Diagnostic Testing Algorithms for Celiac Disease - Insights
In this month's "Hot Topic," Melissa Snyder, Ph.D., co-director of the antibody immunology laboratory at Mayo Clinic, discusses celiac disease and the role of diagnostic testing algorithms.
IMPACTS Team Continues to Combat Life-Threatening Arthropod-Borne Infections in Belize - Insights
Now in its second year of a five-year initiative to better understand and detect arboviruses in Belize, the IMPACTS (Integrated Mayo Clinic Program for Arbovirus Community health education Training and Surveillance) project has expanded its...
Raising the Bar on Newborn Screening Test Performance - Insights
Newborn screening panels that test for a variety of conditions are available in every state; however, test performance and response rate by each state are very different. Mayo Clinic's Biochemical Genetics Laboratory created the...
Gadolinium-based contrast agents (GBCAs) have revolutionized MRIs by increasing the clinical utility and detection sensitivity of these exams. GBCAs also contain gadolinium, a rare earth metal with unique chemical properties. This article...
In this month's "Hot Topic," Paul Jannetto, Ph.D., identifies how to determine new vs. residual use of marijuana in a patient, and teaches how to calculate the carboxy-tetrahydrocannabinol (carboxy-THC) to creatinine ratio along with a...
Multicenter Collaboration Defends against Vector-Borne Diseases - Insights
Teamwork is critical among staff from Mayo Clinic, the Centers for Disease Control and Prevention, Minnesota Department of Health, and the University of Wisconsin-Madison in order to keep tabs on tick trends and defend against vector-borne...
Surprises in Coagulation Testing - Insights
In this “Hot Topic,” William Nichols, M.D., presents a case study that demonstrates how pre- and postanalytic variables of the patient and blood samples can have confounding effects on the laboratory evaluation of coagulation disorders.
NGS for Myeloid Neoplasm Evaluation - Insights
In this month's "Hot Topic," David Viswanatha, M.D., discusses updates to Mayo Clinic's next-generation sequencing (NGS) for myeloid neoplasm evaluation, involving new test targets, the rationale for new genetic regions, alignments with the...
In this month's "Hot Topic," Brad Karon, M.D., Ph.D., reviews pediatric venipuncture volumes in this year’s Phlebotomy Top Gun case-based presentation as requested by previous Phlebotomy conference attendees.
PD-L1 Testing by Immunohistochemistry - Insights
In this month's "Hot Topic," Anja Roden, M.D., discusses the role of PD-L1 interaction in the immune system, challenges of PD-L1 testing, and current PD-L1 companion testing in various tumor types.