Chain of Custody Testing - Insights
Loralie Langman, Ph.D., explains the difference between chain of custody and clinical toxicology testing. Chain of custody is a process used for toxicology testing when the results might have legal implications for the individual tested....
Neurofascin 155 IgG4 Antibody Test [Test in Focus] - Insights
John Mills, Ph.D., explains Mayo Clinic Laboratories' new neurofascin 155 (NF155) IgG4 antibody test, which is the first commercially available test in the U.S. to use flow cytometry to detect for NF155 antibodies and confirm diagnosis of...
Disaccharidase Activity Panel [Test in Focus] - Insights
Pua Hopson, D.O., discusses Mayo Clinic Labs’ new disaccharidase activity panel, which measures levels of five digestive enzymes to identify deficiencies that cause carbohydrate maldigestion and can lead to chronic conditions like celiac...
MAG Antibody Testing [Test in Focus] - Insights
John Mills, Ph.D., explains Mayo Clinic Laboratories’ approach to MAG antibody testing. The ELISA-based assay uses higher reference ranges and human MAG antigen to detect MAG antibodies, which are associated with a rare, hard-to-treat...
State-of-the-art genetics panel optimizes kidney disease treatment - Insights
Linnea M. Baudhuin, Ph.D., and Emily K. Thoreson, M.S., CGC, explain how Mayo Clinic Laboratories renal genetics testing provides comprehensive, accurate and actionable results. Identifying a genetic cause helps guide the complex decisions...
Learn more about how Mayo Clinic Laboratories’ unique testing for sphingolipidoses, including Gaucher and Krabbe diseases, can confirm diagnosis and guide disease management.
Learn how our pediatric neuro-oncology testing includes both comprehensive MayoComplete next-generation sequencing and chromosomal microarray.
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This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. This case sub-specialty is Renal.
February 2020 - Laboratory Genetics & Genomics - Insights
A 71 yr old female with a history of a central nervous system lymphoma, an allogenic stem cell transplant and graft versus host disease was tested for
hereditary_peripheral_neuropathies_testing_algorithm.pdf
Inherited neuropathy suspected; Insidious onsets progressive (years)* The following tests should be performed in all adult patients: HbA1c or glucose tolerance, vitamin B12, monoclonal proteins. Order PMPDD / PMP22 Gene, Large Deletion...
Liquid biopsy offers noninvasive DNA testing for cancer care - Insights
Gang Zheng, M.D., Ph.D., and Aaron Mansfield, M.D., describe Mayo Clinic Laboratories’ liquid biopsy, which analyzes blood samples for genetic information to guide cancer treatment. The circulating tumor DNA assay uses next generation...
Multiple Sclerosis Profile Updates - Insights
Maria Alice Willrich, Ph.D., explains kappa free light chain testing — Mayo Clinic Laboratories' data-driven approach to diagnose multiple sclerosis. The automated assay is more sensitive, cost-effective, and faster than traditional...
Novel malabsorption panel speeds diagnosis - Insights
Puanani Hopson, D.O., explains how Mayo Clinic Laboratories’ malabsorption panel can provide timelier diagnosis for children with chronic diarrhea or unexplained weight loss. The novel panel, which bundles four existing tests, requires just...
TPNUQ genotyping assay - Insights
Ann Moyer, M.D., Ph.D., discusses TPNUQ, Mayo Clinic Laboratories' genotyping test for identifying patients at risk for thiopurine toxicity. Used prior to therapy initiation, our assay evaluates for nuances in both TPMT and NUDT15, which...
Direct Ethanol Biomarker Testing: PETH - Insights
Paul Jannetto, Ph.D., describes Mayo Clinic Laboratories' new direct biomarker test for alcohol consumption. PETH is a blood test with a window of detection of about two to four weeks — compared with five days for urine-based screening for...
Autoimmune Axonal Evaluation - Insights
Div Dubey, M.B.B.S., explains Mayo Clinic Laboratories' phenotypic testing approach for autoimmune axonal neuropathy. The comprehensive, serologic panel detects for antibodies with clinical relevance to the disease to provide clarity on...
Neurofilament Light Chain (NFLC) - Insights
Alicia Algeciras, Ph.D., describes Mayo Clinic Laboratories’ new blood test to detect NFLC, or neurofilament light chain protein. NFLC is a biomarker for several neurodegenerative conditions. The new assay can determine if a patient’s...
Addiction rehab monitoring assay - Insights
Paul Jannetto, Ph.D., and Loralie Langman, Ph.D., discuss Mayo Clinic Laboratories' unique approach to urine drug testing for addiction rehabilitation. Designed to guide and monitor therapy, the comprehensive profile tests for the most...
