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Unveiling a novel hemoglobinopathy classification - Insights
In a recent discovery by Mayo Clinic Laboratories, a novel hemoglobinopathy category was identified and termed epsilon gamma thalassemia. The first instance of the disorder was found in 2017 when an obstetric patient underwent a routine...
Mayo Clinic’s cardiac (CV) remote monitoring service uses the compact MoMe Kardia cardiac monitoring device that yields a continuous, 24/7 stream of a patient’s ECG and motion data, no matter their location. Any troubling or burgeoning...
Mayo Clinic Laboratories offers a robust menu of biomarker testing to assess liver disease related to nonalcoholic and alcoholic causes. These include FibroTest-ActiTest, a first-line screening assay that uses two diagnostic scores based on...
Hepatocellular carcinoma - Insights
Hepatocellular carcinoma (HCC) is the third leading cause of death from cancer in the world. While HCC can be effectively treated in its early stages, most patients are not diagnosed until they are symptomatic and at higher grades and...
Viral Hepatitis Testing - Mayo Clinic Laboratories
At Mayo Clinic, we utilize an algorithmic approach to testing that takes the guesswork out of test ordering to focus on proper test utilization, saving your institution time and money.
Diagnostic Guidelines for Celiac Disease - Insights
In this "Hot Topic," Melissa Snyder, Ph.D., provides a brief review of published guidelines for the diagnosis of celiac disease, with a specific focus on the role of laboratory testing.
Diagnostic Testing Algorithms for Celiac Disease - Insights
In this month's "Hot Topic," Melissa Snyder, Ph.D., co-director of the antibody immunology laboratory at Mayo Clinic, discusses celiac disease and the role of diagnostic testing algorithms.
Diagnosis and inflammation monitoring - Insights
Patients with symptoms that arouse clinical suspicion of either inflammatory bowel disease (IBD) or irritable bowel syndrome (IBS) are both common and tough to differentiate.
Exocrine pancreatic insufficiency - Insights
Stool testing is a critical component of diagnosing exocrine pancreatic insufficiency (EPI), and Mayo Clinic Laboratories offers several tests to help clinicians evaluate these patients. A 48- or 72-hour stool fecal fat test is useful for...
Malabsorption panel - Insights
Mayo Clinic Laboratories, which is integrated with the clinical gastroenterology practice at Mayo Clinic, understands the worry patients and their loved ones feel while awaiting test results. To expedite and streamline the diagnostic...
Bile acid malabsorption - Insights
Chronic diarrhea and abdominal pain can be caused by many conditions, including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), Celiac disease, infectious GI pathogens, and malignancy. When other causes of chronic diarrhea...
Disaccharidase deficiency - Insights
Disaccharidases are enzymes that break down complex sugars, such as lactose, into simple sugars, like glucose, so the nutrients can be absorbed in the intestine. Patients with disaccharidases deficiencies in the duodenum can experience...
Autoimmune Liver Disease Testing - Mayo Clinic Laboratories
Our panel evaluates smooth muscle antibodies (SMA), antinuclear antibodies (ANA), and antimitochondrial antibodies (AMA) for patients with suspected autoimmune liver disease, specifically type 1 AIH or PBC or with liver disease of unknown...
Benign Hematology Testing - Mayo Clinic Laboratories
Our metabolic hematology laboratory is dedicated to providing accurate diagnoses and interpretations with an emphasis on clinical significance for your patients.
Browse our menu of MayoComplete next-generation sequencing assays which are designed to identify a growing list of hematological cancers.
Learn about our full suite of leukemia testing protocols, including includes flow cytometry, chromosome, FISH, and molecular testing.
Cytogenetic Testing for Pediatric Patients With Hematologic Malignancies - Insights
In this month's "Hot Topic," Patricia Greipp, D.O., discusses fluorescence in situ hybridization, or FISH testing, particularly related to pediatric patients with hematologic malignancies.
Coagulation Disorders - Mayo Clinic Laboratories
Our special coagulation laboratory has been at the forefront of patient-centered and value-based diagnostic laboratory testing, research, and patient management for nearly 90 years.
Monogenic IBD Testing - Mayo Clinic Laboratories
Monogenic inflammatory bowel disease (IBD) refers to a diverse spectrum of rare genetic disorders that present with intestinal inflammation. The majority of patients with monogenic IBD, unlike those with polygenic IBD, show symptoms before...
Genetic liver disease - Insights
Identifying underlying genetic disorders plays an important role in the treatment and care of patients with liver disease. Appropriate use of screening tests in routine clinical practice can rule out possible causes of liver disease and...
Helicobacter pylori, or H. pylori, is one of the world’s most common chronic bacterial infections. Estimated to impact 4.4 billion individuals globally, H. pylori affects 35% to 89% of children, depending the on the geographic region in...
Featuring a full menu of advanced sequencing assays, Mayo Clinic Laboratories’ genetic test offerings for early-onset gastrointestinal disorders can provide diagnostic clarity that enables customized care.
A worldwide increase of the incidence of early-onset pediatric inflammatory bowel disease means more children than ever are diagnosed and treated for life-altering IBD diagnoses. However, not all children suspected of early-onset IBD have...
Mayo Clinic MASSFIX - Insights
Learn more about matrix-assisted laser desorption/ionization-time of flight mass spectrometry and the identification of plasma cell disorders.
Lab Medicine Rounds Archives - Insights
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Explore how Mayo Clinic Laboratories’ focused myositis specific antibody (MSA) panel equips healthcare professionals with individualized insights to reduce diagnostic uncertainty and assist with the selection of tailored treatments for...
