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Immunobullous Diseases: Paraneoplastic Pemphigus (PNP) - Insights

underlying malignancy, called paraneoplastic pemphigus. She will also discuss the specialized tissue and serum testing that is required to establish the diagnosis....

newborn_screen_follow-up_for_pompe_disease.pdf

Medical Education and Research (MFMER). All rights reserved. 09/2024 Newborn Screen Follow-up for Pompe Disease Newborn screen result: decreased acid alpha-glucosidase (GAA) Assess clinically (including...

Preeclampsia - Insights

Our serum test is the first preeclampsia-specific test that can be used to stratify patients into low- or high-risk categories, indicating whether a patient is at risk for developing preeclampsia with...

Congenital disorders of glycosylation - Insights

glycosylation and its importance in human biology, highlight laboratory testing, and offer strategies to screen and diagnose CDGs....

Thankful for Tygh: The Derossett Family - Insights

A Mayo Clinic Laboratories newborn screening panel detects a rare disease and paves the way for life-sustaining treatment....

Alcohol - Mayo Clinic Laboratories

08g%) therefore blood is the prefer sample type for the legal determination of ethanol. However, serum/plasma, are suitable specimens for the determination of ethanol for clinical indicat......

Infectious diseases - Insights

rapid identification and in-depth characterization of the bacterial, viral, fungal, and parasitic agents of infectious diseases....

A novel testing approach for newly identified VEXAS syndrome - Insights

simultaneously worked on a single gene assay to allow doctors to test specifically for UBA1 mutations to screen patients for VEXAS syndrome. The team opted for a droplet digital PCR test — a novel and highly accurate...

celiac_disease_serology_cascade_test_algorithm.pdf

for Medical Education and Research (MFMER). All rights reserved. Interpretive report includes: ■ Serum IgA ■ Tissue transglutaminase antibody, IgA ■ Endomysial antibody, IgA ■ Gliadin (deamidated) antibody...

Light Protection List - Mayo Clinic Laboratories

from light to ensure specimen integrity. Mayo Clinic Laboratories provides amber-colored tubes for serum and plasma (Supply T915) and urine (Supply T59......

antinuclear-antibody-interpretive-algorithm.pdf

Antinuclear Antibody Interpretive Algorithm NAIFA / Antinuclear Antibodies Hep-2 Substrate, IgG, Serum Consider testin......

autoimmune-paraneoplastic-myelopathy-evaluation-algorithm-serum.pdf

Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Myelopathy Evaluation Algorithm-Serum ■ TRIM46 antibody by CBA ■ TRIM46 antibody by IF titer assay ■ Amphiphysin antibody by immunoblo...

Mayo Clinic Laboratory and pathology research roundup: March 22 - Insights

This Feature Includes: A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis....

Tests aid diagnosis of primary biliary cholangitis: Anne Tebo, Ph.D. - Insights

Anne Tebo, Ph.D., explains how Mayo Clinic Laboratories' new serum tests help overcome the challenges of diagnosing primary biliary cholangitis, or PBC. Test results can guide clinical care for patients...

celiac_disease_diagnostic_testing_algorithm.pdf

Disease Diagnostic Testing Algorithm Testing for selective IgA deficiency IGA / Immunoglobulin A (IgA), Serum TTGA / Tissue Transglutaminase Antibody, IgA, Se......

Phlebotomy Top Gun: Order of Draw-Do We Still Care? - Insights

recommendations for routine blood collection. Specifically, does evidence demonstrate a need to collect serum tubes before either potassium EDTA or citrate tubes?...

autoimmune-paraneoplastic-encephalopathy-evaluation-algorithm-serum.pdf

(MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Encephalopathy Evaluation Algorithm-Serum ■ ANNA-1 antibody by immunoblot ■ ANNA-2 antibody by immunoblot ■ ANNA-1 antibody by IF ti....

autoimmune-paraneoplastic-dementia-evaluation-algorithm-serum.pdf

Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Dementia Evaluation Algorithm-Serum Glutamic acid decarboxylase (GAD65) antibody assay ■ Antineuronal nuclear antibody-type 1 (ANNA-1)...

