surgery for his clogged arteries, and three of her sisters died prematurely from heart attacks. So, as Stephanie Blendermann approached the age of 65, she had good reason to think...