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acute_myeloid_leukemia_relapsed_with_previous_remission_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 08/2023 Acute Myeloid Leukemia: Relapsed with Previous Remission Algorithm YES YES NO NO Previously diagnosed acute myeloid leukemia (AML) More than 6...
autoimmune-paraneoplastic-dementia-evaluation-algorithm-spinal-fluid.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Dementia Evaluation Algorithm-Spinal Fluid ■ Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Spinal Fluid ■...
HIV Treatment Monitoring Algorithm
HIV Treatment Monitoring Algorithm
acute_tick-borne_disease_testing_algorithm.pdf
04/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Acute Tickborne Disease Testing Algorithm Order: SFGP / Spotted Fever Group Antibody, IgG and IgM, Serum Empiric treatment encouraged for high...
myeloproliferative_neoplasm_a_diagnostic_approach_to_bone_marrow_evaluation.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 08/2023 Myeloproliferative Neoplasm: A Diagnostic Approach to Bone Marrow Evaluation Clinical suspicion of myeloproliferative neoplasm Consistent with...
spinal-muscular-atrophy-testing-algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 02/2024 Spinal Muscular Atrophy Testing Algorithm SMNDX / Spinal Muscular Atrophy Diagnostic Assay, Deletion/Duplication Analysis, Varies Clinical suspicion...
Lyme Neuroborreliosis Diagnostic Algorithm.indd
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 10/2019 Neuroinvasive Lyme disease should be considered in patients, with exposure to ticks in a Lyme-endemic region, who present with 1 or more of the...
autoimmune-paraneoplastic-epilepsy-evaluation-algorithm-spinal-fluid.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Epilepsy Evaluation Algorithm-Spinal Fluid ■ Glutamic acid decarboxylase (GAD65) antibody assay ■ Antineuronal nuclear...
aggressive_b_cell_lymphoma_diagnostic_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 03/2022 Aggressive B-cell Lymphoma Diagnostic Algorithm Morphology: diffuse large B-cell lymphoma (DLBCL), high grade B-cell lymphoma (HGBCL), or Burkitt...
porphyria__cutaneous__testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Porphyria (Cutaneous) Testing Algorithm Symptom: Skin manifestations restricted to sun-exposed areas Symptoms: ■ Edema ■ Sun-induced erythema ■...
amyloidosis__familial__test_algorithm.pdf
12/2022© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Amyloidosis (Familial) Test Algorithm* *Interpretive report provided for all tests in this algorithm. Clinical findings suggestive of familial...
lynch_syndrome_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 03/2024 Lynch Syndrome Testing Algorithm Pathogenic variant identified Testing in family member was negative or variant of uncertain significance...
autoimmune-paraneoplastic-gastrointestinal-dysmotility-evaluation-algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Gastrointestinal Dysmotility Evaluation Algorithm ■ PCA-2 IFA titer■ ANNA-1 antibody by immunoblot ■ ANNA-2 antibody...
parasitic_investigation_of_stool_specimens_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 06/2023 Parasitic Investigation of Stool Specimens Algorithm Patients with watery diarrhea Risk factors for parasitic infection include: ■ AIDS ■ ≤5 years...
fabry_disease_newborn_screen-positive_follow-up.pdf
08/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Fabry Disease: Newborn Screen-Positive Follow-up False-positive newborn screen Disease-causing variant identified Newborn screen result: Decreased...
HIV-1 Ab Negative HIV-2 Ab Negative HIV-1 RNA Negative HIV-2 RNA Negative HIV-1 Ab Negative HIV-2 Ab Indeterminate HIV-1 RNA Negative HIV-2 RNA Positive HIV-1 Ab Indeterminate HIV-2 Ab Indeterminate HIV-1 RNA Positive HIV-2 RNA...
