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Diagnosis and inflammation monitoring - Insights
Patients with symptoms that arouse clinical suspicion of either inflammatory bowel disease (IBD) or irritable bowel syndrome (IBS) are both common and tough to differentiate.
Pancreatic Elastase - Insights
Puanani Hopson, D.O., a Mayo Clinic pediatric gastroenterologist, explains the pancreatic elastase test — a screening test that can be useful when symptoms point to the possibility of exocrine pancreatic insufficiency. Dr. Hopson reviews...
Exocrine pancreatic insufficiency - Insights
Stool testing is a critical component of diagnosing exocrine pancreatic insufficiency (EPI), and Mayo Clinic Laboratories offers several tests to help clinicians evaluate these patients. A 48- or 72-hour stool fecal fat test is useful for...
Malabsorption panel - Insights
Mayo Clinic Laboratories, which is integrated with the clinical gastroenterology practice at Mayo Clinic, understands the worry patients and their loved ones feel while awaiting test results. To expedite and streamline the diagnostic...
Bile acid malabsorption - Insights
Chronic diarrhea and abdominal pain can be caused by many conditions, including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), Celiac disease, infectious GI pathogens, and malignancy. When other causes of chronic diarrhea...
Disaccharidase deficiency - Insights
Disaccharidases are enzymes that break down complex sugars, such as lactose, into simple sugars, like glucose, so the nutrients can be absorbed in the intestine. Patients with disaccharidases deficiencies in the duodenum can experience...
Testing Options for Patients with Chronic Diarrhea: A Focus on Bile Acid Malabsorption - Insights
A new serum test for bile acid malabsorption. Descriptions illustrate how the test can be used as a screening test and as a tool for therapeutic action.
Autoimmune Gastrointestinal Dysmotility Evaluation [Test in Focus] - Insights
Divyanshu (Div), Dubey, M.B.B.S, gives an overview of the new Autoimmune Gastrointestinal Dysmotility Evaluation available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing compares to...
Updates Streamline Autoimmune Neurology Testing: Anastasia Zekeridou, M.D., Ph.D. - Insights
Anastasia Zekeridou, M.D., Ph.D., explains how Mayo Clinic Laboratories' updated panels and methodology boost the accuracy and efficiency of testing for three autoimmune neurology biomarkers. Early diagnosis is key to managing debilitating...
Comprehensive panel boosts GIST diagnosis sensitivity - Insights
Rondell Graham, M.B.B.S., describes Mayo Clinic Laboratories' new assay for gastrointestinal stromal tumors, or GIST. The panel covers multiple mutations, to better inform diagnosis and treatment options.
Hepatitis C Virus Genotypic Antiviral Drug Resistance [Test in Focus] - Insights
Joseph Yao, M.D., gives an overview of this new test available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing improves upon other testing approaches, and what clinical action can be...
Autoimmune Liver Disease Testing - Mayo Clinic Laboratories
Our panel evaluates smooth muscle antibodies (SMA), antinuclear antibodies (ANA), and antimitochondrial antibodies (AMA) for patients with suspected autoimmune liver disease, specifically type 1 AIH or PBC or with liver disease of unknown...
Mayo Clinic Laboratory and Pathology Research Roundup: May 7 - Insights
This week’s Research Roundup highlights how fasting blood-glucose levels provide estimate of duration and progression of pancreatic cancer before diagnosis.
Mayo Clinic Laboratory and Pathology Research Roundup: March 5 - Insights
This week's research roundup feature: Variants of uncertain significance (VUSs) in BRCA2 are a common result of hereditary cancer genetic testing. While more than 4,000 unique VUSs, comprised of missense or intronic variants, have been...
Mayo Clinic Laboratory and Pathology Research Roundup: March 12 - Insights
This week's research roundup feature: C3 glomerulopathy (C3G) is a rare disease resulting from dysregulation of the alternative pathway of complement. C3G includes C3 glomerulonephritis (C3GN) and dense deposit disease (DDD), both of which...
