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December 2022 - Transfusion Medicine - Insights
This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Transfusion Medicine.
Novel panel identifies toxins linked to asthma and GI diseases - Insights
Melissa Snyder, Ph.D., explains how Mayo Clinic Laboratories' EDN panel improves the evaluation of certain patients with asthma and autoimmune digestive disorders. EDN is the first laboratory test that provides a marker of...
Learn more about how direct ethanol biomarker testing at Mayo Clinic Laboratories provides heightened sensitivity and specificity to accurately assess alcohol use and alcohol use disorder.
December 2023 - Clinical Microbiology - Insights
This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Microbiology.
Raising the Bar on Newborn Screening Test Performance - Insights
Newborn screening panels that test for a variety of conditions are available in every state; however, test performance and response rate by each state are very different. Mayo Clinic's Biochemical Genetics Laboratory created the...
Preparation of Platelet-Poor Plasma for Special Coagulation Testing - Insights
In this months "Hot Topic," Christopher Desens, MLS(ASCP) discusses the preparation of platelet-poor plasma for coagulation testing.
Pathways Case Studies: June 2023 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for June include the following sub-specialties: Gastroenterology Pathology,...
hereditary_peripheral_neuropathies_testing_algorithm.pdf
Inherited neuropathy suspected; Insidious onsets progressive (years)* The following tests should be performed in all adult patients: HbA1c or glucose tolerance, vitamin B12, monoclonal proteins. Order PMPDD / PMP22 Gene, Large Deletion...
Autoimmune Encephalitis Diagnosis and Misdiagnosis - Insights
PACEIn this month’s “Virtual Lecture” Eoin Flanagan, M.D., B.Ch., reviews how to diagnose autoimmune encephalitis, what to watch that may suggest a different diagnosis, discuss neural autoantibodies interpretation and putting test results...
Alpha-gal testing [Test in Focus] - Insights
Joshua Bornhorst, Ph.D., associate director of Mayo Clinic's Clinical Immunoassay Lab, explains how humans can develop an allergy to the alpha-gal molecule, and he describes a new allergen antibody test that can be used to detect it. Dr....
Mayo Clinic Laboratory and pathology research roundup: July 25 - Insights
This week's research roundup feature: The clinical and molecular spectrum of ETV6 mutated myeloid neoplasms.
The diagnosis of Myeloproliferative Neoplasm (MPN) must include an integrated approach and combine the clinical findings with laboratory results. In our latest “Hot Topic,” Rong He, M.D., discusses the subclassification of MPNs and the use...
Pat Hlavka, CSP, Safety Coordinator at Mayo Clinic, discusses the most commonly cited Occupational Safety and Health Administration inspection findings for medical and diagnostic laboratories.
Case Studies in Laboratory Safety - Insights
PACE/State of FL - This webinar will provide a review of several real-life laboratory safety events. The presentation will outline the scenarios, the lessons learned and look at ways future incidents can be prevented. We will also discuss...
Pathways Case Studies: November 2023 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for November include the following sub-specialties: Cardiovascular Pathology,...
Pathways Case Studies: October 2023 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for October include the following sub-specialties Breast Pathology, Gynecological...
Alzheimer's Disease Testing - Mayo Clinic Laboratories
We have developed an innovative evaluation for Alzheimer's disease, which uses CSF biomarkers to achieve a high concordance with amyloid PET scan.
Acquired Neuropathy Diagnostic Algorithm
Acquired Neuropathy Diagnostic Algorithm
Prostate Health Index (phi) [Test in Focus] - Insights
Useful For Assessing the patient’s probability of having detectable prostate cancer when totalprostate specific antigen (PSA) concentrations are between
Orexin-A/Hypocretin-1 for the Diagnosis of Type 1 Narcolepsy [Test in Focus] - Insights
The standard test for the diagnosis of narcolepsy is the multiple sleep latency test (MSLT). The MSLT is a complex test to perform as well as to interpret. The orexin-A/hypocretin-1 test is a sensitive and specific alternative to the MSLT...
Staffing to Workload: Operational Needs - Insights
Mike Baisch, Systems Engineer at Mayo Clinic, discusses the mechanics of performing a staffing-to-workload analysis in the testing laboratories. There are three primary areas of focus with staffing needs: direct effort, indirect effort, and...
A novel testing approach for newly identified VEXAS syndrome - Insights
VEXAS syndrome is a severe autoinflammatory disease that results in a spectrum of rheumatologic and hematologic conditions. The underlying cause of newly identified VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome —...
August 2023 - Lab Genetics & Genomics - Insights
This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Laboratory Genetics and Genomics.
Pathways Case Studies: December 2023 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for December include the following sub-specialties: Cardiovascular Pathology and...
Mayo Clinic Laboratory and Pathology Research Roundup: May 14 - Insights
This week's research roundup feature: Despite advances in understanding the genetic abnormalities in myeloproliferative neoplasms (MPNs) and the development of JAK2 inhibitors, there is an urgent need to devise new treatment strategies,...
