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Mayo Clinic Laboratory and Pathology Research Roundup: May 8 - Insights

This week’s Research Roundup highlights how AKT-phosphorylated FOXO1 suppresses ERK activation and chemoresistance by disrupting IQGAP1-MAPK interaction.

Mayo Clinic Laboratory and Pathology Research Roundup: December 12 - Insights

This week's research roundup feature: Most patients with solitary bone plasmacytomas (SBP) progress to multiple myeloma (MM) after definitive radiation therapy as their primary treatment. Whether the presence of high-risk (HR) cytogenetic...

Mayo Clinic Laboratory and Pathology Research Roundup: January 16 - Insights

This week's research roundup feature: Understanding the incidence, causes, and trends of sudden cardiac death (SCD) among young competitive athletes is critical to inform preventive policies.

History of Mayo Clinic School of Graduate Medical Education #ThrowbackThursdays - Insights

Ever since Mayo Clinic was established, the institution's goal has been to provide outstanding care to its patients and offer superior education programs that ensure the success of the next generation of medical professionals. Read more...

Week in Review: October 4 - Insights

Top highlights include: Flu vaccine information, possible effects that red meat has on the human body, and what vaping does to the lungs.

Week in Review: October 18 - Insights

Top highlights include: scientists continue to investigate mysterious vaping illnesses, a possible vaccine for breast cancer could be available in less than a decade, and determining if patients are sick from the flu or from vaping.

Week in Review: October 11 - Insights

Top highlights include: Discussions around flu season, teen vaping, spotting signs of cognitive impairment, and DNA tests.

Mayo Clinic Laboratory and Pathology Research Roundup: Nov. 13 - Insights

This week’s Research Roundup highlights how the DnaJ heat shock protein family B member 9 is a novel biomarker for fibrillary GN.

Mayo Clinic Laboratory and Pathology Research Roundup: Dec. 10 - Insights

This week’s Research Roundup highlights the evaluation of monoclonal gammopathy of renal significance: A consensus report of the International Kidney and Monoclonal Gammopathy Research Group.

Mayo Clinic Laboratory and pathology research roundup: November 15 - Insights

This week's research roundup features: Renin production by juxtaglomerular cell tumors and clear cell renal cell carcinoma and the role of angiotensin signaling inhibitors

Mayo Clinic Laboratory and pathology research roundup: September 20 - Insights

This week's research roundup features: Into the future: a pilot study combining imaging with molecular profiling to predict resectability in ovarian cancer

Mayo Clinic Laboratory and Pathology Research Roundup: July 31 - Insights

This week’s Research Roundup highlights urinary extracellular vesicles of podocyte origin and renal injury in preeclampsia.

Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 14 - Insights

This week’s Research Roundup highlights how human gut-derived commensal bacteria suppresses central nervous system inflammatory and demyelinating disease.

Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 11 - Insights

This week’s Research Roundup highlights autologous mesenchymal stem cells, applied in a bioabsorbable matrix, for treatment of perianal fistulas in patients with Crohn's disease.

Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 9 - Insights

This week’s Research Roundup highlights a subset of well-differentiated hepatocellular carcinomas that are arginase-1 negative.

Mayo Clinic Laboratory and Pathology Research Roundup: July 10 - Insights

This week’s Research Roundup highlights the association of postoperative high-sensitivity troponin levels with myocardial injury and 30-day mortality among patients undergoing noncardiac surgery.

Mayo Clinic Laboratory and Pathology Research Roundup: June 5 - Insights

This week’s Research Roundup highlights oncologic outcomes for patients with residual cancer at cystectomy following neoadjuvant chemotherapy.

Mayo Clinic Laboratory and Pathology Research Roundup: June 19 - Insights

This week’s Research Roundup highlights the single-nephron glomerular filtration rate in healthy adults.

Mayo Clinic Laboratory and Pathology Research Roundup: May 15 - Insights

This week’s Research Roundup highlights how the androgen receptor variant AR-V9 is co-expressed with AR-V7 in prostate cancer metastases and predicts abiraterone resistance.

Mayo Clinic Laboratory and Pathology Research Roundup: July 17 - Insights

This week’s Research Roundup highlights postoperative stereotactic radiosurgery compared with whole brain radiotherapy for resected metastatic brain disease.

Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 2 - Insights

This week’s Research Roundup highlights immune-mediated autonomic neuropathies following allogeneic stem cell transplantation in acute myeloid leukemia.

Mayo Clinic Laboratory and pathology research roundup: August 16 - Insights

This week's research roundup features: Identification of caveolae-associated protein 4 autoantibodies as a biomarker of immune-mediated rippling muscle disease in adults.

Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 20 - Insights

This week’s Research Roundup highlights how fasting blood glucose levels provide an estimate of duration and progression of pancreatic cancer before diagnosis.

Mayo Clinic Laboratory and Pathology Research Roundup: July 23 - Insights

This week’s Research Roundup highlights gastrointestinal and extra-intestinal manifestations of immunoglobulin G4-related disease.

1907: The First Plummer Project #ThrowbackThursday - Insights

The successful launch of Epic at Mayo Clinic Health System sites in Wisconsin on July 8 recalls another milestone 110 years ago. On July 19, 1907, patient No. 1 registered in the new system designed by Henry Plummer, M.D., in collaboration...

Mayo Now Has Two Ninjas in the House - Insights

Candace Granberg, M.D., has a lot of titles, including surgeon, wife, mom, and volunteer. Now, she can add another: ninja warrior. The pediatric urologist is the second Mayo staff member chosen to participate on NBC's TV show "American...

