Mayo Clinic Laboratory and pathology research roundup: August 2 - Insights
This week's research roundup features: Gastrointestinal stromal tumors mimicking gynecologic disease: clinicopathological analysis of 20 cases.
In a recent issue of Mayo Clinic's Digestive Diseases, Michael Camilleri, M.D., a gastroenterologist at Mayo Clinic, and Leslie Donato, Ph.D., Co-Director for Cardiovascular Laboratory Medicine, Hospital Clinical Laboratory, and Point of...
Working to Revive Interest in World War II History, One Jeep at a Time #ThrowbackThursday - Insights
Mayo Clinic cardiologist Gurpreet Sandhu, M.D., Ph.D., is on a one-man mission to restore interest in American and Indian history by bringing World War II Jeeps back to life.
Descendant of Mother Alfred Moes Visits Mayo Clinic #ThrowbackThursday - Insights
Last month, Mayo Clinic hosted a pair of distinguished visitors: Gerard and Margit Moes. The couple traveled from their home in Luxembourg to Rochester, Minnesota, to see and learn more about the place Gerard's ancestor, Mother Alfred Moes,...
Mayo Clinic Laboratory and Pathology Research Roundup: Jan. 14 - Insights
This week’s Research Roundup highlights the identification of prognostic phenotypes of esophageal adenocarcinoma in two independent cohorts.
Joseph Maleszewski, M.D., on Gene Testing in Cardiomyopathy Analysis in CAP Today - Insights
At the annual meeting of the Association for Molecular Pathology this past November, Joseph Maleszewski, M.D., a cardiovascular pathologist and Professor of Laboratory Medicine and Pathology at Mayo Clinic in Rochester, Minnesota, presented...
Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 27 - Insights
This week’s Research Roundup highlights a mechanism for preventing asymmetric histone segregation onto replicating DNA strands.
Mayo Clinic Laboratory and Pathology Research Roundup: July 30 - Insights
This week’s Research Roundup highlights a randomized trial of spheroid reservoir bioartificial liver in Porcine model of post-hepatectomy liver failure.
Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 3 - Insights
This week’s Research Roundup highlights biphenotypic acute leukemia versus myeloid antigen-positive ALL: Clinical relevance of WHO criteria for mixed phenotype acute leukemia.
Mayo Clinic Laboratory and Pathology Research Roundup: Feb. 19 - Insights
This week’s Research Roundup highlights the genomic analysis using regularized regression in high-grade serous ovarian cancer.
Mayo Clinic Laboratory and Pathology Research Roundup: April 9 - Insights
This week’s Research Roundup highlights genetic evidence for early peritoneal spreading in pelvic high-grade serous cancer.
Mayo Clinic Laboratory and Pathology Research Roundup: April 16 - Insights
This week’s Research Roundup highlights the clinical and pathological phenotype of genetic causes of focal segmental glomerulosclerosis in adults.
Mayo Clinic Laboratory and Pathology Research Roundup: April 2 - Insights
This week’s Research Roundup highlights patterns of homozygosity in patients with uniparental disomy with detection rate and suggested reporting thresholds for SNP microarrays.
Mayo Clinic Laboratory and Pathology Research Roundup: Feb. 12 - Insights
This week’s Research Roundup highlights the prediction of oncologic outcomes in Renal cell carcinoma after surgery.
Overcoming Fear of Public Speaking with "The Art of Laughter" - Insights
Nhien Chau, Clinical Laboratory Technologist in the Biochemical Genetics Laboratory at Mayo Clinic, decided to face his fear of public speaking by joining the Rochester Chamber Toastmasters group.
Mayo Clinic Laboratory and Pathology Research Roundup: Nov. 20 - Insights
This week’s Research Roundup highlights prehospital transfusion for gastrointestinal bleeding.
Plummer Building #ThrowbackThursday - Insights
Opened in 1928, the Plummer Building is an iconic symbol of Mayo Clinic, designated as a National Historic Landmark. It is named for Henry S. Plummer, M.D., the “diversified genius” who designed it and who created many of the systems and...
