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Mayo Clinic Laboratory and pathology research roundup: November 1 - Insights

This week's research roundup features: Alliance A071401: phase II trial of focal adhesion kinase inhibition in meningiomas with somatic NF2 mutations

Mayo Clinic Laboratory and pathology research roundup: October 4 - Insights

This week's research roundup features: Tumor microenvironment CD14+ cells correlate with poor overall survival in patients with early-stage lung adenocarcinoma

Mayo Clinic Laboratory and pathology research roundup: September 13 - Insights

This week's research roundup features: A simple score to identify increased risk of transthyretin amyloid cardiomyopathy in heart failure with preserved ejection fraction

Mayo Clinic Laboratory and pathology research roundup: November 8 - Insights

This week's research roundup features: Evaluating the significance of pancreatobiliary fluorescence in situ hybridization polysomy on prognosis in de novo cholangiocarcinoma

Mayo Clinic Laboratory and Pathology Research Roundup: Jan. 28 - Insights

This week’s Research Roundup highlights the diagnostic accuracy of echocardiography and intraoperative surgical inspection of the unicuspid aortic valve.

Mayo Clinic Laboratory and pathology research roundup: October 18 - Insights

This week's research roundup features: How do I warm HPC(A) products to maximize cell viability in the setting of cold agglutinin disease?

Mayo Clinic Laboratory and pathology research roundup: August 23 - Insights

This week's research roundup features: High-sensitivity cardiac troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR guidelines for the evaluation and diagnosis of acute chest pain

Mayo Clinic Laboratory and pathology research roundup: October 11 - Insights

This week's research roundup features: Transcriptomic analysis of cirrhosis-like hepatocellular carcinoma reveals distinct molecular characteristics and pathologic staging implications

Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 25 - Insights

This week’s Research Roundup highlights rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease.

Mayo Clinic Laboratory and Pathology Research Roundup: Dec. 11 - Insights

This week’s Research Roundup highlights the association between microinfarcts and blood pressure trajectories.

Mayo Clinic Laboratory and Pathology Research Roundup: July 3 - Insights

This week’s Research Roundup highlights the comparison of gadolinium concentrations within multiple rat organs after intravenous administration of linear versus macrocyclic gadolinium chelates.

Mayo Clinic Laboratory and Pathology Research Roundup: June 18 - Insights

This week’s Research Roundup features highly discriminant methylated DNA markers for the non-endoscopic detection of Barrett's esophagus.

Mayo Clinic Laboratory and pathology research roundup: July 5 - Insights

This week’s research roundup features: The publication impact of the first 100 THOR Network publications by bibliometric and social network analyses. 

Mayo Clinic Laboratory and pathology research roundup: August 2 - Insights

This week's research roundup features: Gastrointestinal stromal tumors mimicking gynecologic disease: clinicopathological analysis of 20 cases.

Mayo Clinic Laboratory and pathology research roundup: July 26 - Insights

This week's research roundup features: Motor-neuron-disease-like phenotype associated with IgLON5 disease.

Mayo Clinic Laboratory and pathology research roundup: June 21 - Insights

Featured Abstract: A dynamic 3-factor survival model for acute myeloid leukemia that accounts for response to induction chemotherapy.

Allan Jaffe, M.D., Discusses Use of Highly Sensitive Cardiac Troponin in CAP Today - Insights

Allan Jaffe, M.D., Consultant and Chair of Mayo Clinic’s Division of Clinical Core Laboratory Services, with a joint appointment in the Division of Cardiovascular Diseases, spoke with CAP Today about what a new higher-sensitivity cardiac...

Mayo Clinic Laboratories Mobilizes for Thousands of Plasma Samples from COVID-19 Survivors - Insights

As Amy Ennis put her daughter down for a nap on a Saturday afternoon, she received a call from work. More than 5,000 specimens would soon be arriving at Rochester International Airport (RST) for plasma testing. The logistics involved in the...

Welcome 2017–18 Residents and Fellows - Insights

The Department of Laboratory Medicine and Pathology would like to take the opportunity to welcome the new residents and fellows to the department.

A Home for the Iconic Mayo Brothers Statue #ThrowbackThursday - Insights

When construction crews broke ground on an expansion project for the Mayo Civic Center in Rochester, Minnesota, in 2015, one of the earliest decisions they and the City of Rochester faced was deciding what to do with the iconic bronze...

Congrats to 2017 Residency and Fellowship Program Graduates - Insights

On June 14, a ceremony was held in honor of 36 graduating Mayo Clinic Residency and Fellowship Program trainees. At the event, administrators, program directors, associate program directors, consultants, and education staff celebrated the...

Ross Reichard, M.D., Named DLMP Vice Chair of Quality and Associate Chair of Practice - Insights

Ross Reichard, M.D., has been appointed the new Department of Laboratory Medicine and Pathology (DLMP) Vice Chair of Quality and Associate Chair of Practice, effective June 28, 2017. These two leadership positions were created by the DLMP...

Kevin Halling, M.D., Ph.D., Panelist on Minnesota Health Care Roundtable about Precision Medicine - Insights

As published in the summer issue of Minnesota Physician, Kevin Halling, M.D., Ph.D., Co-Director of the Genomics Laboratory, recently participated in the 47th session of the Minnesota Health Care Roundtable. The topic was, “Precision...

