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Mayo Clinic Discovers Gene Mutations Linked to Pancreatic Cancer, Calls for Expanded Testing - Insights

According to Mayo Clinic research published in JAMA, six genes contain mutations that may be passed down in families, substantially increasing a person’s risk for pancreatic cancer.

Gynecological cancer - Insights

Find out how our gynecological cancer panels evaluate genes with relevance to diagnosing and treating uterine, ovarian, and endometrial cancers.

Plasma-Cell Neoplasms - Mayo Clinic Laboratories

As a pioneer in the field, Mayo Clinic plays an integral role by developing new tests to help align patients with new therapies for plasma cell disorders.

Accurately characterize marijuana use through urine THC testing - Insights

Paul Jannetto, Ph.D., and Loralie Langman, Ph.D., discuss Mayo Clinic Laboratories’ new marijuana monitoring evaluation, which identifies metabolites of both delta-9 tetrahydrocannabinol (THC) and delta-8 THC to accurately identify and...

B-cell and T-cell acute lymphoblastic leukemia - Insights

Find out how our suite of B-cell and T-cell acute lymphoblastic leukemia tests can detect genetic subgroups and assist in treatment selection.

Education - Insights

Learn more about educational offerings available to primary clients of Mayo Clinic Laboratories.

Genetics events - Insights

For more than 50 years, Mayo Clinic Laboratories has been providing meaningful results to individuals seeking genetic answers. Rare genetic disorders can be among the most difficult conditions to diagnose. To provide meaningful answers, our...

Staffing to Workload in Phlebotomy Areas: Direct Effort - Insights

Mike Baisch, Principal Systems Engineer at Mayo Clinic, discusses staffing to workload in phlebotomy areas with a focus on direct effort through time spent with a patient or patient sample.

Cytomegalovirus Antiviral Resistance Testing: A New Assay for Detection of Mutations Associated with Antiviral Resistance in CMV - Insights

Cytomegalovirus, or CMV, is a common cause of disease in the transplant population. In some patients who are diagnosed with CMV and are on antiviral treatment for infections, the virus may develop resistance to the drugs. This “Hot Topic”...

Mayo Clinic Labs @Work: Clyde Christian III - Insights

Following a connection on LinkedIn, Clyde Christian found himself drawn to Mayo Clinic and joined the Hospital Sales division of Mayo Clinic Laboratories in late May 2022. As a hospital account executive for the U.S. Great Lakes region,...

Mayo Clinic Labs @Work: Grant Elmquist - Insights

Working with Mayo Clinic BioPharma Diagnostics clients, Grant Elmquist is engaged in a wide range of activities that span research and science technology, as well as a host of disease states, all with the end goal of enhancing patient care.

Mayo Clinic Labs @Work: Deb Hagen-Moe - Insights

As manager of the department’s Education Program, Deb Hagen-Moe and her team welcome new staff to Mayo Clinic’s Department of Laboratory Medicine and Pathology. Then they continue to offer a wide range of continuing education and...

Mayo Clinic Labs @Work: Tim Plummer - Insights

Tim Plummer is an operations administrator at Mayo Clinic Laboratories supporting the Division of Anatomic Pathology. He supports his team members by providing them with tools and resources to innovate and succeed. He has worked at Mayo...

Mayo Clinic Labs @Work: Paul Schneider - Insights

As a national accounts executive for Mayo Clinic Laboratories, Paul Schneider helps to improve and advance diagnostic patient care by bringing Mayo Clinic Laboratories testing to many of the nation’s top health care systems.

Pharmacogenomics - Insights

Mayo Clinic Laboratories’ pharmacogenomic testing offers superior analytical quality, enabling targeted detection of more clinically actionable alleles than other testing.

Research Roundup Archives - Page 2 of 29 - Insights

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Research Archives - Page 2 of 33 - Insights

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June 2023 - Clinical Chemistry - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Clinical Chemistry.

Laboratory Utilization Management: Tick-Borne Disease Testing - Insights

In this month's "Hot Topic," Elitza Theel, Ph.D., will be discussing laboratory utilization management, specifically for diagnostic testing for tick-borne diseases.

Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 11 - Insights

This week’s Research Roundup highlights autologous mesenchymal stem cells, applied in a bioabsorbable matrix, for treatment of perianal fistulas in patients with Crohn's disease.

Noninvasive plasma biomarker testing provides faster answers: Alicia Algeciras-Schimnich, Ph.D. - Insights

Alicia Algeciras-Schimnich, Ph.D., discusses Mayo Clinic Laboratories’ new noninvasive plasma biomarker assay for Alzheimer’s disease, an accessible, highly accurate testing option for individuals age 50 and above who are experiencing mild...

What's New in Health Care Reform: Feb. 6 - Insights

Top highlights include: New U.S. experiments aim to create gene-edited human embryos, death-cap mushrooms are spreading across North America, daily exercise has been shown to lower blood pressure, scans show female brains remain youthful as...

Five Steps to Improve Transfusion Medicine - Insights

Blood transfusion is the most common procedure performed in hospitals in the U.S. Yet published evidence shows significant gaps in clinicians' knowledge of this critical aspect of patient care, including possible adverse reactions that can...

MASTERMIND: A Smarter Search for Microbial Diagnostics - Insights

In the war against microbes, human beings are vastly outnumbered—and losing the weapons race.

Urinary Steroid Profile Assay

Understanding the difference between benign and malignant adrenal tumors has alway been difficult; this new assay will assist with this medical challenge.

Pushing the envelope on personalized medicine - Insights

Recognizing the powerful role genes can play in diagnosing illness and guiding treatment, the Division of Laboratory Genetics and Genomics at Mayo Clinic spearheaded a testing expansion, implementing and upgrading more than 60 advanced...

