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What's New in Health Care Reform: Feb. 13 - Insights

Top highlights include: College education doesn't protect against Alzheimer's, A.I. shows promise as a physician assistant, how machine learning is crafting precision medicine, CVS introduces new concept store with more health care, and...

A decade-long search for answers ends at Mayo Clinic: Tyler Hart - Insights

After years of misdiagnosis, Tyler Hart found answers at Mayo Clinic, discovering he had NF155-IgG4 autoimmune nodopathy instead of CIDP

MCL @Work: Jane Hermansen - Insights

Outreach manager Jane Hermansen regards Mayo Clinic as the pinnacle of healthcare. Having spent her formative years in Minnesota, she was inspired by her uncle Roger to embark on a path as a laboratory scientist. Presently, she oversees the...

Cytomegalovirus Antiviral Resistance Testing: A New Assay for Detection of Mutations Associated with Antiviral Resistance in CMV - Insights

Cytomegalovirus, or CMV, is a common cause of disease in the transplant population. In some patients who are diagnosed with CMV and are on antiviral treatment for infections, the virus may develop resistance to the drugs. This “Hot Topic”...

Pathways Case Studies: December 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for December include the following sub-specialties: Cardiovascular Pathology and...

Calprotectin and Inflammatory Bowel Disease - Insights

The differential diagnosis for inflammatory bowel disease (IBD) includes irritable bowel syndrome (IBS). While the clinical presentation is similar, IBD is an inflammatory disease, while IBS is a noninflammatory disease. View this "Hot...

MSA Patient Holds Steady Following Small Group Study of Stem Cell Therapy - Insights

Steve Day experiences balance issues, sleeping problems, and irregular blood pressure stem from a rare, unusual neurodegenerative disease—multiple system atrophy. Read his story.

The Collective Wisdom of Biobanks - Insights

Since ancient times, physicians have analyzed patient specimens to diagnose illness. Now, our samples can do far more than diagnose. They can help researchers find treatments for the unmet needs of patients.

Our staff, our stories: Andrew "Roo" Yori - Insights

Andrew “Roo” Yori’s persistence and athletic gifts allowed him to achieve his dream of becoming an American Ninja Warrior in 2016.

Applying the Staffing-to-Workload Methodology: Basic Staffing Model - Insights

Mike Baisch, Systems Engineer at Mayo Clinic, discusses how to apply the staffing-to-workload methodology to a series of case studies. This post highlights a “basic” staffing model.

Amid COVID-19 upheaval, DLMP staff steps up - Insights

When COVID-19 hit, staff in Laboratory Medicine and Pathology at Mayo Clinic rose to the challenge with perseverance, flexibility, and resilience.

A web of care, close to home: Support on the cancer journey - Insights

Dr. Dollahite received world-class cancer treatment from a web of health care organizations, including Mayo Clinic in Rochester, Minnesota. Yet she never left New York; most of her treatment occurred in Ithaca. What made that possible was...

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) - Insights

In this month's "Hot Topic," Eoin Flanagan, M.B., B.Ch., reviews the recent diagnostic criteria for Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD).

Multiplex PCR for Microbial Detection in Spinal Fluid (BIOFIRE FILMARRAY Meningitis/Encephalitis Panel) - Insights

In this month’s “Hot Topic,” Robin Patel, M.D., discusses the FilmArray meningitis/encephalitis (ME) panel, describing the panel, her experience with it, and an algorithm for its use.

Rare patient case helps inform and validate GABA-A-R antibody encephalitis testing: JoAnne Michael - Insights

JoAnne Michael’s symptoms started with dizziness and forgetfulness before down spiraling into severe confusion, crying jags, and brain seizures. ER doctors at her local hospital initially thought she was on drugs. JoAnne, terrified,...

Autoimmune Encephalopathy Testing - Mayo Clinic Laboratories

Our phenotype specific testing for autoimmune encephalopathy contains only clinically relevant antibodies providing accurate answers for treatment guidance.