Mayo Clinic Laboratory and pathology research roundup: January 17 - Insights
This week's research roundup features: Exploring gene expression profiles in primary central nervous system vasculitis
Hunting Accident Leads to Memorable Mayo Experience #ThrowbackThursday - Insights
This story was told by Gary and Virginia Chalberg of Kingman, Arizona, who were visiting family at Mayo Clinic Hospital in Phoenix. While there, Gary, 84, asked if he could share the story of his dad’s first patient experience at Mayo...
The Mayos and Their Motorcars #ThrowbackThursday - Insights
Electric or gas-powered? It’s a question that drivers ponder as they weigh options for what kind of car to purchase. Charles Mayo, M.D., wrestled with a similar issue at the dawn of the 20th century. Moreover, Dr. Charlie had to consider...
Week in Review: April 29 - Insights
Today's highlights include: CDC estimates 3 in 4 kids have had coronavirus infections, virtual in-person cardiac rehabilitation provide similar benefits, and Mayo Clinic partners with AI startup to co-develop precision medicine.
Week in Review: April 22 - Insights
Today's highlights include: Study mines cancer genetics to help with targeted treatment, Mayo Clinic to launch staffing tool app to find 'right nurse for the right role', and new blood biomarker may lead to early diagnosis of frontotemporal...
Week in Review: May 6 - Insights
Today's highlights include: Mental health needs rise as pandemic fluctuates, an algorithm that analyzes apple watch data shows early promise in detecting heart problems, and Minnesota physicians brace for Roe v. Wade decision
Mayo Clinic Laboratory and Pathology Research Roundup: March 11 - Insights
This week’s Research Roundup highlights an assay to rapidly screen for immunoglobulin light chain glycosylation: a potential path to earlier AL diagnosis for a subset of patients and several other research articles by Mayo Clinic physicians...
Comprehensive genetic analysis for sarcoma fusions - Insights
Sarcomas are malignant tumors that arise in the bone and soft tissue. With numerous subtypes of sarcoma that can have overlapping histological, immunophenotypic, and clinical features, diagnosis can be extremely challenging
Hereditary Oncology Testing [Test in Focus] - Insights
Wei Shen, Ph.D., explains Mayo Clinic Laboratories' new expert-backed, hereditary oncology panels, which use next-generation sequencing to identify genetic mutations linked to increased cancer risk. By only including clinically significant...
New tests launched in November - Insights
In November 2022, Mayo Clinic Laboratories announced eighteen new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Updated testing algorithms for plasma cell proliferative disorders [Test in Focus] - Insights
Xinjie Xu, Ph.D., co-director of Mayo's Genetics and Genomics Laboratory, explains Mayo Clinic Laboratories' updated approach to testing for risk stratification of patients newly diagnosed with plasma cell proliferative disorders, such as...
New tests launched in July - Insights
In July 2022, Mayo Clinic Laboratories announced fifteen new tests along with numerous reference value changes, obsolete tests, and algorithm changes.
Neurofascin 155 IgG4 Antibody Test [Test in Focus] - Insights
John Mills, Ph.D., explains Mayo Clinic Laboratories' new neurofascin 155 (NF155) IgG4 antibody test, which is the first commercially available test in the U.S. to use flow cytometry to detect for NF155 antibodies and confirm diagnosis of...
Christmas and New Year's specimen shipment alert - Insights
Due to the Christmas and New Year's holiday's (recognized on Sunday, December 25th, and Sunday, January 1st ), Mayo Clinic Laboratories' specimen pickup and delivery schedules will be altered. To ensure that your specimen vitality and...
Thrombotic Microangiopathies (TMA) [Test in Focus] - Insights
Meera Sridharan, M.D., Ph.D., explains Mayo Clinic Labs’ testing approach for atypical hemolytic uremic syndrome (aHUS). The serological complement panel examines nine analytes to gain a thorough understanding of the complement cascade to...
Meet Me at the Microscope at USCAP 2020 - Insights
Mayo Clinic pathologists, researchers, and a wide spectrum of allied health staff will be in Los Angeles, California, for the 109th United States and Canadian Academy of Pathology Meeting (USCAP). Visit us at booth #716 on March 2 - 4, 2020...