Precision therapeutics can individualize depression treatment - Insights
Ann Moyer, M.D., Ph.D., and Paul Jannetto, Ph.D., explain how precision therapeutics can improve treatment for patients with major depressive disorder. The optimal antidepressant medication and dose vary among individuals. Pharmacogenomic...
PCD test provides definitive diagnosis of a rare disease - Insights
Joseph Maleszewski, M.D., and Marie-Christine Aubry, M.D., explain how Mayo Clinic Laboratory can provide definitive diagnosis of primary ciliary dyskinesia (PCD). Mayo Clinic's expertise and technology have earned the laboratory's...
NELL-1 [Test in Focus] - Insights
Sanjeev Sethi, M.D., Ph.D., discusses how Mayo Clinic Laboratories’ new immunohistochemistry test for the detection of NELL-1 antigen, a biomarker for membranous nephropathy found in 10% to 15% of patients, provides diagnostic certainty and...
Colorectal panel provides detailed cancer information - Insights
Rondell Graham, M.B.B.S., describes Mayo Clinic Laboratories' new colorectal cancer panel. The assay covers more genes to better inform decision-making about prognosis, targeted therapies and a hereditary cancer syndrome.
Focused Pharmacogenomics Panel [Test in Focus] - Insights
Ann Moyer, M.D., Ph.D., explains Mayo Clinic Labs’ new focused pharmacogenomics panel, a real-time, PCR-based testing approach that assesses 10 genes known for their drug-gene associations, to provide guidance on medication selection for...
Inflammatory Bowel Disease: IBDP2 - Insights
In this test specific episode of the "Answers From the Lab" podcast, Melissa Snyder, Ph.D., explains how IBDP2, when used after first-line testing has failed, can distinguish between ulcerative colitis and Crohn’s disease.
Extended Spectrum Beta Lactamase Testing - Insights
Audrey Schuetz, M.D., provides a detailed overview of Mayo Clinic Laboratories’ new culture-based extended spectrum beta lactamase (ESBL) testing. Used to screen for the presence of multi-drug resistant gram-negative bacteria in donor stool...
Mayo Clinic Health System Cannon Falls Laboratory Cannon Falls, Minnesota Vipul A. Trivedi, MD CAP Number: 8852996 AU-ID: 1750669 CLIA Number: 24D0398077 The organization named above meets all applicable standards for...
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CPT codes and LOINC update: October 2020 - Insights
The following list includes updates posted to mayocliniclabs.com during the month of October.
Infectious diseases - Insights
Mayo Clinic BioPharma Diagnostics offers access to the clinical trial infectious disease testing capabilities of Mayo Clinic’s internationally renowned clinical microbiology laboratories. With more than 70 years of testing experience, our...
Infectious diseases - Insights
Mayo Clinic offers a broad selection of tests designed for rapid identification and in-depth characterization of the causative agents of infectious diseases.
Serving more than 60 countries, Mayo Clinic Laboratories is creating a new standard for global diagnostic testing, offering international clients a vast test menu, access to Mayo Clinic experts, superior customer service, and more.
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helicobacter_pylori_diagnostic_algorithm.pdf
≥60 years old; OR Alarming signs and symptoms: ■ Family history of proximal gastrointestinal cancer ■ Previous malignancy of the esophagus or stomach ■ Unexplained iron-deficiency anemia ■ Palpable mass or lymphadenopathy ■ Melena ■...
This “phlebotomy webinar” will walk learners through the quality improvement methodology and describe PDSA cycle interventions that were implemented in this unit which successfully reduced the amount of canceled labs due to specimen...
Global capabilities - Insights
Check out how Mayo Clinic Laboratories optimized global capabilities facilitate individualized solutions that ensure international clients receive expeditious, accurate answers.
Improving diagnosis and treatment of Helicobacter pylori - Insights
Mayo Clinic Laboratories now offers a noninvasive approach for the molecular detection of H. pylori, with results that include prediction of clarithromycin resistance delivered within 24 hours.
Mitochondrial Disease [Test in Focus] - Insights
Linda Hasadsri, M.D., Ph.D., explains how Mayo Clinic Laboratories’ inclusive approach to mitochondrial disease testing expedites diagnosis. Using innovative methodologies like custom reagents and droplet digital PCR enables precision...
Myasthenia Gravis [Test in Focus] - Insights
Christopher Klein, M.D., discusses Mayo Clinic’s updated myasthenia gravis and Lambert-Eaton syndrome testing approach. Automatic reflex to second-line testing saves time and increases sensitivity and specificity to confirm diagnosis in...
West Nile virus [Test in Focus] - Insights
Bobbi Pritt, M.D., discusses how Mayo Clinic Labs’ updated PCR assay for West Nile virus provides increased sensitivity to detect virus RNA in multiple sources, identifies two virus lineages, and confirms diagnosis.