Chromosomal microarray better informs brain tumor diagnosis - Insights
Molecular biomarkers are a critical component in the treatment of adult and pediatric brain tumors. Robert Jenkins, M.D., Ph.D., explains how Mayo Clinic Laboratories' chromosomal microarray provides more comprehensive and accurate tumor...
Accurately characterize marijuana use through urine THC testing - Insights
Paul Jannetto, Ph.D., and Loralie Langman, Ph.D., discuss Mayo Clinic Laboratories’ new marijuana monitoring evaluation, which identifies metabolites of both delta-9 tetrahydrocannabinol (THC) and delta-8 THC to accurately identify and...
Updates Streamline Autoimmune Neurology Testing: Anastasia Zekeridou, M.D., Ph.D. - Insights
Anastasia Zekeridou, M.D., Ph.D., explains how Mayo Clinic Laboratories' updated panels and methodology boost the accuracy and efficiency of testing for three autoimmune neurology biomarkers. Early diagnosis is key to managing debilitating...
Genetic Tests Identify Risk of Irinotecan-Induced Toxicity: John Logan Black, M.D. - Insights
John Logan Black, M.D., explains how Mayo Clinic Laboratories' UGT1A1 tests (Mayo IDs: U1A1Q and UGTFZ) identify genetic variants that increase the risk of potentially life-threatening reactions to irinotecan, a chemotherapy agent.
Test detects autoimmune neurology disorders linked to cancer: Sean Pittock, M.D. - Insights
Sean Pittock, M.D., explains how Mayo Clinic Laboratories' novel Ma2 test aids diagnosis of autoimmune neurology disorders that are often caused by underlying cancer. Rapid diagnosis is key to preventing significant disability and disease.
Whole genome sequencing streamlines diagnosis - Insights
Nicole Boczek, Ph.D., and Sarah Barnett, M.S., CGC, explain how Mayo Clinic Laboratories' whole genome sequencing provides comprehensive information for rapid diagnosis of hereditary disorders.
Angela Pickart, M.S., CGC, and Emily Lauer, M.S., CGC, explain how Mayo Clinic Laboratories' multigene panel helps identify the cause of hereditary ataxia. Precise diagnosis of this complex movement disorder helps guide patient treatment...
Zhiyv (Neal) Niu, Ph.D., and Rodolfo Savica, M.D., Ph.D., explain why Mayo Clinic Laboratories' gene panel is the most comprehensive test available for inherited Parkinson's disease. The new panel covers all mutations known to cause the...
An efficient, cost-effective, fungal testing alternative: Elitza Theel, Ph.D. - Insights
Elitza Theel, Ph.D., explains how Mayo Clinic Laboratories' unique Histoplasma/Blastomyces test provides cost-effective evaluation for fungal infections that cause pulmonary illness. The assay reliably detects both Histoplasma and...
RNA test identifies large B-cell lymphoma subtypes: Lisa Rimsza, M.D. - Insights
Lisa Rimsza, M.D., explains how Mayo Clinic Laboratories' unique PM3CX test can accurately determine subtypes of large B-cell lymphoma. Precise diagnosis is critical to choosing appropriate chemotherapy.
Results report simplifies urine test interpretation: John Lieske, M.D. - Insights
John Lieske, M.D., explains why it's now easier for clinicians to pull information from Mayo Clinic Laboratories' supersaturation test report. An updated format summarizes complex information to help guide the treatment of kidney stones.
Linnea Baudhuin, Ph.D., and Kate Kotzer, M.S., CGC, describe how Mayo Clinic Laboratories' postmortem genetic tests can provide answers after a sudden unexplained cardiac death. Test results are important for managing family members' risk...
Wei Shen, Ph.D., and Rhianna Urban, M.S., CGC, explain how Mayo Clinic Laboratories' gene panel establishes a diagnosis of Lynch syndrome, which heightens the risk for several cancers. Test results can guide targeted cancer surveillance for...
Breast cancer panel halves turnaround time: Wei Shen, Ph.D. - Insights
In this test-specific episode of the "Answers From the Lab" podcast, Wei Shen, Ph.D., explains how Mayo Clinic Laboratories' new breast cancer panel provides rapid results to guide critical decisions about treatment and screening.