Mayo Clinic Laboratory and Pathology Research Roundup: April 2 - Insights
This week's research roundup feature: Follicular lymphoma (FL) is an indolent non-Hodgkin lymphoma of germinal center origin, which presents with significant biologic and clinical heterogeneity. Using RNA-seq on B cells sorted from 87 FL...
Mayo Clinic Laboratory and Pathology Research Roundup: April 30 - Insights
This week's research roundup feature: Patients with dementia with Lewy bodies (DLB) may have Alzheimers disease (AD) pathology that can be detected by plasma biomarkers. Our objective was to evaluate plasma biomarkers of AD and their...
Mayo Clinic Laboratory and Pathology Research Roundup: April 23 - Insights
This week's research roundup feature: Only 20 percent of renal and bladder cancer patients will show a significant response to immune checkpoint inhibitor (ICI) therapy, and no test currently available accurately predicts ICI response. We...
Mayo Clinic Laboratory and Pathology Research Roundup: April 9 - Insights
This week's research roundup feature: Intrathecal delivery of autologous culture-expanded adipose tissue-derived mesenchymal stem cells (AD-MSC) could be utilized to treat traumatic spinal cord injury (SCI). This Phase I trial...
Mayo Clinic Laboratory and Pathology Research Roundup: April 16 - Insights
This week's research roundup feature: R0 resection and radiation therapy have been associated with improved overall survival (OS) in patients with thymic carcinoma (TC). Here, we analyzed which subgroups of patients derive the greatest...
Mayo Clinic Laboratory and Pathology Research Roundup: March 26 - Insights
This week's research roundup feature: Implant-associated infections (IAIs) pose serious threats to patients and can be associated with significant morbidity and mortality. These infections may be difficult to diagnose due, in part, to...
Mayo Clinic Laboratory and Pathology Research Roundup: March 19 - Insights
This week's research roundup feature: The revised 4th edition of the World Health Organization (WHO4R) classification lists myelodysplastic syndromes with ring sideroblasts (MDS-RS) as a separate entity with single lineage (MDS-RS-SLD) or...
Mayo Clinic Laboratory and Pathology Research Roundup: May 7 - Insights
This week's research roundup feature: To standardize international normalized ratio (INR) measurements and improve data integrity by enabling electronic result transmission for warfarin monitoring, two point-of-care (POC) devices were...
Understanding the difference between benign and malignant adrenal tumors has alway been difficult; this new assay will assist with this medical challenge.
Tracking the Latest Pathogens: Bill Morice, M.D., Ph.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss...
Infectious Diseases on the Move: Bill Morice, M.D., Ph.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss why...
Mosquito-borne disease - Insights
View our comprehensive menu of individually orderable tests and panels for mosquito-borne diseases and our algorithmic approach to testing.
Browse our full menu of individual tests and panels that aid in the diagnosis of tick-borne diseases.
T-cell Lymphoma [Test in Focus] - Insights
Andrew Feldman, M.D., discusses the different tools and techniques Mayo Clinic Laboratories uses to accurately diagnose and classify T-cell lymphomas to help provide clinicians with the diagnostic answers they need to treat their patients.
Complement Testing in the Diagnosis and Management of Thrombotic Microangiopathy - Insights
PACE / State of FLThis month’s “Virtual Lecture” discusses the clinical diagnosis and management, summarizes the testing modalities that guide diagnosis and management, and recognizes the utility of genetic testing as it relates to...
Anti-Platelet Factor 4 Antibody-Mediated Prothrombotic Syndromes - Insights
PACE / State of FLIn this month's "Virtual Lecture," Anand Padmanabhan provides a general overview and science in the field related to heparin-induced thrombocytopenia (HIT), vaccine-induced thrombotic thrombocytopenia (VITT), and...
Heparin Induced Thrombocytopenia (HIT) and the Role of Serotonin Release Assay (SRA) - Insights
In this month's "Hot Topic," Rajiv Pruthi, M.B.B.S., discusses heparin induced thrombocytopenia (HIT), approach diagnosis, and the role of the functional serotonin release assay (SRA).
