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Testing Options for Patients with Chronic Diarrhea: A Focus on Bile Acid Malabsorption - Insights

A new serum test for bile acid malabsorption. Descriptions illustrate how the test can be used as a screening test and as a tool for therapeutic action.

Mayo Clinic Laboratory and pathology research roundup: July 25 - Insights

This week's research roundup feature: The clinical and molecular spectrum of ETV6 mutated myeloid neoplasms.

Mayo Clinic Laboratory and pathology research roundup: September 5 - Insights

This week's research roundup feature: 16S rRNA gene PCR/Sequencing of heart valves for diagnosis of infective endocarditis in routine clinical practice.

Mayo Clinic Laboratory and pathology research roundup: August 22 - Insights

This week's research roundup feature: Association of plasma biomarkers of Alzheimer Disease with cognition and medical comorbidities in a biracial cohort.

Mayo Clinic Laboratory and pathology research roundup: August 15 - Insights

This week's research roundup feature: Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis.

Mayo Clinic Laboratory and Pathology Research Roundup: October 24 - Insights

This week's research roundup feature: Renal fibrosis is now recognized as a main determinant of renal pathology to include chronic kidney disease. Deposition of pathological matrix in the walls of glomerular capillaries, the interstitial...

Autoimmune Encephalitis Diagnosis and Misdiagnosis - Insights

PACEIn this month’s “Virtual Lecture” Eoin Flanagan, M.D., B.Ch., reviews how to diagnose autoimmune encephalitis, what to watch that may suggest a different diagnosis, discuss neural autoantibodies interpretation and putting test results...

Mayo Clinic Laboratory and pathology research roundup: April 11 - Insights

This week's Research Roundup feature: A stress-induced cilium-to-PML-NB route drives senescence initiation.

Phlebotomy Lab Operations - Insights

PACE / State of FL Phlebotomy and specimen collection services are on the forefront of patient diagnosis. However, more often than not, they are over shadowed by testing laboratories because they deliver the final test results. The focus of...

An Artificial Intelligence-powered Approach Reveals Novel Features of Tumor Cell Metastasis - Insights

PACE / State of FLThis month’s “Virtual Lecture” recognizes the importance of tracking tumor cell development and the heterogeneity in cancer cell growth dynamics at the clonal resolution and reveals features of tumor cell metastasis.

Advancing our Understanding of Immunoglobulins to Better Understand Disease - Insights

PACE / State of FLIn this month’s “Virtual Lecture,” David Murray, M.D., Ph.D., discusses how immunoglobin light chains are used to detect overexpressed immunoglobins which can be applied to distinguish patients with plasma cell disorders...

Mayo Clinic Laboratory and pathology research roundup: July 4 - Insights

This week's research roundup feature: Emergence of inducible macrolide resistance in mycobacterium chelonae due to broad-host-range plasmid and chromosomal variants of the novel 23S rRNA methylase gene, erm(55).

Mayo Clinic Laboratory and pathology research roundup: September 12 - Insights

This week's research roundup feature: Activated mast cells in periprosthetic joint infection-associated tissue.

Mayo Clinic Laboratory and pathology research roundup: July 11 - Insights

This week's research roundup feature: Comparison of two assays to diagnose herpes simplex virus in patients with central nervous system infections.

Mayo Clinic Laboratory and Pathology Research Roundup: November 14 - Insights

This week's research roundup feature: Microaggressions between members of a team occur often in medicine, even despite good intentions. Such situations call for difficult conversations that restore inclusivity, diversity, and a healthy work...

Neuro-oncology: An integrated approach to interpreting genetic information from brain tumor samples - Insights

As part of Mayo Clinic’s Neuro-Oncology practice, the Division of Laboratory Genetics and Genomics tests about 50 brain tumors a week, and upwards of 1,500 brain tumors a year from all over the world.

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) - Insights

In this month's "Hot Topic," Eoin Flanagan, M.B., B.Ch., reviews the recent diagnostic criteria for Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD).

