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A journey to diagnosis: One patient's story of resilience and hope - Insights
For many, the path to a correct diagnosis can be long and filled with uncertainty. This story highlights the resilience and determination of one patient who navigated a complex medical journey to find answers and hope at Mayo Clinic. The...
A novel testing approach for newly identified VEXAS syndrome - Insights
VEXAS syndrome is a severe autoinflammatory disease that results in a spectrum of rheumatologic and hematologic conditions. The underlying cause of newly identified VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome —...
A journey to diagnosis: One patient's story of resilience and hope - Insights
For many, the path to a correct diagnosis can be long and filled with uncertainty. This story highlights the resilience and determination of one patient who navigated a complex medical journey to find answers and hope at Mayo Clinic. The...
Antifungal Drug Susceptibility Testing of Yeast: A Primer for Beginners - Insights
In this month’s “Hot Topic,” Nancy Wengenack, Ph.D., discusses susceptibility testing of yeast for those who are considering performing it in their laboratory, perhaps for the first time, or for those who choose to send their yeast isolates...
Clinical microbiology at Mayo Clinic: A look back and ahead - Insights
The field of clinical microbiology has a long and distinguished history at Mayo Clinic. Since the early 1900s, the clinical microbiology team has played important and leading roles in advancing testing and patient care.
Cytology Specimen Utilization: A Proven Approach to Genetic Sequencing - Insights
PACE/State of FL - The role of cytology specimens in molecular genetic testing, emphasizing their effectiveness in identifying biomarkers critical for targeted therapies in patients with cancer.
A web of care, close to home: Support on the cancer journey - Insights
Dr. Dollahite received world-class cancer treatment from a web of health care organizations, including Mayo Clinic in Rochester, Minnesota. Yet she never left New York; most of her treatment occurred in Ithaca. What made that possible was...
Swiftly and Safely: A Century of Transporting Patients to Mayo Clinic #ThrowbackThursday - Insights
From the horse-drawn ambulance circa 1905 to a state-of-the-art helicopter and fixed-wing services of today, Mayo Clinic has been a leader in the safe, effective transportation of patients. Watch this video to see Mayo Clinic’s journey of...
Metagenomic Sequencing - A Tool for Diagnosis of Central Nervous System Infection - Insights
PACE/State of FL - Metagenomic sequencing for diagnosing central nervous system infection. Content will be shared regarding technical details, clinical applications, and results interpretation, drawing on both current literature and...
A new comprehensive genetic panel redefines Parkinson's disease diagnosis - Insights
Mayo Clinic Laboratories introduces the Inherited Parkinson’s Disease Gene Panel (Mayo ID: PARDP), a collaborative breakthrough poised to transform Parkinson’s disease diagnosis and treatment. Led by Rodolfo Savica, M.D., Ph.D., and Zhiyv...
A New Year with Familiar Viruses: Bill Morice, M.D., Ph.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to welcome the new...
A shared journey through breast cancer: Samantha Duke and Jane Hanson - Insights
When Samantha Duke discovered she had breast cancer, she didn’t have to look far for support. Her mother Jane walked a similar path 16 years earlier. Inspired both by her mom and the strong network of healthcare physicians and professionals...
A decade-long search for answers ends at Mayo Clinic: Tyler Hart - Insights
After years of misdiagnosis, Tyler Hart found answers at Mayo Clinic, discovering he had NF155-IgG4 autoimmune nodopathy instead of CIDP
A decade-long search for answers ends at Mayo Clinic: Tyler Hart - Insights
After years of misdiagnosis, Tyler Hart found answers at Mayo Clinic, discovering he had NF155-IgG4 autoimmune nodopathy instead of CIDP
A shared journey through breast cancer: Samantha Duke and Jane Hanson - Insights
When Samantha Duke discovered she had breast cancer, she didn’t have to look far for support. Her mother Jane walked a similar path 16 years earlier. Inspired both by her mom and the strong network of healthcare physicians and professionals...
November 2019 — Cytogenetics - Insights
A 30-year-old woman suffers a miscarriage, and the product of conception is sent for cytogenetic testing to rule out cytogenetic abnormalities. A...
"Mayo Clinic Q&A" highlights Mayo Clinic Laboratories' work on COVID-19 - Insights
On the podcast, Dr. William Morice described how Mayo Clinic Laboratories quickly ramped up to meet pandemic testing needs.
Multiomics: A new model for identifying biomarkers to predict severe COVID-19 outcomes - Insights
In a groundbreaking study, Mayo Clinic investigators have developed a multiomic molecular method to predict clinical COVID-19 (SARS-CoV-2) outcomes better than traditional cytokines. Using a machine-learning-based prediction model, the team...
Antimicrobial Crisis: A Silent Threat Claiming Lives - Insights from Dr. Robin Patel - Insights
Globally, five million deaths are associated with bacterial antimicrobial resistance each year, but the complexity of the issue is there is no single solution because we need to use antibiotics. It’s about finding a different way to live...
Mayo Clinic Laboratories’ newly expanded Hereditary Pancreatitis Gene Panel is transforming how clinicians diagnose and manage a complex, often elusive disease. Developed through close collaboration between lab scientists, genetic...
Since 1992, cases of colorectal cancer have been on a slow decline, yet 52,550 people died from it in 2023. At Mayo Clinic, a cutting-edge menu of both germline (inherited genetic alterations) and somatic (tumors due to non-inherited...
A repository of Phlebotomy related education.
A 65-year-old man with history of treated anal intraepithelial neoplasia presents with new-onset diarrhea. A Papanicolaou-stained anal smear was performed...
