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Liquid biopsy offers noninvasive DNA testing for cancer care - Insights

Gang Zheng, M.D., Ph.D., and Aaron Mansfield, M.D., describe Mayo Clinic Laboratories’ liquid biopsy, which analyzes blood samples for genetic information to guide cancer treatment. The circulating tumor DNA assay uses next generation...

Kelch-11 Autoantibody Test [Test in Focus] - Insights

Divyanshu (Div) Dubey, M.B.B.S., explains how Mayo Clinic Labs’ new Kelch-11 antibody test — the first in the world — can confirm diagnosis, guide treatment, and improve outcomes in patients affected by testicular cancer-associated...

Hot Topic Archives - Page 4 of 5 - Insights

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Neuroimmunology: Updates and antibody test utilization - Insights

In this month’s “Hot Topic,” Andrew McKeon, M.B., B.Ch., M.D., reviews the use of neurological phenotype-based evaluations, the move away from the paraneoplastic evaluation, and upcoming changes to test profiles.

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) - Insights

In this month's "Hot Topic," Eoin Flanagan, M.B., B.Ch., reviews the recent diagnostic criteria for Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD).

Autoimmune Movement Disorders - Insights

The spectrum of autoimmune movement disorders, diagnosis and treatment.

Outreach Quality and Satisfaction - The Patient's View - Insights

As healthcare continues to evolve and payment models become more inclusive of patient satisfaction measures, it is vitally important for laboratories to focus on improving the patient experience. Because the laboratory is a critical element...

MayoACCESS Resources - Mayo Clinic Laboratories

Test Catalog AlgorithmsDownload Test Catalog & Interpretive HandbookNew TestsNY State Informed Consent TestsPerforming LocationsReferred TestsSpecialty TestingTest Updates...

Supporting Patient Care through Comprehensive Molecular and Cytogenetic Neuro-Oncology Testing - Insights

At Mayo Clinic, we offer a comprehensive approach to testing that focuses on the best outcomes for the patient. Our testing method combines molecular and cytogenetic analysis (in addition to a standard morphological and histological...

It Remains Unknown: Link between Gadolinium Exposure via MRI Exams and Health Effects in Patients with Normal Renal Function - Insights

There have been concerns in the U.S. recently about the possible harmful side effects from absorbing gadolinium-based contrast agents into the body during some MRI exams. To address some of the anxiety and concerns over this issue, Paul...

Own your lab - Insights

It delivers insights that put patients on the right pathway. It drives revenue that can bolster the financial stability of the hospital. It elevates the standards of care in the communities it serves – but only if you recognize your lab’s...

Hereditary movement disorders - Insights

Learn about our advanced genetic testing for hereditary movement disorders, including ataxias, Huntington’s disease, and Parkinson’s disease.

Test in Focus - Insights

Our experts discuss the latest from Mayo Clinic Laboratories, so you can stay up to date on the most advanced diagnostics and newly developed tests. Note: Podcasts will not play back on Internet Explorer. Please use an alternative web...

Urinary ammonium testing - Insights

John Lieske, M.D., discusses Mayo Clinic Laboratories' urinary ammonium testing. A test that takes the guesswork out of determining acid base disorders by giving nephrologists a true understanding of a patient’s true urinary ammonium level.

Novel biomarkers added to movement disorders profile - Insights

Andrew McKeon, M.B., B.Ch., M.D., explains how Mayo Clinic Laboratories' expanded movement disorders panel better identifies autoimmune conditions to guide appropriate treatment.

Shining light on one family's struggle: Barbara, Deborah, Pamela, and Rylie - Insights

Before testing at Mayo Clinic Laboratories, Barbara Domaille, Deborah Neville, Pamela Neville, and Rylie Ronnenberg thought there could be a genetic connection to the hip problems they shared. After the testing, they knew for sure.

High-resolution targeted stimulant and phencyclidine (PCP) screen - Insights

In this month’s “Hot Topic,” Paul Jannetto, Ph.D., discusses the high-resolution targeted stimulant and PCP screening test from Mayo Clinic Laboratories, which offers sensitivity and specificity for use in the monitoring and management of...

Test Validation Support - Mayo Clinic Laboratories

Test Validation Support Client systems that are configured with a MayoACCESS HL7 interface can work with our support team to perform validation testing of Mayo test configurations within their laboratory information system...

Laboratory testing utilization: Coccidioides immitis/posadasii serologic testing - Insights

In this month's "Hot Topic," Elitza Theel, Ph.D., shares the recommended approach to serologic testing for assessment or infection with coccidioides.

MCL Whole Genome Sequencing Ordering Checklist MC1235301

MCL Genome Sequencing Ordering Checklist Complete print Genome Sequencing Ordering Checklist Reset Form Instructions Select box test requested

Pharmacogenomics - Insights

Including comprehensive panels and medication targeted assays, Mayo Clinic Laboratories pharmacogenomic testing focuses on clinically actionable genes and enables the detection of more alleles than other testing.

Medication-targeted testing - Insights

Learn more about how medication targeted testing at Mayo Clinic Laboratories can assist in treatment optimization for medication with established pharmacogenomic associations.

A Test in Focus Archives - Insights

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Bobbi Pritt, M.D., Advises How to Avoid Bug-Borne Diseases This Summer - Insights

Bobbi Pritt, M.D., Director of the Clinical Parasitology Lab and Co-Director of Vector-Borne Diseases Lab Services in Mayo Clinic’s Department of Lab Medicine and Pathology, recently spoke with the Post-Bulletin about Lyme disease and West...

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) - Insights

Divyanshu (Div) Dubey, M.B.B.S., describes Mayo Clinic Laboratories' new diagnostic test for CIDP, or chronic inflammatory demyelinating polyneuropathy. The new test detects two antibodies — NF155 and CNTN1 — to enhance diagnosis and guide...