Plummer Building Figures Commemorate a Contentious Election - and a Friendship Carved in Stone #ThrowbackThursday - Insights

When the iconic Plummer Building was constructed on Mayo Clinic's Rochester campus during the late 1920s, the building's designer and namesake, Henry S. Plummer, M.D., made sure it included a number of bas relief caricatures that would help...

Mayo Clinic Laboratory and Pathology Research Roundup: Nov. 5 - Insights

This week’s Research Roundup highlights gastrointestinal and extra-intestinal manifestations of IgG4-related disease.

Mayo Clinic Laboratory and Pathology Research Roundup: July 16 - Insights

This week’s Research Roundup highlights how senolytics improve physical function and increase lifespan in old age.

Mayo Clinic Laboratory and Pathology Research Roundup: April 30 - Insights

This week’s Research Roundup highlights a model for predicting breast cancer risk in women with atypical hyperplasia.

Mayo Clinic Laboratory and pathology research roundup: August 9 - Insights

This week's research roundup features: Type 1, type 2 myocardial infarction and non-ischemic myocardial injury-opinion from the front lines

1863: Mayo and the Military #ThrowbackThursday - Insights

In May 1863, while the Battle of Chancellorsville was raging in Virginia and shortly before the climactic Battle of Gettysburg in Pennsylvania, an English-born, Minnesota-based physician named William Worrall Mayo, M.D., signed an oath of...

1879: Calling Dr. Mayo #ThrowbackThursday - Insights

May marks the fifth anniversary of the Mayo Clinic app—hailed by tech specialists and consumers alike as “what every patient app should be.” But Mayo’s leadership in telephone communications dates back much farther.

Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 30 - Insights

This week’s Research Roundup highlights rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease.

Mayo Clinic Laboratory and Pathology Research Roundup: Dec. 4 - Insights

This week’s Research Roundup highlights extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy.

Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 23 - Insights

This week’s Research Roundup highlights how human DBR1 modulates the recycling of snRNPs to affect alternative RNA splicing and contributes to the suppression of cancer development.

Mayo Clinic Laboratory and Pathology Research Roundup: Dec. 18 - Insights

This week’s Research Roundup highlights different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis.

Mayo Clinic Laboratory and Pathology Research Roundup: Nov. 6 - Insights

This week’s Research Roundup highlights an international assessment of event-free survival at 24 months and subsequent survival in peripheral T-cell lymphoma.

Mayo's Own American Ninja Warrior Returns to Competition - Insights

Age seems to slow most people down. But Andrew Yori, a.k.a. the K9 Ninja who competed in the "American Ninja Warrior" competition, isn't like most people. While Andrew didn't win, he did achieve raising awareness of shelter dogs and their...

From Dancing on Cans to Well-Oiled Machine: The Surprising Origins of Mayo's Recycling Program #ThrowbackThursday - Insights

Earth Day, Saturday, April 22, is one day when most folks pay particularly close attention to protecting the environment. This year, we're finding inspiration in the Sisters of Saint Francis who helped raise money for the Poverello Fund by...

Mayo Clinic Laboratory and pathology research roundup: December 27 - Insights

This week's research roundup features: Neuropathological findings in COVID-19: an autopsy cohort

Mayo Clinic Laboratory and pathology research roundup: November 29 - Insights

This week's research roundup features: AMPK: The key to ischemia-reperfusion injury

Pancreatic Elastase - Insights

Puanani Hopson, D.O., a Mayo Clinic pediatric gastroenterologist, explains the pancreatic elastase test — a screening test that can be useful when symptoms point to the possibility of exocrine pancreatic insufficiency. Dr. Hopson reviews...

Kelch-11 Autoantibody Test [Test in Focus] - Insights

Divyanshu (Div) Dubey, M.B.B.S., explains how Mayo Clinic Labs’ new Kelch-11 antibody test — the first in the world — can confirm diagnosis, guide treatment, and improve outcomes in patients affected by testicular cancer-associated...

Paraneoplastic Vision Loss Evaluation [Test in Focus] - Insights

Andrew McKeon, M,B., B.Ch., M.D., provides an overview of Mayo Clinic Laboratories' new paraneoplastic vision loss evaluation — a test that can help direct a cancer diagnosis and guide treatment. He reviews why this test was developed, when...

Staphylococcus species assay [Test in Focus] - Insights

Audrey Schuetz, M.D., discusses Mayo Clinic Laboratories' PCR assay that identifies two recently described staphylococcus species. The assay is unique in its ability to distinguish the new organisms from Staphylococcus aureus, providing...

SARS-CoV-2, Influenza A and B, and Respiratory Syncytial Virus (RSV) - Insights

Joseph Yao, M.D., explains how Mayo Clinic Laboratories’ SARS four-target test for viral respiratory disease can enhance patient care. The test detects RNA from SARS-CoV-2, influenza A, influenza B and respiratory syncytial virus, or RSV....

Appropriate Use of Gastrointestinal Pathogen Panel by PCR [Utilization Spotlight] - Insights

Infectious diarrhea is a common and usually self-limited illness. While most patients with infectious causes of diarrhea will get better on their own, there are certain scenarios in which testing is indicated. The The FilmArray...

Winter Storm Cora - Insights

Due to a pending winter storm affecting the FedEx hub in Memphis, Tennessee, and the UPS hub in Louisville, Kentucky, Mayo Clinic Laboratories will monitor and track the situation with our logistics partners to minimize challenges. Read...

Autoimmune Axonal Evaluation - Insights

Div Dubey, M.B.B.S., explains Mayo Clinic Laboratories' phenotypic testing approach for autoimmune axonal neuropathy. The comprehensive, serologic panel detects for antibodies with clinical relevance to the disease to provide clarity on...