Urologic panels provide focused cancer testing: Sounak Gupta, M.B.B.S., Ph.D. - Insights
Sounak Gupta, M.B.B.S., Ph.D., explains how Mayo Clinic Laboratories' urologic panels efficiently inform prognosis and individualized cancer treatment. The carefully curated panels fill the void between single gene assays and large NGS...
Patients with elevated LDL or "bad" cholesterol face even greater risk if their levels of small dense LDL cholesterol are also high. Vlad Vasile, M.D., Ph.D., and Leslie Donato, Ph.D., explain how Mayo Clinic Laboratories' sdLDL-c assay...
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New gene panel enhances brain tumor profiles - Insights
Cristiane (Cris) Ida, M.D., explains how Mayo Clinic Laboratories' updated neuro-oncology gene panel provides more clinically relevant information for managing adult and pediatric brain tumors.
Novel biomarkers added to movement disorders profile - Insights
Andrew McKeon, M.B., B.Ch., M.D., explains how Mayo Clinic Laboratories' expanded movement disorders panel better identifies autoimmune conditions to guide appropriate treatment.
Identifying a precise genetic cause of hearing loss impacts clinical management. Nicole Boczek, Ph.D., and Melanie Meyer, M.S., CGC, explain how Mayo Clinic Laboratories' updated panel yields comprehensive results for optimal patient care.
Dr. Leslie Donato discusses lipid testing on ADLM's Laborastories: The Podcast - Insights
Dr. Leslie Donato recently joined “Laborastories: The Podcast,” hosted by the Association for Diagnostics & Laboratory Medicine (ADLM) president Dr. Anthony Killeen, to discuss the publication of the new ADLM lipid and lipoprotein testing...
Dr. Morice shares with Lab Manager how clinical labs can advance health equity - Insights
Clinical labs are key to advancing health equity, reducing barriers, and improving access through innovation, collaboration, and community engagement. Dr. Morice shares his thoughts in the Lab Manager article, “Health Equity Starts in the...
Mayo Clinic Laboratory and pathology research roundup: January 10 - Insights
This week's research roundup features: Drug testing in support of the diagnosis of neonatal abstinence syndrome: The current situation
Mayo Clinic Laboratory and Pathology Research Roundup: February 20 - Insights
This week's research roundup feature: Patients with dementia with Lewy bodies (DLB) may have Alzheimers disease (AD) pathology that can be detected by plasma biomarkers. Our objective was to evaluate plasma biomarkers of AD and their...
Register now to attend the 35th Leveraging the Lab Conference: Seize Tomorrow - Insights
Discover how to harness the power of your outreach program to position your organization for success at the 35th Leveraging the Laboratory: Seize Tomorrow conference, presented by Mayo Clinic Laboratories. This in-person event promises...
Mayo Clinic Laboratory and Pathology Research Roundup: February 27 - Insights
This week's research roundup feature: Both targeted therapies and immunotherapies provide benefit in resected Stage III melanoma. We hypothesized that the combination of targeted and immunotherapy given prior to therapeutic lymph node...
Mayo Clinic Laboratory and Pathology Research Roundup: March 19 - Insights
This week's research roundup feature: The revised 4th edition of the World Health Organization (WHO4R) classification lists myelodysplastic syndromes with ring sideroblasts (MDS-RS) as a separate entity with single lineage (MDS-RS-SLD) or...
Using Data-Driven, In-Person Discussions to Support Outreach Clients - Insights
In this episode of Mayo Clinic Laboratories’ “Leveraging the Laboratory” podcast, host Jane Hermansen, outreach manager at Mayo Clinic Laboratories, speaks with outreach solutions strategists Ellen Dijkman Dulkes and Brianne Newton. They...
Mayo Clinic Laboratory and Pathology Research Roundup: March 5 - Insights
This week's research roundup feature: Variants of uncertain significance (VUSs) in BRCA2 are a common result of hereditary cancer genetic testing. While more than 4,000 unique VUSs, comprised of missense or intronic variants, have been...
Oncology surveillance biomarker study enrolls patients and evaluates assay - Insights
Mayo Clinic Laboratories’ BioPharma Diagnostics team supports companies from discovery to post-market in advancing their precision medicine initiatives. In this collaboration example, learn how BioPharma Diagnostics helped a biotech company...
