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Mayo Clinic Laboratory and Pathology Research Roundup: March 26 - Insights

This week’s Research Roundup highlights the development of a microscopic colitis disease activity index.

Rondell Graham, M.B.B.S., Outlines Occult Cancer Workup in CAP Today - Insights

Rondell Graham, M.B.B.S., an anatomic and molecular consultant at Mayo Clinic, co-led a molecular oncology tumor board session at CAP19, and subsequently spoke with CAP Today.

Elitza Theel, Ph.D., Explains New Lyme Disease Testing - Insights

Elitza Theel, Ph.D., Director of the Infectious Diseases Serology Laboratory, Co-Director of the Vector-Borne Diseases Laboratory, and Associate Professor of Laboratory Medicine and Pathology, was recently interviewed by CAP Today about new...

1964: Orange and Blue Calendar becomes Official #ThrowbackThursday - Insights

From surgical procedures to committee meetings, activities at Mayo Clinic are scheduled around “orange days” and “blue days.” How and why did those colors come to be?

Mayo Clinic Laboratory and Pathology Research Roundup: June 4 - Insights

This week’s Research Roundup highlights isolated hepatic non-obstructive sinusoidal dilatation, a 20-year single center experience.

Mayo Clinic Laboratory and pathology research: May 3 - Insights

Featured abstract: An overview of the clinical presentation, pathology, and the current therapeutic approach of the main representative disorders in the spectrum of glomerulonephritis.

Mayo Clinic Laboratory and pathology research roundup: April 26 - Insights

Top highlights include: Arrhythmia variant associations and reclassifications in the eMERGE-III sequencing study.

Mayo Clinic Laboratory and pathology research roundup: May 17 - Insights

Top highlights include: Rapid exclusion of acute myocardial injury and infarction with a high sensitivity cardiac troponin T in the emergency department.

Mayo Clinic Laboratory and pathology research roundup: May 10 - Insights

Top highlights include: Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse.

Mayo Clinic Laboratory and Pathology Research Roundup: March 19 - Insights

This week’s Research Roundup highlights the analysis of cell-free DNA to assess risk of tumoremia following endoscopic ultrasound fine-needle aspiration of pancreatic adenocarcinomas.

Mayo Clinic Laboratory and pathology research roundup: November 23 - Insights

This week’s research roundup features: The temporal onset of the core features in dementia with Lewy bodies.

Mayo Clinic Laboratory and pathology research roundup: November 2 - Insights

This week’s research roundup features: Phase II randomized trial of transoral surgery and low-dose intensity Modulated radiation therapy in resectable p16+ locally advanced oropharynx cancer: An ECOG-ACRIN cancer research group trial...

Mayo Clinic Laboratory and Pathology Research Roundup: Feb. 5 - Insights

This week’s Research Roundup highlights cryptogenic cirrhosis and sitosterolemia, a treatable disease if identified but fatal if missed.

Mayo Clinic Laboratory and pathology research roundup: May 24 - Insights

Top highlights include: Monoclonal and oligoclonal anti-Platelet Factor 4 antibodies mediate VITT.

Mayo Clinic Laboratory and pathology research roundup: June 14 - Insights

Featured Abstract: Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities.

Mayo Clinic Laboratory and pathology research roundup: May 31 - Insights

Featured abstract: Substance use screening in transplant populations.

Mayo Clinic Laboratory and pathology research roundup: October 26 - Insights

This week’s research roundup features: Proceedings from the ice hockey summit III: Action on concussion.

Paula Santrach, M.D., Receives 2017 ACMQ Founders Award - Insights

Paula Santrach, M.D., Consultant in the Division of Transfusion Medicine and Associate Professor of Laboratory Medicine and Pathology at Mayo Clinic, was named the recipient of the 2017 American College of Medical Quality (ACMQ) Founders...

Mayo Clinic Laboratory and pathology research roundup: April 4 - Insights

This Feature Includes: Utility of Follow-up COVID-19 Antigen Tests After Acute SARS-CoV-2 Infection Among Healthcare Personnel.

Amy Clayton, M.D., Appointed Anatomic Pathology Division Chair - Insights

The Department of Laboratory Medicine and Pathology is pleased to announce the appointment of Amy Clayton, M.D., as the new Chair of the Division of Anatomic Pathology at Mayo Clinic in Rochester.

Bobbi Pritt, M.D., Featured on Mayo Clinic Radio to Discuss Lyme Disease Predictions for 2017 - Insights

On the April 22 broadcast of Mayo Clinic Radio, co-hosts Tracy McCray and Tom Shives, M.D., spoke with Bobbi Pritt, M.D., Director of the Clinical Parasitology Laboratory, about an update on Lyme disease predictions for 2017.

Rosalind Sharain, M.D., and Nooshin Karamzadeh Dashti, M.D., Named Surgical Pathology Chief Fellows - Insights

Rosalind Sharain, M.D., and Nooshin Karamzadeh Dashti, M.D., have been named Chief Fellows for the Surgical Pathology Fellowship Program for the academic year 2017–18.

Mayo Clinic Laboratory and pathology research roundup: December 20 - Insights

This week's research roundup features: Expanding the platelet inventory to mitigate the impact of severe shortages

Mayo Clinic Laboratory and pathology research roundup: February 7 - Insights

This week's Research Roundup features: Maintenance of remission and risk of relapse in Myeloperoxidase-positive ANCA-associated Vasculitis with kidney involvement.