Mitochondrial Disease [Test in Focus] - Insights

Linda Hasadsri, M.D., Ph.D., explains how Mayo Clinic Laboratories’ inclusive approach to mitochondrial disease testing expedites diagnosis. Using innovative methodologies like custom reagents and droplet digital PCR enables precision...

Answers From the Lab - Insights

A Mayo Clinic podcast sharing knowledge and advances in testing, laboratory science, and the people who make it all happen behind the scenes. Note: Podcasts will not play back on Internet Explorer. Please use an alternative web browser, or...

GFAP: Novel Test for a Newly Identified Meningoencephalomyelitis - Insights

Mayo Clinic Laboratories is the only laboratory in the world to offer testing for a novel form of autoimmune meningoencephalomyelitis. Known as autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy, the condition was identified...

Chromogenic Factor VIII and IX Assays: Impact on Diagnosis and Management of Hemophilia - Insights

In this month’s “Hot Topic,” Rajiv Pruthi, M.B.B.S., will discuss different types of hemophilia along with their pathologic basis. He will also cover various types of factor assays such as one stage and chromogenic factor assays for...

Test Validation Support - Mayo Clinic Laboratories

Test Catalog AlgorithmsDownload Test Catalog & Interpretive HandbookNew TestsNY State Informed Consent TestsPerforming LocationsReferred TestsSpecialty TestingTest Updates...

Improvements to downtime process, form provide clarity for clients - Insights

The downtime process and form have been improved to provide clear guidance on the steps clients should take during downtime.

Eye on Innovation - Insights

Eye on Innovation features exciting advances taking place at Mayo Clinic Laboratories. This monthly series shines a spotlight on recently developed tests, and highlights how Mayo Clinic translates ideas and discoveries into testing...

Patient spotlight - Insights

Patients are at the heart of all we do at Mayo Clinic Laboratories. Our laboratory testing can clear the fog of an uncertain diagnosis, point to the next steps in care, and pave the way for better treatment. Our work makes a difference in...

Pediatric CNS Disorder Testing - Mayo Clinic Laboratories

We offer a first-of-its-kind profile including only the antibodies that are pertinent to pediatric CNS disorders—all in one evaluation.

July 2023 - Clinical Microbiology - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Microbiology.

Insights - Insights

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MayoComplete Next-Generation Sequencing: Oncology Subpanels - Insights

In this month's "Hot Topic," Kevin Halling, M.D., Ph.D., discusses new next generation sequencing testing for various tumor types and the rationale for the enhancements that were made; reviews gene additions that are now available in each...

Mayo Clinic Laboratory and Pathology Research Roundup: July 9 - Insights

This week’s Research Roundup highlights the association between inherited germline mutations in cancer predisposition genes and risk of pancreatic cancer.

Research - Insights

The exchange of medical knowledge is a founding principle of Mayo Clinic. William J. Mayo, M.D., said it best: “It is a great thing to make scientific discoveries of rare value, but it is even greater to be willing to share these...

Nailing the Suspect: The Prevalence of Autoimmune Encephalitis Compared with Infectious Encephalitis - Insights

For people with encephalitis, rapid treatment of their acute brain inflammation is critical for avoiding devastating physical and cognitive deficits. But appropriate treatment requires identifying the culprit causing the symptoms.

FDA-approved test expands options for Alzheimer's disease - Insights

Joshua Bornhorst, Ph.D., describes the new, FDA-approved Alzheimer's disease (AD) test and how it differs from Mayo Clinic Laboratories' existing AD evaluation. The laboratory will offer both tests, to ensure flexibility and options for...

Sponsored testing - Insights

Learn about our sponsored testing program and how it can benefit both patients and healthcare providers.

Standard Operating Procedures (SOPs): The 5 W's and How - Insights

PACE/State of FL - The who, what, why, where, when and how of well written effective procedures that can: help to improve the quality of work within the organization, help reduce the number of errors and omissions, and help new people...

Familial Variant Targeted Testing (FMTT) - Insights

In this month's "Hot Topic," Megan Hoenig, M.S., M.P.H., CGC, a licensed and certified genetic counselor with the Division of Laboratory Genetics and Genomics at Mayo Clinic Laboratories, describes the principles and benefits of Familial...

Infectious Diseases - Insights

Learn how our clinical microbiology laboratory can aid in diagnosing pediatric illnesses caused by insects, fungal species, and parasites.

Transforming clinical practice and changing outcomes for brain tumor patients - Insights

The genetic variability of glioma, and its more advanced relative glioblastoma, has made genetic testing to identify biomarkers associated with prognosis and treatment effectivity an integral component of care plan development. However, the...

COVID-19: The pandemic that's forever changed laboratory testing - Insights

Since March 2020, the COVID-19 pandemic has had a lasting impact on the lives of millions of people around the world, including the many brave health care workers who risked their own health to provide lifesaving care to those infected by...

Mayo Clinic Labs @Work: Ona Saras - Insights

As a clinical specialty representative, Ona Saras’ decade-long dedication to patient care and advocacy for cutting-edge testing at Mayo Clinic Laboratories has transformed lives across Northern California and Reno, Nevada. Through personal...

Autoimmune Epilepsy Testing - Mayo Clinic Laboratories

Our phenotype specific testing for autoimmune epilepsy contains only clinically relevant antibodies providing accurate answers for treatment guidance.

Genetic testing - Insights

Featuring a full menu of advanced sequencing assays, Mayo Clinic Laboratories’ genetic test offerings for early-onset gastrointestinal disorders can provide diagnostic clarity that enables customized care.