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State-of-the-art genetics panel optimizes kidney disease treatment - Insights

Linnea M. Baudhuin, Ph.D., and Emily K. Thoreson, M.S., CGC, explain how Mayo Clinic Laboratories renal genetics testing provides comprehensive, accurate and actionable results. Identifying a genetic cause helps guide the complex decisions...

Test helps identify elusive central nervous system pathogens: Robin Patel, M.D. - Insights

Robin Patel, M.D., explains how a new Mayo Clinic Laboratories' assay can identify central nervous system pathogens that standard tests fail to detect. Rapid, precise diagnosis is essential to preventing long-term effects from these...

Mayo Clinic Labs @Work: Shannon Bennett - Insights

As director of Regulatory Affairs for the Department of Laboratory Medicine and Pathology, Shannon Bennett helps safeguard Mayo Clinic’s reputation for quality care by ensuring that its clinical laboratories operate at the highest level of...

Mayo Clinic Labs @Work: Lisa Wortman Raring - Insights

In her role as a proposal writer, Lisa Wortman Raring helps show clients everything Mayo Clinic Laboratories has to offer, making it clear how the organization can best meet their needs and the needs of their patients.

Seeking, and finding, answers, comfort, and hope: Joe Mondloch - Insights

Joe Mondloch and his wife Sue have existed in a grey area of uncertainty due to the unpredictable autoimmune neurological illness Joe has lived with for the last seven years. Rare, incurable, and debilitating, the newly classified disorder...

What's New in Health Care Reform: Dec. 26 - Insights

Top highlights include: FDA panel backs prescribing opioid overdose reversal drug along with painkillers, Surgeon General warns youth vaping is now an "epidemic," international patients seeking cures in the states, Mayo Clinic President and...

Dangerous Goods Training - Insights

Self-paced online training and certification for safe collection, handling, packaging, and shipment of specimens.

MASTERMIND: A Smarter Search for Microbial Diagnostics - Insights

In the war against microbes, human beings are vastly outnumbered—and losing the weapons race.

Michael Camilleri, M.D., and Leslie Donato, Ph.D., Discuss Testing for Bile Acid Malabsorption in Clinical Practice - Insights

In a recent issue of Mayo Clinic's Digestive Diseases, Michael Camilleri, M.D., a gastroenterologist at Mayo Clinic, and Leslie Donato, Ph.D., Co-Director for Cardiovascular Laboratory Medicine, Hospital Clinical Laboratory, and Point of...

Research Suggests Genetics Are Key in Treating Night Sweats - Insights

Hormone therapy is often used to prevent night sweats. But finding the right dose of estrogen can be tricky, with some women needing more estrogen than others to get relief. A new Mayo Clinic study published in Menopause: The Journal of the...

Mayo Clinic Laboratory and pathology research roundup: September 26 - Insights

This week's research roundup feature: Semaglutide in HFpEF across obesity class and by body weight reduction.

Hereditary Oncology Testing [Test in Focus] - Insights

Wei Shen, Ph.D., explains Mayo Clinic Laboratories' new expert-backed, hereditary oncology panels, which use next-generation sequencing to identify genetic mutations linked to increased cancer risk. By only including clinically significant...

Cholesterol biosynthesis and transport - Insights

Check out Mayo Clinic Laboratories’ testing approach to diagnose disorders related to cholesterol biosynthesis and transport.

Peroxisomal biogenesis and metabolism - Insights

Learn more about how Mayo Clinic Laboratories’ testing for peroxisomal biogenesis and metabolism disorders can assist in the identification of these sometimes fatal conditions.

Comprehensive Genetic Test Guides Prescribing of a Transplant Anti-Rejection Drug: Jessica Wright, Pharm.D., BCACP - Insights

Jessica Wright, Pharm.D., BCACP, explains how Mayo Clinic Laboratories' 3A5Q test helps determine initial tacrolimus doses for individuals after non-liver organ transplants. Optimal tacrolimus levels are one of the important factors in...

Coccidioides - Insights

Mayo Clinic Laboratories upfront, screening enzyme-linked immunosorbent assay detects Coccidioides antibodies prior to testing by complement fixation (CF) or immunodiffusion (ID). Samples that result as reactive by are subsequently reflexed...

Biopharma solutions - Insights

Inspired by Mayo Clinic’s tradition of collaboration to break down barriers, expand knowledge, and change medicine, BioPharma Diagnostics brings unmatched expertise and quality to each project. Whether supporting clinical trials, advancing...

Hereditary neuromuscular disorders - Insights

Find out how our distinctive approach to evaluating for inherited neuromuscular disorders uses phenotypic information to streamline diagnosis.

Primary ciliary dyskinesia - Insights

Learn more about Mayo Clinic Laboratories’ robust approach to testing for primary ciliary dyskinesia, a rare genetic condition that can lead to chronic otosinopulmonary disease and infertility in men.