01/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Steroid Pathways Mineralocorticoids CYP17A1 = Cytochrome P450 Family 17 Subfamily A Member 1 HSD3B1/HSD3B2 = 3ß Hydroxysteroid...
celiac_disease_gluten-free_cascade_test_algorithm.pdf
05/2022© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. STOP No further testing required Celiac Disease Gluten-Free Cascade Test Algorithm Patient following a gluten-free diet with uncertain or...
ugt1a1_test-ordering_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 03/2024 UGT1A1 Test-Ordering Algorithm Indication for UGT1A1 testing Drug metabolism assessment for drug toxicity Order UGTFZ / UDP-Glucuronosyltransferase...
HCV Treatment_(Interferon-Free).indd
05/2019© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Chronic Hepatitis C Treatment and Monitoring Algorithm: Direct Antiviral Agent (DAA) Combination * www.hcvguidelines.org Treatment failure STOP...
gastric_malt_lymphoma_diagnostic_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 01/2022 Questionable gastric MALT lymphoma diagnostic biopsy Diagnosis: Negative for lymphoma Diagnostic or suspicious for other subtype of lymphoma Follow...
MAYO CLINIC LABORATORIES Newborn Screen Follow-up for Gaucher Disease GBA activity - decreased Glucopsychosine - elevated Gaucher disease confirmed Referral to Genetics Specialist Newborn screen result: decreased beta-glucosidase*...
mycobacterium-and-nocardia-culture-algorithm.pdf
02/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Mycobacterium and Nocardia Culture Algorithm Tissue Processing Mycobacterium Culture, Concentration CTB / Mycobacteria and Nocardia Culture ■...
autoimmune-paraneoplastic-myelopathy-evaluation-algorithm-spinalfluid.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Myelopathy Evaluation Algorithm-Spinal Fluid ■ Amphiphysin antibody by immunoblot ■ Amphiphysin antibody by IF titer...
ganglioside_antibody_panel_algorithm.pdf
08/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Ganglioside Antibody Panel Algorithm IgG Monosialo GM1 titer is performed IgM Monosialo GM1 titer is performed IgG Disialo GD1b titer is...
autoimmune-paraneoplastic-dementia-evaluation-algorithm-serum.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Dementia Evaluation Algorithm-Serum Glutamic acid decarboxylase (GAD65) antibody assay ■ Antineuronal nuclear...
pediatric-autoimmune-encephalopathy-central-nervous-system-disorders-evaluation-algorithm-serum.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Pediatric Autoimmune Encephalopathy/ Central Nervous System Disorders Evaluation Algorithm-Serum ■ ANNA-1 immunoblot ■ ANNA-2 immunoblot ■ ANNA-1 IF...
inherited_motor_neuron_disease_testing_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 12/2022 Spinal muscular atrophy (SMA) phenotype -SMA types 1-4 Order SMNDX / Spinal Muscular Atrophy Diagnostic Assay by Deletion/ Duplication...
newborn-screen-elevated-c8-acylcarnitine-lesser-elevations-c6-c10-acylcarnitines.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 08/2023 Newborn screen results: ■ Elevated C8 acylcarnitine ■ Lesser elevations of C6 and C10 acylcarnitines Perform: Glucose, electrolytes, blood gas, liver...
newborn_screen_follow-up_for_mucopolysaccharidosis_type_ii.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 02/2024 Newborn screening results: ■ Decreased iduronate-2-sulfatase activity ■ Elevated dermatan and heparan sulfate Order the following: ■ I2SWB /...
newborn-screen-follow-up-acid-sphingomyelinase-deficiency.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 03/2023 Newborn screen result: decreased sphingomyelinase with or without abnormal 2nd-tier testing Order: ■ ASMW / Acid Sphingomyelinase, Leukocytes AND 1...
sequential-maternal-serum-screening-testing-algorithm.pdf
03/2023© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Sequential Maternal Serum Screening Testing Algorithm Diagnostic testing should be offered Screen-positive: results...
newborn_screen_follow-up_for_severe_combined_immunodeficiency_syndrome__scid_.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 02/2024 Decreased T-cell receptor excision circles on newborn screening test Perform: ■ CBC with differential ■ TBBS / Quantitative Lymphocyte Subsets: T,...