autoimmune-paraneoplastic-epilepsy-evaluation-algorithm-serum.pdf

Research (MFMER). All rights reserved. 05/2024 Autoimmune/Paraneoplastic Epilepsy Evaluation Algorithm-Serum ■ ANNA-1 antibody by immunoblot ■ ANNA-2 antibody by immunoblot ■ ANNA-2 antibody by IF titer...

autoimmune-paraneoplastic-movement-disorder-evaluation-algorithm-serum.pdf

All rights reserved. 05/2024 Autoimmune/Paraneoplastic Movement Disorder Evaluation Algorithm – Serum ■ GFAP alpha subunit antibody by CBA ■ GFAP alpha subunit antibody by IF titer assay ......

Interpretation of qualitative and quantitative urine opiate tests for pain management patients - Insights

In this month’s “Hot Topic,” Paul Jannetto, Ph.D., discusses the use of qualitative urine screening assays and quantitative confirmatory testing to determine compliance in pain management patients....

https://www.mayocliniclabs.com/-/media/it-mmfiles/Special%20Instructions/3/5/6/Acute%20Tick%20Borne%20Disease%20Testing%20Algorithm%20int

Disease Testing Algorithm for Mayo Clinic Order: SFGP / Spotted Fever Group Antibody, IgG and IgM, Serum Empiric treatment encouraged for high risk......

acute_tick-borne_disease_testing_algorithm.pdf

Acute Tickborne Disease Testing Algorithm Order: SFGP / Spotted Fever Group Antibody, IgG and IgM, Serum Empiric treatment encouraged for high risk patients while......

Oral fluid offers an alternative specimen for controlled substance monitoring: Paul Jannetto, Ph.D. - Insights

Paul Jannetto, Ph.D., explains the advantages that Mayo Clinic Laboratories' oral fluid drug screening offers over typical urine tests. Oral samples are easier to collect and harder to adulterate....

pediatric-autoimmune-encephalopathy-central-nervous-system-disorders-evaluation-algorithm-serum.pdf

05/2024 Pediatric Autoimmune Encephalopathy/ Central Nervous System Disorders Evaluation Algorithm-Serum ■ ANNA-1 immunoblot ■ ANNA-2 immunoblot ■ ANNA-1 IF titer assay ■ mG......

connective_tissue_disease_cascade.pdf

reserved. Connective Tissue Disease Cascade ≥20 U <20 U CTDC / Connective Tissue Diseases Cascade, Serum Cyclic citrullinated peptide antibodies, IgG Positive result support......

Precision pain management - Insights

Our liquid chromatography-tandem mass spectrometry, high-resolution accurate mass (LC-MS/MS HRAM) screens, and confirmatory testing for controlled substances are available based on the needs of your patients...

Precision pain management - Insights

Our liquid chromatography-tandem mass spectrometry, high-resolution accurate mass (LC-MS/MS HRAM) screens, and confirmatory testing for controlled substances are available based on the needs of your patients...

Cases with Dr. Keeney: Case #3 - Insights

case presents an unusual colon polyp on an asymptomatic early 70 year-old male. At the time of screening colonoscopy, two small left colon polyps were noted and excised. What is the diagnosis?...

vitamin_b12_deficiency_evaluation.pdf

ng/L>400 ng/L 150-400 ng/L ≤0.4 nmol/mL >0.4 nmol/mL INDETERMINATE ACASM / Pernicious Anemia Cascade, Serum Testing begins wit......

Extended Spectrum Beta Lactamase Testing - Insights

lactamase (ESBL) testing. Used to screen for the presence of multi-drug resistant gram-negative bacteria in donor stool intended for fecal microbiota transplantation, the screening test is performed on stool...

Mayo Clinic Laboratory and Pathology Research Roundup: March 11 - Insights

This week’s Research Roundup highlights an assay to rapidly screen for immunoglobulin light chain glycosylation: a potential path to earlier AL diagnosis for a subset of patients and several other research...