Mayo Clinic Laboratory and pathology research roundup: March 21 - Insights

This week's Research Roundup features: Performance comparisons of methylation and structural variants from low-input whole-genome methylation sequencing.

Mayo Clinic Laboratory and pathology research roundup: April 4 - Insights

This week's Research Roundup features: Fatal Human Rabies Infection with Suspected Host-mediated Failure of Post-Exposure Prophylaxis Following a Recognized Zoonotic Exposure-Minnesota, 2021.

Mayo Clinic Laboratory and pathology research roundup: April 25 - Insights

This week's Research Roundup feature: Deficiency of the CD155-CD96 immune checkpoint controls IL-9 production in giant cell arteritis.

Mayo Clinic Laboratory and pathology research roundup: March 28 - Insights

This week's Research Roundup features: Elementary overview of heavy metals.

Mayo Clinic Laboratory and pathology research roundup: March 8 - Insights

This week’s research roundup features: Androgen deprivation therapy use and duration with definitive radiotherapy for localized prostate cancer: an individual patient data meta-analysis.

Week in Review: May 20 - Insights

Today's highlights include: US at risk of COVID-19 drug shortages this summer, Rochester startup Vyriad developing cancer-fighting viruses, and CDC expresses concern about possibility of undetected monkeypox spread in U.K.

Week in Review: May 13 - Insights

Today's highlights include: Pandemic gets tougher to track as COVID testing plunges, Rochester hospitals score top grades in safety, and Mayo Clinic breaks ground on $155M Minnesota hospital expansion.

Mayo Clinic Laboratory and pathology research roundup: December 28 - Insights

This week’s research roundup features: Risk of late-onset breast cancer in genetically predisposed women.

Mayo Clinic Laboratory and pathology research roundup: November 30 - Insights

This week’s research roundup features: Tumor junction burden and antigen presentation as predictors of survival in mesothelioma treated with immune checkpoint inhibitors.

Eoin Flanagan, M.B., B.Ch., explains autoimmune encephalitis misdiagnosis in JAMA Neurology - Insights

Education on this topic decreases misdiagnosis and the possibility of misinterpreting the comments provided by the reporting laboratories.

New tests launched in September - Insights

In September 2022, Mayo Clinic Laboratories announced ten new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

New tests launched in November - Insights

Mayo Clinic Laboratories launched the following three tests in November.

Chromium and Cobalt Testing [Test in Focus] - Insights

Chromium and cobalt blood tests are used to monitor exposure to these elements. Both of these elements are naturally occurring and widely distributed in the environment. Previously, serum samples were collected and used to monitor patients...

Alpha-gal testing [Test in Focus] - Insights

Joshua Bornhorst, Ph.D., associate director of Mayo Clinic's Clinical Immunoassay Lab, explains how humans can develop an allergy to the alpha-gal molecule, and he describes a new allergen antibody test that can be used to detect it. Dr....

MDM2 gene amplification [Test in Focus] - Insights

William Sukov, M.D., provides an overview of the MDM2 gene amplification assay — a test that looks for amplification of the MDM2 gene region on chromosome 12q. He reviews when this test should be ordered, how it compares to other test...

B-cell lymphoblastic leukemia monitoring for minimal residual disease [Test in Focus] - Insights

Min Shi, M.D., Ph.D., a hematologist and co-director of Mayo Clinic's Flow Cytometry Laboratory, explains recent updates to the B-cell lymphoblastic leukemia minimal residual disease flow cytometry assay. This test is used to identify...

Mayo Clinic Laboratory and pathology research roundup: September 12 - Insights

This week's research roundup feature: Activated mast cells in periprosthetic joint infection-associated tissue.

Mayo Clinic Laboratory and pathology research roundup: June 6 - Insights

This week's research roundup feature: Utilizing mass spectrometry to detect and isotype monoclonal proteins in urine: Comparison to electrophoretic methods.

Mayo Clinic Laboratory and pathology research roundup: August 15 - Insights

This week's research roundup feature: Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis.

Mayo Clinic Laboratory and pathology research roundup: July 4 - Insights

This week's research roundup feature: Emergence of inducible macrolide resistance in mycobacterium chelonae due to broad-host-range plasmid and chromosomal variants of the novel 23S rRNA methylase gene, erm(55).

Mayo Clinic Laboratory and pathology research roundup: July 25 - Insights

This week's research roundup feature: The clinical and molecular spectrum of ETV6 mutated myeloid neoplasms.

Mayo Clinic Laboratory and pathology research roundup: May 9 - Insights

This week's research roundup feature: Proprotein Convertase Subtilisin/Kexin Type 6 (PCSK6) is a likely antigenic target in membranous nephropathy and nonsteroidal anti-inflammatory drug use.

Necrotizing Autoimmune Myopathy [Test in Focus] - Insights

Necrotizing autoimmune myopathy (NAM) is a serious but rare muscle disease strongly associated with autoantibodies to either the protein signal recognition particle (SRP) or the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase...

Mayo Clinic Laboratory and pathology research roundup: April 19 - Insights

Top highlights include: Advances in neuroimaging for brain charts for the human lifespan.