FISH testing helps detect unseen cancer cells: Shannon Camlek - Insights
On the brink of losing her battle with acute myeloid leukemia, Shannon Camlek arrived at Mayo Clinic as a last hope. Her chances didn’t look good, but with the help of specialized genetic testing, particularly FISH (fluorescence in situ...
March 2023 - Clinical Biochemistry - Insights
This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Biochemistry.
Heparin Induced Thrombocytopenia (HIT) and the Role of Serotonin Release Assay (SRA) - Insights
In this month's "Hot Topic," Rajiv Pruthi, M.B.B.S., discusses heparin induced thrombocytopenia (HIT), approach diagnosis, and the role of the functional serotonin release assay (SRA).
Familial Variant Targeted Testing (FMTT) - Insights
In this month's "Hot Topic," Megan Hoenig, M.S., M.P.H., CGC, a licensed and certified genetic counselor with the Division of Laboratory Genetics and Genomics at Mayo Clinic Laboratories, describes the principles and benefits of Familial...
Diagnostic Guidelines for Celiac Disease - Insights
In this "Hot Topic," Melissa Snyder, Ph.D., provides a brief review of published guidelines for the diagnosis of celiac disease, with a specific focus on the role of laboratory testing.
A "sandbox" for innovation: The Advanced Diagnostics Laboratory - Insights
Mayo Clinic’s Advanced Diagnostics Laboratory (ADL) is a visionary space designed to foster innovation. The ADL has a direct impact on patient lives, bringing promising tests and services to patients at Mayo and around the world.
Surprises in Coagulation Testing - Insights
In this “Hot Topic,” William Nichols, M.D., presents a case study that demonstrates how pre- and postanalytic variables of the patient and blood samples can have confounding effects on the laboratory evaluation of coagulation disorders.
Lyme Disease, Part 2: Borrelia mayonii-A New Cause of Lyme Disease in Upper Midwest - Insights
In this “Hot Topic,” Bobbi Pritt, M.D., discusses how Lyme disease is the most common vector-borne illness in the United States and Europe and caused primarily by Borrelia burgdorferi in the United States, while B burgdorferi, B afzelii,...
Congenital disorders of glycosylation - Insights
In this month’s “Hot Topic,” Gessi Pino, a genetic counselor in the Biochemical Genetics Lab at Mayo Clinic, and Kimiyo Raymond, M.D., a clinical consultant in the laboratory and an expert in Congenital Disorders of Glycosylation (CDG),...
Autoimmune Encephalitis Misdiagnosis - Insights
In this month's "Hot Topic," Eoin Flanagan, M.B., B. Ch., discusses the important issue of autoimmune encephalitis misdiagnosis and identifies red flags that be useful in clinical practice to suggest alternative diagnoses and highlight...