Amino acid disorders - Insights

Learn more about how amino acid metabolism testing at Mayo Clinic Laboratories can assist in diagnosing the most preventable and treatable amino acid disorders.

Allergens - Insights

Browse our menu of immunoglobulin E (IgE) antibody testing, which can be useful in the evaluation of patients suspected of having an allergic disease.

Colorectal Cancer NGS Testing - Mayo Clinic Laboratories

Our panel was designed to meet current guidelines and remain targeted enough to provide clinically actionable results.

Week in Review: April 8 - Insights

Today's Highlights Include: 5 reasons to consider becoming an organ donor, why so many women in middle age are on antidepressants, and should you get a second COVID-19 vaccine booster?

Mayo Clinic Laboratory and Pathology Research Roundup: December 26 - Insights

This week's research roundup feature: Histoplasma and Blastomyces antigen detection assays are commonly used diagnostic tools. However, a high level of cross-reactivity between these antigens prevents definitive pathogen identification by...

Assay enhances and simplifies M-proteins screening: David Murray, M.D., Ph.D. - Insights

David Murray, M.D., Ph.D., explains how Mayo Clinic Laboratories' MASSFIX Quantitation assay provides next-generation screening for M-proteins, which are associated with multiple myeloma and other diseases. The assay better quantitates the...

Thrombotic Microangiopathies (TMA) [Test in Focus] - Insights

Meera Sridharan, M.D., Ph.D., explains Mayo Clinic Labs’ testing approach for atypical hemolytic uremic syndrome (aHUS). The serological complement panel examines nine analytes to gain a thorough understanding of the complement cascade to...

Mayo Clinic Laboratory and Pathology Research Roundup: March 12 - Insights

This week's research roundup feature: C3 glomerulopathy (C3G) is a rare disease resulting from dysregulation of the alternative pathway of complement. C3G includes C3 glomerulonephritis (C3GN) and dense deposit disease (DDD), both of which...

Updates Streamline Autoimmune Neurology Testing: Anastasia Zekeridou, M.D., Ph.D. - Insights

Anastasia Zekeridou, M.D., Ph.D., explains how Mayo Clinic Laboratories' updated panels and methodology boost the accuracy and efficiency of testing for three autoimmune neurology biomarkers. Early diagnosis is key to managing debilitating...

Assay identifies biomarker of autoimmune encephalitis subtype: Andrew McKeon, M.B., B.Ch., M.D. - Insights

Antibody against the GABA-A receptor is a biomarker of autoimmune encephalopathy that occurs across the lifespan, and disproportionately affects children. In this test-specific episode of the "Answers From the Lab" podcast, Andrew McKeon,...

Neurofascin 155 IgG4 Antibody Test [Test in Focus] - Insights

John Mills, Ph.D., explains Mayo Clinic Laboratories' new neurofascin 155 (NF155) IgG4 antibody test, which is the first commercially available test in the U.S. to use flow cytometry to detect for NF155 antibodies and confirm diagnosis of...

Five steps for successful outreach program implementation - Insights

Learn the five elements essential to successfully implementing a complex outreach program project and what is at risk if you miss an element.

Education - Insights

Learn more about educational offerings available to primary clients of Mayo Clinic Laboratories.

New Panels Help Find Cause of Rapidly Progressive Dementia: Gregg Day, M.D. - Insights

Rapidly progressive dementia (RPD) is an umbrella term covering many devasting conditions, including Creutzfeldt-Jakob disease (CJD). Gregory (Gregg) Day, M.D., explains how Mayo Clinic Laboratories' unique RPD evaluation and new CJD test...

Mayo Clinic Laboratories and Progentec launch lupus advanced biomarker testing services - Insights

As a successful outcome of the collaboration announced in 2023, Progentec’s proprietary biomarker blood tests for the proactive management of systemic lupus erythematosus are now available through Mayo Clinic Laboratories.

Tests Aid Diagnosis of Cancer-Associated Neurological Disorders: Divyanshu Dubey, M.B.B.S. - Insights

Divyanshu Dubey, M.B.B.S., explains how Mayo Clinic Laboratories' unique PDE10A and TRIM46 tests facilitate the management of central nervous system disorders triggered by cancers. Early diagnosis and treatment are important for managing...

Panel Detects Demyelinating Neuropathy Biomarkers: John Mills, Ph.D., and Divyanshu Dubey, M.B.B.S. - Insights

John Mills, Ph.D., and Divyanshu Dubey, M.B.B.S., explain how Mayo Clinic Laboratories' new test panel can distinguish among various potential causes of demyelinating neuropathies. Test results are important for managing these devastating...

Gynecological NGS panels offer cost-effective cancer testing: Sounak Gupta, M.B.B.S., Ph.D. - Insights

Sounak Gupta, M.B.B.S., Ph.D., explains how Mayo Clinic Laboratories' gynecological NGS panels provide focused assessments of gynecological cancers. The cost-effective tests fill the gap between single gene assays and large cancer panels,...

