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Pushing the envelope on personalized medicine - Insights

Recognizing the powerful role genes can play in diagnosing illness and guiding treatment, the Division of Laboratory Genetics and Genomics at Mayo Clinic spearheaded a testing expansion, implementing and upgrading more than 60 advanced...

Comprehensive testing helps diagnose and manage rare genetic disorder: Lauri Sieben - Insights

Multiple doctors and multiple examinations could not figure out why Lauri Sieben had spent much of her life “never feeling quite right” physically. Fortunately for Lauri, that changed after her daughter Christy began working as a genetic...

Defying all odds and exploring a remarkable journey beyond diagnosis: Mike Knudson - Insights

In August of 2021, 28-year-old Mike Knudson, a Twin Cities resident known for his vibrant and active lifestyle, set out on what he anticipated to be an adventurous hiking vacation to the picturesque Glacier National Park in Montana. Little...

Cutting-Edge Bacterial Testing for the Diagnosis of Patient Infections and Outbreak Mitigation - Insights

Mayo Clinic Laboratories is one of the few laboratories in the country to offer two special sequencing-based tests for bacteria in its catalog. The first test is designed to help protect patients by investigating potential outbreaks of a...

Neuroimmunology: Updates and antibody test utilization - Insights

In this month’s “Hot Topic,” Andrew McKeon, M.B., B.Ch., M.D., reviews the use of neurological phenotype-based evaluations, the move away from the paraneoplastic evaluation, and upcoming changes to test profiles.

Weeding Through the Information: Interpreting Laboratory Tests to Determine New vs. Residual Use of Marijuana - Insights

In this month's "Hot Topic," Paul Jannetto, Ph.D., identifies how to determine new vs. residual use of marijuana in a patient, and teaches how to calculate the carboxy-tetrahydrocannabinol (carboxy-THC) to creatinine ratio along with a...

Alzheimer's Disease CSF Biomarkers - Insights

In this month's "Hot Topic," Alicia Algeciras, Ph.D., DABCC, and Joshua Bornhorst, Ph.D., DABCC, discuss Alzheimer's disease CSF biomarkers.

PD-L1 Testing by Immunohistochemistry - Insights

In this month's "Hot Topic," Anja Roden, M.D., discusses the role of PD-L1 interaction in the immune system, challenges of PD-L1 testing, and current PD-L1 companion testing in various tumor types.

QuantiFERON-TB Gold Plus - Insights

In this month’s “Hot Topic,” Elitza Theel, Ph.D. will discuss a new interferon-gamma release assay that can assist in the detection of individuals that are infected with tuberculosis.

MASS-FIX - Insights

Learn more about matrix-assisted laser desorption/ionization-time of flight mass spectrometry and the identification of plasma cell disorders.