Top 5 reasons to attend this year's Leveraging the Laboratory Conference - Insights

This fall, healthcare professionals and laboratory outreach enthusiasts will travel to Chicago to attend Mayo Clinic's annual conference, "Leveraging the Laboratory." Outreach manager Jane Hermansen along with outreach solution strategists,...

Anti-Platelet Factor 4 Antibody-Mediated Prothrombotic Syndromes - Insights

PACE / State of FLIn this month's "Virtual Lecture," Anand Padmanabhan provides a general overview and science in the field related to heparin-induced thrombocytopenia (HIT), vaccine-induced thrombotic thrombocytopenia (VITT), and...

Complement Testing in the Diagnosis and Management of Thrombotic Microangiopathy - Insights

PACE / State of FLThis month’s “Virtual Lecture” discusses the clinical diagnosis and management, summarizes the testing modalities that guide diagnosis and management, and recognizes the utility of genetic testing as it relates to...

Mayo Clinic Laboratory and pathology research roundup: June 27 - Insights

This week's research roundup feature: SARS-CoV-2 spike codon mutations and risk of hospitalization after antispike monoclonal antibody therapy in solid organ transplant recipients.

Mayo Clinic Laboratory and pathology research roundup: July 18 - Insights

This week's research roundup feature: Natural history, predictors of development of extramedullary disease, and treatment outcomes for patients with extramedullary multiple myeloma.

Mayo Clinic Laboratory and pathology research roundup: August 1 - Insights

This week's research roundup feature: A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling.

Mayo Clinic Laboratory and pathology research roundup: September 19 - Insights

This week's research roundup feature: There is a need to develop safe and effective pharmacologic options for the treatment of celiac disease (CeD); however, consensus on the appropriate design and configuration of randomized controlled...

Mayo Clinic Laboratory and Pathology Research Roundup: October 17 - Insights

This week's research roundup feature: Given the prevalence of dementia and the development of pathology-specific disease modifying therapies, high-value biomarker strategies to inform medical decision making are critical. In-vivo tau...

Mayo Clinic Laboratory and Pathology Research Roundup: October 31 - Insights

This week's research roundup feature: It is widely held that heart failure (HF) does not cause exertional hypoxaemia, based upon studies in HF with reduced ejection fraction, but this may not apply to patients with HF and preserved ejection...

Mayo Clinic Laboratory and Pathology Research Roundup: December 5 - Insights

This week's research roundup feature: No human rabies post-exposure prophylaxis (PEP) failure has been documented in the United States using modern cell culture-based vaccines. In January 2021, an 84-year-old male died from rabies 6 months...

Mayo Clinic Laboratory and Pathology Research Roundup: November 28 - Insights

This week's research roundup feature: Microaggressions between members of a team occur often in medicine, even despite good intentions. Such situations call for difficult conversations that restore inclusivity, diversity, and a healthy work...

Mayo Clinic Laboratory and Pathology Research Roundup: October 10 - Insights

This week's research roundup feature: Membranous nephropathy (MN) is a pattern of injury caused by autoantibodies binding to specific target antigens, with accumulation of immune complexes along the subepithelial region of glomerular...

Keys to Leading in Extraordinarily Difficult Times: Part 2 - Insights

PACE / State of FLIn this month’s “Virtual Lecture” Mark Hyde continues to share what he has learned during his 28 years of workplace consulting experience and counseling with thousands of employees concerning work topics such as stress,...

Blood Cultures - Insights

PACE/State of FL - This "Phlebotomy Webinar" will review proper blood culture collection techniques and demonstrate how specimen quality can impact patient care.

Classification of Kidney Stone Composition Using an AI Model - Insights

PACE / State of FLThis month’s “Virtual Lecture,” discusses how artificial intelligence can be utilized to classify kidney stones while demonstrating improvement in quality and patient safety.

Mayo Clinic Laboratory and pathology research roundup: August 8 - Insights

This week's research roundup feature: Age-based versus young-adult thresholds for nephrosclerosis on kidney biopsy and prognostic implications for CKD.