Testing Archives - Page 4 of 26 - Insights

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Testing Archives - Insights

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Newborn screening - Insights

Learn more Mayo Clinic Laboratories robust menu of newborn screening testing, which includes both primary and second-tier biochemical and molecular evaluations.

Membranous nephropathy - Insights

Membranous nephropathy (MN) is one of the leading causes of nephrotic syndrome in adults. Our menu of clinically validated assays assists with diagnosis, monitors disease progression, and guides clinical outcomes.

Rheumatology - Insights

Testing for systemic lupus erythematosus (SLE) and related antiphospholipid syndrome (APS) at Mayo Clinic Laboratories is performed by experienced laboratory scientists and testing experts with decades of experience diagnosing autoimmune...

Urologic cancer - Insights

Learn about how our testing for patients with renal, bladder, and prostate cancer identifies the cancer’s genetic traits and helps direct treatment.

Oral fluid panel - Insights

Find out more about our cost-effective immunoassay panel, which uses oral fluid testing to support addiction treatment and pain management.

Metagenomics - Insights

Mayo Clinic Laboratories cerebrospinal fluid metagenomic testing uses shotgun metagenomic sequencing to interrogate all microbial DNA and RNA present in a sample and determine the presence of potential pathogens.

Rapid response: COVID-19, monkeypox, and whatever comes next - Insights

Mayo Clinic Laboratories' rapid response to public health threats has been honed during outbreaks of viruses like 2009’s H1N1 influenza, Zika, Ebola and, most recently, COVID-19. Before COVID-19, laboratory staff were already experts in...

Comprehensive panel boosts GIST diagnosis sensitivity - Insights

Rondell Graham, M.B.B.S., describes Mayo Clinic Laboratories' new assay for gastrointestinal stromal tumors, or GIST. The panel covers multiple mutations, to better inform diagnosis and treatment options.

One Test, Multiple Targets: Zeroing in on Autoimmune Movement Disorders - Insights

A movement disorder might be caused by the body’s immune system, which is meant to fight infections, suddenly attacking the brain. Fortunately, an “autoimmune movement disorder” can often be treated—once its cause is discovered.

Calprotectin and Inflammatory Bowel Disease - Insights

The differential diagnosis for inflammatory bowel disease (IBD) includes irritable bowel syndrome (IBS). While the clinical presentation is similar, IBD is an inflammatory disease, while IBS is a noninflammatory disease. View this "Hot...

Amid COVID-19 upheaval, DLMP staff steps up - Insights

When COVID-19 hit, staff in Laboratory Medicine and Pathology at Mayo Clinic rose to the challenge with perseverance, flexibility, and resilience.

Autoimmune Encephalopathy Testing - Mayo Clinic Laboratories

Our phenotype specific testing for autoimmune encephalopathy contains only clinically relevant antibodies providing accurate answers for treatment guidance.

Lyme Disease, Part 2: Borrelia mayonii-A New Cause of Lyme Disease in Upper Midwest - Insights

In this “Hot Topic,” Bobbi Pritt, M.D., discusses how Lyme disease is the most common vector-borne illness in the United States and Europe and caused primarily by Borrelia burgdorferi in the United States, while B burgdorferi, B afzelii,...

Autoimmune Encephalopathy Testing - Mayo Clinic Laboratories

Our phenotype specific testing for autoimmune encephalopathy contains only clinically relevant antibodies providing accurate answers for treatment guidance.

Genetic Testing to Enhance Multiple Myeloma Treatment - Insights

Multiple myeloma is the second most common blood cancer, but most people haven’t heard of it until they or someone they know is diagnosed with the disease. March is Myeloma Action Month—a time to focus attention on the fight against...

January 2023 - Biochemical Genetics - Insights

This "Pathways" program provides a Clinical Pathology case that includes a history, potential answers, rationale, and relevant references. This case sub-specialty is Biochemical Genetics.

Seeking, and finding, answers, comfort, and hope: Joe Mondloch - Insights

Joe Mondloch and his wife Sue have existed in a grey area of uncertainty due to the unpredictable autoimmune neurological illness Joe has lived with for the last seven years. Rare, incurable, and debilitating, the newly classified disorder...

NGS for Myeloid Neoplasm Evaluation - Insights

In this month's "Hot Topic," David Viswanatha, M.D., discusses updates to Mayo Clinic's next-generation sequencing (NGS) for myeloid neoplasm evaluation, involving new test targets, the rationale for new genetic regions, alignments with the...

New test distinguishes between prion disease and other causes of rapidly progressive dementia - Insights

Performed on cerebrospinal fluid, Mayo Clinic’s RT-QuIC prion test can distinguish prion disease from other types of rapidly progressive dementias to enhance patient care.

High-Resolution Targeted Benzodiazepine Screen - Insights

In this “Hot Topic,” Paul Jannetto, Ph.D., highlights Mayo Clinic’s targeted benzodiazepine assay and discusses the advantages and limitations of various urine-screening assays as well as quantitative confirmatory testing to determine...

Gadolinium Accumulation in Brain Tissue following Contrast-Enhanced MRI Has Not Been Shown to Have Harmful Side Effects - Insights

Gadolinium-based contrast agents (GBCAs) have revolutionized MRIs by increasing the clinical utility and detection sensitivity of these exams. GBCAs also contain gadolinium, a rare earth metal with unique chemical properties. This article...

Register today for Leveraging the Laboratory: Dimensions of Outreach - Insights

Are you looking to take your laboratory's outreach program to the next level? Our outreach conference will provide innovative views into all aspects of health system laboratory outreach programs. This exciting event will be held Sept....