Jane Hermansen Discusses Empowering Lab Leaders in Medical Laboratory Observer - Insights

Jane Hermansen, Network Manager at Mayo Medical Laboratories, and current President of CLMA, recently participated in an interview featured in "Medical Laboratory Observer" about empowering laboratory leaders to achieve excellence.

Remembering Nancy Reagan and a "Magical Friendship" #ThrowbackThursday - Insights

Nancy Reagan liked to say she had a "magical friendship" with Mayo Clinic, since it was a future surgeon's sleight-of-hand that introduced her to the institution. Mrs. Reagan, who died March 6, 2016, was a loyal Mayo patient and advocate...

Baseball Signed by Lou Gehrig Highlights Mayo History #ThrowbackThursday - Insights

In 1939, in Rochester, Minnesota, a young man named Robert Tierney was playing second base for the city's American Legion baseball team when he crossed paths with another of the game's all-time greats: The Iron Horse himself, Lou Gehrig.

February 2023 - Clinical Informatics - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Informatics.

Mayo Clinic Laboratory and Pathology Research Roundup: Dec. 24 - Insights

This week’s Research Roundup determines the clinical validity of hereditary colorectal cancer and polyposis susceptibility genes using the clinical genome resource clinical validity framework.

Joseph Maleszewski, M.D., on Gene Testing in Cardiomyopathy Analysis in CAP Today - Insights

At the annual meeting of the Association for Molecular Pathology this past November, Joseph Maleszewski, M.D., a cardiovascular pathologist and Professor of Laboratory Medicine and Pathology at Mayo Clinic in Rochester, Minnesota, presented...

Mayo Clinic Laboratory and Pathology Research Roundup: March 12 - Insights

This week’s Research Roundup highlights cardiovascular concerns in BRCA1 and BRCA2 mutation carriers.

Phlebotomy Modules: Module 1 | Insights

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Mayo Clinic Laboratory and Pathology Research Roundup: May 14 - Insights

This week’s Research Roundup highlights potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations.

Mayo Clinic Laboratory and Pathology Research Roundup: June 11 - Insights

This week’s Research Roundup highlights the detection of gastric cancer with novel methylated DNA markers: discovery, tissue validation, and pilot testing in plasma.

Mayo Clinic Laboratory and pathology research roundup: March 29 - Insights

This Feature Includes: Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules.

Mayo Clinic Laboratory and pathology research roundup: March 22 - Insights

This Feature Includes: A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis.

Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 13 - Insights

This week’s Research Roundup highlights diagnostic thresholds for androgen-producing tumors or pathologic hyperandrogenism in women by use of total testosterone concentrations measured by liquid chromatography-mass spectrometry.

Mayo Clinic Laboratory and Pathology Research Roundup: July 2 - Insights

This week’s Research Roundup highlights the comparison of risk stratification models to predict recurrence and survival in pleuropulmonary solitary fibrous tumor.

Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 6 - Insights

This week’s Research Roundup highlights how a novel enhancer regulates MGMT expression and promotes temozolomide-resistance in glioblastomas.

Mayo Clinic Laboratory and Pathology Research Roundup: Feb. 26 - Insights

This week’s Research Roundup highlights the blast phase myeloproliferative neoplasm with a Mayo-AGIMM study of 410 patients from two separate cohorts.

Mayo Clinic Laboratory and Pathology Research Roundup: Feb. 19 - Insights

This week’s Research Roundup highlights the genomic analysis using regularized regression in high-grade serous ovarian cancer.

Mayo Clinic Laboratory and Pathology Research Roundup: April 23 - Insights

This week’s Research Roundup highlights different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis.

Mayo Clinic Laboratory and Pathology Research Roundup: April 16 - Insights

This week’s Research Roundup highlights the clinical and pathological phenotype of genetic causes of focal segmental glomerulosclerosis in adults.

Mayo Clinic Laboratory and pathology research roundup: October 5 - Insights

This week's research roundup features: Therapeutic trials in adult FSGS: lessons learned and the road forward.

Mayo Clinic Laboratory and Pathology Research Roundup: Jan. 1 - Insights

This week’s Research Roundup highlights multifaceted Fanconi anemia signaling.

Mayo Clinic Laboratory and Pathology Research Roundup: Jan. 29 - Insights

This week’s Research Roundup highlights pathways impacted by genomic alterations in pulmonary carcinoid tumors.

Mayo Clinic Laboratory and Pathology Research Roundup: Jan. 22 - Insights

This week’s Research Roundup highlights improving immune-vascular crosstalk for cancer immunotherapy.

Mayo Clinic Laboratory and pathology research roundup: July 12 - Insights

This week's research roundup features: PFKFB3 works on the FAK-STAT3-SOX2 axis to regulate the stemness in MPM.

Mom Knows Best When It Comes to Inspiring Blood Donation - Insights

For Doug Bodde, a Laboratory Service and Partner Development Manager in the Department of Laboratory Medicine and Pathology in Rochester, blood donation has been a part of his life since he was young.

Mayo Clinic Laboratory and Pathology Research Roundup: Nov. 27 - Insights

This week’s Research Roundup highlights distinct spatiotemporal accumulation of N-truncated and full-length amyloid-β42 in Alzheimer's disease.

Bobbi Pritt, M.D., Identifies Lyme Disease Signs and Symptoms - Insights

With tick season underway in parts of the United States, it's important to understand the signs and symptoms of Lyme disease to determine when to seek medical treatment. Bobbi Pritt, M.D., Director of the Clinical Parasitology Laboratory in...