Standard Operating Procedures (SOPs): The 5 W's and How - Insights

PACE/State of FL - The who, what, why, where, when and how of well written effective procedures that can: help to improve the quality of work within the organization, help reduce the number of errors and omissions, and help new people...

Hurricane Lee: Potential specimen delays - Insights

Hurricane Lee will be impacting the New England area and northeastern Canada this weekend. We are monitoring and tracking the situation with our logistics partners to minimize challenges. Your organization will be contacted directly by the...

Mayo Clinic Laboratory and pathology research roundup: October 3 - Insights

This week's research roundup feature: Gene fusions involving tumor protein p63 gene (TP63) occur in multiple T and B cell lymphomas and portend a dismal prognosis for patients. The function and mechanisms of TP63 fusions remain unclear, and...

Mayo Clinic Laboratory and pathology research roundup: September 26 - Insights

This week's research roundup feature: Semaglutide in HFpEF across obesity class and by body weight reduction.

Dr. Robin Patel shares periprosthetic joint infection findings in NEJM - Insights

The New England Journal of Medicine recently published new findings on periprosthetic joint infection by Dr. Robin Patel.

Testing for Antibodies to SS-A/Ro in Autoimmune Diseases - Insights

In this month’s “Hot Topic,” Anne Tebo, Ph.D., discusses recent updates in the testing for anti-SS-A/Ro antibodies in systemic autoimmune rheumatic diseases.

Staffing to Workload - Insights

PACE / State of FLThis Continual Improvement webinar will focus on a data driven and systematic approach to understand demand, identify idle time, and optimize work schedules. We will examine the different variations that exist when...

Mayo Clinic Laboratory and Pathology Research Roundup: December 26 - Insights

This week's research roundup feature: Histoplasma and Blastomyces antigen detection assays are commonly used diagnostic tools. However, a high level of cross-reactivity between these antigens prevents definitive pathogen identification by...

Mayo Clinic Laboratory and Pathology Research Roundup: December 12 - Insights

This week's research roundup feature: Most patients with solitary bone plasmacytomas (SBP) progress to multiple myeloma (MM) after definitive radiation therapy as their primary treatment. Whether the presence of high-risk (HR) cytogenetic...

Mayo Clinic Laboratories and Helix collaborate to provide comprehensive suite of laboratory services to biopharma customers - Insights

Mayo Clinic Laboratories, a leading reference laboratory, and Helix, the nation’s leading population genomics and viral surveillance company, today announced a new strategic collaboration that will provide life sciences customers access to...

Dr. Matt Binnicker sheds light on new Arcturus COVID-19 variant - Insights

Matthew Binnicker, Ph.D., director of Mayo Clinic’s Clinical Virology Laboratory, provides insight on the newest COVID-19 subvariant – XBB.1.16, also known as “Arcturus.”

How to grow your career in outreach management - Insights

On this episode of Mayo Clinic Laboratories “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, sits down with outreach solutions strategists Ellen Dijkman Dulkes and Brianne Newton to...

Why laboratory professionals should embrace the spotlight during Lab Week - Insights

On this episode of Mayo Clinic Laboratories’ “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager, returns with outreach solutions strategists Ellen Dijkman Dulkes and Brianne Newton to chat about National Medical...

KPIs: If you can't measure it, you can't manage it - Insights

In this episode of Mayo Clinic Laboratories’ “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, talks with outreach solutions strategists Ellen Dijkman Dulkes and Brianne Newton about key...

Best practices for managing outreach supplies - Insights

In this episode of Mayo Clinic Laboratories “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, talks with outreach solutions strategists Ellen Dijkman Dulkes and Brianne Newton about...

Safeguarding Specimen Integrity and Managing the Unexpected - Insights

In this episode of Mayo Clinic Laboratories’ “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, talks with Nikola Baumann, Ph.D., co-director of the Central Clinical Laboratory and...

Dissecting industry trends - Insights

In this episode of Mayo Clinic Laboratories’ “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, talks with outreach solutions strategists Ellen Dijkman Dulkes and Brianne Newton about...