Research Archives - Page 9 of 33 - Insights

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Mayo Clinic Laboratory and Pathology Research Roundup: June 4 - Insights

This week’s Research Roundup highlights isolated hepatic non-obstructive sinusoidal dilatation, a 20-year single center experience.

The Collective Wisdom of Biobanks - Insights

Since ancient times, physicians have analyzed patient specimens to diagnose illness. Now, our samples can do far more than diagnose. They can help researchers find treatments for the unmet needs of patients.

Using CSI-Type Technology to Unravel the Source of Bacteria - Insights

Mayo Clinic laboratory workers have a new tool to perform high tech genetic sleuthing for the source of stubborn, sometimes life-threatening bacteria.

Research Archives - Page 24 of 33 - Insights

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Mayo Clinic Laboratory and Pathology Research Roundup: May 14 - Insights

This week’s Research Roundup highlights potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations.

Research Archives - Page 26 of 33 - Insights

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Research Archives - Page 25 of 33 - Insights

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Arresting Melanoma's Molecular Drivers - Insights

Melanoma, the skin cancer often associated with sun exposure, is on the rise and has no reliable cure. Mayo Clinic is at the forefront of these efforts. The Center for Individualized Medicine is unraveling the complex behavior of melanoma...

Mayo Clinic Laboratory and Pathology Research Roundup: June 11 - Insights

This week’s Research Roundup highlights the detection of gastric cancer with novel methylated DNA markers: discovery, tissue validation, and pilot testing in plasma.

Banking on Improved Health - Insights

Just as money in the bank boosts your financial well-being, biobanks have the power to impact your health. Think of biobank samples as assets that researchers can draw upon to improve disease treatments.

Mayo Clinic Laboratory and pathology research roundup: March 29 - Insights

This Feature Includes: Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules.

Research Archives - Page 12 of 33 - Insights

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Mayo Clinic Laboratory and pathology research: May 3 - Insights

Featured abstract: An overview of the clinical presentation, pathology, and the current therapeutic approach of the main representative disorders in the spectrum of glomerulonephritis.

Mayo Clinic Laboratory and pathology research roundup: April 26 - Insights

Top highlights include: Arrhythmia variant associations and reclassifications in the eMERGE-III sequencing study.

Mayo Clinic Laboratory and pathology research roundup: May 17 - Insights

Top highlights include: Rapid exclusion of acute myocardial injury and infarction with a high sensitivity cardiac troponin T in the emergency department.

Mayo Clinic Laboratory and pathology research roundup: March 22 - Insights

This Feature Includes: A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis.

Mayo Clinic Laboratory and pathology research roundup: May 10 - Insights

Top highlights include: Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse.

Research Roundup Archives - Page 13 of 29 - Insights

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Research Roundup Archives - Page 22 of 29 - Insights

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Research Roundup Archives - Page 21 of 29 - Insights

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Mayo Clinic Laboratory and Pathology Research Roundup: July 16 - Insights

This week’s Research Roundup highlights how senolytics improve physical function and increase lifespan in old age.

Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 27 - Insights

This week’s Research Roundup highlights a mechanism for preventing asymmetric histone segregation onto replicating DNA strands.

Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 13 - Insights

This week’s Research Roundup highlights diagnostic thresholds for androgen-producing tumors or pathologic hyperandrogenism in women by use of total testosterone concentrations measured by liquid chromatography-mass spectrometry.

Mayo Clinic Laboratory and Pathology Research Roundup: July 2 - Insights

This week’s Research Roundup highlights the comparison of risk stratification models to predict recurrence and survival in pleuropulmonary solitary fibrous tumor.

Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 6 - Insights

This week’s Research Roundup highlights how a novel enhancer regulates MGMT expression and promotes temozolomide-resistance in glioblastomas.

Research Roundup Archives - Page 20 of 29 - Insights

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Mayo Clinic Laboratory and Pathology Research Roundup: July 30 - Insights

This week’s Research Roundup highlights a randomized trial of spheroid reservoir bioartificial liver in Porcine model of post-hepatectomy liver failure.

Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 3 - Insights

This week’s Research Roundup highlights biphenotypic acute leukemia versus myeloid antigen-positive ALL: Clinical relevance of WHO criteria for mixed phenotype acute leukemia.