Autoimmune Encephalopathy Testing - Mayo Clinic Laboratories

Our phenotype specific testing for autoimmune encephalopathy contains only clinically relevant antibodies providing accurate answers for treatment guidance.

Antibody Prevalence in Epilepsy and Encephalopathy (APE2) Score - Insights

In this month’s “Hot Topic,” Divyanshu Dubey, M.B.B.S., discusses how patients with encephalopathy and/or epilepsy of unknown etiology may have an autoimmune or paraneoplastic cause.

Classical Hematology 2023 - Insights

This Mayo Clinic conference will address the approach to the evaluation of frequently encountered blood count abnormalities. It will also provide an update on the diagnosis and management of common and rare nonmalignant blood disorders....

Classical Hematology 2023 - Insights

This Mayo Clinic conference will address the approach to the evaluation of frequently encountered blood count abnormalities. It will also provide an update on the diagnosis and management of common and rare nonmalignant blood disorders....

Classical Hematology 2023 - Insights

This Mayo Clinic conference will address the approach to the evaluation of frequently encountered blood count abnormalities. It will also provide an update on the diagnosis and management of common and rare nonmalignant blood disorders....

Classical Hematology 2023 - Insights

This Mayo Clinic conference will address the approach to the evaluation of frequently encountered blood count abnormalities. It will also provide an update on the diagnosis and management of common and rare nonmalignant blood disorders....

Classical Hematology 2023 - Insights

This Mayo Clinic conference will address the approach to the evaluation of frequently encountered blood count abnormalities. It will also provide an update on the diagnosis and management of common and rare nonmalignant blood disorders....

Classical Hematology 2023 - Insights

This Mayo Clinic conference will address the approach to the evaluation of frequently encountered blood count abnormalities. It will also provide an update on the diagnosis and management of common and rare nonmalignant blood disorders....

Classical Hematology 2023 - Insights

This Mayo Clinic conference will address the approach to the evaluation of frequently encountered blood count abnormalities. It will also provide an update on the diagnosis and management of common and rare nonmalignant blood disorders....

Classical Hematology 2023 - Insights

This Mayo Clinic conference will address the approach to the evaluation of frequently encountered blood count abnormalities. It will also provide an update on the diagnosis and management of common and rare nonmalignant blood disorders....

Classical Hematology 2023 - Insights

This Mayo Clinic conference will address the approach to the evaluation of frequently encountered blood count abnormalities. It will also provide an update on the diagnosis and management of common and rare nonmalignant blood disorders....

Platelet Transmission Electron Microscopy and Flow Cytometry - Insights

In this "Hot Topic," Dong Chen, M.D., Ph.D., describes how flow cytometry, electron micrographic study, and molecular testing are used to diagnose platelet function disorders.

QuantiFERON-TB Gold Plus - Insights

In this month’s “Hot Topic,” Elitza Theel, Ph.D. will discuss a new interferon-gamma release assay that can assist in the detection of individuals that are infected with tuberculosis.

MASS-FIX - Insights

Learn more about matrix-assisted laser desorption/ionization-time of flight mass spectrometry and the identification of plasma cell disorders.

Antibody Prevalence in Epilepsy and Encephalopathy (APE2) Score - Insights

In this month’s “Hot Topic,” Divyanshu Dubey, M.B.B.S., discusses how patients with encephalopathy and/or epilepsy of unknown etiology may have an autoimmune or paraneoplastic cause.

MASS-FIX - Insights

Learn more about matrix-assisted laser desorption/ionization-time of flight mass spectrometry and the identification of plasma cell disorders.

Pathways Case Studies: January 2023 - Insights

This "Pathways" program provides Anatomic and Clinical Pathology cases that include a history, potential answers, rationale, and relevant references. Cases for January include the following sub-specialties: Bone and Soft Tissue Pathology,...