Gastrointestinal study collects and tests patient specimens at multiple touchpoints - Insights
Mayo Clinic Laboratories’ BioPharma Diagnostics team collaborates with biopharmaceutical, diagnostic, and other research companies to offer a wide range of laboratory testing and biopharma support for all phases of clinical trials. In this...
Mayo Clinic Laboratory and Pathology Research Roundup: February 13 - Insights
This week's research roundup feature: VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) syndrome, caused by somatic mutations in UBA1, is an autoinflammatory disorder with diverse systemic manifestations. Thrombosis is a...
Mayo Clinic Laboratory and Pathology Research Roundup: January 30 - Insights
This week's research roundup feature: Incapacitated regulatory T cells (Tregs) contribute to immune-mediated diseases. Inflammatory Tregs are evident during human inflammatory bowel disease (IBD); however, mechanisms driving the development...
Mayo Clinic Laboratory and Pathology Research Roundup: January 2 - Insights
This week's research roundup feature: Sarcomas are a recently identified group of undifferentiated round/spindle cell neoplasms with a predilection for the head and neck region.
Mayo Clinic Laboratory and Pathology Research Roundup: January 9 - Insights
This week's research roundup feature: To describe a 41-year-old woman with a history of neonatal onset multisystem inflammatory disease, on treatment with daily subcutaneous injections of 600 mg of recombinant interleukin-1 receptor...
Mayo Clinic Laboratory and Pathology Research Roundup: February 6 - Insights
This week's research roundup feature: Powassan virus (POWV) is an emerging arthropod-borne flavivirus, transmitted by Ixodes spp. ticks, which has been associated with neuroinvasive disease and poor outcomes.
Mayo Clinic Laboratory and Pathology Research Roundup: January 23 - Insights
This week's research roundup feature: Measles virus (MV) vaccine strains have shown significant preclinical antitumor activity against glioblastoma (GBM), the most lethal glioma histology. In this first in human trial (NCT00390299), a...
Mayo Clinic Laboratory and Pathology Research Roundup: January 16 - Insights
This week's research roundup feature: Understanding the incidence, causes, and trends of sudden cardiac death (SCD) among young competitive athletes is critical to inform preventive policies.
Dr. Morice details how hospitals can maximize the value of their labs - Insights
William Morice II, M.D., Ph.D., president and chief executive officer of Mayo Clinic Laboratories, is a contributing author on Nasdaq.com. In his latest article, he describes the untapped potential of hospital laboratories and how health...
When is it Cool to Drool? Oral Fluid Testing for Controlled Substance Monitoring - Insights
PACE / State of FLThis webinar will describe substance use disorders and the common laboratory tests and matrices used for controlled substance monitoring. The advantages and challenges of using oral fluid will be discussed along with how...
The Growing Crisis of Antimicrobial Resistance: Robin Patel, M.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Robin Patel, M.D., director of the Infectious Diseases Research Laboratory and co-director of the...
Alarming Increase in Dengue Cases: Elitza Theel, Ph.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, to...
Get to Know the DLMP Chair: Eric Hsi, M.D. - Insights
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Eric Hsi, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic.
Testing Archives - Page 4 of 26 - Insights
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Building an effective supply provision program - Insights
Having an efficient and effective supply provision program is a cornerstone for laboratory outreach program success. By providing adequate specimen collection supplies in compliance with current regulations, the outreach laboratory-customer...
Applying MASS-FIX to Urine Samples - Insights
In this month's "Hot Topic," David Murray, M.D., Ph.D., reviews the role of urine testing for monoclonal gammopathies and discusses Mayo Clinic’s use of MASS-FIX to replace traditional immunofixation testing.
Laboratory Testing of Bone Turnover Markers - Insights
In this “Hot Topic,” Alicia Algeciras-Schimnich, Ph.D., professor of laboratory medicine and pathology at Mayo Clinic, discusses the role of bone turnover markers in osteoporosis treatment as well as how to best interpret changes in bone...
Familial Variant Targeted Testing (FMTT) - Insights
In this month's "Hot Topic," Megan Hoenig, M.S., M.P.H., CGC, a licensed and certified genetic counselor with the Division of Laboratory Genetics and Genomics at Mayo Clinic Laboratories, describes the principles and benefits of Familial...