In the fall of 2017, Shayla Polanchek, a recent recipient of a heart transplant at Mayo Clinic in Rochester, Minnesota, returned to campus to review the specimen of her old heart, the one that had been removed from her chest. She had asked...
A strong community of lab professionals: Bill Morice, M.D., Ph.D., and Susan Van Meter - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, and...
Cytomegalovirus Antiviral Resistance Testing: A New Assay for Detection of Mutations Associated with
Cytomegalovirus, or CMV, is a common cause of disease in the transplant population. In some patients who are diagnosed with CMV and are on antiviral treatment for infections, the virus may develop resistance to the drugs. This “Hot Topic”...
Lyme Disease, Part 2: Borrelia mayonii-A New Cause of Lyme Disease in Upper Midwest - Insights
In this “Hot Topic,” Bobbi Pritt, M.D., discusses how Lyme disease is the most common vector-borne illness in the United States and Europe and caused primarily by Borrelia burgdorferi in the United States, while B burgdorferi, B afzelii,...
Kelch-like protein 11 autoantibodies: A novel biomarker of testicular cancer associated neurological
The discovery of Kelch like protein 11 (KLHL11) IgG as a specific biomarker of neurological autoimmunity associated testicular germ cell tumor.
Mayo Clinic Laboratories Critical Values / Critical Results List
Clinic Laboratories Critical Values / Critical Results List DEFINITION A Critical Value / Critical Result is defined as: A value/result that represents a pathophysiological state at such variance with...
Rare patient case helps inform and validate GABA-A-R antibody encephalitis testing: JoAnne Michael -
JoAnne Michael’s symptoms started with dizziness and forgetfulness before down spiraling into severe confusion, crying jags, and brain seizures. ER doctors at her local hospital initially thought she was on drugs. JoAnne, terrified,...
Rare patient case helps inform and validate GABA-A-R antibody encephalitis testing: JoAnne Michael -
JoAnne Michael’s symptoms started with dizziness and forgetfulness before down spiraling into severe confusion, crying jags, and brain seizures. ER doctors at her local hospital initially thought she was on drugs. JoAnne, terrified,...
Specimen Integrity in the Neonatal Intensive Care Unit: A Quality Improvement Initiative - Insights
This “phlebotomy webinar” will walk learners through the quality improvement methodology and describe PDSA cycle interventions that were implemented in this unit which successfully reduced the amount of canceled labs due to specimen...
myeloproliferative_neoplasm_a_diagnostic_approach_to_peripheral_blood_evaluation.pdf
Education and Research (MFMER). All rights reserved. *A minor criterion for PV **In the appropriate clinicopathologic setting Myeloproliferative Neoplasm: A Diagnostic Approach to Peripheral Blood Evaluation...
FDA Regulation of Laboratory Developed Tests - Insights
PACE/State of FL - A brief history of the FDA’s interest in LDTs and detailing new requirements.
How Pathologists Support Successful Laboratory Outreach - Insights
A pathologist’s collaboration with the outreach team and referring physicians strengthens the program and provides the best service for patients....
A worldwide increase of the incidence of early-onset pediatric inflammatory bowel disease means more children than ever are diagnosed and treated for life-altering IBD diagnoses. However, not all children...children suspected of early-onset...
Algorithms - Mayo Clinic Laboratories
Algorithms A B C D E F G H I J
Mayo Clinic Laboratory and pathology research roundup: June 21 - Insights
Featured Abstract: A dynamic 3-factor survival model for acute myeloid leukemia that accounts for response to induction chemotherapy....
A collaborative study between Mayo Clinic and the University of Illinois debunked the previous consensus about how kidney stones grow....
Thankful for Tygh: The Derossett Family - Insights
A Mayo Clinic Laboratories newborn screening panel detects a rare disease and paves the way for life-sustaining treatment....
Mayo Clinic Laboratory and pathology research roundup: April 11 - Insights
This week's Research Roundup feature: A stress-induced cilium-to-PML-NB route drives senescence initiation....
A Mayo Clinic BioPharma Diagnostics engagement offers partners access to Mayo Clinic Laboratories’ robust library of hematology evaluations....
Antibody against the GABA-A receptor is a biomarker of autoimmune encephalopathy that occurs across the lifespan, and disproportionately affects children. In this test-specific episode of the "Answers...From the Lab" podcast, Andrew McKeon,...
Sleep Disorder Testing - Mayo Clinic Laboratories
Determining orexin-A/ hypocretin-1 levels through CSF testing provides a sensitive and specific result to guide appropriate treatment for patients....
January 2020 — Laboratory Genetics and Genomics - Insights
A 19 year old female with a complex phenotype suggestive of a mitochondrial disorder had mitochondrial DNA sequencing performed three times at an outside...
Sleep Disorder Testing - Mayo Clinic Laboratories
Determining orexin-A/ hypocretin-1 levels through CSF testing provides a sensitive and specific result to guide appropriate treatment for patients....
Hematology journal lauds HIT testing research - Insights
A study involving Mayo Clinic investigators that examined new approaches to the diagnosis of heparin-induced thrombocytopenia has been met with enthusiasm in the scientific community....
Cayuga Medical Center and Mayo Clinic Laboratories - Insights
A world-class investment Collaboration resulting in world-class, value-based patient care Achieving greatness for yourself and your patients...
July 2019 — Cardiovascular - Insights
A 50-year-old man who was known to have systemic hypertension developed sudden onset of severe back pain with associated diaphoresis. He lost...
Mayo Clinic Laboratory and pathology research roundup: September 28 - Insights
features: Effect of probiotics on incident ventilator-associated pneumonia in critically Ill patients: A randomized clinical trial....