newborn_screen_follow-up_for_glucose-6-phosphate_dehydrogenase__g-6-pd__deficiency.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 03/2024 Decreased glucose-6-phosphate dehydrogenase (G6PD) Not G6PD deficiency. In infants with hyperbilirubinemia, consider repeat G6PD enzyme testing...
autoimmune-paraneoplastic-epilepsy-evaluation-algorithm-serum.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Epilepsy Evaluation Algorithm-Serum ■ ANNA-1 antibody by immunoblot ■ ANNA-2 antibody by immunoblot ■ ANNA-2...
newborn_screen_follow-up_for_krabbe_disease_galactocerebrosidase.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 08/2024 Newborn Screen Follow-up for Krabbe Disease: Galactocerebrosidase Newborn screening result: decreased galactocerebrosidase (GALC) ■ GALC...
lysosomal_storage_disorders_screen_interpretive_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 04/2022 Lysosomal Storage Disorders Screen Interpretive Algorithm One of the following: ■ α-Mannosidosis ■ Aspartyglucosaminuria ■ β-Mannosidosis ■ Gaucher...
firstline-screening-autoimmune-liver-disease-algorithm.pdf
05/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. First-Line Screening for Autoimmune Liver Disease Algorithm Consider: ■ PBC2 / SP100 and GP210 Antibodies, IgG, Serum ■ LKM / Liver/Kidney...
Malaria Laboratory Testing.indd
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 04/2021 Malaria Laboratory Testing Algorithm 1 Malaria can be a rapidly fatal disease, particularly when due to Plasmodium falciparum, and less commonly...
autoimmune-paraneoplastic-movement-disorder-evaluation-algorithm-serum.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Movement Disorder Evaluation Algorithm – Serum ■ GFAP alpha subunit antibody by CBA ■ GFAP alpha subunit antibody by...
chimerism-recipient_germline_testing_algorithm.pdf
01/2022© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Chimerism–Recipient Germline Testing Algorithm Results are reported as “Performed”. Final report will be issued after testing for engraftment...
T800 MC4091-67CH MC4091-67CH.indd 1-2 11/14/2017 9:23:30 AM MC4091-67CH.indd 3-4 11/14/2017 9:23:30 AM
MCL Blood Spot Collections Instructions Flyer MC4091135
MCL Blood Spot Collections Instructions Flyer Blood Spot Collection Instructions Instructions Blood Collection Heelstick Fingerstick minutes place warmer
MCL - Blood Spot Collection Instructions (Spanish) - Brochure - MC4091-67SP
MCL - Blood Spot Collection Instructions (Spanish) - Brochure
testing_algorithm_for_the_screening_and_diagnosis_of_hepatitis_c.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 02/2022 Hepatitis C: Testing Algorithm for Screening and Diagnosis HCVQN / Hepatitis C Virus (HCV) RNA Detection and Quantification by Real-Time Reverse...
bile_acid-associated_tests_ordering_guide.pdf
Bile Acid-Associated Tests Ordering Guide Evaluation of Bowel Dysfunction Use to identify individuals with bile acid diarrhea (1) For screening order 7AC4 / 7AC4, Bile Acid Synthesis, Serum (2) For diagnosis order BAMRP / Bile...
assessment-dengue-virus-infection.pdf
08/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Assessment for Dengue Virus Infection Testing for dengue virus infection should be considered in individuals who meet both of the following...
pediatric-autoimmune-encephalopathy-cns-disorders-evaluation-algorithm-spinal-fluid.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 05/2024 Pediatric Autoimmune Encephalopathy/Central Nervous System Disorders Evaluation Algorithm-Spinal Fluid PCDEC / Pediatric Autoimmune...
celiac_disease_serology_cascade_test_algorithm.pdf
© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Interpretive report includes: ■ Serum IgA ■ Tissue transglutaminase antibody, IgA ■ Endomysial antibody, IgA ■ Gliadin (deamidated) antibody, IgA ■...
demyelinating-neuropathy-evaluation-algorithm.pdf
08/2024© Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. Demyelinating Neuropathy Evaluation Algorithm Neurofascin-155 IgG4 IgG Monosialo GM1 titer is performed IgM Monosialo GM1 titer is performed IgG...