Disaccharidase Activity Panel [Test in Focus] - Insights
Pua Hopson, D.O., discusses Mayo Clinic Labs’ new disaccharidase activity panel, which measures levels of five digestive enzymes to identify deficiencies that cause carbohydrate maldigestion and can lead to chronic conditions like celiac...
MAG Antibody Testing [Test in Focus] - Insights
John Mills, Ph.D., explains Mayo Clinic Laboratories’ approach to MAG antibody testing. The ELISA-based assay uses higher reference ranges and human MAG antigen to detect MAG antibodies, which are associated with a rare, hard-to-treat...
Sarcoma Targeted Gene Panel [Test in Focus] - Insights
Andre Oliveira, M.D., Ph.D., gives an overview of this testing available through Mayo Clinic Laboratories. He discusses when this testing should be ordered, how this testing compares to previous testing approaches, and what clinical action...
Building the business of lab medicine - Insights
In part three of the 50th Anniversary series, Mayo Clinic Laboratories looks further outside the walls of Mayo Clinic. With the belief that the latest in diagnostic testing should be available to any patient, no matter where they are...
MCL @Work: Jane Hermansen - Insights
Outreach manager Jane Hermansen regards Mayo Clinic as the pinnacle of healthcare. Having spent her formative years in Minnesota, she was inspired by her uncle Roger to embark on a path as a laboratory scientist. Presently, she oversees the...
Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 24 - Insights
This week’s Research Roundup highlights the limitations of platform assays to measure serum 25OHD level impact on guidelines and practice decision-making.
Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 22 - Insights
This week’s Research Roundup highlights neoantigenic potential of complex chromosomal rearrangements in mesothelioma.
Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 18 - Insights
This week’s Research Roundup highlights Mayo Clinic researchers who conducted a study to characterize the clinical, pathologic, and survival implications of non-V600 BRAF mutations in metastatic colorectal cancer.
Mayo Clinic Laboratory and Pathology Research Roundup: Oct. 16 - Insights
This week’s Research Roundup highlights the role of deficient DNA mismatch repair status in patients with stage III colon cancer treated with FOLFOX adjuvant chemotherapy.
Ann Moyer, M.D., Ph.D., Makes a Case for Pharmacogenomics - Insights
Pharmacogenomic testing is still limited, despite ample research, the existence of guidelines, and the emerging evidence it can help patients. Ann Moyer, M.D., Ph.D., Co-Director of the Personalized Genomics Laboratory at Mayo Clinic in...
Week in Review: November 15 - Insights
Top highlights include: deadly superbugs, evolution of patient safety, what to know about metabolic syndrome, and side effects of the flu shot.
Mayo Clinic Laboratory and Pathology Research Roundup: June 25 - Insights
This week’s Research Roundup highlights the association between inherited germline mutations in cancer predisposition genes and risk of pancreatic cancer.
Mayo Clinic Laboratory and Pathology Research Roundup: Jan. 15 - Insights
This week’s Research Roundup highlights how the loss of FOXO1 cooperates with TMPRSS2-ERG overexpression to promote prostate tumorigenesis and cell invasion.
Mayo Clinic Laboratory and Pathology Research Roundup: Sept. 4 - Insights
This week’s Research Roundup highlights individual patient-level meta-analysis of the performance of the Decipher genomic classifier in high-risk men after prostatectomy to predict development of metastatic disease.
Mayo Clinic Laboratory and Pathology Research Roundup: Aug. 21 - Insights
This week’s Research Roundup highlights how intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT-mTORC1 activation.
Mayo Clinic Laboratory and Pathology Research Roundup: April 10 - Insights
This week’s Research Roundup highlights thyroid hormone treatment among pregnant women with subclinical hypothyroidism.
Mayo Clinic Laboratory and Pathology Research Roundup: March 27 - Insights
This week’s Research Roundup highlights pathogenic implications of distinct patterns of iron and zinc in chronic multiple sclerosis lesions.