Pathways Case Studies: July 2020 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for July include the following sub-specialties: Bone and Soft Tissue & Pulmonary,...
December 2022 - Clinical Informatics - Insights
This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Informatics.
Testing for Streptococcus pneumoniae Antibodies - Insights
In this month's "Hot Topic," Melissa Snyder, Ph.D., identifies the clinical application of testing for Streptococcus pneumoniae polysaccharide antibodies and describes the tests available for measuring these antibodies.
Find out more about UBA1Q, a quantitative droplet digital polymerase chain reaction (ddPCR) assay that targets seven possible mutations that can occur in the UBA1 gene and help identify VEXAS syndrome.
Bobbi Pritt, M.D., Comments on Blacklegged Ticks in Minnesota Conservation Volunteer - Insights
Blacklegged ticks (also known as deer ticks) are turning up more frequently in Minnesota, and so are the diseases they carry. Bobbi Pritt, a parasitologist in the Department of Laboratory Medicine and Pathology at Mayo Clinic in Rochester,...
Mayo Clinic Laboratory and Pathology Research Roundup: December 26 - Insights
This week's research roundup feature: Histoplasma and Blastomyces antigen detection assays are commonly used diagnostic tools. However, a high level of cross-reactivity between these antigens prevents definitive pathogen identification by...
Direct Ethanol Biomarker Testing: PETH - Insights
Paul Jannetto, Ph.D., describes Mayo Clinic Laboratories' new direct biomarker test for alcohol consumption. PETH is a blood test with a window of detection of about two to four weeks — compared with five days for urine-based screening for...
RNA test identifies large B-cell lymphoma subtypes: Lisa Rimsza, M.D. - Insights
Lisa Rimsza, M.D., explains how Mayo Clinic Laboratories' unique PM3CX test can accurately determine subtypes of large B-cell lymphoma. Precise diagnosis is critical to choosing appropriate chemotherapy.
Mayo Clinic Laboratory and Pathology Research Roundup: Jan. 15 - Insights
This week’s Research Roundup highlights how the loss of FOXO1 cooperates with TMPRSS2-ERG overexpression to promote prostate tumorigenesis and cell invasion.
Week in Review: March 25 - Insights
Today's Highlights Include: e-changing kidney swap, climate change is making allergy season even worse, and a Minnesota Milestone: A day without COVID-19 deaths.
Pathways Case Studies: June 2022 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for June include the following sub-specialties: Dermatopathology, Gastroenterology...
Cardiovascular Events in Patients With or Without Coronary Artery Disease
A new type of blood test may help physicians identify which patients with and without evidence of coronary blockages are at risk for heart attacks and strokes. Even individuals with normal levels of low-density lipoprotein (LDL), known as...
Pathways Case Studies: April 2022 - Insights
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for April include the following sub-specialties: Bone and Soft Tissue Pathology,...
Alzheimer's Disease CSF Biomarkers - Insights
In this month's "Hot Topic," Alicia Algeciras, Ph.D., DABCC, and Joshua Bornhorst, Ph.D., DABCC, discuss Alzheimer's disease CSF biomarkers.
This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. This case sub-specialty is Renal.
Urinary ammonium testing - Insights
John Lieske, M.D., discusses Mayo Clinic Laboratories' urinary ammonium testing. A test that takes the guesswork out of determining acid base disorders by giving nephrologists a true understanding of a patient’s true urinary ammonium level.
QuantiFERON-TB Gold Plus - Insights
In this month’s “Hot Topic,” Elitza Theel, Ph.D. will discuss a new interferon-gamma release assay that can assist in the detection of individuals that are infected with tuberculosis.
Select Agents Module - Insights
Select Agents Module Expires: May 8, 2025 Overview This module reviews the characteristics of Select Agent organisms. Participants will read about Select
August 2023 - Clinical Chemistry - Insights
This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Chemistry.
Selecting Pathology Specimens for Solid Tumors Next-Generation Sequencing - Insights
In this month’s “Hot Topic,” Sounak Gupta, M.B.B.S., Ph.D., discusses selecting tissues and other tissue considerations for molecular testing. He also reviews tissue metrics and requirements, which differ based on test platforms. It is...
Mayo Clinic Laboratory and pathology research roundup: September 28 - Insights
This week's research roundup features: Effect of probiotics on incident ventilator-associated pneumonia in critically Ill patients: A randomized clinical trial.
Mayo Clinic Laboratory and pathology research roundup: May 17 - Insights
Top highlights include: Rapid exclusion of acute myocardial injury and infarction with a high sensitivity cardiac troponin T in the emergency department.
Copeptin [Test in Focus] - Insights
Joshua Bornhorst, Ph.D., gives an overview of the new Copeptin test available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing improves upon previous testing approaches, and what clinical...
This three-day virtual conference offered for just a few hours each day will offer the opportunity to learn techniques for managing burnout and ways to create a positive patient experience. Attendees will have the option to select from a...
October 2023 - Breast Pathology - Insights
This "Pathways" program provides an Anatomic Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Breast Pathology.