Mayo Clinic Laboratory and Pathology Research Roundup: Feb. 26 - Insights

This week’s Research Roundup highlights the blast phase myeloproliferative neoplasm with a Mayo-AGIMM study of 410 patients from two separate cohorts.

Mayo Clinic Laboratory and Pathology Research Roundup: March 19 - Insights

This week’s Research Roundup highlights the analysis of cell-free DNA to assess risk of tumoremia following endoscopic ultrasound fine-needle aspiration of pancreatic adenocarcinomas.

Mayo Clinic Laboratory and Pathology Research Roundup: April 30 - Insights

This week’s Research Roundup highlights a model for predicting breast cancer risk in women with atypical hyperplasia.

Audrey Schuetz, M.D., Comments on First-Ever Case of Human Eye Worms - Insights

A recent article in HealthDay News reported on a case of an avid 26-year-old outdoorswoman from Oregon who became the first human ever infected by a type of eye worm previously seen only in cattle. Audrey Schuetz, M.D., Senior Associate...

Mayo Clinic Laboratory and Pathology Research Roundup: Feb. 19 - Insights

This week’s Research Roundup highlights the genomic analysis using regularized regression in high-grade serous ovarian cancer.

Mayo Clinic Laboratory and Pathology Research Roundup: April 23 - Insights

This week’s Research Roundup highlights different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis.

Mayo Clinic Laboratory and Pathology Research Roundup: April 9 - Insights

This week’s Research Roundup highlights genetic evidence for early peritoneal spreading in pelvic high-grade serous cancer.

Mayo Clinic Laboratory and Pathology Research Roundup: April 16 - Insights

This week’s Research Roundup highlights the clinical and pathological phenotype of genetic causes of focal segmental glomerulosclerosis in adults.

Mayo Clinic Laboratory and Pathology Research Roundup: April 2 - Insights

This week’s Research Roundup highlights patterns of homozygosity in patients with uniparental disomy with detection rate and suggested reporting thresholds for SNP microarrays.

Mayo Clinic Laboratory and pathology research roundup: November 23 - Insights

This week’s research roundup features: The temporal onset of the core features in dementia with Lewy bodies.

Mayo Clinic Laboratory and pathology research roundup: October 5 - Insights

This week's research roundup features: Therapeutic trials in adult FSGS: lessons learned and the road forward.

Mayo Clinic Laboratory and pathology research roundup: November 2 - Insights

This week’s research roundup features: Phase II randomized trial of transoral surgery and low-dose intensity Modulated radiation therapy in resectable p16+ locally advanced oropharynx cancer: An ECOG-ACRIN cancer research group trial...

Research Archives - Page 13 of 33 - Insights

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Mayo Clinic Laboratory and pathology research roundup: November 16 - Insights

This week’s research roundup features: Discovery of autoantibodies targeting nephrin in minimal change disease supports a novel autoimmune etiology.

Mayo Clinic Laboratory and pathology research roundup: October 19 - Insights

This week’s research roundup features: Autopsy validation of progressive supranuclear palsy-predominant speech/language disorder criteria.

Mayo Clinic Laboratory and pathology research roundup: October 12 - Insights

This week’s research roundup features: Effect of urate-elevating inosine on early Parkinson disease progression: The SURE-PD3 randomized clinical trial.

Mayo Clinic Laboratory and Pathology Research Roundup: Feb. 12 - Insights

This week’s Research Roundup highlights the prediction of oncologic outcomes in Renal cell carcinoma after surgery.

Mayo Clinic Laboratory and Pathology Research Roundup: Jan. 1 - Insights

This week’s Research Roundup highlights multifaceted Fanconi anemia signaling.

Mayo Clinic Laboratory and Pathology Research Roundup: Jan. 29 - Insights

This week’s Research Roundup highlights pathways impacted by genomic alterations in pulmonary carcinoid tumors.

Patients with Blood Cancer Precursor at Risk of Developing Cancer Even after 30 Years - Insights

Patients with monoclonal gammopathy of undetermined significance are at risk of progressing to multiple myeloma or a related cancer─even after 30 years of stability, according to findings of a study by Mayo Clinic researchers published in...

Research Test Identifies BRCA2 Gene Mutations That Lead to Breast, Ovarian Cancers - Insights

A new test developed by researchers at Mayo Clinic shows which mutations in the BRCA2 gene make women susceptible to developing breast or ovarian cancers. The research behind the test was published today in the American Journal of Human...