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Lupus - Insights

Mayo Clinic Laboratories’ novel lupus testing, offered in partnership with Progentec Diagnostics, can help characterize disease activity and predict disease flares.

Congenital disorders of glycosylation - Insights

In this month’s “Hot Topic,” Gessi Pino, a genetic counselor in the Biochemical Genetics Lab at Mayo Clinic, and Kimiyo Raymond, M.D., a clinical consultant in the laboratory and an expert in Congenital Disorders of Glycosylation (CDG),...

Optic Neuritis in the Era of Biomarkers - Insights

Antibodies to aquaporin-4 and myelin oligodendrocyte glycoprotein (MOG) are recently described biomarkers seen in a subset of atypical optic neuritis which have revolutionized our understanding of the condition. In this “Hot Topic,” my...

Top Gun Phlebotomy - Butterfly Use: The Good, the Bad, and the Ugly - Insights

In this month’s “Hot Topic,” Brad Karon, M.D., Ph.D., will discuss recent information on the advantages and disadvantages of using butterfly needles for blood collection.

New tests launched in November - Insights

In November 2021, Mayo Clinic Laboratories announced thirty four new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

Selecting Pathology Specimens for Solid Tumors Next-Generation Sequencing - Insights

In this month’s “Hot Topic,” Sounak Gupta, M.B.B.S., Ph.D., discusses selecting tissues and other tissue considerations for molecular testing. He also reviews tissue metrics and requirements, which differ based on test platforms. It is...

Autoimmune Encephalitis Misdiagnosis - Insights

In this month's "Hot Topic," Eoin Flanagan, M.B., B. Ch., discusses the important issue of autoimmune encephalitis misdiagnosis and identifies red flags that be useful in clinical practice to suggest alternative diagnoses and highlight...

Behind the scenes in neural antibody testing - Insights

In this month’s “Hot Topic,” John Mills, Ph.D., explains the central role of tissue immunofluorescence in the identification of neural antibodies and discusses the benefits of an integrated laboratory approach to the development and...

Pathways Case Studies: June 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for June include the following sub-specialties: Gastroenterology Pathology,...

Use of Artificial Intelligence and Digital Slide Scanning for Detection of Intestinal Protozoa in Trichrome-Stained Stool Specimens - Insights

In this month's "Hot Topic," Bobbi Pritt, M.D., describes the challenges to traditional microscopy for the detection of protozoa in stool specimens, lists potential uses of artificial intelligence in parasite detection, and discusses...