Phlebotomy Top Gun: Safe Handling of Laboratory Specimens During the COVID-19 Pandemic - Insights

In this month’s “Hot Topic,” Brad Karon, M.D., Ph.D., addresses the safe handling of laboratory specimens submitted during the COVID-19 pandemic through his yearly Phlebotomy Top Gun presentation based on the previous year’s Phlebotomy...

New tests launched in January - Insights

In January 2023, Mayo Clinic Laboratories announced fifty-nine new tests along with numerous reference value changes, obsolete tests, and algorithm changes.

Chromogenic Factor VIII and IX Assays: Impact on Diagnosis and Management of Hemophilia - Insights

In this month’s “Hot Topic,” Rajiv Pruthi, M.B.B.S., will discuss different types of hemophilia along with their pathologic basis. He will also cover various types of factor assays such as one stage and chromogenic factor assays for...

18th Bleeding and Thrombosing Diseases - Insights

This conference will provide reviews and updates about the laboratory and clinical aspects of bleeding and thrombosing disorders. Informational presentations will be supplemented with panel discussions and case presentations, followed by...

18th Bleeding and Thrombosing Diseases - Insights

This conference will provide reviews and updates about the laboratory and clinical aspects of bleeding and thrombosing disorders. Informational presentations will be supplemented with panel discussions and case presentations, followed by...

18th Bleeding and Thrombosing Diseases - Insights

This conference will provide reviews and updates about the laboratory and clinical aspects of bleeding and thrombosing disorders. Informational presentations will be supplemented with panel discussions and case presentations, followed by...

18th Bleeding and Thrombosing Diseases - Insights

This conference will provide reviews and updates about the laboratory and clinical aspects of bleeding and thrombosing disorders. Informational presentations will be supplemented with panel discussions and case presentations, followed by...

18th Bleeding and Thrombosing Diseases - Insights

This conference will provide reviews and updates about the laboratory and clinical aspects of bleeding and thrombosing disorders. Informational presentations will be supplemented with panel discussions and case presentations, followed by...

18th Bleeding and Thrombosing Diseases - Insights

This conference will provide reviews and updates about the laboratory and clinical aspects of bleeding and thrombosing disorders. Informational presentations will be supplemented with panel discussions and case presentations, followed by...

18th Bleeding and Thrombosing Diseases - Insights

This conference will provide reviews and updates about the laboratory and clinical aspects of bleeding and thrombosing disorders. Informational presentations will be supplemented with panel discussions and case presentations, followed by...

18th Bleeding and Thrombosing Diseases - Insights

This conference will provide reviews and updates about the laboratory and clinical aspects of bleeding and thrombosing disorders. Informational presentations will be supplemented with panel discussions and case presentations, followed by...

18th Bleeding and Thrombosing Diseases - Insights

This conference will provide reviews and updates about the laboratory and clinical aspects of bleeding and thrombosing disorders. Informational presentations will be supplemented with panel discussions and case presentations, followed by...

Applying the Staffing-to-Workload Methodology: Same-Day Testing Staffing Model - Insights

Mike Baisch, Principal Systems Engineer at Mayo Clinic, discusses how to apply the staffing-to-workload methodology to accommodate same-day testing requirements.

March 2023 - Clinical Biochemistry - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Biochemistry.

Surprises in Coagulation Testing - Insights

In this “Hot Topic,” William Nichols, M.D., presents a case study that demonstrates how pre- and postanalytic variables of the patient and blood samples can have confounding effects on the laboratory evaluation of coagulation disorders.

Phlebotomy Top Gun - Insights

In this month's "Hot Topic," Brad Karon, M.D., Ph.D., reviews pediatric venipuncture volumes in this year’s Phlebotomy Top Gun case-based presentation as requested by previous Phlebotomy conference attendees.

Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry in Clinical Microbiology - Insights

In this month’s “Hot Topic,” Robin Patel, M.D., discusses how matrix-assisted laser desorption ionization time of flight (MALDI TOF) mass spectrometry works for bacterial identification, including the strengths and limitations of this...