CPT codes and LOINC update: April 2021 - Insights

The following list includes updates posted to mayocliniclabs.com during the month of April.

Week in Review: February 17 - Insights

adults, Governments target medical debt with COVID relief funds and Minnesota being the 1st state to screen all newborns for serious viral infection....

Breast cancer panel halves turnaround time: Wei Shen, Ph.D. - Insights

new breast cancer panel provides rapid results to guide critical decisions about treatment and screening....

postmortem_screening_algorithm.pdf

factors present Contact Biochemical Genetics Laboratory 800-533-1710 ■ Order PMSBB / Postmortem Screening, Bile and Blood Spots ■ Collect appropriate specime......

newborn_screen_follow-up_for_severe_combined_immunodeficiency_syndrome__scid_.pdf

Research (MFMER). All rights reserved. 02/2024 Decreased T-cell receptor excision circles on newborn screening test Perform: ■ CBC with differential ■ TBBS / Quantitative Lymphocyte Subsets: T, B, and Natural...

newborn_screen_follow-up_for_mucopolysaccharidosis_type_ii.pdf

Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 02/2024 Newborn screening results: ■ Decreased iduronate-2-sulfatase activity ■ Elevated dermatan and heparan sulfate Order...

lysosomal_storage_disorders_screen_interpretive_algorithm.pdf

Medical Education and Research (MFMER). All rights reserved. 04/2022 Lysosomal Storage Disorders Screen Interpretive Algorithm One of the following: ■ α-Mannosidosis ■ Aspartyglucosaminuria ■ β-Mannosidosis...

Direct Ethanol Biomarker Testing: PETH - Insights

with a window of detection of about two to four weeks — compared with five days for urine-based screening for alcohol use....

Chromium and Cobalt - Insights

A Mayo Clinic study found that synovial fluid testing for those elements is more sensitive than serum or whole blood testing....

newborn_screen_follow-up_for_guanidinoacetate_methyltransferase_deficiency__gamt_.pdf

Foundation for Medical Education and Research (MFMER). All rights reserved. Reviewed 05/2025 Newborn screen result: Elevated guanidinoacetate Order: ■ CRDPU / Creatine Disorders Panel, Urine ■ CRDPP / Creatine...

Multigene panel provides efficient ataxia diagnosis: Angela Pickart, M.S., CGC, and Emily Lauer, M.S., CGC - Insights

ataxia. Precise diagnosis of this complex movement disorder helps guide patient treatment and family screening....

newborn_screen_follow-up_for_mucopolysaccharidosis_type_i.pdf

Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. 03/2024 Newborn screen result: decreased alpha-L-iduronidase (IDUA) Order 1 from each of the following groups: ■ IDUAW...

Developing New Tests to Find and Defeat Cancer at Earliest Stages - Insights

Some early-stage cancers are missed by conventional screening and are only detected when symptoms occur. Mayo Clinic is collaborating with Grail, a life science company, and Sutter Health of California...

Autoimmune Myelopathy Evaluation [Test in Focus] - Insights

sensation, neuropathic pain, and bowel and bladder dysfunction). Autoimmune myelopathy evaluation of serum and spinal fluid can assist in the diagnosis and aid distinction from other causes of myelopathy (multiple...

Pancreatic Elastase - Insights

Hopson, D.O., a Mayo Clinic pediatric gastroenterologist, explains the pancreatic elastase test — a screening test that can be useful when symptoms point to the possibility of exocrine pancreatic insufficiency...

What's New in Health Care Reform: Jan. 30 - Insights

funds first artificial pancreas study in the United States for pregnant women, cervical cancer screenings save lives, and the health benefits of olive oil....

CPT codes and LOINC update: October 2021 - Insights

The following list includes updates posted to mayocliniclabs.com during the month of October.

Unveiling a novel hemoglobinopathy classification - Insights

first instance of the disorder was found in 2017 when an obstetric patient underwent a routine screening for blood-related illnesses such as sickle cell disease and thalassemia. Upon completion of additional...