Nonradioactive assay helps diagnose heparin reaction - Insights
Rajiv Pruthi, M.B.B.S., explains how Mayo Clinic Laboratories’ serotonin release assay achieves high sensitivity and specificity while avoiding the use of radioactive materials. Serotonin release testing is an important tool in the...
Familial Variant Targeted Testing (FMTT) - Insights
In this month's "Hot Topic," Megan Hoenig, M.S., M.P.H., CGC, a licensed and certified genetic counselor with the Division of Laboratory Genetics and Genomics at Mayo Clinic Laboratories, describes the principles and benefits of Familial...
Diagnostic Exploratory Testing - Insights
In this month's "Hot Topic," Nicole Boczek, Ph.D., assistant professor and laboratory director in the Department of Laboratory Medicine and Pathology, and Sarah Barnett, M.S., CGC, discuss diagnostic exploratory testing, explain why it’s...
Clinical and forensic toxicology - Insights
Clinical, forensic, and emergency toxicology testing at Mayo Clinic Laboratories, which aligns with evidence-based clinical laboratory guidelines, uses advanced and emerging technologies and is performed on urine, serum, and meconium...
Therapeutic drug monitoring - Insights
Our comprehensive TDM test menu covers more than 70 drugs across psychiatry, neurology, transplant medicine, oncology, and other clinical disciplines, ensuring accurate, personalized care through advanced analysis and innovation.
CMS Date of Service Policy - Insights
If your organization refers outpatient testing to Mayo Clinic Laboratories (MCL) for molecular pathology tests, the performing laboratory will be required to bill Medicare directly for tests that meet specific requirements. This new...
Pathways Case Studies: April 2024 - Insights
Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff
Pathways Case Studies: June 2024 - Insights
Short, interactive case studies from Mayo Clinic physicians, scientists, and allied health staff
Pathology consultation - Insights
Learn more about how Mayo Clinic Laboratories consultative pathology practice, which is supported by more than 100 board-certified pathologists, can provide expertise on any case.
Pathologists' Important Roles in Community Medicine - Insights
In this episode of Mayo Clinic Laboratories’ “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, speaks with Vipul Trivedi, M.D., chair of Pathology at Mayo Clinic Health System and chair...
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Test Catalog AlgorithmsDownload Test Catalog & Interpretive HandbookNew TestsNY State Informed Consent TestsPerforming LocationsReferred TestsSpecialty TestingTest Updates...
Home - Mayo Clinic Laboratories
Test Catalog AlgorithmsDownload Test Catalog & Interpretive HandbookNew TestsNY State Informed Consent TestsPerforming LocationsReferred TestsSpecialty TestingTest Updates...
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, share insights from...
Hematology Testing - Mayo Clinic Laboratories
Our comprehensive test menu has beencreated to aid in the diagnosis and treatmentselection across the full spectrum of hematologicdisorders.
Fergus Couch, Ph.D., co-authors new guidelines for interpreting ATM cancer gene variants - Insights
Fergus Couch, Ph.D., chair of Mayo Clinic’s Division of Experimental Pathology and Laboratory Medicine, led a team that recently published new National Institutes of Health and U.S. Food and Drug Administration-approved guidelines for the...
The importance of blood inventory and diversity in supply - Insights
Maintaining a diverse and sufficient blood supply is essential for hospital care, as transfusions support many critical treatments. Several known red blood cell antigens make donor-recipient matching complex, especially across diverse...
Top 3 reasons to join us at Leveraging the Laboratory 2025 - Insights
Our annual Outreach Conference, Leveraging the Laboratory, will take place on Sept. 16–17, 2025, in Nashville. This year’s theme, “Vision to Action,” offers a wide variety of perspectives pertaining to health system laboratory outreach...
Independence Day Specimen Shipping Guidelines and Schedule - Insights
Mayo Clinic Laboratories' specimen pickup and delivery schedules will be altered due to the upcoming July 4th holiday. To ensure specimen stability and prevent delays, follow the guidelines outlined below for domestic clients and...