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Widening the net to capture elusive pathogens - Insights

Central nervous system infections, such as meningitis and encephalitis, can be devastating for affected patients. While specific treatments are available for some of these infections, it first requires identifying the precise cause of...

Membranous nephropathy assay: PMND1 - Insights

John Lieske, M.D., describes Mayo Clinic Laboratories' new test for primary membranous nephropathy. PMND1 is a diagnostic cascade that provides a cost-effective approach to detecting antigens known to cause membranous nephropathy — a...

Assay finds genetic cause of low bile flow: Devin Oglesbee, Ph.D. - Insights

Devin Oglesbee, Ph.D., explains how Mayo Clinic Laboratories' cholestasis gene panel identifies mutations that cause low flow of bile from the liver. Test results help guide treatment decisions that can prevent liver damage.

IDH assay facilitates timelier leukemia treatment: Rong He, M.D. - Insights

In this test-specific episode of the "Answers From the Lab" podcast, Rong He, M.D., explains how Mayo Clinic Laboratories' IDHQ test improves upon next generation sequencing for assessing AML treatment options.

FDA-approved test expands options for Alzheimer's disease - Insights

Joshua Bornhorst, Ph.D., describes the new, FDA-approved Alzheimer's disease (AD) test and how it differs from Mayo Clinic Laboratories' existing AD evaluation. The laboratory will offer both tests, to ensure flexibility and options for...

PIK3CA assay guides treatment of progressing breast cancer - Insights

Katherine Geiersbach, M.D., explains how Mayo Clinic Laboratories' PIK3CA assay informs breast cancer treatment. The assay identifies patients eligible for a certain second-line therapy when initial treatment has failed.

Collaboration Paves the Way for Rapid Discovery in Autoimmune Neurology - Insights

Using advanced technology, scientists at Chan Zuckerberg (CZ) Biohub, Mayo Clinic and University of California, San Francisco (UCSF), have discovered an autoimmune disease that appears to affect men with testicular cancer.

Chromium and Cobalt - Insights

Paul Jannetto, Ph.D., describes Mayo Clinic Laboratories' synovial fluid testing for patients with symptoms of failed hip arthroplasty. The Food and Drug Administration recommends testing for elevated chromium and cobalt, which can indicate...

Our staff, our stories: Ahmed and Alison Bashier - Insights

Looking back on their wedding, the Bashiers feel the event was a shining example of how greater empathy and understanding can be fostered between two very different cultures via a communal exchange of customs and traditions on an intimate...

University of Louisville: Building an evidence-based algorithm to guide autoimmune neurology patient care - Insights

UofL Health – UofL Hospital physicians and laboratory scientists faced challenges in the ordering of autoimmune and paraneoplastic panels: duplicate orders that add unnecessary cost and omitted test orders that could provide the key to the...