Urologic panels provide focused cancer testing: Sounak Gupta, M.B.B.S., Ph.D. - Insights

Sounak Gupta, M.B.B.S., Ph.D., explains how Mayo Clinic Laboratories' urologic panels efficiently inform prognosis and individualized cancer treatment. The carefully curated panels fill the void between single gene assays and large NGS...

Assay identifies most known membranous nephropathy antigens: Sanjeev Sethi, M.D., Ph.D. - Insights

Sanjeev Sethi, M.D., Ph.D., explains how Mayo Clinic Laboratories' new mass spectrometry test (Mayo ID: MSMN) identifies most antigens now known to cause membranous nephropathy. Precise identification of antigens is important for optimal...

Panel Boosts Therapeutic Monitoring of IBD Drug: Maria Alice Willrich, Ph.D., and Melissa Snyder, Ph.D. - Insights

Maria Alice Willrich, Ph.D., and Melissa Snyder, Ph.D., explain how Mayo Clinic Laboratories' unique risankizumab panel measures levels of both that drug and its antibodies in patients' blood. The results can better guide the management of...

Targeted panel boosts accuracy of hereditary pancreatitis testing: Linda Hasadsri, M.D., Ph.D., and Huong T. Cabral, M.S., C.G.C. - Insights

Linda Hasadsri, M.D., Ph.D., and Huong T. Cabral, M.S., C.G.C., explain how Mayo Clinic Laboratories' targeted test panel facilitates accurate diagnosis of hereditary pancreatitis, which heightens the risk for pancreatic cancer. Test...

Enhanced Solid Tumor NGS Panel Broadens Genetic-Variants Detection: Robert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S. - Insights

Robert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S., explain how Mayo Clinic Laboratories' enhanced MayoComplete Solid Tumor Panel better profiles tumor genetics. Defining tumor pathogenesis can guide targeted...

Assay provides quick diagnosis of VEXAS syndrome: David S. Viswanatha, M.D. - Insights

David S. Viswanatha, M.D., explains how Mayo Clinic Laboratories' new assay provides rapid, definitive diagnosis of VEXAS, a recently identified syndrome affecting older men. Early diagnosis is key to managing the syndrome, which severely...

Test identifies Lynch syndrome for targeted cancer monitoring: Wei Shen, Ph.D., and Rhianna Urban, M.S., CGC - Insights

Wei Shen, Ph.D., and Rhianna Urban, M.S., CGC, explain how Mayo Clinic Laboratories' gene panel establishes a diagnosis of Lynch syndrome, which heightens the risk for several cancers. Test results can guide targeted cancer surveillance for...

Unique Test Screens for Recently Identified Peripheral Neuropathy: Matthew Schultz, Ph.D., and Amy White, M.S., CGC - Insights

Matthew J. Schultz, Ph.D., and Amy L. White, M.S., CGC, explain how Mayo Clinic Laboratories' unique urine assay (Mayo ID: SORD) screens for peripheral neuropathy arising from SORD gene variants. Although recently identified, SORD-related...

Disaccharidase Activity Panel [Test in Focus] - Insights

Pua Hopson, D.O., discusses Mayo Clinic Labs’ new disaccharidase activity panel, which measures levels of five digestive enzymes to identify deficiencies that cause carbohydrate maldigestion and can lead to chronic conditions like celiac...

Noninvasive plasma biomarker testing provides faster answers: Alicia Algeciras-Schimnich, Ph.D. - Insights

Alicia Algeciras-Schimnich, Ph.D., discusses Mayo Clinic Laboratories’ new noninvasive plasma biomarker assay for Alzheimer’s disease, an accessible, highly accurate testing option for individuals age 50 and above who are experiencing mild...

Unique testing helps identify cause of sudden cardiac death: Linnea Baudhuin, Ph.D., and Kate Kotzer, M.S., CGC - Insights

Linnea Baudhuin, Ph.D., and Kate Kotzer, M.S., CGC, describe how Mayo Clinic Laboratories' postmortem genetic tests can provide answers after a sudden unexplained cardiac death. Test results are important for managing family members' risk...

Genetic Tests Identify Risk of Fluoropyrimidine-Induced Toxicity: Ann Moyer, M.D., Ph.D. - Insights

Ann Moyer, M.D., Ph.D., explains how Mayo Clinic Laboratories' unique genetic tests identify patients at high risk of severe reactions to fluoropyrimidines — a type of chemotherapy drug. Test results can guide clinical decision-making for...

Assay Aids Diagnosis of Resistant Hypertension: John Lieske, M.D., and Sandra Taler, M.D. - Insights

John Lieske, M.D., and Sandra Taler, M.D., explain how Mayo Clinic Laboratories' mass spectrometry assay helps evaluate patients for resistant hypertension. The test can detect antihypertensive medications in urine, providing evidence of...