Browse our full menu of individual tests and panels that aid in the diagnosis of tick-borne diseases.
Anti-Platelet Factor 4 Antibody-Mediated Prothrombotic Syndromes - Insights
PACE / State of FLIn this month's "Virtual Lecture," Anand Padmanabhan provides a general overview and science in the field related to heparin-induced thrombocytopenia (HIT), vaccine-induced thrombotic thrombocytopenia (VITT), and...
Heparin Induced Thrombocytopenia (HIT) and the Role of Serotonin Release Assay (SRA) - Insights
In this month's "Hot Topic," Rajiv Pruthi, M.B.B.S., discusses heparin induced thrombocytopenia (HIT), approach diagnosis, and the role of the functional serotonin release assay (SRA).
Multiomics: A new model for identifying biomarkers to predict severe COVID-19 outcomes - Insights
In a groundbreaking study, Mayo Clinic investigators have developed a multiomic molecular method to predict clinical COVID-19 (SARS-CoV-2) outcomes better than traditional cytokines. Using a machine-learning-based prediction model, the team...
Rapidly progressive dementia - Insights
Mayo Clinic Laboratories’ first-in-class testing for rapidly progressive dementia and Creutzfeldt-Jakob disease uses a sensitive and specific seed amplification assay that detects and identifies prion proteins in CSF alongside a clinically...
New tests launched in August - Insights
In August 2022, Mayo Clinic Laboratories announced thirty-two new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Understanding the difference between benign and malignant adrenal tumors has alway been difficult; this new assay will assist with this medical challenge.
Mayo Clinic Laboratories releases new, first-to-U.S.-market pregnancy risk assessment - Insights
Mayo Clinic Laboratories now offers the first preeclampsia-specific test (Mayo ID: PERA) that can be used to stratify patients into low or high-risk categories, indicating whether a patient is at risk for developing preeclampsia with severe...
Northeast winter storm - Insights
A winter storm is occurring in the Northeast which may impact specimen transport. The winter storm is expected to spread snow, strong winds, and create possible blizzard conditions which could impact courier pickups and route delays. We are...
Monitoring Hurricane Debby - Insights
As Hurricane Debby moves through the Southeast United States (Florida, Georgia, South Carolina, North Carolina, and Virginia), we continue to monitor and track the situation with our logistics partners to minimize challenges. Clients in the...
Monitoring Tropical Storm Francine - Insights
Tropical Storm Francine is active in the Gulf of Mexico and is expected to develop into a hurricane. These weather conditions may impact areas in the United States, including Alabama, Arkansas, Louisiana, Mississippi, Tennessee, and Texas....
Improvements to downtime process, form provide clarity for clients - Insights
The downtime process and form have been improved to provide clear guidance on the steps clients should take during downtime.
Monitoring Tropical Storm Helene - Insights
Tropical Storm Helene is approaching the Florida Gulf Coast and is expected to become a hurricane. These weather conditions may impact areas in the United States, including Alabama, Florida, Georgia, and South Carolina. We continue to...
Independence Day Specimen Shipping Guidelines and Schedule - Insights
Mayo Clinic Laboratories' specimen pickup and delivery schedules will be altered due to the upcoming July 4th holiday. To ensure specimen stability and prevent delays, follow the guidelines outlined below for domestic clients and...
Dr. Morice Shares Trends and Predictions for 2025 - Insights
The healthcare and diagnostics landscape is poised for transformative changes driven by technological advancements and evolving market dynamics.
Dr. Matt Binnicker sheds light on new Arcturus COVID-19 variant - Insights
Matthew Binnicker, Ph.D., director of Mayo Clinic’s Clinical Virology Laboratory, provides insight on the newest COVID-19 subvariant – XBB.1.16, also known as “Arcturus.”
A team of researchers has confirmed that neutralizing monoclonal antibody (nMAb) therapies are associated with reduced risk of adverse outcomes of COVID-19 in high-risk populations. The cohort study, published in JAMA, included more than...
Visit Mayo Clinic Laboratories at the APA Annual Meeting - Insights
Visit Mayo Clinic Laboratories at booth #2047 to learn about our comprehensive therapeutics test offerings. Developed by board-certified experts in clinical chemistry, molecular, and toxicology testing, our testing is designed to detect and...
Mayo Clinic Laboratories and Amprion, a global leader advancing diagnosis of neurodegenerative disorders through seed amplification testing, today announced a collaboration to expand access to Amprion's SAAmplify–αSYN (CSF) test across the...
Krabbe disease added to federal newborn screening panel - Insights
Thanks to advocacy work by a group of medical experts, including some from Mayo Clinic, the U.S. Department of Health and Human Services now recommends all states screen for infantile Krabbe disease to help save newborn lives.
Find out how our hereditary cancer panels use next-generation sequencing to evaluate dozens of genes associated with cancer risk.
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Mayo Clinic Labs @Work: Dr. Vanda Lennon - Insights
A pioneering researcher, Dr. Vanda Lennon has spent five decades delving into questions of neuroimmunology. Today, she continues that work as director of the Neuroimmunology Research Laboratory in Mayo Clinic’s Department of Laboratory...
Mayo Clinic Labs @Work: Tim Brantner - Insights
Before he arrived at Mayo Clinic, Tim Brantner worked for a variety of organizations outside of health care. He joined Mayo Clinic Laboratories 14 years ago to help tell the labs’ story.